DK157931C - 1,3-dihydro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridinderivater og terapeutisk acceptable syreadditionssalte deraf samt farmaceutiske praeparater indeholdende disse - Google Patents

1,3-dihydro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridinderivater og terapeutisk acceptable syreadditionssalte deraf samt farmaceutiske praeparater indeholdende disse

Info

Publication number
DK157931C
DK157931C DK178084A DK178084A DK157931C DK 157931 C DK157931 C DK 157931C DK 178084 A DK178084 A DK 178084A DK 178084 A DK178084 A DK 178084A DK 157931 C DK157931 C DK 157931C
Authority
DK
Denmark
Prior art keywords
furo
dihydro
hydroxy
methyl
acid addition
Prior art date
Application number
DK178084A
Other languages
Danish (da)
English (en)
Other versions
DK178084A (da
DK157931B (da
DK178084D0 (da
Inventor
Andre Esanu
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838327815A external-priority patent/GB8327815D0/en
Application filed by Scras filed Critical Scras
Publication of DK178084D0 publication Critical patent/DK178084D0/da
Publication of DK178084A publication Critical patent/DK178084A/da
Publication of DK157931B publication Critical patent/DK157931B/da
Application granted granted Critical
Publication of DK157931C publication Critical patent/DK157931C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
DK178084A 1983-04-05 1984-04-04 1,3-dihydro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridinderivater og terapeutisk acceptable syreadditionssalte deraf samt farmaceutiske praeparater indeholdende disse DK157931C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8309165 1983-04-05
GB8309165 1983-04-05
GB8327815 1983-10-18
GB838327815A GB8327815D0 (en) 1983-10-18 1983-10-18 Furo-(3 4-c)-pyridine derivatives

Publications (4)

Publication Number Publication Date
DK178084D0 DK178084D0 (da) 1984-04-04
DK178084A DK178084A (da) 1984-10-06
DK157931B DK157931B (da) 1990-03-05
DK157931C true DK157931C (da) 1990-08-27

Family

ID=26285725

Family Applications (1)

Application Number Title Priority Date Filing Date
DK178084A DK157931C (da) 1983-04-05 1984-04-04 1,3-dihydro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridinderivater og terapeutisk acceptable syreadditionssalte deraf samt farmaceutiske praeparater indeholdende disse

Country Status (29)

Country Link
US (1) US4581363A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS59193888A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR900005518B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU582113B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1257269A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH660191A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3412885C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK157931C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DZ (1) DZ629A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EG (1) EG18150A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8601998A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI76804C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (2) FR2543956B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR79577B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK11187A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE57424B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL71243A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN160104B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1173770B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU85262A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MA (1) MA20084A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX167397B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY8600664A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL190328C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO161802C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ207552A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA07699A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT78361B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE458362B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735950A (en) * 1983-04-05 1988-04-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
DE3990349T1 (de) * 1988-04-06 1990-04-26 Scras Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
DK1169322T3 (da) 1999-03-08 2006-03-06 Medicure Inc Pyridoxalanaloger til behandling af lidelser foranlediget af vitamin B6-mangel
AU5840200A (en) 1999-07-13 2001-01-30 Medicure Inc. Treatment of diabetes and related pathologies
EP1210117A2 (en) * 1999-08-24 2002-06-05 Medicure International Inc. Compositons for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
ATE293119T1 (de) 2000-02-29 2005-04-15 Medicure Int Inc Cardioprotektive phosphonate
JP2003528146A (ja) 2000-03-28 2003-09-24 メディキュア インターナショナル インコーポレイテッド 脳血管疾患の治療
NZ523815A (en) 2000-07-07 2004-07-30 Medicure Int Inc Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
US6897228B2 (en) * 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US20040121988A1 (en) * 2001-03-28 2004-06-24 Medicure International Inc. Treatment of cerebrovascular disease
US20040186077A1 (en) * 2003-03-17 2004-09-23 Medicure International Inc. Novel heteroaryl phosphonates as cardioprotective agents
CA2570048A1 (en) * 2004-07-07 2006-01-12 Medicure International Inc. Combination therapies employing platelet aggregation drugs
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
US7459468B2 (en) * 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
JP2008517956A (ja) * 2004-10-28 2008-05-29 メディキュア・インターナショナル・インコーポレーテッド 二重の抗血小板性／抗凝固性ピリドキシン類似体
US20060094749A1 (en) * 2004-10-28 2006-05-04 Medicure International Inc. Substituted pyridoxines as anti-platelet agents
WO2007059631A1 (en) * 2005-11-28 2007-05-31 Medicure International Inc. Selected dosage for the treatment of cardiovascular and related pathologies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use
GB2008582B (en) * 1977-11-25 1982-04-28 Scras Pyridine derivative
IN156817B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1981-02-10 1985-11-09 Scras

Also Published As

Publication number Publication date
CA1257269A (en) 1989-07-11
KR840008651A (ko) 1984-12-17
DK178084A (da) 1984-10-06
HK11187A (en) 1987-02-13
NL190328C (nl) 1994-01-17
DZ629A1 (fr) 2004-09-13
IL71243A (en) 1987-12-20
IT8420396A0 (it) 1984-04-05
FI841273A0 (fi) 1984-03-30
MX167397B (es) 1993-03-22
IL71243A0 (en) 1984-06-29
SE8401841L (sv) 1984-10-06
IT1173770B (it) 1987-06-24
PT78361B (en) 1986-05-28
SE458362B (sv) 1989-03-20
CH660191A5 (fr) 1987-03-31
JPH0556353B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-08-19
DK157931B (da) 1990-03-05
FR2543829A1 (fr) 1984-10-12
FI841273L (fi) 1984-10-06
IE840826L (en) 1984-10-05
NZ207552A (en) 1986-05-09
FR2543956B1 (fr) 1986-07-04
EG18150A (en) 1992-08-30
SE8401841D0 (sv) 1984-04-03
US4581363A (en) 1986-04-08
DE3412885A1 (de) 1984-10-11
MY8600664A (en) 1986-12-31
JPS59193888A (ja) 1984-11-02
PT78361A (en) 1984-05-01
NO161802C (no) 1989-09-27
NO161802B (no) 1989-06-19
FI76804B (fi) 1988-08-31
MA20084A1 (fr) 1984-12-31
FR2543956A1 (fr) 1984-10-12
NL190328B (nl) 1993-08-16
GR79577B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-10-30
KR900005518B1 (ko) 1990-07-30
AU2640184A (en) 1984-10-11
ES531285A0 (es) 1985-11-01
ES8601998A1 (es) 1985-11-01
FI76804C (fi) 1988-12-12
DK178084D0 (da) 1984-04-04
NO841322L (no) 1984-10-08
OA07699A (fr) 1985-08-30
FR2543829B1 (fr) 1986-11-21
DE3412885C2 (de) 1990-10-04
IE57424B1 (en) 1992-09-09
NL8401013A (nl) 1984-11-01
LU85262A1 (fr) 1984-10-24
IN160104B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-06-27
AU582113B2 (en) 1989-03-16

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