DK1617876T3 - Thorium-227 til anvendelse i strålebehandling af bløddels-sygdomme - Google Patents

Thorium-227 til anvendelse i strålebehandling af bløddels-sygdomme

Info

Publication number
DK1617876T3
DK1617876T3 DK04727587.0T DK04727587T DK1617876T3 DK 1617876 T3 DK1617876 T3 DK 1617876T3 DK 04727587 T DK04727587 T DK 04727587T DK 1617876 T3 DK1617876 T3 DK 1617876T3
Authority
DK
Denmark
Prior art keywords
thorium
radiation treatment
bleeding diseases
bleeding
diseases
Prior art date
Application number
DK04727587.0T
Other languages
English (en)
Inventor
Roy Larsen
Oyvind Bruland
Original Assignee
Algeta As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0308731.9A external-priority patent/GB0308731D0/en
Application filed by Algeta As filed Critical Algeta As
Application granted granted Critical
Publication of DK1617876T3 publication Critical patent/DK1617876T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • A61K51/1096Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies radioimmunotoxins, i.e. conjugates being structurally as defined in A61K51/1093, and including a radioactive nucleus for use in radiotherapeutic applications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicinal Preparation (AREA)
DK04727587.0T 2003-04-15 2004-04-15 Thorium-227 til anvendelse i strålebehandling af bløddels-sygdomme DK1617876T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0308731.9A GB0308731D0 (en) 2003-04-15 2003-04-15 Method of radiotherapy
PCT/GB2004/001654 WO2004091668A1 (en) 2003-04-15 2004-04-15 Thorium-227 for use in radiotherapy of soft tissue disease

Publications (1)

Publication Number Publication Date
DK1617876T3 true DK1617876T3 (da) 2014-07-21

Family

ID=35385222

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04727587.0T DK1617876T3 (da) 2003-04-15 2004-04-15 Thorium-227 til anvendelse i strålebehandling af bløddels-sygdomme

Country Status (19)

Country Link
EP (1) EP1617876B1 (da)
JP (2) JP5006032B2 (da)
KR (2) KR20060015507A (da)
CN (1) CN100586484C (da)
AU (1) AU2004229218B2 (da)
BR (1) BRPI0409387B8 (da)
CA (1) CA2522148C (da)
CY (1) CY1115407T1 (da)
DK (1) DK1617876T3 (da)
EA (1) EA008195B1 (da)
ES (1) ES2486845T3 (da)
HK (1) HK1094150A1 (da)
IL (1) IL171148A (da)
MX (1) MXPA05010804A (da)
NO (1) NO332931B1 (da)
NZ (3) NZ543044A (da)
PL (1) PL1617876T3 (da)
PT (1) PT1617876E (da)
ZA (1) ZA200507983B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA008195B1 (ru) * 2003-04-15 2007-04-27 Алгета Ас Применение тория-227 в лучевой терапии заболеваний мягких тканей
GB201002508D0 (en) * 2010-02-12 2010-03-31 Algeta As Product
GB201007354D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
GB201105298D0 (en) * 2011-03-29 2011-05-11 Algeta Asa Pharmaceutical preparation
GB201600154D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
GB201600153D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
ES2952744T3 (es) 2016-12-15 2023-11-03 Nestle Sa Composiciones y procedimientos que modulan los glóbulos blancos o los neutrófilos en un animal de compañía
FR3088769B1 (fr) * 2018-11-15 2020-12-25 Orano Med Procede de preparation d'au moins un generateur a haute teneur en radium-228
RU2767567C1 (ru) * 2020-10-27 2022-03-17 Станислав Анатольевич Дороватовский Комплексные соединения, содержащие в своем составе радионуклид 227Th, а также бисфосфонатный фрагмент, способы их получения, а также потенциальное применение в качестве действующего вещества в составе остеотропного радиофармацевтического лекарственного препарата

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2053196T3 (es) * 1989-06-19 1994-07-16 Akzo Nv Metodo para la produccion de un radioinmunoconjugado.
EP0662842A1 (en) * 1992-04-13 1995-07-19 The Dow Chemical Company Process for preparing macrocyclic chelating agents and formation of chelates and conjugates thereof
MY133346A (en) * 1999-03-01 2007-11-30 Biogen Inc Kit for radiolabeling ligands with yttrium-90
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
CA2381123C (en) * 2000-02-25 2011-10-04 Dangshe Ma Actinium-225 complexes and conjugates for radioimmunotherapy
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
ITMI20022411A1 (it) * 2002-11-14 2004-05-15 Bracco Imaging Spa Agenti per la diagnosi e la terapia di tumori che espongono sulla superficie delle cellule proteine alterate.
EA008195B1 (ru) * 2003-04-15 2007-04-27 Алгета Ас Применение тория-227 в лучевой терапии заболеваний мягких тканей

Also Published As

Publication number Publication date
EP1617876A1 (en) 2006-01-25
IL171148A (en) 2013-12-31
NO20055390L (no) 2006-01-16
NZ543044A (en) 2010-04-30
KR20060015507A (ko) 2006-02-17
CN1805760A (zh) 2006-07-19
CY1115407T1 (el) 2017-01-04
BRPI0409387A (pt) 2006-04-18
CN100586484C (zh) 2010-02-03
JP5006032B2 (ja) 2012-08-22
MXPA05010804A (es) 2006-03-09
ZA200507983B (en) 2007-03-28
EP1617876B1 (en) 2014-05-14
NZ595758A (en) 2013-02-22
JP5468597B2 (ja) 2014-04-09
BRPI0409387B8 (pt) 2021-05-25
CA2522148A1 (en) 2004-10-28
JP2006523664A (ja) 2006-10-19
KR101274867B1 (ko) 2013-06-13
AU2004229218A1 (en) 2004-10-28
NO20055390D0 (no) 2005-11-15
NO332931B1 (no) 2013-02-04
PL1617876T3 (pl) 2015-03-31
BRPI0409387B1 (pt) 2021-05-11
AU2004229218B2 (en) 2009-05-07
CA2522148C (en) 2010-07-13
KR20110022743A (ko) 2011-03-07
JP2012051942A (ja) 2012-03-15
PT1617876E (pt) 2014-08-04
EA008195B1 (ru) 2007-04-27
EA200501456A1 (ru) 2006-06-30
ES2486845T3 (es) 2014-08-19
NZ606996A (en) 2014-08-29
HK1094150A1 (en) 2007-03-23

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