DK158346C - Analogifremgangsmaade til fremstilling af 4-amino-5-alkylsulfonyl-o-anisamid-derivater samt 2-methoxy-4-amino-5-alkylsulfonylbenzoesyrer til anvendelse som mellemprodukter ved fremgangsmaaden - Google Patents

Analogifremgangsmaade til fremstilling af 4-amino-5-alkylsulfonyl-o-anisamid-derivater samt 2-methoxy-4-amino-5-alkylsulfonylbenzoesyrer til anvendelse som mellemprodukter ved fremgangsmaaden

Info

Publication number
DK158346C
DK158346C DK020979A DK20979A DK158346C DK 158346 C DK158346 C DK 158346C DK 020979 A DK020979 A DK 020979A DK 20979 A DK20979 A DK 20979A DK 158346 C DK158346 C DK 158346C
Authority
DK
Denmark
Prior art keywords
fruit
sodane
amino
intermediatric
acroduced
Prior art date
Application number
DK020979A
Other languages
Danish (da)
English (en)
Other versions
DK158346B (da
DK20979A (da
Inventor
Michel Thominet
Jacques Acher
Jean-Claude Monier
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of DK20979A publication Critical patent/DK20979A/da
Publication of DK158346B publication Critical patent/DK158346B/da
Application granted granted Critical
Publication of DK158346C publication Critical patent/DK158346C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DK020979A 1978-01-20 1979-01-18 Analogifremgangsmaade til fremstilling af 4-amino-5-alkylsulfonyl-o-anisamid-derivater samt 2-methoxy-4-amino-5-alkylsulfonylbenzoesyrer til anvendelse som mellemprodukter ved fremgangsmaaden DK158346C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7801632A FR2415099A1 (fr) 1978-01-20 1978-01-20 Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes
FR7801632 1978-01-20

Publications (3)

Publication Number Publication Date
DK20979A DK20979A (da) 1979-07-21
DK158346B DK158346B (da) 1990-05-07
DK158346C true DK158346C (da) 1990-10-08

Family

ID=9203689

Family Applications (1)

Application Number Title Priority Date Filing Date
DK020979A DK158346C (da) 1978-01-20 1979-01-18 Analogifremgangsmaade til fremstilling af 4-amino-5-alkylsulfonyl-o-anisamid-derivater samt 2-methoxy-4-amino-5-alkylsulfonylbenzoesyrer til anvendelse som mellemprodukter ved fremgangsmaaden

Country Status (42)

Country Link
US (2) US4294828A (nl)
JP (1) JPS6049192B2 (nl)
AR (2) AR221354A1 (nl)
AT (1) AT377977B (nl)
AU (1) AU528561B2 (nl)
BE (1) BE872585A (nl)
BG (2) BG31496A3 (nl)
CA (1) CA1101430A (nl)
CH (1) CH637927A5 (nl)
CS (1) CS226181B2 (nl)
CY (1) CY1201A (nl)
DD (1) DD141520A5 (nl)
DE (1) DE2901181C2 (nl)
DK (1) DK158346C (nl)
EG (1) EG14045A (nl)
ES (2) ES476755A1 (nl)
FI (1) FI71126C (nl)
FR (1) FR2415099A1 (nl)
GB (2) GB2083458B (nl)
GR (1) GR64431B (nl)
HK (1) HK12184A (nl)
HU (1) HU179793B (nl)
IE (1) IE47798B1 (nl)
IL (1) IL56411A (nl)
IN (1) IN150226B (nl)
IT (1) IT1164655B (nl)
LU (1) LU80786A1 (nl)
MC (1) MC1232A1 (nl)
MX (2) MX5793E (nl)
NL (1) NL191707C (nl)
NO (1) NO151320C (nl)
NZ (1) NZ189378A (nl)
OA (1) OA06156A (nl)
PH (2) PH15725A (nl)
PL (2) PL116532B1 (nl)
PT (1) PT69068A (nl)
RO (2) RO76393A (nl)
SE (2) SE448874B (nl)
SU (1) SU820659A3 (nl)
YU (2) YU42172B (nl)
ZA (1) ZA79219B (nl)
ZM (1) ZM579A1 (nl)

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FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
ZA818221B (en) * 1980-12-12 1982-10-27 Beecham Group Plc Pharmaceutical compounds
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
FR2584401B1 (fr) * 1985-07-04 1987-11-20 Ile De France Nouveau benzamide, son procede de preparation et son application dans le domaine therapeutique
US5227388A (en) * 1989-12-26 1993-07-13 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
FR2678266A1 (fr) * 1991-06-28 1992-12-31 Delagrange Laboratoires Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques.
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
FR2753376B1 (fr) * 1996-09-18 1998-10-16 Synthelabo Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques
FR2762213B1 (fr) * 1997-04-18 1999-05-14 Synthelabo Composition pharmaceutique a retention gastrique
US6169094B1 (en) * 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
RU2005135454A (ru) * 2003-05-16 2006-06-27 Пфайзер Продактс Инк. (Us) Терапевтические комбинации атипичных нейролептиков с модуляторами гамк и/или противосудорожными препаратами
FR2857263B1 (fr) * 2003-07-09 2005-09-09 Sanofi Synthelabo Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
MXPA06013163A (es) * 2004-05-11 2007-02-13 Pfizer Prod Inc Combinacion de antipsicoticos atipicos y antagonistas del receptor 5-ht1b.
AU2006239900A1 (en) * 2005-04-22 2006-11-02 Wyeth Therapeutic combinations for the treatment or prevention of psychotic disorders
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
US7825156B2 (en) * 2007-02-02 2010-11-02 Copharms Method of treating bipolar depression with a benzamide derivative
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
WO2009156889A1 (en) * 2008-06-25 2009-12-30 Pfizer Inc. Diaryl compounds and uses thereof
US20100105755A1 (en) * 2008-09-12 2010-04-29 Auspex Pharmaceuticals, Inc. Substituted benzamide modulators of dopamine receptor
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
EP2427178B1 (en) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
CN101898991B (zh) * 2009-05-31 2013-09-25 江苏天士力帝益药业有限公司 一种(s)(-)-氨磺必利d-(-)-酒石酸盐的合成方法
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法
AU2016216578B2 (en) * 2010-03-11 2017-11-23 Acacia Pharma Limited The use of amisulpride as an anti-emetic
GB201004020D0 (en) 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
AU2014202535B2 (en) * 2010-03-11 2016-05-26 Acacia Pharma Limited The use of amisulpride as an anti-emetic
EP2582665A1 (en) 2010-06-17 2013-04-24 Lupin Limited An improved process for preparation of amisulpride
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103304453A (zh) * 2013-06-18 2013-09-18 苏州诚和医药化学有限公司 两步法合成2-甲氧基-4-氨基-5-乙砜基苯甲酸
CN103319384A (zh) * 2013-06-18 2013-09-25 苏州诚和医药化学有限公司 制备2-甲氧基-4-氨基-5-乙砜基苯甲酸的方法
CN103450058B (zh) * 2013-09-18 2015-10-14 广安凯特医药化工有限公司 一种氨磺必利酸的制备方法
CN104725292B (zh) * 2015-03-23 2017-07-25 湖北荆江源制药股份有限公司 一种(s)(‑)‑氨磺必利的制备方法
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
BR112019010127A2 (pt) * 2016-11-28 2019-08-20 Lb Pharmaceuticals Inc agentes psicotrópicos e usos dos mesmos
US11377421B2 (en) 2016-11-28 2022-07-05 Lb Pharmaceuticals Inc. Psychotropic agents and uses thereof
CN106995397B (zh) * 2016-12-12 2020-01-14 河北医科大学 R-氨磺必利药用盐、制备方法、晶型及其用途
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
JP2021505595A (ja) 2017-12-05 2021-02-18 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 結晶形およびその製造方法
WO2019113079A1 (en) 2017-12-05 2019-06-13 Sunovion Pharmaceuticals Inc. Nonracemic mixtures and uses thereof
CN110790693A (zh) * 2018-08-02 2020-02-14 北京万全德众医药生物技术有限公司 一种(s)(-)-氨磺必利的制备方法
SG11202113266YA (en) 2019-06-04 2021-12-30 Sunovion Pharmaceuticals Inc Modified release formulations and uses thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR2313935A1 (fr) * 1975-06-10 1977-01-07 Ile De France Nouveaux benzamides substitues, leurs derives et leur procede de preparation
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (nl) * 1973-09-25 1980-06-27 Ile De France
FR2299862B1 (fr) * 1975-02-07 1978-07-21 Ile De France Nouveau
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
SE412908B (sv) * 1974-12-18 1980-03-24 Synthelabo Forfarande for framstellning av terapeutiskt aktiva 2-metoxibensamider innehallande en pyrrolidin- eller en piperidinrest

Also Published As

Publication number Publication date
IE47798B1 (en) 1984-06-27
IT7947706A0 (it) 1979-01-18
PL118151B1 (en) 1981-09-30
NO790180L (no) 1979-07-23
IL56411A0 (en) 1979-03-12
PT69068A (fr) 1979-02-01
LU80786A1 (fr) 1979-09-07
GB2083458B (en) 1983-03-09
FI71126B (fi) 1986-08-14
NL7900457A (nl) 1979-07-24
GR64431B (en) 1980-03-21
AU4337379A (en) 1979-07-26
GB2083458A (en) 1982-03-24
MC1232A1 (fr) 1979-10-26
IE790092L (en) 1979-07-20
DD141520A5 (de) 1980-05-07
FI71126C (fi) 1986-11-24
SE8603773L (sv) 1986-09-09
FR2415099B1 (nl) 1981-02-20
NZ189378A (en) 1983-03-15
PL212899A1 (nl) 1980-01-14
IT1164655B (it) 1987-04-15
CH637927A5 (fr) 1983-08-31
AR221354A1 (es) 1981-01-30
FI790182A (fi) 1979-07-21
YU25483A (en) 1983-10-31
YU5079A (en) 1983-06-30
DE2901181C2 (de) 1984-07-19
DE2901181A1 (de) 1979-07-26
PL116532B1 (en) 1981-06-30
BE872585A (fr) 1979-06-07
AR220574A1 (es) 1980-11-14
SE448874B (sv) 1987-03-23
RO76393A (ro) 1981-03-30
CY1201A (en) 1983-12-31
YU41278B (en) 1986-12-31
HK12184A (en) 1984-02-24
SE7900380L (sv) 1979-07-21
GB2012765A (en) 1979-08-01
DK158346B (da) 1990-05-07
BG31496A3 (en) 1982-01-15
ZM579A1 (en) 1979-12-21
PH22287A (en) 1988-07-22
AT377977B (de) 1985-05-28
IN150226B (nl) 1982-08-21
NL191707B (nl) 1995-12-01
CS226181B2 (en) 1984-03-19
US4294828A (en) 1981-10-13
YU42172B (en) 1988-06-30
NL191707C (nl) 1996-04-02
CA1101430A (en) 1981-05-19
MX7623E (es) 1990-03-27
SU820659A3 (ru) 1981-04-07
US4401822A (en) 1983-08-30
OA06156A (fr) 1981-06-30
SE8603773D0 (sv) 1986-09-09
NO151320C (no) 1985-04-17
BG31497A3 (en) 1982-01-15
FR2415099A1 (fr) 1979-08-17
JPS6049192B2 (ja) 1985-10-31
EG14045A (en) 1983-09-30
JPS54145658A (en) 1979-11-14
RO80311A (ro) 1982-12-06
IL56411A (en) 1982-09-30
NO151320B (no) 1984-12-10
MX5793E (es) 1984-07-19
PH15725A (en) 1983-03-18
AU528561B2 (en) 1983-05-05
ES477782A1 (es) 1979-09-16
ES476755A1 (es) 1979-06-01
HU179793B (en) 1982-12-28
ZA79219B (en) 1980-01-30
SE460968B (sv) 1989-12-11
DK20979A (da) 1979-07-21
GB2012765B (en) 1982-09-08
ATA39879A (de) 1983-12-15

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