DK170714B1 - Rekombinant DNA-vektor, fremgangsmåde til fremstilling deraf, værter transformeret dermed, fremgangsmåde til fremstilling af transformeret vært samt fremgangsmåde til fremstilling af et lymfoblastoidtalfa-interferon - Google Patents

Rekombinant DNA-vektor, fremgangsmåde til fremstilling deraf, værter transformeret dermed, fremgangsmåde til fremstilling af transformeret vært samt fremgangsmåde til fremstilling af et lymfoblastoidtalfa-interferon Download PDF

Info

Publication number
DK170714B1
DK170714B1 DK437382A DK437382A DK170714B1 DK 170714 B1 DK170714 B1 DK 170714B1 DK 437382 A DK437382 A DK 437382A DK 437382 A DK437382 A DK 437382A DK 170714 B1 DK170714 B1 DK 170714B1
Authority
DK
Denmark
Prior art keywords
dna
pbr
cdna
cells
ifn
Prior art date
Application number
DK437382A
Other languages
Danish (da)
English (en)
Other versions
DK437382A (da
Inventor
Francois Meyer
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27261323&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK170714(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK437382A publication Critical patent/DK437382A/da
Application granted granted Critical
Publication of DK170714B1 publication Critical patent/DK170714B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK437382A 1981-10-03 1982-10-01 Rekombinant DNA-vektor, fremgangsmåde til fremstilling deraf, værter transformeret dermed, fremgangsmåde til fremstilling af transformeret vært samt fremgangsmåde til fremstilling af et lymfoblastoidtalfa-interferon DK170714B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8129937 1981-10-03
GB8129937 1981-10-03
GB8208988 1982-03-26
GB8208988 1982-03-26
GB8224871 1982-09-01
GB08224871A GB2108510B (en) 1981-10-03 1982-09-01 Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof

Publications (2)

Publication Number Publication Date
DK437382A DK437382A (da) 1983-04-04
DK170714B1 true DK170714B1 (da) 1995-12-18

Family

ID=27261323

Family Applications (1)

Application Number Title Priority Date Filing Date
DK437382A DK170714B1 (da) 1981-10-03 1982-10-01 Rekombinant DNA-vektor, fremgangsmåde til fremstilling deraf, værter transformeret dermed, fremgangsmåde til fremstilling af transformeret vært samt fremgangsmåde til fremstilling af et lymfoblastoidtalfa-interferon

Country Status (19)

Country Link
US (1) US5089400A (US07122547-20061017-C00273.png)
EP (1) EP0076489B1 (US07122547-20061017-C00273.png)
JP (2) JPH06104066B2 (US07122547-20061017-C00273.png)
KR (1) KR920007665B1 (US07122547-20061017-C00273.png)
AU (1) AU561104B2 (US07122547-20061017-C00273.png)
DD (1) DD204266A5 (US07122547-20061017-C00273.png)
DE (1) DE3280174D1 (US07122547-20061017-C00273.png)
DK (1) DK170714B1 (US07122547-20061017-C00273.png)
ES (2) ES516154A0 (US07122547-20061017-C00273.png)
FI (1) FI80719C (US07122547-20061017-C00273.png)
GB (1) GB2108510B (US07122547-20061017-C00273.png)
GR (1) GR76992B (US07122547-20061017-C00273.png)
HU (1) HU197047B (US07122547-20061017-C00273.png)
IE (1) IE54051B1 (US07122547-20061017-C00273.png)
IL (1) IL66920A0 (US07122547-20061017-C00273.png)
NO (1) NO166494C (US07122547-20061017-C00273.png)
NZ (1) NZ202058A (US07122547-20061017-C00273.png)
PH (2) PH21524A (US07122547-20061017-C00273.png)
PT (1) PT75643B (US07122547-20061017-C00273.png)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
DE3220116A1 (de) 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
NZ205924A (en) * 1982-10-11 1987-07-31 Nat Biolog Standards Board Synthetic polypeptide: fragment of structural capsid protein; vaccine; method for diagnosis
IE56509B1 (en) * 1982-11-04 1991-08-28 Univ California Methods for oncogenic detection
JPS60118196A (ja) * 1983-11-30 1985-06-25 Takeda Chem Ind Ltd インタ−フェロンの製造法
JPS6156199A (ja) * 1984-08-27 1986-03-20 Shionogi & Co Ltd 新規ヒトインタ−フエロンα類
EP0194006B1 (en) * 1985-02-01 1992-04-29 Imperial Chemical Industries Plc Analogous interferon polypeptides, process for their preparation and pharmaceutical compositions containing them
GB8508685D0 (en) * 1985-04-03 1985-05-09 Minor P D Peptides
EP0200417B1 (en) * 1985-04-30 1992-10-21 Takeda Chemical Industries, Ltd. Production of protein
ATE78262T1 (de) * 1985-06-11 1992-08-15 Ciba Geigy Ag Hybrid-interferone.
ATE125304T1 (de) 1986-04-15 1995-08-15 Ciba Geigy Ag Monoklonale antikörper gegen interferon- induziertes humanes protein in gereignigter form, und diese antikörper enthaltende testsätze.
TW218846B (US07122547-20061017-C00273.png) * 1992-04-07 1994-01-11 Ciba Geigy
US5733733A (en) * 1992-08-04 1998-03-31 Replicon, Inc. Methods for the isothermal amplification of nucleic acid molecules
US6261808B1 (en) 1992-08-04 2001-07-17 Replicon, Inc. Amplification of nucleic acid molecules via circular replicons
US5834202A (en) 1992-08-04 1998-11-10 Replicon, Inc. Methods for the isothermal amplification of nucleic acid molecules
WO1994003624A1 (en) * 1992-08-04 1994-02-17 Auerbach Jeffrey I Methods for the isothermal amplification of nucleic acid molecules
US20020102236A1 (en) * 1994-12-08 2002-08-01 Taylor Peter William Liposomal interferon hybrid compositions
EP0801682B1 (en) 1995-02-09 2001-10-24 Novartis AG Process for the production of proteins
US6087102A (en) * 1998-01-07 2000-07-11 Clontech Laboratories, Inc. Polymeric arrays and methods for their use in binding assays
US6685933B1 (en) * 1998-07-28 2004-02-03 The United States Of America As Represented By The Department Of Health And Human Services Interferon α hybrids
DE19919149A1 (de) * 1999-04-27 2000-11-16 Wieser Raimund J Von Interferon alpha-2 abgeleitete Peptid-Homodimere und Peptid-Heterodimere
WO2002036627A2 (en) * 2000-11-03 2002-05-10 Pbl Biomedical Laboratories Interferons, uses and compositions related thereto
WO2002088161A1 (en) * 2001-05-02 2002-11-07 Pepgen Corporation Method for expression of human interferon alpha 1 in pichia pa storis
FR2825716B1 (fr) 2001-06-11 2004-09-24 Genodyssee Nouveaux polynucleotides et polypeptides de l'ifn alpha 7
DE602005026854D1 (de) * 2004-12-20 2011-04-21 Cadila Healthcare Ltd Verfahren zur herstellung von hohen niveaus von interferon-beta
CN110172309B (zh) 2016-11-21 2022-08-16 日东电工株式会社 粘合片
KR102055078B1 (ko) 2016-11-21 2019-12-11 닛토덴코 가부시키가이샤 점착 시트

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA796175B (en) * 1978-11-24 1980-11-26 Hoffmann La Roche Purified proteins and process therefor
AU538665B2 (en) * 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
CY1346A (en) * 1980-01-08 1987-01-16 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human interferon-like polypeptides
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
KR860001471B1 (ko) * 1980-04-03 1986-09-26 비오겐 엔. 브이 인체의 섬유아세포 인터페론(IFN-β)폴리펩티드의 제조방법
EP0042246B1 (en) * 1980-06-12 1987-03-18 The Cancer Institute Of Japanese Foundation For Cancer Research Plasmid
ES8302778A1 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof

Also Published As

Publication number Publication date
JPS5890596A (ja) 1983-05-30
FI80719B (fi) 1990-03-30
ES528141A0 (es) 1985-11-01
ES8601237A1 (es) 1985-11-01
FI823356A0 (fi) 1982-10-01
JPH06104066B2 (ja) 1994-12-21
GB2108510A (en) 1983-05-18
PT75643B (en) 1986-11-13
PH21524A (en) 1987-11-16
NO823314L (no) 1983-04-05
NO166494C (no) 1991-08-07
PH23119A (en) 1989-05-05
GB2108510B (en) 1984-12-12
EP0076489A3 (en) 1984-03-28
EP0076489A2 (de) 1983-04-13
ES8504936A1 (es) 1985-04-16
JP2612149B2 (ja) 1997-05-21
ES516154A0 (es) 1985-04-16
DD204266A5 (de) 1983-11-23
IE822385L (en) 1983-04-30
GR76992B (US07122547-20061017-C00273.png) 1984-09-04
AU561104B2 (en) 1987-04-30
NO166494B (no) 1991-04-22
NZ202058A (en) 1986-05-09
IL66920A0 (en) 1982-12-31
IE54051B1 (en) 1989-05-24
EP0076489B1 (de) 1990-05-16
PT75643A (en) 1982-11-01
JPH07173195A (ja) 1995-07-11
KR840002031A (ko) 1984-06-11
FI823356L (fi) 1983-04-04
HU197047B (en) 1989-02-28
DE3280174D1 (de) 1990-06-21
US5089400A (en) 1992-02-18
KR920007665B1 (ko) 1992-09-14
DK437382A (da) 1983-04-04
FI80719C (fi) 1990-07-10
AU8895882A (en) 1983-04-14

Similar Documents

Publication Publication Date Title
DK170714B1 (da) Rekombinant DNA-vektor, fremgangsmåde til fremstilling deraf, værter transformeret dermed, fremgangsmåde til fremstilling af transformeret vært samt fremgangsmåde til fremstilling af et lymfoblastoidtalfa-interferon
EP0205404B1 (en) Hybrid interferons
CA1341240C (en) Dna encoding human tumor necrosis factor and human tumor necrosis factor polypeptide
JP2642291B2 (ja) ハイブリド型ヒト白血球インタフェロンをコードするｄｎａ
US4530901A (en) Recombinant DNA molecules and their use in producing human interferon-like polypeptides
KR860001471B1 (ko) 인체의 섬유아세포 인터페론(IFN-β)폴리펩티드의 제조방법
US5487984A (en) Processes for producing tumor necrosis factor
FI86992C (fi) Foerfarande foer framstaellning human tumoernekrosfaktor och plasmid anvaend vid foerfarandet
US5004689A (en) DNA sequences, recombinant DNA molecules and processes for producing human gamma interferon-like polypeptides in high yields
HU193512B (en) Process for preparing hybride interferones from human erythrocytes
HU194305B (en) Process for production of dns sequences, recombinated dns molecules and human interferon-type polipeptides
CS273152B2 (en) Method of mature human leucocytic interferon production
DK164063B (da) Fremgangsmaade til fremstilling af praktisk taget rent uglycosyleret rekombinant humant immuninterferonprotein
US4801685A (en) Microbial production of mature human leukocyte interferon K and L
Mizoguchi et al. Efficient expression in Escherichia coli of two species of human interferon-α and their hybrid molecules
JPS6361920B2 (US07122547-20061017-C00273.png)
JPS6156199A (ja) 新規ヒトインタ−フエロンα類
JPH0822230B2 (ja) アルファ―インターフェロンｇｘ―１
JPH06220099A (ja) 可溶性ｌｄｌリセプター
US7235232B2 (en) Interferon alpha hybrids
KR870000510B1 (ko) 형질전환된 미생물의 제조방법
KR890001828B1 (ko) 인터페론-α형의 폴리펩티드의 제조방법
Goeddel Microbial production of mature human leukocyte interferons
NZ227372A (en) Murine monoclonal antibodies to human ifnalpha
CS273182B2 (en) Method of expressive vector production capable to give mature human leucocytic interferon in transformed strain of escherichia coli by means of expression

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed