DK169609B1 - Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom - Google Patents

Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom Download PDF

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Publication number
DK169609B1
DK169609B1 DK275488A DK275488A DK169609B1 DK 169609 B1 DK169609 B1 DK 169609B1 DK 275488 A DK275488 A DK 275488A DK 275488 A DK275488 A DK 275488A DK 169609 B1 DK169609 B1 DK 169609B1
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DK
Denmark
Prior art keywords
compound
disease
treatment
parkinson
hydrogen
Prior art date
Application number
DK275488A
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Danish (da)
English (en)
Other versions
DK275488A (da
DK275488D0 (da
Inventor
David Andrew Arlwydd Owen
Original Assignee
Smith Kline French Lab
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Publication date
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Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of DK275488D0 publication Critical patent/DK275488D0/da
Publication of DK275488A publication Critical patent/DK275488A/da
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
DK275488A 1987-05-21 1988-05-19 Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom DK169609B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878712073A GB8712073D0 (en) 1987-05-21 1987-05-21 Medicament
GB8712073 1987-05-21

Publications (3)

Publication Number Publication Date
DK275488D0 DK275488D0 (da) 1988-05-19
DK275488A DK275488A (da) 1988-11-22
DK169609B1 true DK169609B1 (da) 1994-12-27

Family

ID=10617727

Family Applications (1)

Application Number Title Priority Date Filing Date
DK275488A DK169609B1 (da) 1987-05-21 1988-05-19 Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom

Country Status (21)

Country Link
US (2) US4824860A (hu)
EP (1) EP0299602B1 (hu)
JP (1) JPH062672B2 (hu)
AT (1) ATE83659T1 (hu)
AU (1) AU599792B2 (hu)
CA (1) CA1305421C (hu)
DE (1) DE3876877T2 (hu)
DK (1) DK169609B1 (hu)
ES (1) ES2052717T3 (hu)
GB (1) GB8712073D0 (hu)
GR (1) GR3007251T3 (hu)
HK (1) HK1000913A1 (hu)
HU (1) HU201871B (hu)
IE (1) IE63511B1 (hu)
LU (1) LU90098I2 (hu)
MX (1) MX9203543A (hu)
NL (1) NL970006I2 (hu)
NZ (1) NZ224709A (hu)
PH (1) PH23867A (hu)
PT (1) PT87542B (hu)
ZA (1) ZA883602B (hu)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008605D0 (en) * 1990-04-17 1990-06-13 Smith Kline French Lab Process
GB9015095D0 (en) * 1990-07-09 1990-08-29 Smith Kline French Lab Therapeutic method
AU4312593A (en) * 1992-05-18 1993-12-13 Smithkline Beecham Plc Use of indolone derivatives for the treatment of memory disorders, sexual dysfunction and Parkinson's disease
GB9300309D0 (en) * 1993-01-08 1993-03-03 Smithkline Beecham Plc Process
GB9511366D0 (en) * 1995-06-06 1995-08-02 Smithkline Beecham Plc Novel formulations
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
GB9612752D0 (en) * 1996-06-19 1996-08-21 Smithkline Beecham Plc Novel treatment
PT923551E (pt) * 1996-08-27 2002-09-30 American Home Prod Derivados de 4-aminoetoxi indolona
CA2327477A1 (en) * 1998-04-13 1999-10-21 James Albert Nelson 4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists
US6176242B1 (en) 1999-04-30 2001-01-23 Medtronic Inc Method of treating manic depression by brain infusion
US6218421B1 (en) * 1999-07-01 2001-04-17 Smithkline Beecham P.L.C. Method of promoting smoking cessation
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6277875B1 (en) * 2000-07-17 2001-08-21 Andrew J. Holman Use of dopamine D2/D3 receptor agonists to treat fibromyalgia
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
US7858602B2 (en) * 2000-10-16 2010-12-28 Rodriguez Victorio C Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging disorders due to oxidative stress and as growth factors of stem cells
US6871098B2 (en) * 2000-10-30 2005-03-22 Medtronic, Inc. Method for treating obsessive-compulsive disorder with electrical stimulation of the brain internal capsule
ES2285245T3 (es) * 2002-09-13 2007-11-16 Motac Neuroscience Limited Tratamiento de la disquinesia con 2,3-benzodiazapinas.
AU2003267557B2 (en) * 2002-09-17 2009-02-26 Motac Neuroscience Limited Treatment of dyskinesia
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
WO2005051488A1 (en) * 2003-11-26 2005-06-09 Pfizer Products Inc. Combination of dopamine agonists and monoamine reuptake inhibitors
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US7378439B2 (en) * 2004-01-20 2008-05-27 Usv, Ltd. Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride
US20050197385A1 (en) * 2004-02-20 2005-09-08 Schwarz Pharma Ag Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
WO2007048034A2 (en) * 2005-10-21 2007-04-26 Caritas St. Elizabeth Medical Center Of Boston, Inc. Use of androgens for the treatment of parkinson' s disease
US8475829B2 (en) * 2006-04-06 2013-07-02 Nupathe Inc. Implants for the treatment of dopamine associated states
WO2008001204A2 (en) * 2006-06-29 2008-01-03 Antares Pharma Ipl Ag Transdermal compositions of pramipexole having enhanced permeation properties
TW200815045A (en) * 2006-06-29 2008-04-01 Jazz Pharmaceuticals Inc Pharmaceutical compositions of ropinirole and methods of use thereof
US20090247537A1 (en) * 2008-03-25 2009-10-01 William Dale Overfield Methods for preventing or treating bruxism using dopaminergic agents
CN101574341B (zh) * 2008-05-05 2012-12-19 北京德众万全医药科技有限公司 一种罗匹尼罗的口服固体药物组合物
WO2010023693A2 (en) * 2008-09-01 2010-03-04 Lupin Limited Novel controlled release compositions of ropinirole
CA2738414C (en) 2008-09-29 2014-05-27 Wockhardt Research Centre Extended release dosage form of ropinirole
WO2010044108A2 (en) 2008-10-17 2010-04-22 Rubicon Research Private Limited Controlled release formulations of ropinirole
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
UA103851C2 (en) 2010-04-30 2013-11-25 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Propylaminoindan transdermal composition
WO2012129429A2 (en) 2011-03-24 2012-09-27 Teikoku Pharma Usa, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
JP5913614B2 (ja) 2011-11-09 2016-04-27 テイコク ファーマ ユーエスエー インコーポレーテッド 皮膚新生物の処置方法
WO2014070622A1 (en) 2012-11-02 2014-05-08 Teikoku Pharma Usa, Inc. Propynylaminoindan transdermal compositions
WO2015168616A1 (en) * 2014-05-02 2015-11-05 Abbvie Inc. Neuronal nicotinic agonists and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
US4588740A (en) * 1982-12-07 1986-05-13 Smithkline Beckman Corporation Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones

Also Published As

Publication number Publication date
HK1000913A1 (en) 1998-05-08
NL970006I1 (nl) 1997-04-01
MX9203543A (es) 1992-07-01
AU599792B2 (en) 1990-07-26
NL970006I2 (nl) 1997-10-01
EP0299602A2 (en) 1989-01-18
US4912126A (en) 1990-03-27
NZ224709A (en) 1997-02-24
HU201871B (en) 1991-01-28
HUT47217A (en) 1989-02-28
US4824860A (en) 1989-04-25
GR3007251T3 (hu) 1993-07-30
EP0299602A3 (en) 1990-06-06
PT87542B (pt) 1992-09-30
AU1644588A (en) 1988-11-24
PT87542A (pt) 1989-05-31
DK275488A (da) 1988-11-22
EP0299602B1 (en) 1992-12-23
LU90098I2 (fr) 1997-09-25
CA1305421C (en) 1992-07-21
IE63511B1 (en) 1995-05-03
GB8712073D0 (en) 1987-06-24
JPS63303966A (ja) 1988-12-12
ATE83659T1 (de) 1993-01-15
DE3876877T2 (de) 1993-04-29
JPH062672B2 (ja) 1994-01-12
DE3876877D1 (de) 1993-02-04
IE881469L (en) 1988-11-21
ES2052717T3 (es) 1994-07-16
ZA883602B (en) 1989-04-26
PH23867A (en) 1989-11-23
DK275488D0 (da) 1988-05-19

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1997 00011, 970131

CTFG Supplementary protection certificate (spc) issued

Free format text: CA 1997 00011, 970131, EXPIRES: 20110702

PUP Patent expired