DK167770B1 - Antibiotikum a 40926 n-acylaminoglucuronyl-aglyconer og antibiotikum a 40926 aglycon og farmaceutisk acceptable additionssalte deraf, fremgangsmaade til fremstilling af saadanne forbindelser, farmaceutisk praeparat indeholdende forbindelserne samt anvendelse af saadanne forbindelser til fremstilling af et medikament - Google Patents

Antibiotikum a 40926 n-acylaminoglucuronyl-aglyconer og antibiotikum a 40926 aglycon og farmaceutisk acceptable additionssalte deraf, fremgangsmaade til fremstilling af saadanne forbindelser, farmaceutisk praeparat indeholdende forbindelserne samt anvendelse af saadanne forbindelser til fremstilling af et medikament Download PDF

Info

Publication number
DK167770B1
DK167770B1 DK617286A DK617286A DK167770B1 DK 167770 B1 DK167770 B1 DK 167770B1 DK 617286 A DK617286 A DK 617286A DK 617286 A DK617286 A DK 617286A DK 167770 B1 DK167770 B1 DK 167770B1
Authority
DK
Denmark
Prior art keywords
antibiotic
factor
complex
acid
eluent
Prior art date
Application number
DK617286A
Other languages
Danish (da)
English (en)
Other versions
DK617286A (da
DK617286D0 (da
Inventor
Enrico Selva
Ernesto Riva
Giovanni Cassani
Francesco Parenti
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of DK617286D0 publication Critical patent/DK617286D0/da
Publication of DK617286A publication Critical patent/DK617286A/da
Application granted granted Critical
Publication of DK167770B1 publication Critical patent/DK167770B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK617286A 1986-04-11 1986-12-19 Antibiotikum a 40926 n-acylaminoglucuronyl-aglyconer og antibiotikum a 40926 aglycon og farmaceutisk acceptable additionssalte deraf, fremgangsmaade til fremstilling af saadanne forbindelser, farmaceutisk praeparat indeholdende forbindelserne samt anvendelse af saadanne forbindelser til fremstilling af et medikament DK167770B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868608809A GB8608809D0 (en) 1986-04-11 1986-04-11 Antibiotic
GB8608809 1986-04-11

Publications (3)

Publication Number Publication Date
DK617286D0 DK617286D0 (da) 1986-12-19
DK617286A DK617286A (da) 1987-10-12
DK167770B1 true DK167770B1 (da) 1993-12-13

Family

ID=10596024

Family Applications (1)

Application Number Title Priority Date Filing Date
DK617286A DK167770B1 (da) 1986-04-11 1986-12-19 Antibiotikum a 40926 n-acylaminoglucuronyl-aglyconer og antibiotikum a 40926 aglycon og farmaceutisk acceptable additionssalte deraf, fremgangsmaade til fremstilling af saadanne forbindelser, farmaceutisk praeparat indeholdende forbindelserne samt anvendelse af saadanne forbindelser til fremstilling af et medikament

Country Status (22)

Country Link
US (1) US4868171A (xx)
EP (1) EP0240609B1 (xx)
JP (1) JPH0759593B2 (xx)
KR (2) KR950010461B1 (xx)
CN (1) CN1033043C (xx)
AT (1) ATE70069T1 (xx)
AU (1) AU601706B2 (xx)
DE (1) DE3682767D1 (xx)
DK (1) DK167770B1 (xx)
ES (1) ES2040207T3 (xx)
FI (1) FI86307C (xx)
GB (1) GB8608809D0 (xx)
GR (1) GR3003443T3 (xx)
HU (1) HU196229B (xx)
IE (1) IE59523B1 (xx)
IL (1) IL81106A (xx)
MY (1) MY101178A (xx)
NO (1) NO172121C (xx)
NZ (1) NZ218789A (xx)
PH (1) PH23620A (xx)
PT (1) PT84029B (xx)
ZA (1) ZA869713B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK363587A (da) * 1986-07-30 1988-01-31 Smithkline Beckman Corp Antibiotika og fremstilling heraf under anvendelseaf actinomadura parvosata
GB8621912D0 (en) * 1986-09-11 1986-10-15 Lepetit Spa Increasing ratio of components of anti-biotic complex
DE68925951T2 (de) * 1988-12-27 1996-07-25 Lepetit Spa Chemisches Verfahren zur Herstellung des Antibiotikums L 17392 (Deglukoteicoplanin) und dessen Salze
HUT63860A (en) * 1990-12-05 1993-10-28 Lepetit Spa Process for producing 39-decarboxy-38-(hydroxymethyl) derivatives of teikoplanin antibiotics
US5606036A (en) * 1991-03-27 1997-02-25 Gruppo Lepetit Spa Antibiotic A 40926 ester derivatives
HU210665B (en) 1991-03-27 1995-06-28 Lepetit Spa Process for producing ester derivatives of the antibiotic a 40926 and pharmaceutical compositions containing them as active component
US5750509A (en) * 1991-07-29 1998-05-12 Gruppo Lepetit S.P.A. Amide derivatives of antibiotic A 40926
DK0596929T3 (da) * 1991-07-29 1995-09-11 Lepetit Spa Amidderivater af antibiotikum A 40926
AU701463B2 (en) * 1995-07-05 1999-01-28 Sanofi Aventis S.P.A. Purification of dalbaheptide antibiotics by isoelectric focusing
CA2250578C (en) 1996-04-23 2003-06-24 Versicor Inc. Improved chemical process for preparing amide derivatives of antibiotic a 40926
US7119061B2 (en) 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
US20050090433A1 (en) * 2002-11-18 2005-04-28 Vicuron Pharmaceuticals, Inc Dalbavancin compositions for treatment of bacterial infections
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
CN101851277B (zh) * 2009-03-12 2012-10-03 成都雅途生物技术有限公司 一种道古霉素关键中间体a40926 bo组分的纯化制备方法
CN102417919B (zh) * 2011-09-02 2017-05-24 山东鲁抗医药股份有限公司 一种发酵法生产高纯度替考拉宁的方法
CN110105435B (zh) * 2019-05-08 2023-12-08 宜昌东阳光生化制药有限公司 一种生产a40926的发酵培养基和发酵方法
CN112625925B (zh) * 2021-01-08 2022-04-19 浙江大学 一种达巴万星前体a40926b0高产菌株及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI75190C (fi) * 1982-03-24 1988-05-09 Lilly Co Eli Foerfarande foer framstaellning av ett antibiotikum a41030-komplex eller dess faktorer a, b, c, d, e, f och g.
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
US4521335A (en) * 1983-07-13 1985-06-04 Smithkline Beckman Corporation Aglycone and pseudo-aglycones of the AAD 216 antibiotics
AU579120B2 (en) * 1983-12-16 1988-11-17 Gruppo Lepetit S.P.A. Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
GB8425685D0 (en) * 1984-10-11 1984-11-14 Lepetit Spa Antibiotic a 40926 complex

Also Published As

Publication number Publication date
HUT43869A (en) 1987-12-28
FI86307C (fi) 1992-08-10
EP0240609B1 (en) 1991-12-04
NZ218789A (en) 1990-09-26
IL81106A (en) 1992-07-15
MY101178A (en) 1991-07-31
US4868171A (en) 1989-09-19
HU196229B (en) 1988-10-28
IE863382L (en) 1987-10-11
IE59523B1 (en) 1994-03-09
DK617286A (da) 1987-10-12
KR870010194A (ko) 1987-11-30
GR3003443T3 (en) 1993-02-17
KR960010557B1 (ko) 1996-08-02
DK617286D0 (da) 1986-12-19
FI865320A0 (fi) 1986-12-29
KR950010461B1 (ko) 1995-09-18
PH23620A (en) 1989-09-11
EP0240609A3 (en) 1988-07-27
DE3682767D1 (de) 1992-01-16
CN86108977A (zh) 1988-04-27
EP0240609A2 (en) 1987-10-14
ZA869713B (en) 1987-12-30
GB8608809D0 (en) 1986-05-14
ATE70069T1 (de) 1991-12-15
PT84029B (pt) 1989-01-17
NO172121B (no) 1993-03-01
JPS62242699A (ja) 1987-10-23
NO172121C (no) 1993-06-09
JPH0759593B2 (ja) 1995-06-28
NO865323L (no) 1987-10-12
AU601706B2 (en) 1990-09-20
IL81106A0 (en) 1987-03-31
ES2040207T3 (es) 1993-10-16
CN1033043C (zh) 1996-10-16
FI865320A (fi) 1987-10-12
FI86307B (fi) 1992-04-30
PT84029A (en) 1987-01-01
KR890002231A (ko) 1989-04-08
AU6688386A (en) 1987-10-15

Similar Documents

Publication Publication Date Title
DK167770B1 (da) Antibiotikum a 40926 n-acylaminoglucuronyl-aglyconer og antibiotikum a 40926 aglycon og farmaceutisk acceptable additionssalte deraf, fremgangsmaade til fremstilling af saadanne forbindelser, farmaceutisk praeparat indeholdende forbindelserne samt anvendelse af saadanne forbindelser til fremstilling af et medikament
US4935238A (en) Antibiotic A 40926 complex and its pure factors PA, PB, A, B and B0
KR960010556B1 (ko) 항생물질 a 40926 만노실 아글리콘
DK172934B1 (da) Glykkopeptid-antibiotikum betegnet deacyl A 40926 antibiotikum og farmaceutisk acceptable additionssalte deraf,
KR20070090043A (ko) 항생제 １０７８９１, 그의 팩터 ａ１ 및 ａ２, 제약학상허용되는 염 및 조성물, 및 그의 용도
US5013550A (en) Antibiotics called "chloropolysporins B and C", a process for their preparation, and their therapeutic and veterinary use
EP0254999B1 (en) Antibiotic a 42867 and the addition salts thereof
JP4189026B2 (ja) 抗生物質１０７８９１、そのａ１及びａ２因子、薬学的に許容されるその塩及び組成物、並びにその使用
JP4452505B2 (ja) 抗生物質ｇｅ８１１１２ファクターａ、ｂ、ｂ１、その製薬学的に許容され得る塩および組成物および使用
WO2014085637A1 (en) New lantibiotic derivatives and a process for their preparation
EP0211490B1 (en) Antibiotics of the vancomycin-class
KR100892655B1 (ko) 항생제 １０７８９１, 그의 팩터 ａ１ 및 ａ２, 제약학상허용되는 염 및 조성물, 및 그의 용도
JPH0771479B2 (ja) 抗生物質ａ５１５６８因子ａおよびｂを産生する微生物
JPH01242598A (ja) 抗生物質ａ４２８６７誘導体
NZ227946A (en) Actinomadura strain atcc 39727 useful for producing antibiotic a 40926

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed