JP2004500096A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004500096A5 JP2004500096A5 JP2001563590A JP2001563590A JP2004500096A5 JP 2004500096 A5 JP2004500096 A5 JP 2004500096A5 JP 2001563590 A JP2001563590 A JP 2001563590A JP 2001563590 A JP2001563590 A JP 2001563590A JP 2004500096 A5 JP2004500096 A5 JP 2004500096A5
- Authority
- JP
- Japan
- Prior art keywords
- dna molecule
- plant
- xylosyltransferase
- sequence
- glycoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004414 DNA Proteins 0.000 description 23
- 102000053602 DNA Human genes 0.000 description 20
- 102000003886 Glycoproteins Human genes 0.000 description 12
- 108090000288 Glycoproteins Proteins 0.000 description 12
- 108010044310 beta 1,2-xylosyltransferase Proteins 0.000 description 12
- 238000004519 manufacturing process Methods 0.000 description 12
- 238000000034 method Methods 0.000 description 11
- 108090000994 Catalytic RNA Proteins 0.000 description 3
- 102000053642 Catalytic RNA Human genes 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 108091092562 ribozyme Proteins 0.000 description 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 108010029485 Protein Isoforms Proteins 0.000 description 2
- 102000001708 Protein Isoforms Human genes 0.000 description 2
- 150000001720 carbohydrates Chemical group 0.000 description 2
- 238000001890 transfection Methods 0.000 description 2
- 238000000018 DNA microarray Methods 0.000 description 1
- 102100034343 Integrase Human genes 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 1
- 108010065282 UDP xylose-protein xylosyltransferase Proteins 0.000 description 1
- DQQDLYVHOTZLOR-OCIMBMBZSA-N UDP-alpha-D-xylose Chemical compound C([C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(=O)C=C1)=O)O)O)OP(O)(=O)OP(O)(=O)O[C@H]1OC[C@@H](O)[C@H](O)[C@H]1O DQQDLYVHOTZLOR-OCIMBMBZSA-N 0.000 description 1
- DQQDLYVHOTZLOR-UHFFFAOYSA-N UDP-alpha-D-xylose Natural products O1C(N2C(NC(=O)C=C2)=O)C(O)C(O)C1COP(O)(=O)OP(O)(=O)OC1OCC(O)C(O)C1O DQQDLYVHOTZLOR-UHFFFAOYSA-N 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 102000010199 Xylosyltransferases Human genes 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0035500A AT409381B (de) | 2000-03-03 | 2000-03-03 | Xylosyltransferase-gen |
| ATA355/2000 | 2000-03-03 | ||
| PCT/EP2001/002352 WO2001064901A1 (en) | 2000-03-03 | 2001-03-02 | Beta 1, 2-xylosyltransferase-gene from arabidopsis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013005404A Division JP2013116113A (ja) | 2000-03-03 | 2013-01-16 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004500096A JP2004500096A (ja) | 2004-01-08 |
| JP2004500096A5 true JP2004500096A5 (enExample) | 2008-03-21 |
| JP5279976B2 JP5279976B2 (ja) | 2013-09-04 |
Family
ID=3672559
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001563590A Expired - Lifetime JP5279976B2 (ja) | 2000-03-03 | 2001-03-02 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
| JP2013005404A Pending JP2013116113A (ja) | 2000-03-03 | 2013-01-16 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013005404A Pending JP2013116113A (ja) | 2000-03-03 | 2013-01-16 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7205137B2 (enExample) |
| EP (2) | EP1263968B2 (enExample) |
| JP (2) | JP5279976B2 (enExample) |
| KR (5) | KR20090101981A (enExample) |
| AT (2) | AT409381B (enExample) |
| AU (1) | AU781010B2 (enExample) |
| CA (1) | CA2402015C (enExample) |
| DE (1) | DE60115863T3 (enExample) |
| DK (2) | DK1263968T4 (enExample) |
| ES (2) | ES2252208T5 (enExample) |
| PT (1) | PT1621633E (enExample) |
| WO (1) | WO2001064901A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1137789T3 (da) | 1998-12-09 | 2010-11-08 | Phyton Holdings Llc | Fremgangsmåde til fremstilling af et glycoprotein med glycosylering af human type |
| DK1772518T3 (da) | 1999-10-26 | 2010-11-22 | Stichting Dienst Landbouwkundi | Pattedyrsagtig glykosylering i planter |
| US20040214273A1 (en) | 2001-01-19 | 2004-10-28 | Kazuhito Fujiyama | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| WO2003078614A2 (en) | 2002-03-19 | 2003-09-25 | Plant Research International B.V. | Gntiii (udp-n-acethylglucosamine:beta-d mannoside beta (1,4)-n-acethylglucosaminy ltransferase iii) expression in plants |
| KR101060361B1 (ko) | 2002-03-19 | 2011-08-29 | 스티칭 디엔스트 랜드보위쿤디그 온데조에크 | 식물에서 글리칸 프로세싱의 최적화 |
| AR042145A1 (es) | 2002-11-27 | 2005-06-08 | Dow Agrociences Llc | Produccion de inmunoglobulinas en plantas con una fucocilacion reducida |
| ATE426033T1 (de) | 2003-08-11 | 2009-04-15 | Greenovation Biotech Gmbh | Promoter sequenzen aus moos und dessen verwendung |
| DK1974040T3 (da) | 2006-01-17 | 2012-12-17 | Synthon Biopharmaceuticals Bv | Sammensætninger og fremgangsmåder til humanisering og optimering af N-glycanet i planter. |
| US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
| JP2009529898A (ja) * | 2006-03-23 | 2009-08-27 | バイエル・バイオサイエンス・エヌ・ヴェー | Ｎｉｃｏｔｉａｎａβ−１，２−キシロシルトランスフェラーゼをコードする新規なヌクレオチド配列 |
| CN104195166B (zh) | 2007-04-17 | 2017-01-11 | 基金会农业研究服务中心 | 植物通过表达非哺乳动物糖基转移酶而表现出哺乳动物类型的糖基化作用 |
| BRPI0814244B1 (pt) | 2007-06-07 | 2018-10-09 | Agriculture And Agri Food Canada | método para obtenção de uma planta geneticamente engenheirada |
| EP2789686A1 (en) | 2013-04-11 | 2014-10-15 | Greenovation Biotech GmbH | Expression of phosphorylated glycoproteins in plants |
| JP6934666B2 (ja) * | 2018-01-18 | 2021-09-15 | 国立研究開発法人産業技術総合研究所 | 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法 |
| EP3871687A1 (en) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzyme replacement therapy for treating pompe disease |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0858467B1 (en) * | 1995-11-23 | 2004-02-11 | Cancer Research Campaign Technology Limited | Materials and methods relating to the identification and sequencing of the brca2 cancer susceptibility gene and uses thereof |
| WO1999029835A1 (en) * | 1997-12-08 | 1999-06-17 | Board Of Trustees Of The University Of Arkansas | PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF |
| DE19754622A1 (de) † | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
| DE69830074D1 (de) * | 1997-12-19 | 2005-06-09 | Upjohn Co | Humane sel-10 polypeptiden und dafur kodierende polynukleotiden |
| US6207811B1 (en) * | 1998-03-18 | 2001-03-27 | Karl Tryggvason | Nephrin gene and protein |
| CA2339409A1 (en) * | 1998-08-11 | 2000-02-24 | Darwin Discovery Ltd. | Identification of the gene causing the mouse scurfy phenotype and its human ortholog |
| EP1033405A3 (en) * | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
| CA2388432A1 (en) | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
-
2000
- 2000-03-03 AT AT0035500A patent/AT409381B/de not_active IP Right Cessation
-
2001
- 2001-03-02 WO PCT/EP2001/002352 patent/WO2001064901A1/en not_active Ceased
- 2001-03-02 ES ES01919367.1T patent/ES2252208T5/es not_active Expired - Lifetime
- 2001-03-02 KR KR1020097019435A patent/KR20090101981A/ko not_active Ceased
- 2001-03-02 JP JP2001563590A patent/JP5279976B2/ja not_active Expired - Lifetime
- 2001-03-02 DE DE60115863.6T patent/DE60115863T3/de not_active Expired - Lifetime
- 2001-03-02 EP EP01919367.1A patent/EP1263968B2/en not_active Expired - Lifetime
- 2001-03-02 DK DK01919367.1T patent/DK1263968T4/da active
- 2001-03-02 KR KR1020107023909A patent/KR101185123B1/ko not_active Expired - Lifetime
- 2001-03-02 AU AU46495/01A patent/AU781010B2/en not_active Expired
- 2001-03-02 ES ES05108014.1T patent/ES2460672T3/es not_active Expired - Lifetime
- 2001-03-02 KR KR1020027011341A patent/KR100861437B1/ko not_active Expired - Lifetime
- 2001-03-02 DK DK05108014.1T patent/DK1621633T3/da active
- 2001-03-02 AT AT01919367T patent/ATE312931T1/de active
- 2001-03-02 PT PT51080141T patent/PT1621633E/pt unknown
- 2001-03-02 KR KR1020077011024A patent/KR100859919B1/ko not_active Expired - Lifetime
- 2001-03-02 US US10/220,467 patent/US7205137B2/en not_active Expired - Lifetime
- 2001-03-02 EP EP05108014.1A patent/EP1621633B1/en not_active Expired - Lifetime
- 2001-03-02 CA CA2402015A patent/CA2402015C/en not_active Expired - Lifetime
- 2001-03-02 KR KR1020087019207A patent/KR20080077296A/ko not_active Ceased
-
2007
- 2007-03-12 US US11/684,898 patent/US20070186311A1/en not_active Abandoned
-
2012
- 2012-03-23 US US13/428,777 patent/US20120331578A1/en not_active Abandoned
-
2013
- 2013-01-16 JP JP2013005404A patent/JP2013116113A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004500096A5 (enExample) | ||
| Aikawa et al. | Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAcN-Deacetylase/N-Sulfotransferase family | |
| Taylor et al. | The irregular xylem3 locus of Arabidopsis encodes a cellulose synthase required for secondary cell wall synthesis | |
| Sauer et al. | AtSUC8 and AtSUC9 encode functional sucrose transporters, but the closely related AtSUC6 and AtSUC7 genes encode aberrant proteins in different Arabidopsis ecotypes | |
| Schmidt | LINEs, SINEs and repetitive DNA: non-LTR retrotransposons in plant genomes | |
| JP2002536978A5 (enExample) | ||
| Berkhout et al. | Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus | |
| CN113373130A (zh) | Cas12蛋白、含有Cas12蛋白的基因编辑系统及应用 | |
| Driscoll et al. | Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA | |
| ATA27099A (de) | Fucosyltransferase-gen | |
| JP2002524052A5 (enExample) | ||
| CN110331136B (zh) | 一种末端脱氧核糖核苷转移酶变体及其应用 | |
| CA2402015A1 (en) | Beta 1, 2-xylosyltransferase-gene from arabidopsis | |
| CN101613680B (zh) | 莫洛尼氏鼠白血病病毒逆转录酶突变体及其表达方法和应用 | |
| Saab-Rincón et al. | Different strategies to recover the activity of monomeric triosephosphate isomerase by directed evolution | |
| Matsubayashi et al. | Identification and functional characterization of phytosulfokine receptor using a ligand‐based approach | |
| US7150981B2 (en) | Sulfate transferase and DNA encoding this enzyme | |
| Lamhonwah et al. | Correction of the metabolic defect in propionic acidemia fibroblasts by microinjection of a full-length cDNA or RNA transcript encoding the propionyl-CoA carboxylase β subunit | |
| JPWO2002000889A1 (ja) | 硫酸基転移酵素及び該酵素をコードするｄｎａ | |
| JP3688367B2 (ja) | 変異型ｄｎａポリメラーゼ | |
| CN114380918B (zh) | 一种目标rna单碱基编辑的系统和方法 | |
| CN120464610A (zh) | 胞嘧啶脱氨酶SvSddA、包含其的碱基编辑器及应用 | |
| CN120004994A (zh) | 一种胞嘧啶脱氨酶抑制剂SflSddi及其应用 | |
| WO2022050413A1 (ja) | 小型化シチジンデアミナーゼを含む二本鎖ｄｎａの改変用複合体 | |
| CN120591242A (zh) | 胞嘧啶脱氨酶AiSddA、包含其的碱基编辑器及应用 |