DK1621633T3 - Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase - Google Patents
Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferaseInfo
- Publication number
- DK1621633T3 DK1621633T3 DK05108014.1T DK05108014T DK1621633T3 DK 1621633 T3 DK1621633 T3 DK 1621633T3 DK 05108014 T DK05108014 T DK 05108014T DK 1621633 T3 DK1621633 T3 DK 1621633T3
- Authority
- DK
- Denmark
- Prior art keywords
- plants
- xylosyltransferase
- beta
- glycoproteins produced
- suppressed expression
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title abstract 5
- 108090000288 Glycoproteins Proteins 0.000 title abstract 5
- 108010044310 beta 1,2-xylosyltransferase Proteins 0.000 title 1
- 102000003839 Human Proteins Human genes 0.000 abstract 2
- 108090000144 Human Proteins Proteins 0.000 abstract 2
- 108010065282 UDP xylose-protein xylosyltransferase Proteins 0.000 abstract 1
- 102000010199 Xylosyltransferases Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 125000000969 xylosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)CO1)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/02038—Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01024—Alpha-mannosidase (3.2.1.24)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0035500A AT409381B (de) | 2000-03-03 | 2000-03-03 | Xylosyltransferase-gen |
| EP01919367.1A EP1263968B2 (en) | 2000-03-03 | 2001-03-02 | Beta 1, 2-xylosyltransferase-gene from arabidopsis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1621633T3 true DK1621633T3 (da) | 2014-05-19 |
Family
ID=3672559
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05108014.1T DK1621633T3 (da) | 2000-03-03 | 2001-03-02 | Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase |
| DK01919367.1T DK1263968T4 (da) | 2000-03-03 | 2001-03-02 | Beta 1,2-xylosyltransferasegen fra arabidopsis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01919367.1T DK1263968T4 (da) | 2000-03-03 | 2001-03-02 | Beta 1,2-xylosyltransferasegen fra arabidopsis |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7205137B2 (enExample) |
| EP (2) | EP1621633B1 (enExample) |
| JP (2) | JP5279976B2 (enExample) |
| KR (5) | KR100859919B1 (enExample) |
| AT (2) | AT409381B (enExample) |
| AU (1) | AU781010B2 (enExample) |
| CA (1) | CA2402015C (enExample) |
| DE (1) | DE60115863T3 (enExample) |
| DK (2) | DK1621633T3 (enExample) |
| ES (2) | ES2460672T3 (enExample) |
| PT (1) | PT1621633E (enExample) |
| WO (1) | WO2001064901A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL143641A0 (en) | 1998-12-09 | 2002-04-21 | A method for manufacturing glycoproteins having human-type glycosylation | |
| DE60035285T2 (de) | 1999-10-26 | 2008-02-21 | Plant Research International B.V. | Glykolisierung des säugetiertyps in pflanzen |
| WO2002057468A2 (en) | 2001-01-19 | 2002-07-25 | The Dow Chemical Company | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| JP4532118B2 (ja) | 2002-03-19 | 2010-08-25 | スティヒティング ディーンスト ランドバウクンディフ オンデルズーク | 植物体内のグリカンプロセシングの最適化 |
| EP2319934B1 (en) | 2002-03-19 | 2015-09-02 | Stichting Dienst Landbouwkundig Onderzoek | GnTIII (UDP-N-acetylglucosamine:Beta -D mannoside Beta (1,4)-N-acetylglucosaminyltransferase III) expression in plants. |
| CL2003002461A1 (es) | 2002-11-27 | 2005-01-07 | Dow Chemical Company Agroscien | Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas. |
| DE60326716D1 (de) | 2003-08-11 | 2009-04-30 | Greenovation Biotech Gmbh | Promoter Sequenzen aus Moos und dessen Verwendung |
| AU2007205939B2 (en) | 2006-01-17 | 2012-12-13 | Synthon Biopharmaceuticals B.V. | Compositions and methods for humanization and optimization of N-glycans in plants |
| US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
| CA2646583A1 (en) * | 2006-03-23 | 2007-09-27 | Bayer Bioscience N.V. | Novel nucleotide sequences encoding nicotiana beta-1,2-xylosyltransferase |
| EP2535418B1 (en) | 2007-04-17 | 2016-03-30 | Stichting Dienst Landbouwkundig Onderzoek | Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases |
| WO2008148223A1 (en) | 2007-06-07 | 2008-12-11 | Agriculture And Agri-Food Canada | Nanocarrier based plant transfection and transduction |
| EP2789686A1 (en) | 2013-04-11 | 2014-10-15 | Greenovation Biotech GmbH | Expression of phosphorylated glycoproteins in plants |
| JP6934666B2 (ja) * | 2018-01-18 | 2021-09-15 | 国立研究開発法人産業技術総合研究所 | 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法 |
| EP3871687A1 (en) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzyme replacement therapy for treating pompe disease |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69631540T2 (de) * | 1995-11-23 | 2005-01-27 | Cancer Research Technology Ltd. | Materialien und methoden mit bezug zur identifizierung und sequenzierung des krebs-suszeptilitaetsgens brca2 und dessen anwendungen |
| AU1808699A (en) * | 1997-12-08 | 1999-06-28 | Board Of Trustees Of The University Of Arkansas, The | Purified beta1,2-xylosyltransferase and uses thereof |
| DE19754622A1 (de) * | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
| NZ505252A (en) * | 1997-12-19 | 2002-12-20 | Upjohn Co | Human sel-10 polypeptides and polynucleotides that encode them |
| US6207811B1 (en) * | 1998-03-18 | 2001-03-27 | Karl Tryggvason | Nephrin gene and protein |
| JP4351807B2 (ja) * | 1998-08-11 | 2009-10-28 | ダーウィン・ディスカバリー・リミテッド | マウスのｓｃｕｒｆｙの表現型を引き起こす遺伝子およびそのヒトのオルソログの同定 |
| EP1033405A3 (en) | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
| BR0014945A (pt) * | 1999-10-21 | 2004-08-31 | Monsanto Co | Modificação pós-traducional de proteìnas recombinantes produzidas em plantas |
-
2000
- 2000-03-03 AT AT0035500A patent/AT409381B/de not_active IP Right Cessation
-
2001
- 2001-03-02 KR KR1020077011024A patent/KR100859919B1/ko not_active Expired - Lifetime
- 2001-03-02 KR KR1020027011341A patent/KR100861437B1/ko not_active Expired - Lifetime
- 2001-03-02 EP EP05108014.1A patent/EP1621633B1/en not_active Expired - Lifetime
- 2001-03-02 KR KR1020107023909A patent/KR101185123B1/ko not_active Expired - Lifetime
- 2001-03-02 WO PCT/EP2001/002352 patent/WO2001064901A1/en not_active Ceased
- 2001-03-02 ES ES05108014.1T patent/ES2460672T3/es not_active Expired - Lifetime
- 2001-03-02 ES ES01919367.1T patent/ES2252208T5/es not_active Expired - Lifetime
- 2001-03-02 AU AU46495/01A patent/AU781010B2/en not_active Expired
- 2001-03-02 CA CA2402015A patent/CA2402015C/en not_active Expired - Lifetime
- 2001-03-02 AT AT01919367T patent/ATE312931T1/de active
- 2001-03-02 DK DK05108014.1T patent/DK1621633T3/da active
- 2001-03-02 EP EP01919367.1A patent/EP1263968B2/en not_active Expired - Lifetime
- 2001-03-02 DE DE60115863.6T patent/DE60115863T3/de not_active Expired - Lifetime
- 2001-03-02 PT PT51080141T patent/PT1621633E/pt unknown
- 2001-03-02 DK DK01919367.1T patent/DK1263968T4/da active
- 2001-03-02 JP JP2001563590A patent/JP5279976B2/ja not_active Expired - Lifetime
- 2001-03-02 KR KR1020097019435A patent/KR20090101981A/ko not_active Ceased
- 2001-03-02 US US10/220,467 patent/US7205137B2/en not_active Expired - Lifetime
- 2001-03-02 KR KR1020087019207A patent/KR20080077296A/ko not_active Ceased
-
2007
- 2007-03-12 US US11/684,898 patent/US20070186311A1/en not_active Abandoned
-
2012
- 2012-03-23 US US13/428,777 patent/US20120331578A1/en not_active Abandoned
-
2013
- 2013-01-16 JP JP2013005404A patent/JP2013116113A/ja active Pending
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