DK1606282T3 - Phenyl- og pyridylpipereidinye-derivater som modulatorer af glucosemetabolisme - Google Patents
Phenyl- og pyridylpipereidinye-derivater som modulatorer af glucosemetabolismeInfo
- Publication number
- DK1606282T3 DK1606282T3 DK04713803T DK04713803T DK1606282T3 DK 1606282 T3 DK1606282 T3 DK 1606282T3 DK 04713803 T DK04713803 T DK 04713803T DK 04713803 T DK04713803 T DK 04713803T DK 1606282 T3 DK1606282 T3 DK 1606282T3
- Authority
- DK
- Denmark
- Prior art keywords
- modulators
- derivatives
- pyridylpipereidinye
- phenyl
- glucose metabolism
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44978803P | 2003-02-24 | 2003-02-24 | |
| PCT/US2004/005555 WO2004076413A2 (en) | 2003-02-24 | 2004-02-23 | Phenyl- and pyridylpiperidine-derivatives as modulators of glucose metabolism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1606282T3 true DK1606282T3 (da) | 2009-03-16 |
Family
ID=32927568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04713803T DK1606282T3 (da) | 2003-02-24 | 2004-02-23 | Phenyl- og pyridylpipereidinye-derivater som modulatorer af glucosemetabolisme |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20070066590A1 (da) |
| EP (1) | EP1606282B1 (da) |
| JP (1) | JP2006518763A (da) |
| KR (1) | KR20050106033A (da) |
| CN (1) | CN1751038A (da) |
| AT (1) | ATE414076T1 (da) |
| AU (1) | AU2004215344B2 (da) |
| BR (1) | BRPI0407620A (da) |
| CA (1) | CA2515963A1 (da) |
| CY (1) | CY1108736T1 (da) |
| DE (1) | DE602004017703D1 (da) |
| DK (1) | DK1606282T3 (da) |
| EA (1) | EA200501348A1 (da) |
| ES (1) | ES2316964T3 (da) |
| HK (1) | HK1077305A1 (da) |
| MX (1) | MXPA05007614A (da) |
| PL (1) | PL378295A1 (da) |
| PT (1) | PT1606282E (da) |
| SI (1) | SI1606282T1 (da) |
| WO (1) | WO2004076413A2 (da) |
Families Citing this family (106)
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|---|---|---|---|---|
| FR2817257B1 (fr) | 2000-11-30 | 2009-03-20 | Sanofi Synthelabo | Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant |
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| AR045047A1 (es) * | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| JP5094398B2 (ja) | 2004-09-20 | 2012-12-12 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環式誘導体およびステアロイル−ＣｏＡデサチュラーゼのメディエータとしてのそれらの使用 |
| US7919496B2 (en) | 2004-09-20 | 2011-04-05 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes |
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| EP1807085B1 (en) | 2004-09-20 | 2013-08-21 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
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- 2004-02-23 PL PL378295A patent/PL378295A1/pl not_active Application Discontinuation
- 2004-02-23 EA EA200501348A patent/EA200501348A1/ru unknown
- 2004-02-23 EP EP04713803A patent/EP1606282B1/en not_active Expired - Lifetime
- 2004-02-23 US US10/546,665 patent/US20070066590A1/en not_active Abandoned
- 2004-02-23 ES ES04713803T patent/ES2316964T3/es not_active Expired - Lifetime
- 2004-02-23 DK DK04713803T patent/DK1606282T3/da active
- 2004-02-23 JP JP2006503856A patent/JP2006518763A/ja active Pending
- 2004-02-23 PT PT04713803T patent/PT1606282E/pt unknown
- 2004-02-23 WO PCT/US2004/005555 patent/WO2004076413A2/en active Application Filing
- 2004-02-23 BR BRPI0407620-6A patent/BRPI0407620A/pt not_active IP Right Cessation
- 2004-02-23 CN CNA2004800044127A patent/CN1751038A/zh active Pending
- 2004-02-23 MX MXPA05007614A patent/MXPA05007614A/es active IP Right Grant
- 2004-02-23 SI SI200431030T patent/SI1606282T1/sl unknown
- 2004-02-23 AT AT04713803T patent/ATE414076T1/de active
- 2004-02-23 CA CA002515963A patent/CA2515963A1/en not_active Withdrawn
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- 2004-02-23 DE DE602004017703T patent/DE602004017703D1/de not_active Expired - Lifetime
- 2004-02-23 KR KR1020057015582A patent/KR20050106033A/ko not_active Application Discontinuation
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2005
- 2005-12-28 HK HK05112041A patent/HK1077305A1/xx not_active IP Right Cessation
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2009
- 2009-01-29 CY CY20091100109T patent/CY1108736T1/el unknown
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| ES2316964T3 (es) | 2009-04-16 |
| AU2004215344A1 (en) | 2004-09-10 |
| HK1077305A1 (en) | 2006-02-10 |
| JP2006518763A (ja) | 2006-08-17 |
| CA2515963A1 (en) | 2004-09-10 |
| BRPI0407620A (pt) | 2006-02-21 |
| WO2004076413A2 (en) | 2004-09-10 |
| ATE414076T1 (de) | 2008-11-15 |
| KR20050106033A (ko) | 2005-11-08 |
| PT1606282E (pt) | 2009-02-10 |
| CY1108736T1 (el) | 2014-04-09 |
| PL378295A1 (pl) | 2006-03-20 |
| EP1606282A2 (en) | 2005-12-21 |
| DE602004017703D1 (de) | 2008-12-24 |
| EP1606282B1 (en) | 2008-11-12 |
| AU2004215344B2 (en) | 2010-06-24 |
| MXPA05007614A (es) | 2006-05-25 |
| US20070066590A1 (en) | 2007-03-22 |
| EA200501348A1 (ru) | 2006-02-24 |
| SI1606282T1 (sl) | 2009-04-30 |
| WO2004076413A3 (en) | 2004-12-02 |
| CN1751038A (zh) | 2006-03-22 |
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