DK157543C - Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelse - Google Patents
Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelseInfo
- Publication number
- DK157543C DK157543C DK083886A DK83886A DK157543C DK 157543 C DK157543 C DK 157543C DK 083886 A DK083886 A DK 083886A DK 83886 A DK83886 A DK 83886A DK 157543 C DK157543 C DK 157543C
- Authority
- DK
- Denmark
- Prior art keywords
- 3alkyl
- phenoxy
- fluoro
- chloro
- trifluoromethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/382—Information transfer, e.g. on bus using universal interface adapter
- G06F13/387—Information transfer, e.g. on bus using universal interface adapter for adaptation of different data processing systems to different peripheral devices, e.g. protocol converters for incompatible systems, open system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/40—Bus structure
- G06F13/4004—Coupling between buses
- G06F13/4009—Coupling between buses with data restructuring
- G06F13/4018—Coupling between buses with data restructuring with data-width conversion
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62339384A | 1984-06-22 | 1984-06-22 | |
US62339384 | 1984-06-22 | ||
PCT/EP1985/000293 WO1986000307A2 (fr) | 1984-06-22 | 1985-06-18 | Analogues pyrazole de la mevalonolactone et leurs derives, leurs procedes de preparation et leur utilisation |
EP8500293 | 1985-06-18 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK83886D0 DK83886D0 (da) | 1986-02-21 |
DK83886A DK83886A (da) | 1986-02-21 |
DK157543B DK157543B (da) | 1990-01-22 |
DK157543C true DK157543C (da) | 1990-06-11 |
Family
ID=24497918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK083886A DK157543C (da) | 1984-06-22 | 1986-02-21 | Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelse |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0200736B1 (fr) |
JP (1) | JPS61502467A (fr) |
KR (1) | KR890001651B1 (fr) |
AT (1) | ATE62906T1 (fr) |
AU (1) | AU573368B2 (fr) |
CA (1) | CA1249283A (fr) |
DE (1) | DE3582674D1 (fr) |
DK (1) | DK157543C (fr) |
ES (1) | ES8703842A1 (fr) |
FI (1) | FI860755A (fr) |
GR (1) | GR851510B (fr) |
HU (1) | HU198711B (fr) |
IL (1) | IL75583A (fr) |
MY (1) | MY101903A (fr) |
NZ (1) | NZ212501A (fr) |
PL (1) | PL151016B1 (fr) |
PT (1) | PT80674B (fr) |
WO (1) | WO1986000307A2 (fr) |
ZA (1) | ZA854719B (fr) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
WO1987002662A2 (fr) * | 1985-10-25 | 1987-05-07 | Sandoz Ag | Analogues heterocycliques de mevalonolactone et leurs derives, procedes de production et utilisation en tant que produits pharmaceutiques |
JPS6322056A (ja) * | 1986-04-30 | 1988-01-29 | サンド・アクチエンゲゼルシヤフト | オレフイン性化合物の製造法 |
US4808621A (en) * | 1986-07-07 | 1989-02-28 | Warner-Lambert Company | Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
NZ221717A (en) * | 1986-09-10 | 1990-08-28 | Sandoz Ltd | Azaindole and indolizine derivatives and pharmaceutical compositions |
US4751235A (en) * | 1986-12-23 | 1988-06-14 | Sandoz Pharm. Corp. | Anti-atherosclerotic indolizine derivatives |
US4735958A (en) * | 1986-12-22 | 1988-04-05 | Warner-Lambert Company | Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis |
US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
US4898949A (en) * | 1987-02-25 | 1990-02-06 | Bristol-Myers Company | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
AT401518B (de) * | 1987-02-25 | 1996-09-25 | Bristol Myers Squibb Co | Neue tetrazol-verbindungen und verfahren zu ihrer herstellung |
CA1336714C (fr) * | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Mevalonolactone de type quinoleine utilisee comme inhibiteurs de la biosynthese du cholesterol |
JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
US4997837A (en) * | 1987-09-08 | 1991-03-05 | Warner-Lambert Company | 6-(((substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
US4906624A (en) * | 1987-09-08 | 1990-03-06 | Warner-Lambert Company | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
US4822799A (en) * | 1988-01-27 | 1989-04-18 | Sandoz Pharm. Corp. | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals |
NO890522L (no) * | 1988-02-25 | 1989-08-28 | Bayer Ag | Substituerte imidazolinoner og imidazolinthioner. |
JP2890448B2 (ja) * | 1988-04-26 | 1999-05-17 | 日産化学工業株式会社 | ピラゾロピリジン系メバロノラクトン類 |
US5024999A (en) * | 1988-04-26 | 1991-06-18 | Nissan Chemical Industries Ltd. | Pyrazolopyridine type mevalonolactones useful as pharmaeuticals |
IL91941A (en) * | 1988-10-13 | 1994-10-21 | Sandoz Ag | Preparation of 6-Anoic and 7-Metanoic Fatty Acids and Their Substances and Intermediate Compounds and Acid 7-] 3-) 4-Fluorophenyl (-1-) 1- Methylethyl (a) |
JPH04270285A (ja) * | 1988-11-14 | 1992-09-25 | Nissan Chem Ind Ltd | ピラゾロピリミジン系メバロノラクトン類 |
IT1237793B (it) * | 1989-12-21 | 1993-06-17 | Zambon Spa | Composti attivi come inibitori dell'enzima hmg-coa reduttasi |
US5134155A (en) * | 1991-08-08 | 1992-07-28 | Ortho Pharmaceutical Corporation | Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors |
JPH07507200A (ja) * | 1991-09-20 | 1995-08-10 | ゼネカ リミテッド | ピラノン |
US5335293A (en) * | 1992-06-16 | 1994-08-02 | Key Technology, Inc. | Product inspection method and apparatus |
ZA200503967B (en) | 2002-11-01 | 2006-11-29 | Takeda Pharmaceutical | Agent for preventing or treating neuropathy |
EP1819681B1 (fr) | 2004-11-23 | 2009-08-12 | Warner-Lambert Company LLC | Derives d'acide 7-(2h-pyrazol-3-yl)-3, 5-dihyroxy-heptanoique comme inhibiteurs de hmg co-a reductase pour le traitement de l'hyperlipidemie |
WO2006087630A2 (fr) * | 2005-02-16 | 2006-08-24 | Warner-Lambert Company Llc | Inhibiteurs oxypyrazole de l'enzyme hmg co-a reductase |
EP1775299A1 (fr) * | 2005-10-05 | 2007-04-18 | LEK Pharmaceuticals D.D. | Procédé de préparation de inhibiteurs de la HMG-CoA réductase |
TW200736225A (en) * | 2006-01-16 | 2007-10-01 | Sankyo Agro Co Ltd | A (3-sulfur substituted phenyl) pyrazole derivative |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1261124B (de) * | 1961-09-22 | 1968-02-15 | Hoechst Ag | Verfahren zur Herstellung von Pyrazolen |
DE2920933A1 (de) * | 1979-05-23 | 1980-12-04 | Basf Ag | 3-aryl-5-methyl-pyrazol-4-carbonsaeureester enthaltende herbizide |
US4245106A (en) * | 1979-07-05 | 1981-01-13 | Monsanto Company | Process for the preparation of 1-alkyl-3-aryl-4-pyrazolecarboxylates |
-
1985
- 1985-06-18 AU AU45466/85A patent/AU573368B2/en not_active Ceased
- 1985-06-18 EP EP85903248A patent/EP0200736B1/fr not_active Expired - Lifetime
- 1985-06-18 AT AT85903248T patent/ATE62906T1/de not_active IP Right Cessation
- 1985-06-18 WO PCT/EP1985/000293 patent/WO1986000307A2/fr active IP Right Grant
- 1985-06-18 KR KR1019860700100A patent/KR890001651B1/ko not_active IP Right Cessation
- 1985-06-18 JP JP60502997A patent/JPS61502467A/ja active Pending
- 1985-06-18 DE DE8585903248T patent/DE3582674D1/de not_active Expired - Lifetime
- 1985-06-18 HU HU853053A patent/HU198711B/hu not_active IP Right Cessation
- 1985-06-20 PT PT80674A patent/PT80674B/pt not_active IP Right Cessation
- 1985-06-20 GR GR851510A patent/GR851510B/el unknown
- 1985-06-20 IL IL75583A patent/IL75583A/xx unknown
- 1985-06-20 NZ NZ212501A patent/NZ212501A/xx unknown
- 1985-06-21 PL PL1985254121A patent/PL151016B1/pl unknown
- 1985-06-21 ZA ZA854719A patent/ZA854719B/xx unknown
- 1985-06-21 CA CA000484847A patent/CA1249283A/fr not_active Expired
- 1985-06-21 ES ES544407A patent/ES8703842A1/es not_active Expired
-
1986
- 1986-02-20 FI FI860755A patent/FI860755A/fi not_active Application Discontinuation
- 1986-02-21 DK DK083886A patent/DK157543C/da not_active IP Right Cessation
-
1987
- 1987-09-26 MY MYPI87001978A patent/MY101903A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FI860755A0 (fi) | 1986-02-20 |
DK157543B (da) | 1990-01-22 |
HUT39178A (en) | 1986-08-28 |
FI860755A (fi) | 1986-02-20 |
DE3582674D1 (de) | 1991-05-29 |
KR860700253A (ko) | 1986-08-01 |
ES8703842A1 (es) | 1987-03-01 |
IL75583A0 (en) | 1985-10-31 |
NZ212501A (en) | 1988-06-30 |
JPS61502467A (ja) | 1986-10-30 |
ZA854719B (en) | 1987-02-25 |
PT80674A (en) | 1985-07-01 |
PL254121A1 (en) | 1988-07-21 |
EP0200736B1 (fr) | 1991-04-24 |
KR890001651B1 (ko) | 1989-05-12 |
WO1986000307A2 (fr) | 1986-01-16 |
IL75583A (en) | 1989-09-10 |
AU573368B2 (en) | 1988-06-02 |
ATE62906T1 (de) | 1991-05-15 |
EP0200736A1 (fr) | 1986-11-12 |
GR851510B (fr) | 1985-11-25 |
AU4546685A (en) | 1986-01-24 |
DK83886D0 (da) | 1986-02-21 |
MY101903A (en) | 1992-02-15 |
PT80674B (en) | 1987-03-17 |
HU198711B (en) | 1989-11-28 |
DK83886A (da) | 1986-02-21 |
CA1249283A (fr) | 1989-01-24 |
WO1986000307A3 (fr) | 1986-04-10 |
PL151016B1 (en) | 1990-07-31 |
ES544407A0 (es) | 1987-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |