DK1663287T3 - Anvendelse af modificerede cyclosporiner til behandling af HCV-sygdomme - Google Patents

Anvendelse af modificerede cyclosporiner til behandling af HCV-sygdomme

Info

Publication number
DK1663287T3
DK1663287T3 DK04764762T DK04764762T DK1663287T3 DK 1663287 T3 DK1663287 T3 DK 1663287T3 DK 04764762 T DK04764762 T DK 04764762T DK 04764762 T DK04764762 T DK 04764762T DK 1663287 T3 DK1663287 T3 DK 1663287T3
Authority
DK
Denmark
Prior art keywords
treatment
cyclosporins
hcv diseases
hcv
modified
Prior art date
Application number
DK04764762T
Other languages
Danish (da)
English (en)
Inventor
Makoto Hijikata
Kunitada Shimotohno
Koichi Watashi
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1663287T3 publication Critical patent/DK1663287T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK04764762T 2003-09-03 2004-09-02 Anvendelse af modificerede cyclosporiner til behandling af HCV-sygdomme DK1663287T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0320638.0A GB0320638D0 (en) 2003-09-03 2003-09-03 Organic compounds
PCT/EP2004/009804 WO2005021028A1 (en) 2003-09-03 2004-09-02 Use of modified cyclosporins for the treatment of hcv disorders

Publications (1)

Publication Number Publication Date
DK1663287T3 true DK1663287T3 (da) 2009-11-09

Family

ID=28686843

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04764762T DK1663287T3 (da) 2003-09-03 2004-09-02 Anvendelse af modificerede cyclosporiner til behandling af HCV-sygdomme

Country Status (29)

Country Link
US (1) US7968518B2 (sl)
EP (2) EP1797892B1 (sl)
JP (1) JP4688806B2 (sl)
KR (1) KR101116968B1 (sl)
CN (1) CN1842343A (sl)
AU (2) AU2004268382A1 (sl)
BR (1) BRPI0414062B8 (sl)
CA (1) CA2537137C (sl)
CY (1) CY1110506T1 (sl)
DE (1) DE602004022061D1 (sl)
DK (1) DK1663287T3 (sl)
ES (1) ES2328361T3 (sl)
GB (1) GB0320638D0 (sl)
HR (1) HRP20090535T1 (sl)
IL (1) IL173909A (sl)
IS (1) IS2917B (sl)
MA (1) MA28032A1 (sl)
MX (1) MXPA06002394A (sl)
NO (1) NO20061479L (sl)
NZ (1) NZ545495A (sl)
PL (1) PL1663287T3 (sl)
PT (1) PT1663287E (sl)
RU (1) RU2389501C2 (sl)
SG (1) SG149063A1 (sl)
SI (1) SI1663287T1 (sl)
TN (1) TNSN06071A1 (sl)
TW (1) TWI342782B (sl)
WO (1) WO2005021028A1 (sl)
ZA (1) ZA200601550B (sl)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1091975B1 (fr) 1998-07-01 2005-12-14 Debiopharm S.A. Nouvelle cyclosporine ayant un profil d'activite ameliore
US7538084B2 (en) 2003-03-17 2009-05-26 Amr Technology, Inc. Cyclosporins
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
GB0500020D0 (en) * 2005-01-04 2005-02-09 Novartis Ag Organic compounds
CN1984671A (zh) * 2004-07-14 2007-06-20 诺瓦提斯公司 环孢菌素和peg化干扰素的组合用于治疗丙型肝炎病毒(hcv)的用途
WO2006039164A2 (en) 2004-09-29 2006-04-13 Amr Technology, Inc. Novel cyclosporin analogues and their pharmaceutical uses
EP1809656A4 (en) 2004-09-29 2009-03-25 Amr Technology Inc CYCLOSPORINAL KINANALOGA AND ITS PHARMACEUTICAL APPLICATIONS
US7196161B2 (en) * 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
EP1793844B1 (en) 2004-10-01 2010-12-08 Debiopharm S.A. Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection
WO2006039668A2 (en) * 2004-10-01 2006-04-13 Scynexis, Inc 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection
EP1812037A4 (en) 2004-10-06 2009-11-11 Amr Technology Inc ALKYNES OF CYCLOSPORINE AND THEIR USEFUL AS PHARMACEUTICAL AGENTS
US7696167B2 (en) 2004-11-22 2010-04-13 Astellas Pharma Inc. Cyclic peptide compound
NZ555142A (en) * 2004-12-23 2010-03-26 Novartis Ag Compounds for flaviviridae treatment
AU2005322242B2 (en) * 2004-12-23 2010-02-11 Novartis Ag Compositions for HCV treatment
CA2611151A1 (en) 2005-06-17 2006-12-28 Novartis Ag Use of sanglifehrin in hcv
CN101316606B (zh) * 2005-09-30 2015-05-27 西尼克斯公司 治疗和预防丙型肝炎感染的方法和药物组合物
DE602006020152D1 (de) 2005-09-30 2011-03-31 Scynexis Inc Arylalkyl- und heteroarylalkyl-derivate von cyclosporin a bei der behandlung und vorbeugung einer virusinfektion
NZ567262A (en) * 2005-09-30 2011-12-22 Scynexis Inc Cyclosporin derivatives and their use for the treatment and prevention of hepatitis C infection
KR101273681B1 (ko) * 2005-10-26 2013-06-25 아스텔라스세이야쿠 가부시키가이샤 신규 시클릭 펩티드 화합물
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
AU2007254148B2 (en) 2006-05-19 2013-02-07 Scynexis, Inc. Method for the treatment and prevention of ocular disorders
WO2007141395A1 (fr) * 2006-06-02 2007-12-13 Claude Annie Perrichon Gestion des electrons actifs
MX2009003743A (es) * 2006-10-12 2009-06-18 Novartis Ag Uso de ciclosporinas modificadas.
WO2008069917A2 (en) * 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
BRPI0806265A2 (pt) * 2007-01-04 2011-09-06 Debiopharm Sa ciclosporina não-imunossupressora para tratamento de distrofia muscular congênita de ullrich
RU2436795C2 (ru) * 2007-05-02 2011-12-20 Астеллас Фарма Инк. Новые циклические пептидные соединения
WO2009028418A1 (ja) 2007-08-24 2009-03-05 Sapporo Medical University シクロスポリンa結合タンパク質
EP2280989B1 (en) 2008-06-06 2016-02-10 Scynexis, Inc. Cyclosporin analogs and their use in the treatment of hcv infections
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
CN102164948A (zh) * 2008-07-30 2011-08-24 伊索技术制药公司 非免疫抑制的环孢菌素类似分子
MX2011003259A (es) * 2008-09-24 2011-04-21 Astellas Pharma Inc Compuesto de peptido y metodo para producir el mismo.
EA020896B1 (ru) * 2008-11-06 2015-02-27 Дебио Решерш Фармасетик С.А. Циклоундекадепсипептидные соединения и применение указанных соединений в качестве лекарственного средства
EP2376524B1 (en) * 2008-12-31 2017-03-15 Cypralis Limited Derivatives of cyclosporin a
MX2011008000A (es) * 2009-01-30 2011-09-15 Enanta Pharm Inc Analogos de ciclosporina para la prevención o tratamiento de la infeccion de hepatitis c.
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
JP2013513595A (ja) 2009-12-09 2013-04-22 サイネクシス,インコーポレーテッド 新規環状ペプチド
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
MX2013003903A (es) 2010-10-05 2013-05-20 Novartis Ag Nuevos tratamientos de infeccion por el virus de hepatitis c.
CN105381450A (zh) 2010-11-30 2016-03-09 诺华有限公司 丙型肝炎病毒感染的新疗法
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
CN107496902B (zh) 2010-12-15 2022-01-18 康卓维尔制药公司 在氨基酸1和3位修改的环孢菌素类似分子
JP2014509628A (ja) 2011-03-31 2014-04-21 ノバルティス アーゲー C型肝炎ウイルス感染症を治療するためのアリスポリビル
CN103458913A (zh) 2011-04-01 2013-12-18 诺华股份有限公司 对乙型肝炎病毒感染或其与丁型肝炎病毒感染及相关肝脏疾病结合的治疗
SG193908A1 (en) 2011-04-13 2013-11-29 Novartis Ag Treatment of hepatitis c virus infection with alisporivir
RU2014116988A (ru) 2011-09-27 2015-11-10 Новартис Аг Алиспоривир для лечения инфекции, вызванной вирусом гепатита с
MX2014013625A (es) 2012-05-07 2015-02-05 Novartis Ag Modulacion farmacocinetica con alisporivir.
JP2015519368A (ja) 2012-06-01 2015-07-09 アラーガン インコーポレイテッドAllergan,Incorporated シクロスポリンa類似体
WO2014085623A1 (en) 2012-11-28 2014-06-05 Enanta Pharmaceuticals, Inc. Novel [n-me-4-hydroxyleucine]-9-cyclosporin analogues
WO2015008223A1 (en) 2013-07-17 2015-01-22 Novartis Ag Treatment of hepatitis c virus infection with alisporivir and ribavirin
SG11201601274QA (en) 2013-08-26 2016-03-30 Enanta Pharm Inc Cyclosporin analogues for preventing or treating hepatitis c
WO2015136455A1 (en) 2014-03-13 2015-09-17 Novartis Ag New treatments of hepatitis c virus infection
US9669095B2 (en) 2014-11-03 2017-06-06 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis C infection
TW201639873A (zh) 2015-01-08 2016-11-16 歐樂根公司 Mebmt側鏈已環化之環孢菌素衍生物
AU2021333748A1 (en) * 2020-08-24 2023-03-23 Nanomerics Ltd Viral inhibitors

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
US4917888A (en) 1985-06-26 1990-04-17 Cetus Corporation Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
JP2514950B2 (ja) 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質,その製造法および中間体
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
SK278808B6 (sk) * 1990-11-02 1998-03-04 Novartis Ag Cyklosporíny, ich použitie pri príprave liečiva na
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5382657A (en) 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
US6174868B1 (en) * 1992-09-10 2001-01-16 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of hepatitis C virus-associated diseases
EP0627406B1 (en) 1992-10-21 1998-10-28 Yoshitomi Pharmaceutical Industries, Ltd. 2-amino-1,3-propanediol compound and immunosuppressant
KR960705579A (ko) 1993-11-10 1996-11-08 에릭에스. 딕커 개선된 인터페론 중합체 결합체(Improved interferon polymer conjugates)
ATE211726T1 (de) 1994-08-22 2002-01-15 Welfide Corp Benzolderivate und deren medizinische verwendung
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
JP3786447B2 (ja) * 1995-03-31 2006-06-14 エーザイ株式会社 C型肝炎の予防・治療剤
US5908621A (en) 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
FR2757521B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757520B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent
FR2757522B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
DE69830756T2 (de) 1997-04-04 2006-05-04 Mitsubishi Pharma Corp. 2-Aminopropan-1,3-diol-Verbindungen, ihre medizinische Anwendung und Zwischenprodukte zu ihrer Synthese
JPH1180026A (ja) * 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
GB9811854D0 (en) * 1998-06-02 1998-07-29 Ciba Geigy Ag Organic compounds
EP1091975B1 (fr) 1998-07-01 2005-12-14 Debiopharm S.A. Nouvelle cyclosporine ayant un profil d'activite ameliore
IL153594A0 (en) 2000-07-13 2003-07-06 Sankyo Co Amino alcohol derivatives and pharmaceutical compositions containing the same
JP2004507552A (ja) 2000-08-31 2004-03-11 メルク エンド カムパニー インコーポレーテッド 免疫調節剤としてのリン酸誘導体
AR031010A1 (es) * 2000-10-19 2003-09-03 Fujisawa Pharmaceutical Co Una composicion farmaceutica, util para inhibir el dano celular
JP2002125683A (ja) * 2000-10-27 2002-05-08 Tokyoto Igaku Kenkyu Kiko インターフェロンの有効性を予測する方法並びにそれに用いられるプライマー及びプローブ
DE60208355T2 (de) 2001-03-26 2006-07-27 Novartis Ag 2-amino-propanol derivate
JP2002316985A (ja) 2001-04-20 2002-10-31 Sankyo Co Ltd ベンゾチオフェン誘導体
DE60223699T2 (de) 2001-09-27 2008-10-30 Kyorin Pharmaceutical Co., Ltd. Diarylsulfidderivat, dessen additionssalz und immunsuppressivum
DE60235900D1 (de) 2001-09-27 2010-05-20 Kyorin Seiyaku Kk Osuppressivum
JP4430941B2 (ja) 2002-01-18 2010-03-10 メルク エンド カムパニー インコーポレーテッド Edg受容体作動薬
EP1575964B1 (en) 2002-01-18 2009-11-11 Merck & Co., Inc. N-(benzyl)aminoalkyl carboxylate, phosphinates, phosphonates and tetrazoles as edg receptor agonists
US20030213603A1 (en) * 2002-05-14 2003-11-20 Fisher David B. Dual use extension apparatus for a tool
BR0312278A (pt) 2002-06-28 2007-06-19 Idenix Cayman Ltd éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae
GB0313444D0 (en) 2003-06-11 2003-07-16 Midland Medical Technologies L Modular dysplasia cup
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
EP1793844B1 (en) 2004-10-01 2010-12-08 Debiopharm S.A. Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection
AU2005322242B2 (en) 2004-12-23 2010-02-11 Novartis Ag Compositions for HCV treatment

Also Published As

Publication number Publication date
JP2007504260A (ja) 2007-03-01
GB0320638D0 (en) 2003-10-01
ZA200601550B (en) 2007-05-30
RU2389501C2 (ru) 2010-05-20
MXPA06002394A (es) 2006-06-20
PL1663287T3 (pl) 2009-12-31
CY1110506T1 (el) 2015-04-29
ES2328361T3 (es) 2009-11-12
US20070275884A1 (en) 2007-11-29
CN1842343A (zh) 2006-10-04
EP1797892A1 (en) 2007-06-20
RU2006110533A (ru) 2007-10-10
CA2537137C (en) 2013-05-28
BRPI0414062A (pt) 2006-10-24
IS2917B (is) 2014-12-15
NO20061479L (no) 2006-06-02
PT1663287E (pt) 2009-09-03
BRPI0414062B1 (pt) 2019-06-25
AU2008203031A1 (en) 2008-07-31
TNSN06071A1 (en) 2007-10-03
NZ545495A (en) 2010-01-29
EP1663287B1 (en) 2009-07-15
KR101116968B1 (ko) 2012-03-14
EP1663287A1 (en) 2006-06-07
BRPI0414062B8 (pt) 2021-05-25
JP4688806B2 (ja) 2011-05-25
IL173909A0 (en) 2006-07-05
WO2005021028A1 (en) 2005-03-10
US7968518B2 (en) 2011-06-28
HK1091732A1 (en) 2007-01-26
MA28032A1 (fr) 2006-07-03
TW200524626A (en) 2005-08-01
IL173909A (en) 2011-03-31
AU2008203031B2 (en) 2011-04-07
IS8371A (is) 2006-03-24
TWI342782B (en) 2011-06-01
SG149063A1 (en) 2009-01-29
AU2004268382A1 (en) 2005-03-10
CA2537137A1 (en) 2005-03-10
DE602004022061D1 (de) 2009-08-27
SI1663287T1 (sl) 2009-10-31
KR20060132798A (ko) 2006-12-22
EP1797892B1 (en) 2013-10-23
HRP20090535T1 (hr) 2009-11-30

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