DK1791537T3 - 3-arylthioindol-2-carboxamidderivater og analoger deraf som inhibitorer af casein-kinase - Google Patents
3-arylthioindol-2-carboxamidderivater og analoger deraf som inhibitorer af casein-kinaseInfo
- Publication number
- DK1791537T3 DK1791537T3 DK05785433.3T DK05785433T DK1791537T3 DK 1791537 T3 DK1791537 T3 DK 1791537T3 DK 05785433 T DK05785433 T DK 05785433T DK 1791537 T3 DK1791537 T3 DK 1791537T3
- Authority
- DK
- Denmark
- Prior art keywords
- casein kinase
- arylthioindole
- analogues
- inhibitors
- carboxamide derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60334804P | 2004-08-19 | 2004-08-19 | |
| PCT/US2005/029306 WO2006023590A1 (en) | 2004-08-19 | 2005-08-19 | 3-ARYLTHIOINDOLE-2-CARBOXAMIDE DERIVATIVES AND ANALOGS THEREOF AS INHIBITORS OF CASEIN KINASE Iϵ |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1791537T3 true DK1791537T3 (da) | 2010-03-01 |
Family
ID=35311784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05785433.3T DK1791537T3 (da) | 2004-08-19 | 2005-08-19 | 3-arylthioindol-2-carboxamidderivater og analoger deraf som inhibitorer af casein-kinase |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8008340B2 (da) |
| EP (1) | EP1791537B1 (da) |
| JP (1) | JP4931814B2 (da) |
| KR (1) | KR20070045264A (da) |
| CN (1) | CN101039666A (da) |
| AT (1) | ATE445396T1 (da) |
| AU (1) | AU2005277460A1 (da) |
| BR (1) | BRPI0514397A (da) |
| CA (1) | CA2577511A1 (da) |
| DE (1) | DE602005017162D1 (da) |
| DK (1) | DK1791537T3 (da) |
| ES (1) | ES2334927T3 (da) |
| IL (1) | IL181155A0 (da) |
| MX (1) | MX2007001077A (da) |
| PL (1) | PL1791537T3 (da) |
| PT (1) | PT1791537E (da) |
| RU (1) | RU2391098C2 (da) |
| SI (1) | SI1791537T1 (da) |
| WO (1) | WO2006023590A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0908851A2 (pt) * | 2008-02-22 | 2017-05-30 | Irm Llc | compostos e composições como moduladores da atividades de gpr119 |
| EP2397481B1 (en) * | 2009-02-12 | 2014-03-12 | Pharmadesign, Inc. | Inhibitor of casein kinase 1delta and casein kinase 1epsilon |
| WO2011051858A1 (en) * | 2009-10-28 | 2011-05-05 | Pfizer Inc. | Imidazole derivatives as casein kinase inhibitors |
| CA2797281A1 (en) * | 2010-05-06 | 2011-11-10 | Merck Sharp & Dohme Corp. | Aza-indole derivatives useful as modulators of faah |
| KR101856266B1 (ko) * | 2010-08-09 | 2018-05-09 | 가부시키가이샤 에누비 켄코우겡큐쇼 | 카세인 키나아제 1δ 및 카세인 키나아제 1ε 저해제 |
| KR101350077B1 (ko) * | 2010-12-13 | 2014-01-14 | 한국화학연구원 | 신규한 3-인돌리논 유도체 및 이를 포함하는 조성물 |
| US20140031547A1 (en) * | 2010-12-14 | 2014-01-30 | Electrophoretics Limited | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODE-GENERATIVE DISEASES SUCH AS TAUOPATHIES |
| TWI601714B (zh) | 2012-05-11 | 2017-10-11 | 重植治療公司 | 隱花色素調節劑之含咔唑磺醯胺類 |
| TWI690521B (zh) | 2014-04-07 | 2020-04-11 | 美商同步製藥公司 | 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類 |
| WO2018133835A1 (en) * | 2017-01-20 | 2018-07-26 | National Institute Of Biological Sciences, Beijing | Nucleoside analogue regulating mammalian circadian rhythm |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3705934A1 (de) * | 1987-02-25 | 1988-09-08 | Nattermann A & Cie | Indolyl-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| CA2156420A1 (en) * | 1993-02-24 | 1994-09-01 | Theresa M. Williams | Inhibitors of hiv reverse transcriptase |
| BR0011437A (pt) * | 1999-06-08 | 2002-03-05 | Aventis Pharma Inc | Métodos de triagem para alterar proteìnas do ritmo circadiano |
| EP1485384A1 (en) * | 2002-03-13 | 2004-12-15 | Pharmacia & Upjohn Company LLC | Pyrazolo(1,5-a)pyridine derivatives as neurotransmitter modulators |
| WO2004014300A2 (en) * | 2002-08-09 | 2004-02-19 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| CN100439367C (zh) * | 2003-12-11 | 2008-12-03 | 安万特药物公司 | 作为酪蛋白激酶Iε抑制剂的取代的1H-吡咯并[3,2-b、3,2-c和2,3-c]吡啶-2-甲酰胺以及相关类似物 |
-
2005
- 2005-08-19 CA CA002577511A patent/CA2577511A1/en not_active Abandoned
- 2005-08-19 AT AT05785433T patent/ATE445396T1/de not_active IP Right Cessation
- 2005-08-19 PL PL05785433T patent/PL1791537T3/pl unknown
- 2005-08-19 MX MX2007001077A patent/MX2007001077A/es not_active Application Discontinuation
- 2005-08-19 KR KR1020077003924A patent/KR20070045264A/ko not_active Application Discontinuation
- 2005-08-19 JP JP2007527987A patent/JP4931814B2/ja not_active Expired - Fee Related
- 2005-08-19 WO PCT/US2005/029306 patent/WO2006023590A1/en active Application Filing
- 2005-08-19 BR BRPI0514397-7A patent/BRPI0514397A/pt not_active IP Right Cessation
- 2005-08-19 AU AU2005277460A patent/AU2005277460A1/en not_active Abandoned
- 2005-08-19 DE DE602005017162T patent/DE602005017162D1/de active Active
- 2005-08-19 ES ES05785433T patent/ES2334927T3/es active Active
- 2005-08-19 PT PT05785433T patent/PT1791537E/pt unknown
- 2005-08-19 DK DK05785433.3T patent/DK1791537T3/da active
- 2005-08-19 RU RU2007109813/14A patent/RU2391098C2/ru not_active IP Right Cessation
- 2005-08-19 EP EP05785433A patent/EP1791537B1/en not_active Not-in-force
- 2005-08-19 SI SI200530889T patent/SI1791537T1/sl unknown
- 2005-08-19 CN CNA2005800346526A patent/CN101039666A/zh active Pending
-
2007
- 2007-02-04 IL IL181155A patent/IL181155A0/en unknown
- 2007-02-15 US US11/675,230 patent/US8008340B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0514397A (pt) | 2008-06-10 |
| JP4931814B2 (ja) | 2012-05-16 |
| MX2007001077A (es) | 2007-04-17 |
| RU2391098C2 (ru) | 2010-06-10 |
| US20070142454A1 (en) | 2007-06-21 |
| CN101039666A (zh) | 2007-09-19 |
| KR20070045264A (ko) | 2007-05-02 |
| US8008340B2 (en) | 2011-08-30 |
| EP1791537B1 (en) | 2009-10-14 |
| SI1791537T1 (sl) | 2010-02-26 |
| IL181155A0 (en) | 2007-07-04 |
| AU2005277460A1 (en) | 2006-03-02 |
| ES2334927T3 (es) | 2010-03-17 |
| PT1791537E (pt) | 2010-01-19 |
| WO2006023590A1 (en) | 2006-03-02 |
| PL1791537T3 (pl) | 2010-04-30 |
| JP2008510704A (ja) | 2008-04-10 |
| CA2577511A1 (en) | 2006-03-02 |
| RU2007109813A (ru) | 2008-09-27 |
| EP1791537A1 (en) | 2007-06-06 |
| DE602005017162D1 (de) | 2009-11-26 |
| ATE445396T1 (de) | 2009-10-15 |
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