DK1713458T5 - Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen - Google Patents

Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen

Info

Publication number
DK1713458T5
DK1713458T5 DK05701734T DK05701734T DK1713458T5 DK 1713458 T5 DK1713458 T5 DK 1713458T5 DK 05701734 T DK05701734 T DK 05701734T DK 05701734 T DK05701734 T DK 05701734T DK 1713458 T5 DK1713458 T5 DK 1713458T5
Authority
DK
Denmark
Prior art keywords
bioavailability
enhancing
ospemifene
compound
stereoisomer
Prior art date
Application number
DK05701734T
Other languages
Danish (da)
English (en)
Other versions
DK1713458T3 (da
Inventor
Markku Anttila
Original Assignee
Hormos Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837941&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1713458(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hormos Medical Ltd filed Critical Hormos Medical Ltd
Publication of DK1713458T3 publication Critical patent/DK1713458T3/da
Application granted granted Critical
Publication of DK1713458T5 publication Critical patent/DK1713458T5/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DK05701734T 2004-02-13 2005-01-14 Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen DK1713458T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/777,211 US8236861B2 (en) 2004-02-13 2004-02-13 Method for enhancing the bioavailablity of ospemifene
PCT/FI2005/000018 WO2005077350A1 (fr) 2004-02-13 2005-01-14 Procede d'amelioration de la biodisponibilite d'ospemifene

Publications (2)

Publication Number Publication Date
DK1713458T3 DK1713458T3 (da) 2008-07-07
DK1713458T5 true DK1713458T5 (da) 2008-09-29

Family

ID=34837941

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05701734T DK1713458T5 (da) 2004-02-13 2005-01-14 Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen

Country Status (21)

Country Link
US (5) US8236861B2 (fr)
EP (1) EP1713458B1 (fr)
JP (2) JP5577011B2 (fr)
CN (1) CN1925847A (fr)
AT (1) ATE387910T1 (fr)
AU (1) AU2005211958B2 (fr)
BR (1) BRPI0507661A (fr)
CA (1) CA2556089C (fr)
CY (2) CY1111014T1 (fr)
DE (1) DE602005005165T2 (fr)
DK (1) DK1713458T5 (fr)
ES (1) ES2302177T3 (fr)
HU (1) HUS1500030I1 (fr)
LT (1) LTC1713458I2 (fr)
LU (1) LU92736I2 (fr)
MX (1) MXPA06009274A (fr)
NO (2) NO337656B1 (fr)
PL (1) PL1713458T3 (fr)
PT (1) PT1713458E (fr)
RU (1) RU2385716C2 (fr)
WO (1) WO2005077350A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236861B2 (en) 2004-02-13 2012-08-07 Hormos Medical Corporation Method for enhancing the bioavailablity of ospemifene
US8642079B2 (en) * 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US8758821B2 (en) * 2004-05-04 2014-06-24 Hormos Medical Ltd. Oral formulations of ospemifene
SI2275098T1 (sl) 2004-05-04 2012-12-31 Hormos Medical Ltd. Nove oralne formulacije ospemifena
CA2628964A1 (fr) * 2005-11-09 2007-09-07 Hormos Medical Ltd. Formulations de fispemifene
US9409856B2 (en) 2005-11-28 2016-08-09 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
MX2008006885A (es) * 2005-11-28 2008-10-20 Gtx Inc Agentes de enlace de receptores nucleares.
US8158828B2 (en) * 2005-11-28 2012-04-17 Gtx, Inc. Nuclear receptor binding agents
US8637706B2 (en) 2005-11-28 2014-01-28 Gtx, Inc. Nuclear receptor binding agents
US8546451B2 (en) 2005-11-28 2013-10-01 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US7504530B2 (en) * 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
ES2590262T3 (es) * 2007-02-14 2016-11-21 Hormos Medical Ltd. Método para la preparación de derivados de trifenilbuteno con valor terapéutico
US9427418B2 (en) 2009-02-23 2016-08-30 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US9624161B2 (en) 2009-02-23 2017-04-18 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
WO2014060639A1 (fr) 2012-10-19 2014-04-24 Fermion Oy Procédé pour la préparation d'ospémifène
CN103739456A (zh) * 2013-12-03 2014-04-23 镇江圣安医药有限公司 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用
GR1009542B (el) 2018-04-25 2019-06-07 Φαρματεν Α.Β.Ε.Ε. Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων
MD3790548T2 (ro) 2018-05-11 2024-02-29 Xenon Pharmaceuticals Inc Metode de îmbunătățire a biodisponibilității și expunerii activatorului de canale de potasiu voltaj-dependente

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9207437D0 (en) * 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites
GB9418067D0 (en) * 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
GB9604577D0 (en) 1996-03-04 1996-05-01 Orion Yhtymae Oy Serum cholesterol lowering agent
EP1102755B1 (fr) * 1998-08-07 2006-01-04 Chiron Corporation Isoxazoles substitues comme modulateurs de recepteur d'oestrogenes
US6219674B1 (en) * 1999-11-24 2001-04-17 Classen Immunotherapies, Inc. System for creating and managing proprietary product data
US6245819B1 (en) * 2000-07-21 2001-06-12 Hormos Medical Oy, Ltd. Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
US6653639B1 (en) * 2000-10-17 2003-11-25 Nikon Corporation Chuck for mounting reticle to a reticle stage
AU2002255593A1 (en) 2001-02-22 2002-09-12 Classen Immunotherapies, Inc. Improved algorithms and methods for products safety
FR2826811B1 (fr) 2001-06-27 2003-11-07 France Telecom Procede d'authentification cryptographique
UA79797C2 (en) 2002-06-06 2007-07-25 Hormos Medical Corp Method for the inhibition of atrophy or for treatment or prevention of atrophy-related symptoms in women
US8236861B2 (en) * 2004-02-13 2012-08-07 Hormos Medical Corporation Method for enhancing the bioavailablity of ospemifene
US20050187302A1 (en) * 2004-02-23 2005-08-25 Hormos Medical Corporation Method for treatment or prevention of osteoporosis in individuals with high bone turnover
US8642079B2 (en) * 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US8758821B2 (en) * 2004-05-04 2014-06-24 Hormos Medical Ltd. Oral formulations of ospemifene
US20060293294A1 (en) 2004-09-03 2006-12-28 Hormos Medical Corporation Method for treatment or prevention of androgen deficiency

Also Published As

Publication number Publication date
US20050182143A1 (en) 2005-08-18
RU2006132719A (ru) 2008-03-20
CN1925847A (zh) 2007-03-07
US20120270952A1 (en) 2012-10-25
NO20151603L (no) 2006-11-03
NO337656B1 (no) 2016-05-23
CY1111014T1 (el) 2015-06-11
US20140303259A1 (en) 2014-10-09
NO20063960L (no) 2006-11-03
DK1713458T3 (da) 2008-07-07
US9241915B2 (en) 2016-01-26
PT1713458E (pt) 2008-05-07
CA2556089C (fr) 2013-04-02
DE602005005165T2 (de) 2009-04-30
CY2015027I2 (el) 2016-04-13
CY2015027I1 (el) 2016-04-13
LTPA2015023I1 (lt) 2015-08-25
JP2007522190A (ja) 2007-08-09
US8236861B2 (en) 2012-08-07
EP1713458B1 (fr) 2008-03-05
LU92736I2 (fr) 2015-08-10
BRPI0507661A (pt) 2007-07-17
ES2302177T3 (es) 2008-07-01
WO2005077350A1 (fr) 2005-08-25
DE602005005165D1 (de) 2008-04-17
US20160101065A1 (en) 2016-04-14
US9855224B2 (en) 2018-01-02
CA2556089A1 (fr) 2005-08-25
JP2014141533A (ja) 2014-08-07
US8772353B2 (en) 2014-07-08
EP1713458A1 (fr) 2006-10-25
US8470890B2 (en) 2013-06-25
US20130324614A1 (en) 2013-12-05
RU2385716C2 (ru) 2010-04-10
JP6023119B2 (ja) 2016-11-09
LTC1713458I2 (lt) 2017-06-26
ATE387910T1 (de) 2008-03-15
NO339190B1 (no) 2016-11-14
MXPA06009274A (es) 2007-04-16
PL1713458T3 (pl) 2008-08-29
AU2005211958B2 (en) 2010-11-25
AU2005211958A1 (en) 2005-08-25
HUS1500030I1 (hu) 2015-08-28
JP5577011B2 (ja) 2014-08-20

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