DK167904B1 - Farmaceutisk praeparat indeholdende en kombination af angiotensin-converting-enzyme-inhibitorer calciumantagonister samt fremgangsmaade til fremstilling af praeparatet - Google Patents

Farmaceutisk praeparat indeholdende en kombination af angiotensin-converting-enzyme-inhibitorer calciumantagonister samt fremgangsmaade til fremstilling af praeparatet Download PDF

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Publication number
DK167904B1
DK167904B1 DK516487A DK516487A DK167904B1 DK 167904 B1 DK167904 B1 DK 167904B1 DK 516487 A DK516487 A DK 516487A DK 516487 A DK516487 A DK 516487A DK 167904 B1 DK167904 B1 DK 167904B1
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DK
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Prior art keywords
alkyl
physiologically acceptable
aryl
preparation
amino
Prior art date
Application number
DK516487A
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Danish (da)
English (en)
Other versions
DK516487A (da
DK516487D0 (da
Inventor
Reinhard Becker
Rainer Henning
Wolfgang Rueger
Volker Teetz
Hansjoerg Urbach
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36747182&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK167904(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK516487D0 publication Critical patent/DK516487D0/da
Publication of DK516487A publication Critical patent/DK516487A/da
Application granted granted Critical
Publication of DK167904B1 publication Critical patent/DK167904B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK516487A 1986-10-02 1987-10-01 Farmaceutisk praeparat indeholdende en kombination af angiotensin-converting-enzyme-inhibitorer calciumantagonister samt fremgangsmaade til fremstilling af praeparatet DK167904B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3633496 1986-10-02
DE19863633496 DE3633496A1 (de) 1986-10-02 1986-10-02 Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
AT260087 1987-10-08
AT0260087A AT402894B (de) 1986-10-02 1987-10-08 Kombination von angiotensin-converting-enzyme- hemmern mit calciumantagonisten sowie ein erzeugnis, das diese enthält, zur anwendung bei der behandlung des bluthochdrucks

Publications (3)

Publication Number Publication Date
DK516487D0 DK516487D0 (da) 1987-10-01
DK516487A DK516487A (da) 1988-04-03
DK167904B1 true DK167904B1 (da) 1994-01-03

Family

ID=36747182

Family Applications (1)

Application Number Title Priority Date Filing Date
DK516487A DK167904B1 (da) 1986-10-02 1987-10-01 Farmaceutisk praeparat indeholdende en kombination af angiotensin-converting-enzyme-inhibitorer calciumantagonister samt fremgangsmaade til fremstilling af praeparatet

Country Status (26)

Country Link
US (3) US5098910A (xx)
EP (1) EP0265685B1 (xx)
JP (2) JP2752043B2 (xx)
KR (1) KR970005838B1 (xx)
AR (1) AR243083A1 (xx)
AT (2) ATE78697T1 (xx)
AU (1) AU611863B2 (xx)
CA (1) CA1317545C (xx)
DD (1) DD272035A5 (xx)
DE (3) DE3633496A1 (xx)
DK (1) DK167904B1 (xx)
EG (1) EG18081A (xx)
ES (1) ES2043626T3 (xx)
FI (1) FI874281A (xx)
GR (1) GR3006042T3 (xx)
HU (1) HU199302B (xx)
IE (1) IE59975B1 (xx)
IL (1) IL84054A (xx)
LU (1) LU90345I2 (xx)
MA (1) MA21072A1 (xx)
MX (1) MX8639A (xx)
NL (1) NL980030I2 (xx)
NO (2) NO175621C (xx)
NZ (1) NZ221989A (xx)
PT (1) PT85843B (xx)
ZA (1) ZA877385B (xx)

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US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
HU199681B (en) * 1986-11-03 1990-03-28 Sandoz Ag Process for producing new pharmaceutical composition against hypertension and atonic cardiac decomposition
FR2607004B1 (fr) * 1986-11-20 1990-06-01 Synthelabo Compositions pharmaceutiques contenant du diltiazem et un inhibiteur de l'enzyme de conversion de l'angiotensine
USH734H (en) * 1988-03-07 1990-02-06 E. R. Squibb & Sons, Inc. Method for inhibiting onset of or treating migraine headaches employing an ACE inhibitor
JPH01275529A (ja) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc 晩発性運動障害の抑制治療剤
DE3818245A1 (de) * 1988-05-28 1989-12-07 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
EP0391462A1 (en) * 1989-04-05 1990-10-10 Janssen Pharmaceutica N.V. Synergistic compositions containing ketanserin
TW197945B (xx) * 1990-11-27 1993-01-11 Hoechst Ag
DE4109134A1 (de) * 1991-03-20 1992-09-24 Knoll Ag Erzeugnisse, enthaltend verapamil und trandolapril
US6162802A (en) * 1992-03-10 2000-12-19 Papa; Joseph Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
DE4314962A1 (de) * 1993-05-06 1994-11-10 Bayer Ag Substituierte Piperazine
JP3057471B2 (ja) 1993-06-07 2000-06-26 武田薬品工業株式会社 アンジオテンシンｉｉ介在性諸疾患の予防または治療剤
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US5658832A (en) * 1994-10-17 1997-08-19 Regents Of The University Of California Method of forming a spacer for field emission flat panel displays
PT804229E (pt) * 1995-03-16 2003-06-30 Pfizer Utilizacao de amlodipina de um dos seus sais ou defelodipina em combinacao com um inibidor da en zima de conversao da angiotensina (ace) para no fabrico de um medicamento destinado ao tratamento da insuficiencia cardiaca congestiva nao isquemica
FR2733911B1 (fr) * 1995-05-09 1998-05-29 Takeda Chemical Industries Ltd Composition pharmaceutique pour maladies renales ou cardio-vasculaires
EP0795327A1 (en) * 1996-03-13 1997-09-17 Pfizer Inc. Use of Amlodipine for the treatment and prophylaxis of congestive cardiac failure of non-ischaemic origin
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CA2382549C (en) * 1999-08-30 2005-03-15 Aventis Pharma Deutschland Gmbh Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
US20040005359A1 (en) * 2002-06-27 2004-01-08 Cheng Xiu Xiu Controlled release oral dosage form
US20050101640A1 (en) * 2002-10-16 2005-05-12 Recordati Ireland Limited Lisinopril/lercanidipine combination therapy
US20040147566A1 (en) * 2002-10-16 2004-07-29 Amedeo Leonardi Lisinopril/lercanidipine combination therapy
US20050032784A1 (en) * 2003-04-01 2005-02-10 University Of Florida Research Foundation, Inc. Combination drug therapy for treating hypertension
KR100546710B1 (ko) 2003-07-02 2006-01-26 엘지.필립스 엘시디 주식회사 액정표시장치의 아날로그 버퍼회로
CA2586547A1 (en) * 2004-11-05 2006-05-11 King Pharmaceuticals Research & Development, Inc. Stabilized individually coated ramipril particles, compositions and methods
GB0624087D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril combination salt
GB0624090D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amine salts
GB0624084D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amino acid salts
WO2009125944A2 (ko) * 2008-04-10 2009-10-15 한올제약주식회사 비디히드로피리딘계 칼슘 채널 차단제 및 안지오텐신-2 수용체 차단제를 포함하는 약제학적 제제
CA2790817A1 (en) 2010-02-24 2011-09-01 Sanofi-Aventis Deutschland Gmbh Solid pharmaceutical formulations of ramipril and amlodipine besylate, and their preparation
RU2543637C2 (ru) * 2012-12-06 2015-03-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здавоохранения Российской Федерации Пролонгированная фармацевтическая композиция гипотензивного действия и способ ее изготовления

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Also Published As

Publication number Publication date
ZA877385B (en) 1988-05-25
ES2043626T3 (es) 1994-01-01
US5721244A (en) 1998-02-24
DE19975008I2 (de) 2004-07-01
JP2752043B2 (ja) 1998-05-18
DK516487A (da) 1988-04-03
IL84054A (en) 1993-01-31
NO175621C (no) 1994-11-09
CA1317545C (en) 1993-05-11
DE3633496A1 (de) 1988-04-14
EP0265685A2 (de) 1988-05-04
JPH10182456A (ja) 1998-07-07
HUT47030A (en) 1989-01-30
JPS6396136A (ja) 1988-04-27
ATA260087A (de) 1997-02-15
ATE78697T1 (de) 1992-08-15
NO1998022I1 (no) 1998-10-12
NL980030I1 (nl) 1999-01-04
AU611863B2 (en) 1991-06-27
GR3006042T3 (xx) 1993-06-21
IE872636L (en) 1988-04-02
FI874281A (fi) 1988-04-03
AR243083A1 (es) 1993-07-30
MA21072A1 (fr) 1988-07-01
NL980030I2 (nl) 1999-10-01
LU90345I2 (fr) 1999-04-06
EG18081A (en) 1991-08-30
FI874281A0 (fi) 1987-09-30
AU7928087A (en) 1988-04-14
US5098910A (en) 1992-03-24
NO874141D0 (no) 1987-10-01
IL84054A0 (en) 1988-03-31
HU199302B (en) 1990-02-28
IE59975B1 (en) 1994-05-04
US5500434A (en) 1996-03-19
MX8639A (es) 1993-11-01
DD272035A5 (de) 1989-09-27
KR880005150A (ko) 1988-06-28
KR970005838B1 (ko) 1997-04-21
NZ221989A (en) 1990-11-27
DE3780753D1 (de) 1992-09-03
AT402894B (de) 1997-09-25
NO175621B (xx) 1994-08-01
DK516487D0 (da) 1987-10-01
PT85843A (de) 1987-11-01
EP0265685A3 (en) 1989-10-11
NO874141L (no) 1988-04-05
EP0265685B1 (de) 1992-07-29
JP3003995B2 (ja) 2000-01-31
PT85843B (pt) 1991-02-08

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