DK155792C - Analogifremgangsmaade til fremstilling af pyrrol-eddikesyreamider eller salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af pyrrol-eddikesyreamider eller salte deraf

Info

Publication number
DK155792C
DK155792C DK070083A DK70083A DK155792C DK 155792 C DK155792 C DK 155792C DK 070083 A DK070083 A DK 070083A DK 70083 A DK70083 A DK 70083A DK 155792 C DK155792 C DK 155792C
Authority
DK
Denmark
Prior art keywords
amoids
pyrrol
analogy
salts
preparation
Prior art date
Application number
DK070083A
Other languages
Danish (da)
English (en)
Other versions
DK155792B (da
DK70083D0 (da
DK70083A (da
Inventor
Alessandro Baglioni
Original Assignee
Sigma Tau Ind Farmaceuti
Medosan Ind Biochimi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti, Medosan Ind Biochimi filed Critical Sigma Tau Ind Farmaceuti
Publication of DK70083D0 publication Critical patent/DK70083D0/da
Publication of DK70083A publication Critical patent/DK70083A/da
Publication of DK155792B publication Critical patent/DK155792B/da
Application granted granted Critical
Publication of DK155792C publication Critical patent/DK155792C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK070083A 1982-02-26 1983-02-17 Analogifremgangsmaade til fremstilling af pyrrol-eddikesyreamider eller salte deraf DK155792C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT4788182 1982-02-26
IT8247881A IT1210673B (it) 1982-02-26 1982-02-26 Antinfiammatoria amidi pirrolacetiche ad attivita'

Publications (4)

Publication Number Publication Date
DK70083D0 DK70083D0 (da) 1983-02-17
DK70083A DK70083A (da) 1983-08-27
DK155792B DK155792B (da) 1989-05-16
DK155792C true DK155792C (da) 1989-10-09

Family

ID=11263094

Family Applications (1)

Application Number Title Priority Date Filing Date
DK070083A DK155792C (da) 1982-02-26 1983-02-17 Analogifremgangsmaade til fremstilling af pyrrol-eddikesyreamider eller salte deraf

Country Status (22)

Country Link
US (2) US4882349A (de)
JP (2) JPS58159458A (de)
KR (1) KR890004127B1 (de)
AT (1) AT376204B (de)
BE (1) BE896018A (de)
CA (1) CA1207769A (de)
CH (1) CH658650A5 (de)
DE (1) DE3306006A1 (de)
DK (1) DK155792C (de)
ES (1) ES520112A0 (de)
FI (1) FI77227C (de)
FR (1) FR2522324B1 (de)
GB (1) GB2115417B (de)
GR (1) GR77920B (de)
IE (1) IE54896B1 (de)
IL (1) IL67929A (de)
IT (1) IT1210673B (de)
LU (1) LU84660A1 (de)
MX (1) MX161088A (de)
NL (1) NL193217C (de)
SE (1) SE453388B (de)
ZA (1) ZA831110B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1210673B (it) * 1982-02-26 1989-09-20 Medosan Ind Biochimi Antinfiammatoria amidi pirrolacetiche ad attivita'
YU251283A (en) * 1983-01-26 1986-04-30 Mcneilab Inc Process for obtaining pyrrol-2-acetylamino acid derivatives
US4585784A (en) * 1983-01-26 1986-04-29 Mcneilab, Inc. Pyrrole-2-acetylamino acid derivative compounds
IT1197688B (it) * 1983-07-29 1988-12-06 Medosan Ind Biochimi Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi
US6180658B1 (en) 1995-07-14 2001-01-30 Medosan Ricerca S.R.L. Method for counteracting blood platelet aggregation in a patient in need thereof
US5889041A (en) * 1995-07-14 1999-03-30 Medosan Ricerca S.R.L. Method for treating an inflammatory pathological condition
IT1278144B1 (it) * 1995-07-14 1997-11-17 Medosan Ricerca Srl Impiego dell'amtolmetineguacil (med 15) come farmaco antisecretivo sulla secrezione gastrica e quindi gastroprotettivo.
WO1999007363A1 (en) * 1997-08-08 1999-02-18 Medosan, Ricerca S.R.L. Use of the compound 2-methoxyphenyl-1-methyl-5p-methylbenzoyl-pyrrol-2-acetamido acetate for the production of an anti-inflammatory drug with prevention of gastric hypersecretion and renal impairment
IT1297140B1 (it) * 1997-12-24 1999-08-03 Sigma Tau Ind Farmaceuti Forma cristallina del guaiacil estere dell'acido l-metil-5-p-toluoil- pirrol-2-acetammidoacetico, procedimento per la sua preparazione e
IT1302898B1 (it) 1998-12-03 2000-10-10 Medosan Ricerca Srl Uso di amtolmetine guacil per la produzione di farmaci ad effettoantiinfiammatorio nelle infiammazioni intestinali.
EP1328225B1 (de) 2000-09-15 2010-03-10 Bruder Healthcare Company Wund- und behandlungskompresse und verband
US9925087B2 (en) 2000-09-15 2018-03-27 Bruder Healthcare Company, Llc Wound and therapy compress and dressing
US10105259B2 (en) 2000-09-15 2018-10-23 Bruder Healthcare Company, Llc Wound and therapy compress and dressing
CN100390144C (zh) * 2006-03-29 2008-05-28 安徽省庆云医药化工有限公司 1-甲基-5-对甲苯酰吡咯-2-乙酰氨基乙酸愈创木酚酯的制备方法
WO2014143139A1 (en) 2013-03-15 2014-09-18 Bruder Healthcare Company Wound and therapy compress and dressing
US12029681B2 (en) 2016-03-01 2024-07-09 The Hilsinger Company Parent, Llc Therapeutic eye mask system
US12011388B2 (en) 2016-03-01 2024-06-18 The Hilsinger Company Parent, Llc Therapeutic thermal compress with phase-change material
USD844795S1 (en) 2016-11-30 2019-04-02 Bruder Healthcare Company, Llc Therapeutic eye mask
USD871598S1 (en) 2016-11-30 2019-12-31 Bruder Healthcare Company, Llc Therapeutic eye mask

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE338993B (de) * 1967-07-26 1971-09-27 Mcneilab Inc
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
US3952012A (en) * 1970-01-26 1976-04-20 Mcneil Laboratories, Incorporated Aroyl-substituted pyrroles
US3950012A (en) * 1975-03-17 1976-04-13 Donovan Robert G Retainer for multi-leafed devices
US4200645A (en) * 1977-05-10 1980-04-29 Beecham Group Limited Pyrrole derivatives
JPS5524141A (en) * 1978-08-11 1980-02-21 Sagami Chem Res Center 1-alkyl-5-(p-toluoyl)-pyrrolyl-2thioacetamide derivative
US4396626A (en) * 1980-10-09 1983-08-02 Beecham Group Limited Cyclic compounds and their use
ES497136A0 (es) * 1980-11-11 1981-10-16 Calzada & Co Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico
JPS57144256A (en) * 1981-03-03 1982-09-06 Sagami Chem Res Center Preparation of (1-alkyl-5-toluoyl-2-pyrrolyl)acetamide derivative
IT1137229B (it) * 1981-05-26 1986-09-03 Poli Ind Chimica Spa Composto solubile ad attivita' analgesica
US4434175A (en) * 1981-08-10 1984-02-28 Merck & Co., Inc. Nonsteroidal compounds as anti-inflammatory and analgesic agents
IT1210673B (it) * 1982-02-26 1989-09-20 Medosan Ind Biochimi Antinfiammatoria amidi pirrolacetiche ad attivita'
IT1148117B (it) * 1982-03-05 1986-11-26 Medosan Ind Biochimi Attivita'antiflogistica,analgesica,antipiretica,mucolitica e seda tiva della tosse dell'1 metil-5-p-tolilpirrol-2-acetato di 2'metossi-fenile
YU251283A (en) * 1983-01-26 1986-04-30 Mcneilab Inc Process for obtaining pyrrol-2-acetylamino acid derivatives
IT1174773B (it) * 1983-07-29 1987-07-01 Medosan Ind Biochimi Attivita' antiaggregante piastrinica e broncolitica della 7-(1-metil-5-p-metilbenzoilpirrol-2-acetamidoetil)teofillina
IT1197688B (it) * 1983-07-29 1988-12-06 Medosan Ind Biochimi Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi

Also Published As

Publication number Publication date
FI830556A0 (fi) 1983-02-18
ES8403453A1 (es) 1984-04-01
ES520112A0 (es) 1984-04-01
FI830556L (fi) 1983-08-27
IL67929A (en) 1986-10-31
FI77227B (fi) 1988-10-31
NL193217B (nl) 1998-11-02
FR2522324A1 (fr) 1983-09-02
DE3306006C2 (de) 1992-02-06
CA1207769A (en) 1986-07-15
KR840003614A (ko) 1984-09-15
DE3306006A1 (de) 1983-09-08
NL8300693A (nl) 1983-09-16
JPH0662562B2 (ja) 1994-08-17
DK155792B (da) 1989-05-16
GB2115417B (en) 1985-07-31
AT376204B (de) 1984-10-25
IE830310L (en) 1983-08-26
MX161088A (es) 1990-07-25
SE8301008D0 (sv) 1983-02-23
ATA67383A (de) 1984-03-15
JPH04210963A (ja) 1992-08-03
DK70083D0 (da) 1983-02-17
DK70083A (da) 1983-08-27
GB2115417A (en) 1983-09-07
FI77227C (fi) 1989-02-10
JPH0350728B2 (de) 1991-08-02
IE54896B1 (en) 1990-03-14
SE453388B (sv) 1988-02-01
IT8247881A0 (it) 1982-02-26
GB8304996D0 (en) 1983-03-30
GR77920B (de) 1984-09-25
US4882349A (en) 1989-11-21
LU84660A1 (fr) 1983-09-08
ZA831110B (en) 1984-03-28
BE896018A (fr) 1983-06-16
JPS58159458A (ja) 1983-09-21
SE8301008L (sv) 1983-08-27
IT1210673B (it) 1989-09-20
KR890004127B1 (ko) 1989-10-21
US4578481A (en) 1986-03-25
NL193217C (nl) 1999-03-03
CH658650A5 (it) 1986-11-28
IL67929A0 (en) 1983-06-15
FR2522324B1 (fr) 1985-07-19

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Legal Events

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PUP Patent expired