JP5279976B2 - アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子 - Google Patents

アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子 Download PDF

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JP5279976B2
JP5279976B2 JP2001563590A JP2001563590A JP5279976B2 JP 5279976 B2 JP5279976 B2 JP 5279976B2 JP 2001563590 A JP2001563590 A JP 2001563590A JP 2001563590 A JP2001563590 A JP 2001563590A JP 5279976 B2 JP5279976 B2 JP 5279976B2
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Prior art keywords
xylosyltransferase
sequence
dna molecule
dna
plant
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Expired - Lifetime
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Japanese (ja)
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JP2004500096A (ja
JP2004500096A5 (enExample
Inventor
ヨーゼフ・グレッスル
リヒャルト・シュトラッサー
ヤン・ムハ
ルーカス・マッハ
フリードリッヒ・アルトマン
イアン・ビー・ウィルソン
ヘルタ・シュタインケルナー
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Josef Gloessl
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Josef Gloessl
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/02Pentosyltransferases (2.4.2)
    • C12Y204/02038Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024Alpha-mannosidase (3.2.1.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105Alpha-N-acetylglucosaminidase (3.2.1.50)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052Beta-N-acetylhexosaminidase (3.2.1.52)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2001563590A 2000-03-03 2001-03-02 アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子 Expired - Lifetime JP5279976B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ATA355/2000 2000-03-03
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
PCT/EP2001/002352 WO2001064901A1 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013005404A Division JP2013116113A (ja) 2000-03-03 2013-01-16 アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子

Publications (3)

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JP2004500096A JP2004500096A (ja) 2004-01-08
JP2004500096A5 JP2004500096A5 (enExample) 2008-03-21
JP5279976B2 true JP5279976B2 (ja) 2013-09-04

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ID=3672559

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JP2001563590A Expired - Lifetime JP5279976B2 (ja) 2000-03-03 2001-03-02 アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子
JP2013005404A Pending JP2013116113A (ja) 2000-03-03 2013-01-16 アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子

Family Applications After (1)

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JP2013005404A Pending JP2013116113A (ja) 2000-03-03 2013-01-16 アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子

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US (3) US7205137B2 (enExample)
EP (2) EP1263968B2 (enExample)
JP (2) JP5279976B2 (enExample)
KR (5) KR20080077296A (enExample)
AT (2) AT409381B (enExample)
AU (1) AU781010B2 (enExample)
CA (1) CA2402015C (enExample)
DE (1) DE60115863T3 (enExample)
DK (2) DK1263968T4 (enExample)
ES (2) ES2252208T5 (enExample)
PT (1) PT1621633E (enExample)
WO (1) WO2001064901A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2350063T3 (es) 1998-12-09 2011-01-17 Phyton Holdings, Llc Método para fabricación de glicoproteínas que tienen glicosilación de tipo humano.
NZ518532A (en) 1999-10-26 2004-02-27 Plant Res Internat B Transgenic plant expressing mammalian beta-1,4- galactosyltransferase
CA2434364C (en) 2001-01-19 2013-03-19 The Dow Chemical Company Method for secretory production of glycoprotein having human-type sugar chain using plant cell
CA2799805C (en) 2002-03-19 2016-05-17 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
WO2003078614A2 (en) 2002-03-19 2003-09-25 Plant Research International B.V. Gntiii (udp-n-acethylglucosamine:beta-d mannoside beta (1,4)-n-acethylglucosaminy ltransferase iii) expression in plants
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
ATE426033T1 (de) 2003-08-11 2009-04-15 Greenovation Biotech Gmbh Promoter sequenzen aus moos und dessen verwendung
MX2008009220A (es) * 2006-01-17 2008-10-10 Biolex Therapeutics Inc Composiciones y metodos para la humanizacion y optimizacion de n-glicanos en plantas.
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
AU2007229061A1 (en) * 2006-03-23 2007-09-27 Bayer Bioscience N.V. Novel nucleotide sequences encoding nicotiana beta-1,2-xylosyltransferase
CN101702919B (zh) 2007-04-17 2014-08-13 基金会农业研究服务中心 植物通过表达非哺乳动物糖基转移酶而表现出哺乳动物类型的糖基化作用
CA2693525C (en) 2007-06-07 2020-09-29 Agriculture And Agri-Food Canada Nanocarrier based transfection and transduction of plant gametophytic cells
EP2789686A1 (en) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression of phosphorylated glycoproteins in plants
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
EP3871687A1 (en) 2020-02-27 2021-09-01 eleva GmbH Enzyme replacement therapy for treating pompe disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE259378T1 (de) * 1995-11-23 2004-02-15 Cancer Res Campaign Tech Materialien und methoden mit bezug zur identifizierung und sequenzierung des krebs- suszeptilitaetsgens brca2 und dessen anwendungen
AU1808699A (en) * 1997-12-08 1999-06-28 Board Of Trustees Of The University Of Arkansas, The Purified beta1,2-xylosyltransferase and uses thereof
DE19754622A1 (de) 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
CA2309391A1 (en) * 1997-12-19 1999-07-01 Pharmacia & Upjohn Company Human sel-10 polypeptides and polynucleotides that encode them
US6207811B1 (en) * 1998-03-18 2001-03-27 Karl Tryggvason Nephrin gene and protein
AU5559499A (en) * 1998-08-11 2000-03-06 Darwin Discovery Limited Identification of the gene causing the mouse scurfy phenotype and its human ortholog
EP1033405A3 (en) * 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
BR0014945A (pt) * 1999-10-21 2004-08-31 Monsanto Co Modificação pós-traducional de proteìnas recombinantes produzidas em plantas

Also Published As

Publication number Publication date
KR20080077296A (ko) 2008-08-21
KR20090101981A (ko) 2009-09-29
PT1621633E (pt) 2014-07-18
KR20070058018A (ko) 2007-06-07
JP2004500096A (ja) 2004-01-08
KR100859919B1 (ko) 2008-09-23
US20120331578A1 (en) 2012-12-27
KR100861437B1 (ko) 2008-10-02
DE60115863T3 (de) 2015-01-22
CA2402015A1 (en) 2001-09-07
DK1263968T4 (da) 2014-11-03
WO2001064901A1 (en) 2001-09-07
EP1263968B2 (en) 2014-09-10
DE60115863D1 (de) 2006-01-19
DK1263968T3 (da) 2006-05-01
DK1621633T3 (da) 2014-05-19
CA2402015C (en) 2012-07-17
EP1621633A2 (en) 2006-02-01
US20070186311A1 (en) 2007-08-09
AU4649501A (en) 2001-09-12
ATE312931T1 (de) 2005-12-15
KR101185123B1 (ko) 2012-09-21
ES2252208T3 (es) 2006-05-16
US7205137B2 (en) 2007-04-17
EP1621633B1 (en) 2014-04-16
KR20100119005A (ko) 2010-11-08
AU781010B2 (en) 2005-04-28
JP2013116113A (ja) 2013-06-13
EP1263968B1 (en) 2005-12-14
EP1263968A1 (en) 2002-12-11
US20040121325A1 (en) 2004-06-24
ATA3552000A (de) 2001-12-15
DE60115863T2 (de) 2006-08-10
AT409381B (de) 2002-07-25
KR20030030987A (ko) 2003-04-18
EP1621633A3 (en) 2006-02-08
ES2252208T5 (es) 2014-11-04
ES2460672T3 (es) 2014-05-14

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