KR100859919B1 - 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자 - Google Patents

아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자 Download PDF

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KR100859919B1
KR100859919B1 KR1020077011024A KR20077011024A KR100859919B1 KR 100859919 B1 KR100859919 B1 KR 100859919B1 KR 1020077011024 A KR1020077011024 A KR 1020077011024A KR 20077011024 A KR20077011024 A KR 20077011024A KR 100859919 B1 KR100859919 B1 KR 100859919B1
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sequence
xylsilyltransferase
dna
plant
glycoprotein
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KR20070058018A (ko
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요세프 그뢰슬
리차드 스트라세르
잔 무카
루카스 마크
프리드리히 알트만
아인 비. 윌슨
헤르타 스타인켈너
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요세프 그뢰슬
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/02Pentosyltransferases (2.4.2)
    • C12Y204/02038Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024Alpha-mannosidase (3.2.1.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105Alpha-N-acetylglucosaminidase (3.2.1.50)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052Beta-N-acetylhexosaminidase (3.2.1.52)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1020077011024A 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자 Expired - Lifetime KR100859919B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA355/2000 2000-03-03
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020027011341A Division KR100861437B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자

Publications (2)

Publication Number Publication Date
KR20070058018A KR20070058018A (ko) 2007-06-07
KR100859919B1 true KR100859919B1 (ko) 2008-09-23

Family

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Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020077011024A Expired - Lifetime KR100859919B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
KR1020027011341A Expired - Lifetime KR100861437B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
KR1020107023909A Expired - Lifetime KR101185123B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020097019435A Ceased KR20090101981A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020087019207A Ceased KR20080077296A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자

Family Applications After (4)

Application Number Title Priority Date Filing Date
KR1020027011341A Expired - Lifetime KR100861437B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
KR1020107023909A Expired - Lifetime KR101185123B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020097019435A Ceased KR20090101981A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020087019207A Ceased KR20080077296A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자

Country Status (12)

Country Link
US (3) US7205137B2 (enExample)
EP (2) EP1621633B1 (enExample)
JP (2) JP5279976B2 (enExample)
KR (5) KR100859919B1 (enExample)
AT (2) AT409381B (enExample)
AU (1) AU781010B2 (enExample)
CA (1) CA2402015C (enExample)
DE (1) DE60115863T3 (enExample)
DK (2) DK1621633T3 (enExample)
ES (2) ES2460672T3 (enExample)
PT (1) PT1621633E (enExample)
WO (1) WO2001064901A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL143641A0 (en) 1998-12-09 2002-04-21 A method for manufacturing glycoproteins having human-type glycosylation
DE60035285T2 (de) 1999-10-26 2008-02-21 Plant Research International B.V. Glykolisierung des säugetiertyps in pflanzen
WO2002057468A2 (en) 2001-01-19 2002-07-25 The Dow Chemical Company Method for secretory production of glycoprotein having human-type sugar chain using plant cell
JP4532118B2 (ja) 2002-03-19 2010-08-25 スティヒティング ディーンスト ランドバウクンディフ オンデルズーク 植物体内のグリカンプロセシングの最適化
EP2319934B1 (en) 2002-03-19 2015-09-02 Stichting Dienst Landbouwkundig Onderzoek GnTIII (UDP-N-acetylglucosamine:Beta -D mannoside Beta (1,4)-N-acetylglucosaminyltransferase III) expression in plants.
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
DE60326716D1 (de) 2003-08-11 2009-04-30 Greenovation Biotech Gmbh Promoter Sequenzen aus Moos und dessen Verwendung
AU2007205939B2 (en) 2006-01-17 2012-12-13 Synthon Biopharmaceuticals B.V. Compositions and methods for humanization and optimization of N-glycans in plants
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
CA2646583A1 (en) * 2006-03-23 2007-09-27 Bayer Bioscience N.V. Novel nucleotide sequences encoding nicotiana beta-1,2-xylosyltransferase
EP2535418B1 (en) 2007-04-17 2016-03-30 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
WO2008148223A1 (en) 2007-06-07 2008-12-11 Agriculture And Agri-Food Canada Nanocarrier based plant transfection and transduction
EP2789686A1 (en) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression of phosphorylated glycoproteins in plants
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
EP3871687A1 (en) 2020-02-27 2021-09-01 eleva GmbH Enzyme replacement therapy for treating pompe disease

Citations (2)

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Publication number Priority date Publication date Assignee Title
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF
WO2001029242A2 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants

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DE69631540T2 (de) * 1995-11-23 2005-01-27 Cancer Research Technology Ltd. Materialien und methoden mit bezug zur identifizierung und sequenzierung des krebs-suszeptilitaetsgens brca2 und dessen anwendungen
DE19754622A1 (de) * 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
NZ505252A (en) * 1997-12-19 2002-12-20 Upjohn Co Human sel-10 polypeptides and polynucleotides that encode them
US6207811B1 (en) * 1998-03-18 2001-03-27 Karl Tryggvason Nephrin gene and protein
JP4351807B2 (ja) * 1998-08-11 2009-10-28 ダーウィン・ディスカバリー・リミテッド マウスのscurfyの表現型を引き起こす遺伝子およびそのヒトのオルソログの同定
EP1033405A3 (en) 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF
WO2001029242A2 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants

Also Published As

Publication number Publication date
KR20090101981A (ko) 2009-09-29
KR20070058018A (ko) 2007-06-07
US20040121325A1 (en) 2004-06-24
DE60115863T3 (de) 2015-01-22
ES2252208T3 (es) 2006-05-16
ATE312931T1 (de) 2005-12-15
US20120331578A1 (en) 2012-12-27
KR100861437B1 (ko) 2008-10-02
ATA3552000A (de) 2001-12-15
EP1263968A1 (en) 2002-12-11
ES2460672T3 (es) 2014-05-14
JP5279976B2 (ja) 2013-09-04
AT409381B (de) 2002-07-25
EP1621633A3 (en) 2006-02-08
KR20030030987A (ko) 2003-04-18
JP2004500096A (ja) 2004-01-08
DE60115863T2 (de) 2006-08-10
AU781010B2 (en) 2005-04-28
CA2402015A1 (en) 2001-09-07
KR20080077296A (ko) 2008-08-21
KR20100119005A (ko) 2010-11-08
US20070186311A1 (en) 2007-08-09
AU4649501A (en) 2001-09-12
EP1263968B2 (en) 2014-09-10
PT1621633E (pt) 2014-07-18
EP1621633A2 (en) 2006-02-01
DK1263968T3 (da) 2006-05-01
EP1621633B1 (en) 2014-04-16
CA2402015C (en) 2012-07-17
DK1263968T4 (da) 2014-11-03
KR101185123B1 (ko) 2012-09-21
ES2252208T5 (es) 2014-11-04
US7205137B2 (en) 2007-04-17
JP2013116113A (ja) 2013-06-13
DK1621633T3 (da) 2014-05-19
EP1263968B1 (en) 2005-12-14
DE60115863D1 (de) 2006-01-19
WO2001064901A1 (en) 2001-09-07

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