ES2460672T3 - Glicoproteínas producidas en plantas con una expresión suprimida de la beta 1,2-xilosiltransferasa - Google Patents
Glicoproteínas producidas en plantas con una expresión suprimida de la beta 1,2-xilosiltransferasa Download PDFInfo
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- ES2460672T3 ES2460672T3 ES05108014.1T ES05108014T ES2460672T3 ES 2460672 T3 ES2460672 T3 ES 2460672T3 ES 05108014 T ES05108014 T ES 05108014T ES 2460672 T3 ES2460672 T3 ES 2460672T3
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- xylosyltransferase
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/02038—Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01024—Alpha-mannosidase (3.2.1.24)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
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- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
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|---|---|---|---|
| AT3552000 | 2000-03-03 | ||
| AT0035500A AT409381B (de) | 2000-03-03 | 2000-03-03 | Xylosyltransferase-gen |
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| ES2460672T3 true ES2460672T3 (es) | 2014-05-14 |
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| ES01919367.1T Expired - Lifetime ES2252208T5 (es) | 2000-03-03 | 2001-03-02 | Gen de beta 1,2 xilosil transferasa procedente de Arabidopsis |
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| ES01919367.1T Expired - Lifetime ES2252208T5 (es) | 2000-03-03 | 2001-03-02 | Gen de beta 1,2 xilosil transferasa procedente de Arabidopsis |
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| EP (2) | EP1621633B1 (enExample) |
| JP (2) | JP5279976B2 (enExample) |
| KR (5) | KR20080077296A (enExample) |
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| AU (1) | AU781010B2 (enExample) |
| CA (1) | CA2402015C (enExample) |
| DE (1) | DE60115863T3 (enExample) |
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| PT (1) | PT1621633E (enExample) |
| WO (1) | WO2001064901A1 (enExample) |
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| EP2264177B1 (en) | 1998-12-09 | 2015-09-30 | Phyton Holdings, LLC | Glycoproteins having human-type glycosylation |
| NZ518532A (en) | 1999-10-26 | 2004-02-27 | Plant Res Internat B | Transgenic plant expressing mammalian beta-1,4- galactosyltransferase |
| EP1356068B1 (en) | 2001-01-19 | 2014-10-29 | Phyton Holdings, LLC | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| AU2003219402B2 (en) | 2002-03-19 | 2008-05-08 | Stichting Dienst Landbouwkundig Onderzoek | GnTIII (UDP-n-acethylglucosamine:beta-D mannoside beta (1,4)-N-acethylglucosaminy ltransferase III) expression in plants |
| JP4532118B2 (ja) | 2002-03-19 | 2010-08-25 | スティヒティング ディーンスト ランドバウクンディフ オンデルズーク | 植物体内のグリカンプロセシングの最適化 |
| CL2003002461A1 (es) | 2002-11-27 | 2005-01-07 | Dow Chemical Company Agroscien | Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas. |
| EP1510584B1 (en) | 2003-08-11 | 2009-03-18 | Greenovation Biotech GmbH | Expression promoting sequences from mosses and their uses |
| WO2007084926A2 (en) * | 2006-01-17 | 2007-07-26 | Biolex Therapeutics, Inc. | Compositions and methods for humanization and optimization of n-glycans in plants |
| US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
| KR20090007354A (ko) * | 2006-03-23 | 2009-01-16 | 바이엘 바이오사이언스 엔.브이. | 니코티아나 베타-1,2-크실로실트랜스퍼레이즈를 코딩하는 신규 뉴클레오티드 서열 |
| DK2535418T3 (en) | 2007-04-17 | 2016-07-25 | Stichting Dienst Landbouwkundig Onderzoek | Mammalian TYPE glycosylation I PLANTS BY EXPRESSION OF NON-mammalian glycosyltransferases |
| WO2008148223A1 (en) | 2007-06-07 | 2008-12-11 | Agriculture And Agri-Food Canada | Nanocarrier based plant transfection and transduction |
| EP2789686A1 (en) | 2013-04-11 | 2014-10-15 | Greenovation Biotech GmbH | Expression of phosphorylated glycoproteins in plants |
| JP6934666B2 (ja) * | 2018-01-18 | 2021-09-15 | 国立研究開発法人産業技術総合研究所 | 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法 |
| EP3871687A1 (en) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzyme replacement therapy for treating pompe disease |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997019110A1 (en) * | 1995-11-23 | 1997-05-29 | Cancer Research Campaign Technology Limited | Materials and methods relating to the identification and sequencing of the brca2 cancer susceptibility gene and uses thereof |
| US6168937B1 (en) * | 1997-12-08 | 2001-01-02 | Alan D. Elbein | Purified β1,2-xylosyltransferase and uses thereof |
| DE19754622A1 (de) † | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
| JP2003520012A (ja) * | 1997-12-19 | 2003-07-02 | ファルマシア・アンド・アップジョン・カンパニー | ヒトＳｅｌ−１０ポリペプチドおよびそれをコードするポリヌクレオチド |
| US6207811B1 (en) * | 1998-03-18 | 2001-03-27 | Karl Tryggvason | Nephrin gene and protein |
| ATE495255T1 (de) * | 1998-08-11 | 2011-01-15 | Darwin Discovery Ltd | Identifikation des gens das zum schorfigen phenotyp der maus führt, sowie seines menschlichen orthologs |
| EP1033405A3 (en) | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
| WO2001029242A2 (en) | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
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2000
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2001
- 2001-03-02 JP JP2001563590A patent/JP5279976B2/ja not_active Expired - Lifetime
- 2001-03-02 KR KR1020087019207A patent/KR20080077296A/ko not_active Ceased
- 2001-03-02 DK DK05108014.1T patent/DK1621633T3/da active
- 2001-03-02 DK DK01919367.1T patent/DK1263968T4/da active
- 2001-03-02 AT AT01919367T patent/ATE312931T1/de active
- 2001-03-02 CA CA2402015A patent/CA2402015C/en not_active Expired - Lifetime
- 2001-03-02 KR KR1020027011341A patent/KR100861437B1/ko not_active Expired - Lifetime
- 2001-03-02 KR KR1020097019435A patent/KR20090101981A/ko not_active Ceased
- 2001-03-02 WO PCT/EP2001/002352 patent/WO2001064901A1/en not_active Ceased
- 2001-03-02 KR KR1020077011024A patent/KR100859919B1/ko not_active Expired - Lifetime
- 2001-03-02 AU AU46495/01A patent/AU781010B2/en not_active Expired
- 2001-03-02 EP EP05108014.1A patent/EP1621633B1/en not_active Expired - Lifetime
- 2001-03-02 PT PT51080141T patent/PT1621633E/pt unknown
- 2001-03-02 ES ES05108014.1T patent/ES2460672T3/es not_active Expired - Lifetime
- 2001-03-02 DE DE60115863.6T patent/DE60115863T3/de not_active Expired - Lifetime
- 2001-03-02 KR KR1020107023909A patent/KR101185123B1/ko not_active Expired - Lifetime
- 2001-03-02 ES ES01919367.1T patent/ES2252208T5/es not_active Expired - Lifetime
- 2001-03-02 US US10/220,467 patent/US7205137B2/en not_active Expired - Lifetime
- 2001-03-02 EP EP01919367.1A patent/EP1263968B2/en not_active Expired - Lifetime
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2007
- 2007-03-12 US US11/684,898 patent/US20070186311A1/en not_active Abandoned
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2012
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2013
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