DK170099B1 - t-Butyl-ergolin-derivativer, fremgangsmåde til fremstilling deraf, samt farmaceutiske præparater indeholdende disse - Google Patents
t-Butyl-ergolin-derivativer, fremgangsmåde til fremstilling deraf, samt farmaceutiske præparater indeholdende disse Download PDFInfo
- Publication number
- DK170099B1 DK170099B1 DK322587A DK322587A DK170099B1 DK 170099 B1 DK170099 B1 DK 170099B1 DK 322587 A DK322587 A DK 322587A DK 322587 A DK322587 A DK 322587A DK 170099 B1 DK170099 B1 DK 170099B1
- Authority
- DK
- Denmark
- Prior art keywords
- ergoline
- butyl
- formula
- methyl
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Developing Agents For Electrophotography (AREA)
- Liquid Developers In Electrophotography (AREA)
- Graft Or Block Polymers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868615471A GB8615471D0 (en) | 1986-06-25 | 1986-06-25 | T-butyl ergoline derivatives |
GB8615471 | 1986-06-25 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK322587D0 DK322587D0 (da) | 1987-06-24 |
DK322587A DK322587A (da) | 1987-12-26 |
DK170099B1 true DK170099B1 (da) | 1995-05-22 |
Family
ID=10600059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK322587A DK170099B1 (da) | 1986-06-25 | 1987-06-24 | t-Butyl-ergolin-derivativer, fremgangsmåde til fremstilling deraf, samt farmaceutiske præparater indeholdende disse |
Country Status (20)
Country | Link |
---|---|
US (2) | US4843073A (ko) |
EP (1) | EP0251652B1 (ko) |
JP (1) | JPH0745498B2 (ko) |
KR (1) | KR950008970B1 (ko) |
AT (1) | ATE76407T1 (ko) |
AU (1) | AU597672B2 (ko) |
CA (1) | CA1339533C (ko) |
DE (1) | DE3779190D1 (ko) |
DK (1) | DK170099B1 (ko) |
ES (1) | ES2042567T3 (ko) |
FI (1) | FI85702C (ko) |
GB (1) | GB8615471D0 (ko) |
GR (1) | GR3005115T3 (ko) |
HU (1) | HU196201B (ko) |
IE (1) | IE61319B1 (ko) |
IL (1) | IL82946A (ko) |
NZ (1) | NZ220543A (ko) |
PT (1) | PT85152B (ko) |
SU (1) | SU1547708A3 (ko) |
ZA (1) | ZA874569B (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61245164A (ja) * | 1985-04-23 | 1986-10-31 | Seiko Instr & Electronics Ltd | パタ−ン修正装置 |
HU193782B (en) * | 1985-06-21 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof |
US6060483A (en) * | 1996-06-27 | 2000-05-09 | Pharmacia & Upjohn S.P.A. | Antineurodegenerative ergoline derivatives |
WO2014195849A2 (en) * | 2013-06-03 | 2014-12-11 | Mahesh Kandula | Compositions and methods for the treatment of cerebrovascular diseases |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3228945A (en) * | 1966-01-11 | Methyl and i,g-dimethyl-b-(a-hydroxy- alkyl)-ergoline i derivatives | ||
US3228942A (en) * | 1966-01-11 | Methyl and i,g-dimeti-iyl ergoline i compounds | ||
US3228941A (en) * | 1966-01-11 | Methyl and i,g-dimethyl-ergoline i derivatives | ||
DE203721C (ko) * | 1908-05-05 | |||
US3232942A (en) * | 1964-06-02 | 1966-02-01 | Sandoz Ltd | 1-substituted (+)-lysergol |
US3879554A (en) * | 1970-03-20 | 1975-04-22 | Farmaceutici Italia | Use of 1,6-dimethyl-8-{62 -(5-bromonicotinoyloxymethyl)-10 {60 -methoxyergoline in treating cerebral and peripheral metabolic vascular disorders |
USRE30218E (en) * | 1974-12-06 | 1980-02-19 | Eli Lilly And Company | 8,8-Disubstituted-6-methylergolines and related compounds |
US3959288A (en) * | 1974-12-13 | 1976-05-25 | Eli Lilly And Company | 8-Oxymethylergolines and process therefor |
US4199579A (en) * | 1975-03-14 | 1980-04-22 | Siphar S. A. | Carbamates of 2-haloergolines and 2-haloergolenes and process for the preparation thereof |
DE2656344A1 (de) * | 1975-12-23 | 1977-07-07 | Sandoz Ag | Ergolinderivate, ihre verwendung und herstellung |
IT1192260B (it) * | 1977-07-05 | 1988-03-31 | Simes | Derivati di ergoline-2-tioeteri e loro solfossidi |
GB2056437A (en) * | 1979-08-07 | 1981-03-18 | Erba Farmitalia | Secoergoline derivatives |
US4382940A (en) * | 1979-12-06 | 1983-05-10 | Farmitalia Carlo Erba S.P.A. | Ercoline derivatives and therapeutic compositions having CNS affecting activity |
DE3403067A1 (de) * | 1984-01-30 | 1985-08-14 | Eckart Prof. Dr. 6500 Mainz Eich | Ergolin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
IT1213206B (it) * | 1984-08-07 | 1989-12-14 | Inverni Della Beffa Spa | Procedimento per la preparazione di derivati del lisergolo. |
GB8612366D0 (en) * | 1986-05-21 | 1986-06-25 | Erba Farmitalia | Ergoline esters |
AU7914587A (en) * | 1987-08-24 | 1989-03-31 | Molecular Control Corporation | Liquid crystal micelles, display, having concentric spheres |
-
1986
- 1986-06-25 GB GB868615471A patent/GB8615471D0/en active Pending
-
1987
- 1987-06-03 NZ NZ220543A patent/NZ220543A/xx unknown
- 1987-06-22 IL IL82946A patent/IL82946A/xx not_active IP Right Cessation
- 1987-06-22 FI FI872752A patent/FI85702C/fi not_active IP Right Cessation
- 1987-06-22 JP JP62155265A patent/JPH0745498B2/ja not_active Expired - Lifetime
- 1987-06-22 IE IE165287A patent/IE61319B1/en not_active IP Right Cessation
- 1987-06-23 PT PT85152A patent/PT85152B/pt not_active IP Right Cessation
- 1987-06-23 AU AU74632/87A patent/AU597672B2/en not_active Ceased
- 1987-06-23 US US07/065,597 patent/US4843073A/en not_active Expired - Fee Related
- 1987-06-23 CA CA000540338A patent/CA1339533C/en not_active Expired - Fee Related
- 1987-06-23 EP EP87305570A patent/EP0251652B1/en not_active Expired - Lifetime
- 1987-06-23 AT AT87305570T patent/ATE76407T1/de not_active IP Right Cessation
- 1987-06-23 DE DE8787305570T patent/DE3779190D1/de not_active Expired - Fee Related
- 1987-06-23 KR KR1019870006362A patent/KR950008970B1/ko not_active IP Right Cessation
- 1987-06-23 ES ES87305570T patent/ES2042567T3/es not_active Expired - Lifetime
- 1987-06-24 DK DK322587A patent/DK170099B1/da not_active IP Right Cessation
- 1987-06-24 SU SU874202786A patent/SU1547708A3/ru active
- 1987-06-24 ZA ZA874569A patent/ZA874569B/xx unknown
- 1987-06-24 HU HU872871A patent/HU196201B/hu not_active IP Right Cessation
-
1989
- 1989-03-24 US US07/328,518 patent/US5079364A/en not_active Expired - Fee Related
-
1992
- 1992-07-08 GR GR920401458T patent/GR3005115T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HU196201B (en) | 1988-10-28 |
IL82946A0 (en) | 1987-12-20 |
FI872752A (fi) | 1987-12-26 |
CA1339533C (en) | 1997-11-11 |
DK322587A (da) | 1987-12-26 |
IE871652L (en) | 1987-12-25 |
FI85702B (fi) | 1992-02-14 |
GR3005115T3 (ko) | 1993-05-24 |
PT85152A (en) | 1987-07-01 |
SU1547708A3 (ru) | 1990-02-28 |
NZ220543A (en) | 1989-06-28 |
JPH0745498B2 (ja) | 1995-05-17 |
FI85702C (fi) | 1992-05-25 |
DK322587D0 (da) | 1987-06-24 |
JPS6322577A (ja) | 1988-01-30 |
IL82946A (en) | 1991-04-15 |
PT85152B (pt) | 1990-03-30 |
HUT44543A (en) | 1988-03-28 |
DE3779190D1 (de) | 1992-06-25 |
AU597672B2 (en) | 1990-06-07 |
ZA874569B (en) | 1988-02-24 |
KR880000429A (ko) | 1988-03-25 |
ATE76407T1 (de) | 1992-06-15 |
AU7463287A (en) | 1988-01-07 |
US4843073A (en) | 1989-06-27 |
KR950008970B1 (ko) | 1995-08-10 |
ES2042567T3 (es) | 1993-12-16 |
EP0251652A3 (en) | 1989-04-05 |
US5079364A (en) | 1992-01-07 |
EP0251652A2 (en) | 1988-01-07 |
FI872752A0 (fi) | 1987-06-22 |
IE61319B1 (en) | 1994-11-02 |
EP0251652B1 (en) | 1992-05-20 |
GB8615471D0 (en) | 1986-07-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |