DK167250B1 - 9-amino-acridinderivater, fremgangsmaade til deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse til fremstilling af laegemidler - Google Patents

9-amino-acridinderivater, fremgangsmaade til deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse til fremstilling af laegemidler Download PDF

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Publication number
DK167250B1
DK167250B1 DK488885A DK488885A DK167250B1 DK 167250 B1 DK167250 B1 DK 167250B1 DK 488885 A DK488885 A DK 488885A DK 488885 A DK488885 A DK 488885A DK 167250 B1 DK167250 B1 DK 167250B1
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Prior art keywords
solid
solution
compound
give
formula
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DK488885A
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Danish (da)
English (en)
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DK488885A (da
DK488885D0 (da
Inventor
Gregory M Shutske
Frank A Pierrat
Original Assignee
Hoechst Roussel Pharma
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Filing date
Publication date
Priority claimed from US06/664,731 external-priority patent/US4631286A/en
Priority claimed from US06/781,155 external-priority patent/US4695573A/en
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK488885D0 publication Critical patent/DK488885D0/da
Publication of DK488885A publication Critical patent/DK488885A/da
Application granted granted Critical
Publication of DK167250B1 publication Critical patent/DK167250B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK488885A 1984-10-25 1985-10-24 9-amino-acridinderivater, fremgangsmaade til deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse til fremstilling af laegemidler DK167250B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66473184 1984-10-25
US06/664,731 US4631286A (en) 1984-10-25 1984-10-25 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US78115585 1985-10-01
US06/781,155 US4695573A (en) 1984-10-25 1985-10-01 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds

Publications (3)

Publication Number Publication Date
DK488885D0 DK488885D0 (da) 1985-10-24
DK488885A DK488885A (da) 1986-04-26
DK167250B1 true DK167250B1 (da) 1993-09-27

Family

ID=27099040

Family Applications (2)

Application Number Title Priority Date Filing Date
DK488885A DK167250B1 (da) 1984-10-25 1985-10-24 9-amino-acridinderivater, fremgangsmaade til deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse til fremstilling af laegemidler
DK141992A DK168704B1 (da) 1984-10-25 1992-11-26 N-(3-Oxocyclohexen-1-yl)-2-aminobenzonitrilderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK141992A DK168704B1 (da) 1984-10-25 1992-11-26 N-(3-Oxocyclohexen-1-yl)-2-aminobenzonitrilderivater

Country Status (20)

Country Link
US (1) US4839364A (xx)
EP (1) EP0179383B1 (xx)
JP (1) JPH01125362A (xx)
KR (1) KR900007624B1 (xx)
AR (1) AR247394A1 (xx)
AT (1) ATE63903T1 (xx)
AU (2) AU589141B2 (xx)
CA (1) CA1292744C (xx)
DE (1) DE3582995D1 (xx)
DK (2) DK167250B1 (xx)
ES (3) ES8701165A1 (xx)
FI (1) FI86421C (xx)
GR (1) GR852555B (xx)
HU (1) HU196183B (xx)
IE (1) IE58696B1 (xx)
IL (3) IL76796A (xx)
NO (1) NO172847C (xx)
NZ (2) NZ213932A (xx)
PH (1) PH22614A (xx)
PT (1) PT81362B (xx)

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US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine
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US5280032A (en) * 1989-02-14 1994-01-18 Toyama Chemical Co., Ltd. 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
US5053513A (en) * 1990-03-29 1991-10-01 Hoechst-Roussel Pharmaceuticals Incorporated Method of reducing a carbonyl containing acridine
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KR100381716B1 (ko) * 2000-10-09 2003-04-26 한국화학연구원 항암활성을 가지는 아크리딘 유도체
US20050222123A1 (en) 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
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US20060183800A1 (en) * 2004-11-12 2006-08-17 Xianqi Kong Methods and fluorinated compositions for treating amyloid-related diseases
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EP3094622A1 (en) * 2014-01-15 2016-11-23 Centre National de la Recherche Scientifique (C.N.R.S.) Water soluble 4-azapodophyllotoxin analogs
KR101586473B1 (ko) * 2014-04-30 2016-01-19 (주)이컴프 스크롤 압축기
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Also Published As

Publication number Publication date
FI854156A0 (fi) 1985-10-23
EP0179383A2 (en) 1986-04-30
NO172847B (no) 1993-06-07
PT81362B (pt) 1987-11-30
IE852632L (en) 1986-04-25
IL76796A0 (en) 1986-02-28
NZ213932A (en) 1990-12-21
IL90300A (en) 1990-11-29
DK488885A (da) 1986-04-26
IE58696B1 (en) 1993-11-03
DK488885D0 (da) 1985-10-24
JPH0584306B2 (xx) 1993-12-01
HU196183B (en) 1988-10-28
AU615768B2 (en) 1991-10-10
NZ229248A (en) 1990-12-21
AU3823489A (en) 1989-10-26
ATE63903T1 (de) 1991-06-15
KR860003227A (ko) 1986-05-21
NO172847C (no) 1993-09-15
ES554569A0 (es) 1988-01-01
EP0179383A3 (en) 1987-01-28
PT81362A (en) 1985-11-01
EP0179383B1 (en) 1991-05-29
AU4903885A (en) 1986-05-01
CA1292744C (en) 1991-12-03
IL76796A (en) 1990-03-19
FI86421B (fi) 1992-05-15
AR247394A1 (es) 1994-12-29
NO904711L (no) 1986-04-28
ES8701165A1 (es) 1986-11-16
DE3582995D1 (de) 1991-07-04
IL90300A0 (en) 1989-12-15
FI86421C (fi) 1992-08-25
ES554568A0 (es) 1988-05-16
AU589141B2 (en) 1989-10-05
DK141992A (da) 1992-11-26
FI854156L (fi) 1986-04-26
US4839364A (en) 1989-06-13
KR900007624B1 (ko) 1990-10-17
ES8801213A1 (es) 1988-01-01
GR852555B (xx) 1986-02-24
JPH01125362A (ja) 1989-05-17
DK141992D0 (da) 1992-11-26
PH22614A (en) 1988-10-17
HUT41009A (en) 1987-03-30
ES8802383A1 (es) 1988-05-16
DK168704B1 (da) 1994-05-24
NO904711D0 (no) 1990-10-30
ES548137A0 (es) 1986-11-16

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