DK168388B1 - Forbindelser i antibiotikumkompleks LL-E33288, lægemidler indeholdende disse forbindelser og mikroorganismekultur til brug ved deres fremstilling - Google Patents

Forbindelser i antibiotikumkompleks LL-E33288, lægemidler indeholdende disse forbindelser og mikroorganismekultur til brug ved deres fremstilling Download PDF

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Publication number
DK168388B1
DK168388B1 DK529685A DK529685A DK168388B1 DK 168388 B1 DK168388 B1 DK 168388B1 DK 529685 A DK529685 A DK 529685A DK 529685 A DK529685 A DK 529685A DK 168388 B1 DK168388 B1 DK 168388B1
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Prior art keywords
ethyl acetate
dihydrogen phosphate
potassium dihydrogen
aqueous potassium
molar aqueous
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DK529685A
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Danish (da)
English (en)
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DK529685D0 (da
DK529685A (da
Inventor
May Dean-Ming Lee
Michael Greenstein
David Paul Labeda
Amedeo Alexander Fantini
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American Cyanamid Co
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Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DK529685D0 publication Critical patent/DK529685D0/da
Publication of DK529685A publication Critical patent/DK529685A/da
Application granted granted Critical
Publication of DK168388B1 publication Critical patent/DK168388B1/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29Micromonospora

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
DK529685A 1984-11-16 1985-11-15 Forbindelser i antibiotikumkompleks LL-E33288, lægemidler indeholdende disse forbindelser og mikroorganismekultur til brug ved deres fremstilling DK168388B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67203184A 1984-11-16 1984-11-16
US67203184 1984-11-16
US78706685A 1985-10-17 1985-10-17
US78706685 1985-10-17

Publications (3)

Publication Number Publication Date
DK529685D0 DK529685D0 (da) 1985-11-15
DK529685A DK529685A (da) 1986-05-17
DK168388B1 true DK168388B1 (da) 1994-03-21

Family

ID=27100668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK529685A DK168388B1 (da) 1984-11-16 1985-11-15 Forbindelser i antibiotikumkompleks LL-E33288, lægemidler indeholdende disse forbindelser og mikroorganismekultur til brug ved deres fremstilling

Country Status (20)

Country Link
EP (1) EP0182152B1 (fr)
JP (1) JPH0774228B2 (fr)
KR (1) KR890001289B1 (fr)
AT (1) ATE180513T1 (fr)
AU (1) AU589918B2 (fr)
CA (1) CA1291054C (fr)
DE (1) DE3588213T2 (fr)
DK (1) DK168388B1 (fr)
EG (1) EG17709A (fr)
ES (1) ES8703160A1 (fr)
FI (1) FI86892C (fr)
GR (1) GR852725B (fr)
HK (1) HK1011385A1 (fr)
HU (1) HU195855B (fr)
IL (7) IL76878A (fr)
LV (1) LV12523B (fr)
MX (1) MX9203146A (fr)
NO (1) NO163574C (fr)
NZ (1) NZ214114A (fr)
PT (1) PT81493B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3440423A1 (de) * 1984-11-06 1986-05-07 Dr. Karl Thomae Gmbh, 7950 Biberach Antibiotisches polypeptid, verfahren zu seiner herstellung, dieses polypeptid erzeugender stamm von staphylococcus epidermidis, dieses polypeptid enthaltende zubereitungsformen und seine verwendung zur bekaempfung infektioeser erkrankungen
US5024948A (en) * 1985-10-17 1991-06-18 American Cyanamid Company Genetic system for micromonospora
SG52432A1 (en) * 1987-01-30 1998-09-28 American Cyanamid Co Antitumor antibiotics (pseudoaglycone and dihydro derivatives of ll-33228 complex)
US4980297A (en) * 1987-02-27 1990-12-25 Becton, Dickinson And Company Device for the membrane separation of the components of a liquid sample
EP0313874B1 (fr) * 1987-10-30 1994-04-13 American Cyanamid Company Analogues disulfuriques des agents antitumoraux LL-E33288
EP0330874A3 (fr) * 1988-02-29 1989-10-18 American Cyanamid Company Agents antibactériens et antitumoraux LL-E33288 epsilon-I et LL-E33288-epsilon-Br, avec les procédés et intermédiaires pour obtention desdits agents
US4977143A (en) * 1988-02-29 1990-12-11 American Cyanamid Company Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
US4978748A (en) * 1988-02-29 1990-12-18 American Cyanamid Company Intermediate and process for producing the antibacterial and antitumor agents LL-E33288ε-I and LL-E33288Epsilon-Br
EP0342341A3 (fr) * 1988-05-17 1991-07-24 American Cyanamid Company Méthode pour la fabrication de l'antibiotique antitumoral LL-E33288 Gamma 2
IL94540A0 (en) * 1989-06-29 1991-03-10 American Cyanamid Co Antibiotic ll-e19085
CN109553646A (zh) * 2019-01-21 2019-04-02 浙江海正药业股份有限公司 一种纯化卡里奇霉素的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU515150B2 (en) * 1975-02-18 1981-03-19 Sterling Drug Inc. Preparation of aminocyclitol antibiotics
US4692333A (en) * 1982-08-26 1987-09-08 Gruppo Lepetit S.P.A. Antimicrobial and antitumor antibiotic M 9026 and its pure individual factors 1, 2, and 3 and microbial process for production thereof
JPS6024195A (ja) * 1983-07-18 1985-02-06 Kyowa Hakko Kogyo Co Ltd サイコフラニンの製造法
US4843008A (en) * 1984-12-24 1989-06-27 Yamanouchi Pharmaceutical Co., Ltd. Novel microorganisms and a novel process for producing antibiotics

Also Published As

Publication number Publication date
EP0182152A3 (fr) 1987-08-05
FI86892B (fi) 1992-07-15
NO163574C (no) 1990-06-20
JPS61158928A (ja) 1986-07-18
FI854510A (fi) 1986-05-17
JPH0774228B2 (ja) 1995-08-09
NZ214114A (en) 1989-04-26
IL76878A (en) 1991-12-15
IL93419A0 (en) 1990-11-29
CA1291054C (fr) 1991-10-22
IL93417A0 (en) 1990-11-29
IL93418A0 (en) 1990-11-29
AU589918B2 (en) 1989-10-26
KR870004144A (ko) 1987-05-07
FI86892C (fi) 1992-10-26
IL76878A0 (en) 1986-02-28
EP0182152B1 (fr) 1999-05-26
IL93416A0 (en) 1990-11-29
ES548953A0 (es) 1987-02-16
ES8703160A1 (es) 1987-02-16
HU195855B (en) 1988-07-28
IL93421A0 (en) 1990-11-29
DK529685D0 (da) 1985-11-15
PT81493B (pt) 1987-11-11
DE3588213T2 (de) 1999-09-30
AU4995785A (en) 1986-05-22
EG17709A (en) 1990-08-30
HUT41839A (en) 1987-05-28
LV12523A (en) 2000-08-20
NO163574B (no) 1990-03-12
ATE180513T1 (de) 1999-06-15
EP0182152A2 (fr) 1986-05-28
LV12523B (en) 2000-11-20
FI854510A0 (fi) 1985-11-15
DE3588213D1 (de) 1999-07-01
HK1011385A1 (en) 1999-07-09
PT81493A (en) 1985-12-01
NO854578L (no) 1986-05-20
IL93420A0 (en) 1990-11-29
DK529685A (da) 1986-05-17
GR852725B (fr) 1986-03-19
KR890001289B1 (ko) 1989-04-28
MX9203146A (es) 1992-07-01

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