DK167580A - Fremgangsmaade til fremstilling af oxazolin- og thiazolinderivater - Google Patents

Fremgangsmaade til fremstilling af oxazolin- og thiazolinderivater

Info

Publication number
DK167580A
DK167580A DK167580A DK167580A DK167580A DK 167580 A DK167580 A DK 167580A DK 167580 A DK167580 A DK 167580A DK 167580 A DK167580 A DK 167580A DK 167580 A DK167580 A DK 167580A
Authority
DK
Denmark
Prior art keywords
alkyl
halogen
optionally substituted
alkoxy
phenyl
Prior art date
Application number
DK167580A
Other languages
English (en)
Inventor
B C C Cantello
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of DK167580A publication Critical patent/DK167580A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Peptides Or Proteins (AREA)
  • Luminescent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK167580A 1979-04-20 1980-04-18 Fremgangsmaade til fremstilling af oxazolin- og thiazolinderivater DK167580A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7913864 1979-04-20

Publications (1)

Publication Number Publication Date
DK167580A true DK167580A (da) 1980-10-21

Family

ID=10504680

Family Applications (1)

Application Number Title Priority Date Filing Date
DK167580A DK167580A (da) 1979-04-20 1980-04-18 Fremgangsmaade til fremstilling af oxazolin- og thiazolinderivater

Country Status (14)

Country Link
US (1) US4409216A (da)
EP (1) EP0018107B1 (da)
JP (1) JPS55141474A (da)
AT (1) ATE2075T1 (da)
AU (1) AU5758880A (da)
DE (1) DE3061396D1 (da)
DK (1) DK167580A (da)
ES (2) ES8105306A1 (da)
FI (1) FI801253A (da)
GR (1) GR67301B (da)
IE (1) IE49697B1 (da)
IL (1) IL59803A0 (da)
NO (1) NO801131L (da)
ZA (1) ZA801970B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2075805B1 (es) * 1993-12-30 1996-10-16 Univ Murcia Procedimiento para la obtencion de iminooxazolinas n-n'-sustituidas.
DE102004008141A1 (de) 2004-02-19 2005-09-01 Abbott Gmbh & Co. Kg Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3023103A (en) * 1960-08-02 1962-02-27 Gen Aniline & Film Corp Antifoggants and stabilizers for photographic silver halide emulsions
DE2205744A1 (de) 1972-02-08 1973-08-09 Thomae Gmbh Dr K Neue durch einen guanidinylidenrest substituierte heterocyclen und verfahren zu ihrer herstellung
NZ183570A (en) * 1976-03-19 1979-06-08 Mcneilab Inc Heterocyclic guanidine derivatives, having anti-secretory and hypogliycaemic activity
CS225804B2 (cs) 1976-03-19 1984-02-13 Mcneilab Inc Způsob výroby heterocyklických derivátů guanidinu
US4089965A (en) * 1976-03-26 1978-05-16 American Cyanamid Company Thiazolylphenylguanidines as antirhinovirus agents
CA1201119A (en) * 1978-09-18 1986-02-25 Mcneilab, Inc. Diaza-cyclic derivatives of guanidine
AU5263779A (en) * 1978-11-29 1980-05-29 Beecham Group Limited Derivatives of thiazolidin-2-ylidene and oxazolidin-2-ylidene with hypoglycaemic acitivity

Also Published As

Publication number Publication date
ES497560A0 (es) 1981-11-16
ES490675A0 (es) 1981-05-16
ES8105306A1 (es) 1981-05-16
GR67301B (da) 1981-06-29
NO801131L (no) 1980-10-21
IL59803A0 (en) 1980-06-30
EP0018107A1 (en) 1980-10-29
US4409216A (en) 1983-10-11
FI801253A (fi) 1980-10-21
JPS55141474A (en) 1980-11-05
ATE2075T1 (de) 1983-01-15
IE800787L (en) 1980-10-20
DE3061396D1 (en) 1983-01-27
IE49697B1 (en) 1985-11-27
AU5758880A (en) 1980-10-23
ES8200668A1 (es) 1981-11-16
ZA801970B (en) 1981-04-29
EP0018107B1 (en) 1982-12-22

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
B1 Patent granted (law 1993)