JPS55141474A - Oxazoline and thiazoline derivative and manufacture - Google Patents

Oxazoline and thiazoline derivative and manufacture

Info

Publication number
JPS55141474A
JPS55141474A JP5155880A JP5155880A JPS55141474A JP S55141474 A JPS55141474 A JP S55141474A JP 5155880 A JP5155880 A JP 5155880A JP 5155880 A JP5155880 A JP 5155880A JP S55141474 A JPS55141474 A JP S55141474A
Authority
JP
Japan
Prior art keywords
alkyl
halogen
optionally substituted
alkoxy
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5155880A
Other languages
English (en)
Inventor
Kurisuchiyan Chiyaaruzu Barii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of JPS55141474A publication Critical patent/JPS55141474A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Peptides Or Proteins (AREA)
  • Luminescent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP5155880A 1979-04-20 1980-04-18 Oxazoline and thiazoline derivative and manufacture Pending JPS55141474A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7913864 1979-04-20

Publications (1)

Publication Number Publication Date
JPS55141474A true JPS55141474A (en) 1980-11-05

Family

ID=10504680

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5155880A Pending JPS55141474A (en) 1979-04-20 1980-04-18 Oxazoline and thiazoline derivative and manufacture

Country Status (14)

Country Link
US (1) US4409216A (ja)
EP (1) EP0018107B1 (ja)
JP (1) JPS55141474A (ja)
AT (1) ATE2075T1 (ja)
AU (1) AU5758880A (ja)
DE (1) DE3061396D1 (ja)
DK (1) DK167580A (ja)
ES (2) ES8105306A1 (ja)
FI (1) FI801253A (ja)
GR (1) GR67301B (ja)
IE (1) IE49697B1 (ja)
IL (1) IL59803A0 (ja)
NO (1) NO801131L (ja)
ZA (1) ZA801970B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2075805B1 (es) * 1993-12-30 1996-10-16 Univ Murcia Procedimiento para la obtencion de iminooxazolinas n-n'-sustituidas.
DE102004008141A1 (de) * 2004-02-19 2005-09-01 Abbott Gmbh & Co. Kg Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3023103A (en) * 1960-08-02 1962-02-27 Gen Aniline & Film Corp Antifoggants and stabilizers for photographic silver halide emulsions
DE2205744A1 (de) 1972-02-08 1973-08-09 Thomae Gmbh Dr K Neue durch einen guanidinylidenrest substituierte heterocyclen und verfahren zu ihrer herstellung
CS225804B2 (cs) 1976-03-19 1984-02-13 Mcneilab Inc Způsob výroby heterocyklických derivátů guanidinu
NZ183570A (en) * 1976-03-19 1979-06-08 Mcneilab Inc Heterocyclic guanidine derivatives, having anti-secretory and hypogliycaemic activity
US4089965A (en) * 1976-03-26 1978-05-16 American Cyanamid Company Thiazolylphenylguanidines as antirhinovirus agents
CA1201119A (en) * 1978-09-18 1986-02-25 Mcneilab, Inc. Diaza-cyclic derivatives of guanidine
AU5263779A (en) * 1978-11-29 1980-05-29 Beecham Group Limited Derivatives of thiazolidin-2-ylidene and oxazolidin-2-ylidene with hypoglycaemic acitivity

Also Published As

Publication number Publication date
IE800787L (en) 1980-10-20
ES8200668A1 (es) 1981-11-16
ES497560A0 (es) 1981-11-16
ZA801970B (en) 1981-04-29
DK167580A (da) 1980-10-21
DE3061396D1 (en) 1983-01-27
NO801131L (no) 1980-10-21
US4409216A (en) 1983-10-11
EP0018107A1 (en) 1980-10-29
ES490675A0 (es) 1981-05-16
ES8105306A1 (es) 1981-05-16
GR67301B (ja) 1981-06-29
IE49697B1 (en) 1985-11-27
ATE2075T1 (de) 1983-01-15
EP0018107B1 (en) 1982-12-22
IL59803A0 (en) 1980-06-30
FI801253A (fi) 1980-10-21
AU5758880A (en) 1980-10-23

Similar Documents

Publication Publication Date Title
AU537414B2 (en) Pyroglutamic acid derivatives
FI892787A0 (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi
CA2247443A1 (en) Substituted 4-hydroxy-phenylalcanoic acid derivatives with agonist activity to ppar-gamma
DK159148C (da) Analogifremgangsmaade til fremstilling af tranexamsyrederivater
ATE3638T1 (de) Sulfonyl-anilin-derivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
ES8101589A1 (es) Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos.
ES463234A1 (es) Procedimiento para preparar compuestos de aril azufre.
PT76812A (en) Process for the preparation of a fungicidal composition containing substituted maleic imides
JPS55141474A (en) Oxazoline and thiazoline derivative and manufacture
ES455909A1 (es) Procedimiento para preparar derivados de piperacina.
PT73659A (en) Ethenylimidazole derivatives with antimycotic activity processes for their preparation and pharmaceutical compositions containing them intermediates useful in their preparation and a process for the preparation thereof
ES551421A0 (es) Un procedimiento para preparar imidazol-5-carboximidatos
ES8603844A1 (es) Procedimiento para la obtencion de esteres de acido fenoxialcancarboxilico sustituidos
ES476632A1 (es) Procedimiento para preparar derivados de anilida con susti--tucion heterociclica.
ES8503655A1 (es) Un procedimiento para preparar nuevas dihidropiridinas.
ES8200661A1 (es) Un procedimiento para la preparacion de nuevos derivados de dihidropiridina
SE8000298L (sv) Karbamatderivat av merkaptoacylhydroxiproliner
ES8401758A1 (es) "metodo de preparar derivados isoxazol-5-il-metilenoxiguanidinicos".
ES8606245A1 (es) Procedimiento para preparar fenoxianilinas y piridiloxianilinas sustituidas
AU579416B2 (en) 3-Amino-2,3-dihydro-1-benzoxepine-compounds and methods for their preparation and pharmaceutical preparations containing these compounds
ATE18042T1 (de) Semicarbazide, ihre herstellung und verwendung.