DK1685131T3 - Hydroxyalkylsubstituerede pyrido-7-pyrimidin-7-oner - Google Patents
Hydroxyalkylsubstituerede pyrido-7-pyrimidin-7-onerInfo
- Publication number
- DK1685131T3 DK1685131T3 DK04797601T DK04797601T DK1685131T3 DK 1685131 T3 DK1685131 T3 DK 1685131T3 DK 04797601 T DK04797601 T DK 04797601T DK 04797601 T DK04797601 T DK 04797601T DK 1685131 T3 DK1685131 T3 DK 1685131T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrimidin
- hydroxyalkyl
- ones
- substituted pyrido
- pyrido
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51978903P | 2003-11-13 | 2003-11-13 | |
| PCT/EP2004/012475 WO2005047284A1 (en) | 2003-11-13 | 2004-11-04 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1685131T3 true DK1685131T3 (da) | 2007-07-09 |
Family
ID=34590444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04797601T DK1685131T3 (da) | 2003-11-13 | 2004-11-04 | Hydroxyalkylsubstituerede pyrido-7-pyrimidin-7-oner |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US7348331B2 (xx) |
| EP (1) | EP1685131B1 (xx) |
| JP (1) | JP4616839B2 (xx) |
| KR (1) | KR100816321B1 (xx) |
| CN (1) | CN100455582C (xx) |
| AR (1) | AR046705A1 (xx) |
| AT (1) | ATE356124T1 (xx) |
| AU (1) | AU2004289428B2 (xx) |
| BR (1) | BRPI0416030A (xx) |
| CA (1) | CA2544247A1 (xx) |
| CO (1) | CO5690600A2 (xx) |
| DE (1) | DE602004005238T2 (xx) |
| DK (1) | DK1685131T3 (xx) |
| ES (1) | ES2281843T3 (xx) |
| HK (1) | HK1099021A1 (xx) |
| HR (1) | HRP20070132T3 (xx) |
| IL (1) | IL175284A0 (xx) |
| MY (1) | MY141011A (xx) |
| NO (1) | NO20062256L (xx) |
| NZ (1) | NZ546634A (xx) |
| PL (1) | PL1685131T3 (xx) |
| PT (1) | PT1685131E (xx) |
| RU (1) | RU2348632C2 (xx) |
| SI (1) | SI1685131T1 (xx) |
| TW (1) | TWI349670B (xx) |
| WO (1) | WO2005047284A1 (xx) |
| ZA (1) | ZA200603829B (xx) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008011032A1 (en) | 2006-07-17 | 2008-01-24 | Amgen Inc. | Quinazoline and pyridopyrimidine derivatives as p38 kinase inhibitors |
| CN101568518A (zh) * | 2006-12-22 | 2009-10-28 | 霍夫曼-拉罗奇有限公司 | 用于氨基亚烷基二醇合成的化合物和方法 |
| JP2010529973A (ja) * | 2007-06-15 | 2010-09-02 | エフ．ホフマン−ラ ロシュ アーゲー | ３−アミノ−ペンタン−１，５−ジオールの新規製造方法 |
| WO2011075616A1 (en) * | 2009-12-18 | 2011-06-23 | Temple University - Of The Commonwealth System Of Higher Education | Substituted pyrido[2,3-d]pyrimidin-7(8h)-ones and therapeutic uses thereof |
| ES2689421T3 (es) | 2014-02-07 | 2018-11-14 | Principia Biopharma Inc. | Derivados de quinolina como inhibidores de los receptores de los factores de crecimiento de fibroblastos |
| CN107922410A (zh) | 2015-08-11 | 2018-04-17 | 普林斯匹亚生物制药公司 | 用于制备fgfr抑制剂的方法 |
| CN105418609B (zh) * | 2015-12-31 | 2017-06-23 | 山东大学 | 4‑(1,2,3‑三氮唑取代苯胺基)‑吡啶骈嘧啶酮衍生物及其制备方法与应用 |
| US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
| MY194619A (en) | 2016-06-02 | 2022-12-07 | Abbvie Inc | Glucocorticoid receptor agonist and immunoconjugates thereof |
| AU2017277478B2 (en) | 2016-06-08 | 2023-03-16 | Support-Venture Gmbh | Pharmaceutical combinations for treating cancer |
| JP2019528273A (ja) | 2016-08-17 | 2019-10-10 | サポート−ヴェンチャー ゲゼルシャフト ミット ベシュレンクター ハフトゥング | 聴力損失を予防又は治療する方法 |
| CN110636840A (zh) | 2017-04-04 | 2019-12-31 | 斯特里金股份公司 | 预防或治疗眼科疾病的方法 |
| US11479770B2 (en) | 2017-10-05 | 2022-10-25 | Fulcrum Therapeutics, Inc. | Use of p38 inhibitors to reduce expression of DUX4 |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| PT3658192T (pt) | 2017-12-01 | 2021-06-25 | Abbvie Inc | Agonista recetor de glucocorticóide e imunoconjugados do mesmo |
| BR112020023736A2 (pt) | 2018-05-21 | 2021-02-09 | Nerviano Medical Sciences, S.R.L. | compostos de piridonas heterocondensados e seu uso como inibidores de idh |
| KR20210031909A (ko) | 2018-07-13 | 2021-03-23 | 키나루스 아게 | 섬유증 질환을 예방 또는 치료하기 위한 ppar 효능제 및 p38 키나제 억제제의 조합물 |
| US20230000871A1 (en) | 2019-11-08 | 2023-01-05 | Nerviano Medical Sciences S.R.L. | Gem-disubstituted heterocyclic compounds and their use as idh inhibitors |
| US20230263803A1 (en) | 2020-08-11 | 2023-08-24 | Kinarus Ag | Methods of preventing or treating covid-19 and related viral diseases or disorders |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215216A (en) | 1979-04-18 | 1980-07-29 | American Home Products Corporation | 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives |
| US5037826A (en) | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
| EP0278686A1 (en) | 1987-02-07 | 1988-08-17 | The Wellcome Foundation Limited | Pyridopyrimidines methods for their preparation and pharmaceutical formulations thereof |
| WO1993017682A1 (en) | 1992-03-04 | 1993-09-16 | Abbott Laboratories | Angiotensin ii receptor antagonists |
| WO1996015128A2 (en) | 1994-11-14 | 1996-05-23 | Warner-Lambert Company | 6-ARYL PYRIDO[2,3-d]PYRIMIDINES AND NAPHTHYRIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION |
| IL115256A0 (en) | 1994-11-14 | 1995-12-31 | Warner Lambert Co | 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use |
| US5620981A (en) | 1995-05-03 | 1997-04-15 | Warner-Lambert Company | Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation |
| IL117923A (en) | 1995-05-03 | 2000-06-01 | Warner Lambert Co | Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds |
| ATE391719T1 (de) | 1997-02-05 | 2008-04-15 | Warner Lambert Co | Pyrido (2,3-d) pyrimidine und 4-amino-primidine als inhibitoren der zellulären proliferation |
| US5945422A (en) | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| IL139599A0 (en) | 1998-05-26 | 2002-02-10 | Warner Lambert Co | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
| US7053070B2 (en) | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| US20040224958A1 (en) | 2000-01-27 | 2004-11-11 | Booth Richard John | Pyridopyrimidinone derivatives for treatment of neurodegenerative disease |
| HUP0300136A2 (en) | 2000-03-06 | 2003-05-28 | Warner Lambert Co | 5-alkylpyrido [2,3-d]pyrimidines tyrosine kinase inhibitors, pharmaceutical compositions containing them and their use |
| US6518276B2 (en) | 2000-08-31 | 2003-02-11 | Syntex (U.S.A.) Llc | 7-oxo-pyridopyrimidines (II) |
| AU9378401A (en) * | 2000-08-31 | 2002-03-13 | Hoffmann La Roche | 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation |
| CZ20032416A3 (cs) * | 2001-02-12 | 2004-07-14 | F. Hoffmann-La Roche Ag | 6-Substituované pyridopyrimidiny |
| RS51044B (sr) * | 2002-01-22 | 2010-10-31 | Warner-Lambert Company Llc. | 2-(piridin-2-ilamino)-pirido(2,3-d)pirimidin-7-oni |
| FR2897336B1 (fr) | 2006-02-10 | 2010-07-30 | Ranger France | Support d'aile pour vehicule automobile |
-
2004
- 2004-11-04 PT PT04797601T patent/PT1685131E/pt unknown
- 2004-11-04 AT AT04797601T patent/ATE356124T1/de active
- 2004-11-04 WO PCT/EP2004/012475 patent/WO2005047284A1/en active IP Right Grant
- 2004-11-04 KR KR1020067009146A patent/KR100816321B1/ko not_active IP Right Cessation
- 2004-11-04 CA CA002544247A patent/CA2544247A1/en not_active Abandoned
- 2004-11-04 SI SI200430261T patent/SI1685131T1/sl unknown
- 2004-11-04 PL PL04797601T patent/PL1685131T3/pl unknown
- 2004-11-04 DK DK04797601T patent/DK1685131T3/da active
- 2004-11-04 RU RU2006120486/04A patent/RU2348632C2/ru not_active IP Right Cessation
- 2004-11-04 CN CNB2004800337221A patent/CN100455582C/zh not_active Expired - Fee Related
- 2004-11-04 JP JP2006538744A patent/JP4616839B2/ja not_active Expired - Fee Related
- 2004-11-04 AU AU2004289428A patent/AU2004289428B2/en not_active Ceased
- 2004-11-04 DE DE602004005238T patent/DE602004005238T2/de active Active
- 2004-11-04 ES ES04797601T patent/ES2281843T3/es active Active
- 2004-11-04 BR BRPI0416030-4A patent/BRPI0416030A/pt not_active IP Right Cessation
- 2004-11-04 NZ NZ546634A patent/NZ546634A/en not_active IP Right Cessation
- 2004-11-04 EP EP04797601A patent/EP1685131B1/en active Active
- 2004-11-09 MY MYPI20044668A patent/MY141011A/en unknown
- 2004-11-10 AR ARP040104138A patent/AR046705A1/es not_active Application Discontinuation
- 2004-11-10 TW TW093134375A patent/TWI349670B/zh not_active IP Right Cessation
- 2004-11-12 US US10/987,656 patent/US7348331B2/en not_active Expired - Fee Related
-
2006
- 2006-04-27 IL IL175284A patent/IL175284A0/en unknown
- 2006-05-12 ZA ZA200603829A patent/ZA200603829B/en unknown
- 2006-05-12 CO CO06045585A patent/CO5690600A2/es not_active Application Discontinuation
- 2006-05-19 NO NO20062256A patent/NO20062256L/no not_active Application Discontinuation
-
2007
- 2007-03-30 HR HR20070132T patent/HRP20070132T3/xx unknown
- 2007-06-18 HK HK07106518.3A patent/HK1099021A1/xx not_active IP Right Cessation
- 2007-11-19 US US11/985,821 patent/US7750016B2/en not_active Expired - Fee Related
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