DK164543C - Salte af l-carnitin og alkanoyl-l-carnitiner, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne - Google Patents

Salte af l-carnitin og alkanoyl-l-carnitiner, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne

Info

Publication number
DK164543C
DK164543C DK609984A DK609984A DK164543C DK 164543 C DK164543 C DK 164543C DK 609984 A DK609984 A DK 609984A DK 609984 A DK609984 A DK 609984A DK 164543 C DK164543 C DK 164543C
Authority
DK
Denmark
Prior art keywords
carnitin
carnitines
alkanoyl
procedures
salts
Prior art date
Application number
DK609984A
Other languages
English (en)
Other versions
DK609984A (da
DK164543B (da
DK609984D0 (da
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT49594/83A external-priority patent/IT1172394B/it
Priority claimed from IT49123/84A external-priority patent/IT1178203B/it
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of DK609984D0 publication Critical patent/DK609984D0/da
Publication of DK609984A publication Critical patent/DK609984A/da
Publication of DK164543B publication Critical patent/DK164543B/da
Application granted granted Critical
Publication of DK164543C publication Critical patent/DK164543C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK609984A 1983-12-28 1984-12-19 Salte af l-carnitin og alkanoyl-l-carnitiner, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne DK164543C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT49594/83A IT1172394B (it) 1983-12-28 1983-12-28 Sali della l-carnitina e di alcuni alcanoil derivati della l-carnitina e procedimento per la loro preparazione
IT4959483 1983-12-28
IT4912384 1984-11-06
IT49123/84A IT1178203B (it) 1984-11-06 1984-11-06 Orotati di alcanoil l-carnitine e procedimento per la loro preparazione

Publications (4)

Publication Number Publication Date
DK609984D0 DK609984D0 (da) 1984-12-19
DK609984A DK609984A (da) 1985-06-29
DK164543B DK164543B (da) 1992-07-13
DK164543C true DK164543C (da) 1992-12-07

Family

ID=26329370

Family Applications (1)

Application Number Title Priority Date Filing Date
DK609984A DK164543C (da) 1983-12-28 1984-12-19 Salte af l-carnitin og alkanoyl-l-carnitiner, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne

Country Status (9)

Country Link
US (1) US4602039A (da)
EP (1) EP0150688B1 (da)
KR (1) KR900003020B1 (da)
CA (1) CA1252098A (da)
DE (1) DE3463261D1 (da)
DK (1) DK164543C (da)
ES (1) ES539072A0 (da)
GR (1) GR82612B (da)
IE (1) IE57942B1 (da)

Families Citing this family (60)

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DE3635864A1 (de) * 1986-06-26 1988-05-05 Gerhard Gergely Verfahren zum herstellen eines brausegranulates, danach hergestelltes brausegranulat sowie dessen verwendung
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FR2619007B1 (fr) * 1987-08-07 1990-09-28 Dermatologiques Et Preparations cosmetiques a action lipolytique
DE3841664A1 (de) * 1988-12-10 1990-10-11 Fresenius Ag Nicht-hygroskopisches salz des l-carnitins
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IT1272290B (it) 1994-06-20 1997-06-16 Avantgarde Spa Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee
CN1177807C (zh) * 1996-05-31 2004-12-01 希格马托制药工业公司 稳定的、非吸湿性的l(-)肉碱和链烷酰基l(-)肉碱的盐和其制备方法以及含有此盐的固体口服组合物
IT1289974B1 (it) * 1997-02-25 1998-10-19 Aldo Fassi Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine
US6337320B1 (en) 1996-10-11 2002-01-08 Thione International, Inc. Reparatives for ultraviolet radiation skin damage
IT1291126B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine
IT1291127B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
IT1291133B1 (it) * 1997-04-07 1998-12-29 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti l-carnitina e alcanoil l-carnitine magnesio tartrato
IT1291134B1 (it) * 1997-04-08 1998-12-29 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti una alcanoil l-carnitina magnesio citrato
IT1291143B1 (it) * 1997-04-18 1998-12-29 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina
IT1290600B1 (it) * 1997-04-30 1998-12-10 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti l-carnitina e alcanoil l-carnitine magnesio fumarato
US6138683A (en) * 1997-09-19 2000-10-31 Thione International, Inc. Smokeless tobacco products containing antioxidants
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IT1299544B1 (it) 1998-07-03 2000-03-16 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine
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AU1295700A (en) * 1998-11-26 2000-06-13 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia
IT1312018B1 (it) * 1999-03-19 2002-04-04 Fassi Aldo Procedimento migliorato per la produzione di sali non igroscopicidella l(-)-carnitina.
IT1305308B1 (it) * 1999-03-26 2001-05-04 Biosint S P A Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione
IT1306147B1 (it) * 1999-05-28 2001-05-30 Biosalts Srl Derivati di principi attivi ad attivita' terapeutica e/o nutrizionalee composizioni atte alla somministrazione orale contenenti tali
JP2003508488A (ja) * 1999-09-03 2003-03-04 シグマ−タウ・ヘルスサイエンス・ソシエタ・ペル・アチオニ 超微細ｌ−カルニチン、その調製方法、それを含む組成物、及びその使用方法
US6914076B2 (en) * 2000-01-19 2005-07-05 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis
US6429230B1 (en) * 2000-01-19 2002-08-06 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis
US6335369B1 (en) * 2000-01-19 2002-01-01 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis
US6740338B1 (en) 2000-01-20 2004-05-25 Raj K. Chopra Reduced form of Cenzyme Q in high bioavailability stable oral dosage form
US8753675B1 (en) 2000-01-20 2014-06-17 Raj K. Chopra Reduced form of Coenzyme Q in high bioavailability stable dosage forms and related applications
IT1317013B1 (it) * 2000-04-12 2003-05-26 Biosalts Srl Sostanze dolcificanti, particolarmente per il caffe' ed il the'.
IT1317042B1 (it) * 2000-06-14 2003-05-26 Biosalts Srl Fumarati doppi di una carnitina e creatina, e integratori alimentari,dietetici e farmaci che li contengono.
DK1326502T3 (da) * 2000-08-29 2005-08-22 Lonza Ag Fremgangsmåde til fremstilling af en blanding, som kan granuleres, samt carnitin-magnesium-hydroxycitrat
US6441050B1 (en) 2000-08-29 2002-08-27 Raj K. Chopra Palatable oral coenzyme Q liquid
IT1317924B1 (it) * 2000-10-31 2003-07-15 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti salinon igroscopici della l-carnitina e delle alcanoil l-carnitine con
ITRM20010030A1 (it) * 2001-01-23 2002-07-23 Aldo Fassi Sali di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per la loro pr
ITRM20010044A1 (it) * 2001-01-29 2002-07-29 Sigma Tau Healthscience Spa Integratore alimentare ad effetto dimagrante.
ITRM20010293A1 (it) * 2001-05-29 2002-11-29 Sigma Tau Ind Farmaceuti Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore.
ITRM20010445A1 (it) * 2001-07-25 2003-01-27 Sigma Tau Healthscience Spa Alfa-chetoglutarati di principi attivi e composizioni che li contengono.
ITRM20010729A1 (it) * 2001-12-12 2003-06-12 Aldo Fassi Sale di acetil l-carnitina con un acido organico dicarbossilico e procedimento per la sua preparazione.
ITRM20020055A1 (it) * 2002-02-04 2003-08-04 Aldo Fassi Sali metallici di carnitine, integratori dietetici/nutritivi che li contengono e kit dietetici per contrastare disturbi sessuali in soggetti
US9084431B2 (en) * 2005-07-05 2015-07-21 Lonza Ltd. Spray-Drying process for producing a dry caritine powder or granulate
JP4915723B2 (ja) * 2006-03-13 2012-04-11 コスモ石油株式会社 アミノ酸リン酸類塩の製造方法
JP5069416B2 (ja) * 2006-03-15 2012-11-07 サントリーホールディングス株式会社 吸湿性の改善された飲食品用組成物
US8019451B2 (en) * 2006-11-22 2011-09-13 Target Brands, Inc. Financial transaction product with media player
CN101209975B (zh) 2006-12-29 2010-12-01 沈阳科硕营养科技有限公司 左旋肉碱富马酸钙及其制备方法与用途
KR100903549B1 (ko) * 2008-07-29 2009-06-23 주식회사 카이로제닉스 균질한 결정성의 아세틸-ｌ-카르니틴과 티옥트산 칼륨염의 복합염, 이의 제조방법 및 이를 포함하는 약학적 조성물
CN101817759B (zh) * 2010-05-12 2013-06-05 天津天成制药有限公司 L-肉碱硝酸盐的制备方法
CA2954004C (en) 2014-07-03 2023-10-10 NAN Global, LLC Methods and compositions for treating obesity, preventing weight gain, promoting weight loss, promoting slimming, or treating or preventing the development of diabetes
WO2017105090A1 (ko) * 2015-12-14 2017-06-22 제이투에이치바이오텍 (주) 오로트산 l-카르니틴의 결정질 다형체, 이의 제조방법 또는 용도
CN106045919B (zh) * 2016-07-07 2022-08-09 湖北楚维药业有限公司 一种左旋肉碱乳清酸盐的制备方法
CN106748845B (zh) * 2016-12-23 2018-11-20 东北制药集团股份有限公司 一种左旋肉碱盐微粉的制备方法
CN108383741A (zh) * 2018-03-16 2018-08-10 开原亨泰化工有限公司 一种制备左旋肉碱成盐的新方法
TWI710766B (zh) * 2018-08-13 2020-11-21 國立臺灣大學 使用口服肉鹼耐量試驗以測定一個體內氧化三甲胺產能之檢測方法

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Publication number Priority date Publication date Assignee Title
GB1153640A (en) * 1967-04-10 1969-05-29 Soc D Etudes Prod Chimique A Carnitin Salt
FR2529545B1 (fr) * 1982-07-02 1985-05-31 Sanofi Sa Nouveaux sels de carnitine ainsi que leur procede de preparation

Also Published As

Publication number Publication date
DK609984A (da) 1985-06-29
US4602039A (en) 1986-07-22
DK164543B (da) 1992-07-13
KR850004580A (ko) 1985-07-25
CA1252098A (en) 1989-04-04
EP0150688B1 (en) 1987-04-22
EP0150688A1 (en) 1985-08-07
GR82612B (en) 1985-05-02
DK609984D0 (da) 1984-12-19
ES8601856A1 (es) 1985-11-16
DE3463261D1 (en) 1987-05-27
KR900003020B1 (ko) 1990-05-04
IE843233L (en) 1985-06-28
ES539072A0 (es) 1985-11-16
IE57942B1 (en) 1993-05-19

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