IL93418A0 - Antitumor antibiotics(ll-e33288 complex) - Google Patents
Antitumor antibiotics(ll-e33288 complex)Info
- Publication number
- IL93418A0 IL93418A0 IL93418A IL9341890A IL93418A0 IL 93418 A0 IL93418 A0 IL 93418A0 IL 93418 A IL93418 A IL 93418A IL 9341890 A IL9341890 A IL 9341890A IL 93418 A0 IL93418 A0 IL 93418A0
- Authority
- IL
- Israel
- Prior art keywords
- complex
- antitumor antibiotics
- nrrl
- micromonospora
- calichensis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/29—Micromonospora
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Hydrogenated Pyridines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Antibacterial and antitumor agents designated LL-E33288 complex and their production by new strains of Micromonospora, Micromonospora echinospora ssp. calichensis, NRRL-15839 and NRRL-15975, are disclosed.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL93418A IL93418A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67203184A | 1984-11-16 | 1984-11-16 | |
US78706685A | 1985-10-17 | 1985-10-17 | |
IL76878A IL76878A (en) | 1984-11-16 | 1985-10-29 | Antitumor antibiotic ll-33288alpha-br complex and process for its preparation |
IL93418A IL93418A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
Publications (1)
Publication Number | Publication Date |
---|---|
IL93418A0 true IL93418A0 (en) | 1990-11-29 |
Family
ID=27100668
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL76878A IL76878A (en) | 1984-11-16 | 1985-10-29 | Antitumor antibiotic ll-33288alpha-br complex and process for its preparation |
IL93419A IL93419A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93420A IL93420A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93421A IL93421A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93417A IL93417A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93418A IL93418A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93416A IL93416A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
Family Applications Before (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL76878A IL76878A (en) | 1984-11-16 | 1985-10-29 | Antitumor antibiotic ll-33288alpha-br complex and process for its preparation |
IL93419A IL93419A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93420A IL93420A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93421A IL93421A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
IL93417A IL93417A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL93416A IL93416A0 (en) | 1984-11-16 | 1990-02-16 | Antitumor antibiotics(ll-e33288 complex) |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0182152B1 (en) |
JP (1) | JPH0774228B2 (en) |
KR (1) | KR890001289B1 (en) |
AT (1) | ATE180513T1 (en) |
AU (1) | AU589918B2 (en) |
CA (1) | CA1291054C (en) |
DE (1) | DE3588213T2 (en) |
DK (1) | DK168388B1 (en) |
EG (1) | EG17709A (en) |
ES (1) | ES8703160A1 (en) |
FI (1) | FI86892C (en) |
GR (1) | GR852725B (en) |
HK (1) | HK1011385A1 (en) |
HU (1) | HU195855B (en) |
IL (7) | IL76878A (en) |
LV (1) | LV12523B (en) |
MX (1) | MX9203146A (en) |
NO (1) | NO163574C (en) |
NZ (1) | NZ214114A (en) |
PT (1) | PT81493B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3440423A1 (en) * | 1984-11-06 | 1986-05-07 | Dr. Karl Thomae Gmbh, 7950 Biberach | Antibiotic polypeptide, process for its preparation, strain of Staphylococcus epidermidis producing this polypeptide, preparation forms containing this polypeptide and its use for the control of infectious diseases |
US5024948A (en) * | 1985-10-17 | 1991-06-18 | American Cyanamid Company | Genetic system for micromonospora |
EP0276485B1 (en) * | 1987-01-30 | 2002-06-12 | American Cyanamid Company | Dihydro derivatives of LL-E33288 antibiotics |
US4980297A (en) * | 1987-02-27 | 1990-12-25 | Becton, Dickinson And Company | Device for the membrane separation of the components of a liquid sample |
ES2059464T3 (en) * | 1987-10-30 | 1994-11-16 | American Cyanamid Co | SPECIFICALLY DIRECTED FORMS OF ANTI-TUMORAL AGENTS OF METHYLTRITIO. |
US4977143A (en) * | 1988-02-29 | 1990-12-11 | American Cyanamid Company | Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR |
US4996305A (en) * | 1988-02-29 | 1991-02-26 | American Cyanamid Company | Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br |
EP0330874A3 (en) * | 1988-02-29 | 1989-10-18 | American Cyanamid Company | Antibacterial and antitumor agents LL-E33288 epsilon-I and LL-E33288-epsilonBr, with processes and intermediates for producing said agents |
US4978748A (en) * | 1988-02-29 | 1990-12-18 | American Cyanamid Company | Intermediate and process for producing the antibacterial and antitumor agents LL-E33288ε-I and LL-E33288Epsilon-Br |
EP0342341A3 (en) * | 1988-05-17 | 1991-07-24 | American Cyanamid Company | Process for producing antitumor antibiotic ll-e33288gamma2 |
EP0405151A1 (en) * | 1989-06-29 | 1991-01-02 | American Cyanamid Company | Antibiotic LL-E19085 |
CN109553646A (en) * | 2019-01-21 | 2019-04-02 | 浙江海正药业股份有限公司 | A kind of preparation method purifying Calicheamicin |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU515150B2 (en) * | 1975-02-18 | 1981-03-19 | Sterling Drug Inc. | Preparation of aminocyclitol antibiotics |
US4692333A (en) * | 1982-08-26 | 1987-09-08 | Gruppo Lepetit S.P.A. | Antimicrobial and antitumor antibiotic M 9026 and its pure individual factors 1, 2, and 3 and microbial process for production thereof |
JPS6024195A (en) * | 1983-07-18 | 1985-02-06 | Kyowa Hakko Kogyo Co Ltd | Production of psicofuranine |
US4843008A (en) * | 1984-12-24 | 1989-06-27 | Yamanouchi Pharmaceutical Co., Ltd. | Novel microorganisms and a novel process for producing antibiotics |
-
1985
- 1985-10-29 AT AT85113751T patent/ATE180513T1/en not_active IP Right Cessation
- 1985-10-29 EP EP85113751A patent/EP0182152B1/en not_active Expired - Lifetime
- 1985-10-29 DE DE3588213T patent/DE3588213T2/en not_active Expired - Lifetime
- 1985-10-29 IL IL76878A patent/IL76878A/en not_active IP Right Cessation
- 1985-11-08 NZ NZ214114A patent/NZ214114A/en unknown
- 1985-11-11 GR GR852725A patent/GR852725B/el unknown
- 1985-11-14 PT PT81493A patent/PT81493B/en unknown
- 1985-11-14 CA CA000495303A patent/CA1291054C/en not_active Expired - Lifetime
- 1985-11-15 ES ES548953A patent/ES8703160A1/en not_active Expired
- 1985-11-15 NO NO854578A patent/NO163574C/en not_active IP Right Cessation
- 1985-11-15 DK DK529685A patent/DK168388B1/en not_active IP Right Cessation
- 1985-11-15 HU HU854365A patent/HU195855B/en unknown
- 1985-11-15 KR KR1019850008548A patent/KR890001289B1/en not_active IP Right Cessation
- 1985-11-15 JP JP60255157A patent/JPH0774228B2/en not_active Expired - Lifetime
- 1985-11-15 AU AU49957/85A patent/AU589918B2/en not_active Expired
- 1985-11-15 FI FI854510A patent/FI86892C/en not_active IP Right Cessation
- 1985-11-17 EG EG731/85A patent/EG17709A/en active
-
1990
- 1990-02-16 IL IL93419A patent/IL93419A0/en unknown
- 1990-02-16 IL IL93420A patent/IL93420A0/en unknown
- 1990-02-16 IL IL93421A patent/IL93421A0/en unknown
- 1990-02-16 IL IL93417A patent/IL93417A0/en unknown
- 1990-02-16 IL IL93418A patent/IL93418A0/en unknown
- 1990-02-16 IL IL93416A patent/IL93416A0/en unknown
-
1992
- 1992-06-23 MX MX9203146A patent/MX9203146A/en unknown
-
1998
- 1998-11-24 HK HK98112285A patent/HK1011385A1/en not_active IP Right Cessation
-
2000
- 2000-05-19 LV LVP-00-64A patent/LV12523B/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1011385A1 (en) | Antitumor antibiotics (LL-E33288 complex) | |
SG52432A1 (en) | Antitumor antibiotics (pseudoaglycone and dihydro derivatives of ll-33228 complex) | |
AU581886B2 (en) | CL-1724 antibiotic/antitumor compounds, their production and use | |
JPS5799200A (en) | Production of acranomycins | |
ES8502729A1 (en) | Antimicrobial and antitumor antibiotic M 9026 and its pure individual factors 1, 2 and 3. | |
EP0330874A3 (en) | Antibacterial and antitumor agents LL-E33288 epsilon-I and LL-E33288-epsilonBr, with processes and intermediates for producing said agents | |
ES8306388A1 (en) | Antibiotic LL BO1208 alpha and LL BO1208 beta. | |
SG64329A1 (en) | Antitumor antibiotics (LL-E33288 complex) | |
NZ224004A (en) | Production of ll-e33288 antibiotics by fermentation of micromonospora echinospora sp | |
ES8506043A1 (en) | Improvements in or relating to macrolide antibiotics. | |
IL93417A (en) | Antitumor antibiotics ll-e33288 ypsilon1-br | |
UA18246A (en) | Method of 4-deoxy-13(s)-dihydro-4-iodofuricine production | |
JPS57132887A (en) | Antibiotic s/433 |