DK170338B1 - Fremgangsmåde til fremstilling af 1,3-dihydro-4-pyridoyl-2H-imidazol-2-oner - Google Patents

Fremgangsmåde til fremstilling af 1,3-dihydro-4-pyridoyl-2H-imidazol-2-oner Download PDF

Info

Publication number
DK170338B1
DK170338B1 DK343985A DK343985A DK170338B1 DK 170338 B1 DK170338 B1 DK 170338B1 DK 343985 A DK343985 A DK 343985A DK 343985 A DK343985 A DK 343985A DK 170338 B1 DK170338 B1 DK 170338B1
Authority
DK
Denmark
Prior art keywords
pyridyl
acid
hydroxy
imidazol
dihydro
Prior art date
Application number
DK343985A
Other languages
Danish (da)
English (en)
Other versions
DK343985D0 (da
DK343985A (da
Inventor
Richard A Schnettler
Chi-Hsin R King
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK343985D0 publication Critical patent/DK343985D0/da
Publication of DK343985A publication Critical patent/DK343985A/da
Application granted granted Critical
Publication of DK170338B1 publication Critical patent/DK170338B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/48Aldehydo radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK343985A 1984-07-30 1985-07-29 Fremgangsmåde til fremstilling af 1,3-dihydro-4-pyridoyl-2H-imidazol-2-oner DK170338B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63585284A 1984-07-30 1984-07-30
US63585284 1984-07-30

Publications (3)

Publication Number Publication Date
DK343985D0 DK343985D0 (da) 1985-07-29
DK343985A DK343985A (da) 1986-01-31
DK170338B1 true DK170338B1 (da) 1995-08-07

Family

ID=24549382

Family Applications (2)

Application Number Title Priority Date Filing Date
DK343985A DK170338B1 (da) 1984-07-30 1985-07-29 Fremgangsmåde til fremstilling af 1,3-dihydro-4-pyridoyl-2H-imidazol-2-oner
DK137290A DK170163B1 (da) 1984-07-30 1990-06-01 Fremgangsmåde til fremstilling af 1,3-dihydro-4-pyridoyl-2H-imidazol-2-oner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK137290A DK170163B1 (da) 1984-07-30 1990-06-01 Fremgangsmåde til fremstilling af 1,3-dihydro-4-pyridoyl-2H-imidazol-2-oner

Country Status (19)

Country Link
EP (1) EP0170214B1 (hu)
JP (1) JPH0696573B2 (hu)
KR (1) KR910006636B1 (hu)
AT (1) ATE46330T1 (hu)
AU (1) AU579389B2 (hu)
CA (1) CA1262732C (hu)
DE (1) DE3572973D1 (hu)
DK (2) DK170338B1 (hu)
ES (1) ES8603839A1 (hu)
FI (1) FI85271C (hu)
GR (1) GR851846B (hu)
HU (2) HU196996B (hu)
IE (1) IE58075B1 (hu)
IL (1) IL75902A (hu)
NO (1) NO163955C (hu)
NZ (1) NZ212870A (hu)
PH (2) PH25128A (hu)
PT (1) PT80883B (hu)
ZA (1) ZA855592B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11209375A (ja) * 1998-01-23 1999-08-03 Nippon Bayer Agrochem Co Ltd 複素環置換アルコール誘導体及び農園芸用殺菌剤
DE19858352A1 (de) 1998-12-17 2000-06-21 Basf Ag Verfahren zum Herstellen von 2,4-Dimethyl-3,5-bis-alkoxycarbonyl-pyrrol
CN103214422B (zh) * 2013-05-07 2015-07-15 南通大学 一类新型取代胺基咪唑酮衍生物的制备方法及抗癌作用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use

Also Published As

Publication number Publication date
JPS6143167A (ja) 1986-03-01
IE851893L (en) 1986-01-30
FI852923L (fi) 1986-01-31
NZ212870A (en) 1988-10-28
ES545670A0 (es) 1986-01-01
PH25128A (en) 1991-02-19
FI85271B (fi) 1991-12-13
HU194553B (en) 1988-02-29
ZA855592B (en) 1986-03-26
CA1262732A (en) 1989-11-07
DK137290A (da) 1990-06-01
ATE46330T1 (de) 1989-09-15
NO163955C (no) 1990-08-15
GR851846B (hu) 1985-12-02
PT80883B (pt) 1987-09-18
DK137290D0 (da) 1990-06-01
DK170163B1 (da) 1995-06-06
KR860001101A (ko) 1986-02-22
JPH0696573B2 (ja) 1994-11-30
DE3572973D1 (en) 1989-10-19
DK343985D0 (da) 1985-07-29
IL75902A (en) 1988-10-31
KR910006636B1 (ko) 1991-08-29
IL75902A0 (en) 1985-12-31
EP0170214B1 (en) 1989-09-13
FI852923A0 (fi) 1985-07-26
FI85271C (fi) 1992-03-25
PT80883A (en) 1985-08-01
PH25683A (en) 1991-09-04
ES8603839A1 (es) 1986-01-01
EP0170214A1 (en) 1986-02-05
NO852995L (no) 1986-01-31
NO163955B (no) 1990-05-07
DK343985A (da) 1986-01-31
AU4553985A (en) 1986-02-06
HU196996B (en) 1989-02-28
IE58075B1 (en) 1993-06-30
HUT38334A (en) 1986-05-28
CA1262732C (en) 1989-11-07
AU579389B2 (en) 1988-11-24

Similar Documents

Publication Publication Date Title
JP4399163B2 (ja) N−(1−ヒドロキシメチル−2,3−ジヒドロキシプロピル)−1,4,7−トリスカルボキシメチル−1,4,7,10−テトラアザシクロドデカンのリチウム錯体、その製造及び使用
DK170338B1 (da) Fremgangsmåde til fremstilling af 1,3-dihydro-4-pyridoyl-2H-imidazol-2-oner
PL87801B1 (en) Amino pyrimidines[us3635978a]
JP2003508517A (ja) キノロンカルボン酸誘導体の製造に関する中間体
JPH0136462B2 (hu)
US20040053967A1 (en) 3-(3-Amidinophenyl)-5-[({[1-(1-(iminoethyl)-4-piperidyl}amino)methyl]benzoic acid dihydrochloride and process for preparing the same
JP2851162B2 (ja) 低塩化物イオン1,2,4―トリアゾール―5―オンの改良製造方法
JPH07116153B2 (ja) ピリジン−2,3−ジカルボン酸類の製造方法
US4803278A (en) Preparation of 1,3-dihydro-4-pyridoyl-2H-imidazol-2-ones
US3245998A (en) Processes for the production of picolinic acid dericatives
JP2565372B2 (ja) チオール化合物の製造方法
JPH0665244A (ja) リボフラビンの精製法
JP4032825B2 (ja) 3,4−ジヒドロキシベンゾニトリルを製造する方法
JPH09509185A (ja) 6−アリールオキシメチル−1−ヒドロキシ−4−メチル−2−ピリドンの製法
SU1348338A1 (ru) Способ получени 1,4-дигидро-3R-1,2,4-триазол-5-онов
JPH093048A (ja) 置換8−クロロキノリン類の置換8−ヒドロキシキノリン類への転化
JPS5993059A (ja) シトシン類の製法
SU360774A1 (ru) Способ получения 2
CN116375657A (zh) 一种来曲唑杂质a的制备方法
JP2000344751A (ja) 2,3−ピリジンジカルボン酸類の製造方法
JPS5993060A (ja) シトシン類の製法
PL97325B1 (pl) Sposob wytwarzania 3,4-dwuwodoro-1(2h)-ftalazynonu
AU2002226745A1 (en) 3-(3-amidinophenyl)-5-(({(1-(1-(-iminoethyl)-4-piperidyl}amino)methyl)benzoic acid dihydrochloride and process for preparing the same
JPS6411019B2 (hu)
JPS6139942B2 (hu)

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed