AU9378401A - 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation - Google Patents

7-oxo pyridopyrimidines as inhibitors of a cellular proliferation

Info

Publication number
AU9378401A
AU9378401A AU9378401A AU9378401A AU9378401A AU 9378401 A AU9378401 A AU 9378401A AU 9378401 A AU9378401 A AU 9378401A AU 9378401 A AU9378401 A AU 9378401A AU 9378401 A AU9378401 A AU 9378401A
Authority
AU
Australia
Prior art keywords
inhibitors
cellular proliferation
pyridopyrimidines
oxo
oxo pyridopyrimidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU9378401A
Inventor
Jian Jeffrey Chen
James Patrick Dunn
David Michael Goldstein
Julie Anne Lim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU9378401A publication Critical patent/AU9378401A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AU9378401A 2000-08-31 2001-08-22 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation Pending AU9378401A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22958400P 2000-08-31 2000-08-31
PCT/EP2001/009689 WO2002018380A1 (en) 2000-08-31 2001-08-22 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation

Publications (1)

Publication Number Publication Date
AU9378401A true AU9378401A (en) 2002-03-13

Family

ID=22861859

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001293784A Ceased AU2001293784B2 (en) 2000-08-31 2001-08-22 7-OXO pyridopyrimidines as inhibitors of a cellular proliferation
AU9378401A Pending AU9378401A (en) 2000-08-31 2001-08-22 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU2001293784A Ceased AU2001293784B2 (en) 2000-08-31 2001-08-22 7-OXO pyridopyrimidines as inhibitors of a cellular proliferation

Country Status (15)

Country Link
EP (1) EP1315726A1 (en)
JP (1) JP4141830B2 (en)
KR (1) KR100571339B1 (en)
CN (1) CN1275964C (en)
AR (1) AR033681A1 (en)
AU (2) AU2001293784B2 (en)
BR (1) BR0113628A (en)
CA (1) CA2420286A1 (en)
GT (1) GT200100191A (en)
MX (1) MXPA03001821A (en)
PA (1) PA8527301A1 (en)
PE (1) PE20020406A1 (en)
UY (1) UY26918A1 (en)
WO (1) WO2002018380A1 (en)
ZA (1) ZA200301079B (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518276B2 (en) 2000-08-31 2003-02-11 Syntex (U.S.A.) Llc 7-oxo-pyridopyrimidines (II)
WO2002018379A2 (en) * 2000-08-31 2002-03-07 F. Hoffmann-La Roche Ag 7-oxo pyridopyrimidines
PL374544A1 (en) * 2002-04-03 2005-10-31 F.Hoffmann-La Roche Ag Imidazo fused compounds
ATE370952T1 (en) * 2002-04-19 2007-09-15 Smithkline Beecham Corp NEW CONNECTIONS
US7084270B2 (en) 2002-08-14 2006-08-01 Hoffman-La Roche Inc. Pyrimido compounds having antiproliferative activity
UY27939A1 (en) 2002-08-21 2004-03-31 Glaxo Group Ltd COMPOUNDS
US7112676B2 (en) 2002-11-04 2006-09-26 Hoffmann-La Roche Inc. Pyrimido compounds having antiproliferative activity
MXPA05005028A (en) 2002-11-18 2005-08-03 Hoffmann La Roche Diazinopyrimidines.
US7098332B2 (en) 2002-12-20 2006-08-29 Hoffmann-La Roche Inc. 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones
MXPA05010765A (en) 2003-04-10 2005-12-12 Hoffmann La Roche Pyrimido compounds.
CA2539190A1 (en) * 2003-07-07 2005-01-27 George F. Vande Woude Inhibition of tumor angiogenesis by combination of thrombospondin-1 and inhibitors of vascular endothelial growth factor
ES2281843T3 (en) * 2003-11-13 2007-10-01 F. Hoffmann-La Roche Ag PIRIDO-7-PIRIMIDIN-7-WAVES REPLACED WITH HYDROXIALQUIL.
WO2005105097A2 (en) * 2004-04-28 2005-11-10 Gpc Biotech Ag Pyridopyrimidines for treating inflammatory and other diseases
US20070054916A1 (en) * 2004-10-01 2007-03-08 Amgen Inc. Aryl nitrogen-containing bicyclic compounds and methods of use
WO2006056863A1 (en) * 2004-11-23 2006-06-01 Ranbaxy Laboratories Limited Pyrido’2, 3-d!pyrimidines as anti-inflammatory agents
WO2006082492A1 (en) * 2005-02-02 2006-08-10 Ranbaxy Laboratories Limited Azabicyclo derivatives as anti-inflammatory agents
WO2007036791A1 (en) * 2005-09-28 2007-04-05 Ranbaxy Laboratories Limited Pyrido-pyridimidine derivatives useful as antiinflammatory agents
BRPI0706781A2 (en) 2006-01-31 2011-04-05 Hoffmann La Roche 7h-pyrido [3,4-d] pyrimidin-8-ones, their manufacture and use as protein kinase inhibitors
KR100661523B1 (en) * 2006-06-09 2006-12-26 주식회사 청용산기 Box correcting device of stitching progress for carton box erecting
EP1914234A1 (en) 2006-10-16 2008-04-23 GPC Biotech Inc. Pyrido[2,3-d]pyrimidines and their use as kinase inhibitors
CA2668731A1 (en) 2006-11-09 2008-05-15 Tobias Gabriel Kinase inhibitors and methods for using the same
WO2008078249A1 (en) * 2006-12-21 2008-07-03 Ranbaxy Laboratories Limited Anti-inflammatory agents
EP2112150B1 (en) 2008-04-22 2013-10-16 Forma Therapeutics, Inc. Improved raf inhibitors
KR101106162B1 (en) * 2010-04-20 2012-01-20 주식회사 청용산기 Stitching device for packing box making apparatus
CN104428298B (en) * 2012-03-22 2017-03-01 奥斯克技术有限公司 The Pyridopyrimidine compound replacing and its purposes as FLT3 inhibitor
KR102350704B1 (en) 2013-03-15 2022-01-13 셀젠 카르 엘엘씨 Heteroaryl compounds and uses thereof
US9321786B2 (en) 2013-03-15 2016-04-26 Celgene Avilomics Research, Inc. Heteroaryl compounds and uses thereof
MA38393B1 (en) 2014-03-13 2018-11-30 Sanofi Sa Heteroaryl Compounds and Related Uses
WO2016037255A2 (en) 2014-09-12 2016-03-17 Biolab Sanus Farmacêutica Ltda. New pyridopyrimidines derivatives compounds
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
MX2020003594A (en) 2017-10-05 2021-04-07 Fulcrum Therapeutics Inc P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd.
WO2020142612A1 (en) * 2019-01-03 2020-07-09 Genentech, Inc. Pyrido-pyrimidinone and pteridinone compounds as inhibitors of endoribonuclease inositol requiring enzyme i (ire i alpha) for the treatment of cancer diseases.
MA56050A (en) * 2019-05-31 2022-04-06 Servier Lab HETEROBICYCLIC MAT2A INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF CANCER
WO2022052924A1 (en) * 2020-09-11 2022-03-17 上海凌达生物医药有限公司 Preparation method for class of nitrogen-containing fused ring compounds and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU711426B2 (en) * 1994-11-14 1999-10-14 Warner-Lambert Company 6-aryl pyrido(2,3-d)pyrimidines and naphthyridines for inhibiting protein tyrosine kinase mediated cellular proliferation
IL117923A (en) * 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
ES2310039T3 (en) * 1998-05-26 2008-12-16 Warner-Lambert Company Llc BICYCLE PYRIMIDINES AND BICYCLE 3,4-DIHYDROPIRIMIDINS AS INHIBITORS OF CELL PROLIFERATION.

Also Published As

Publication number Publication date
GT200100191A (en) 2002-05-16
AR033681A1 (en) 2004-01-07
BR0113628A (en) 2003-07-01
MXPA03001821A (en) 2003-06-04
JP4141830B2 (en) 2008-08-27
KR100571339B1 (en) 2006-04-17
PA8527301A1 (en) 2002-07-30
CN1275964C (en) 2006-09-20
EP1315726A1 (en) 2003-06-04
CA2420286A1 (en) 2002-03-07
PE20020406A1 (en) 2002-05-17
ZA200301079B (en) 2004-05-07
AU2001293784B2 (en) 2007-08-30
JP2004507541A (en) 2004-03-11
UY26918A1 (en) 2002-02-28
KR20030022422A (en) 2003-03-15
CN1451005A (en) 2003-10-22
WO2002018380A1 (en) 2002-03-07

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