ES497136A0 - Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico - Google Patents
Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-ticoInfo
- Publication number
- ES497136A0 ES497136A0 ES497136A ES497136A ES497136A0 ES 497136 A0 ES497136 A0 ES 497136A0 ES 497136 A ES497136 A ES 497136A ES 497136 A ES497136 A ES 497136A ES 497136 A0 ES497136 A0 ES 497136A0
- Authority
- ES
- Spain
- Prior art keywords
- acetamide
- hydroxyphenyl
- esters
- synthesis
- methylpyrol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- RZVAJINKPMORJF-UHFFFAOYSA-N N-acetyl-para-amino-phenol Natural products CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
- WVKPVCGHCFYVKZ-UHFFFAOYSA-N 2-(5-benzoyl-1-methylpyrrol-2-yl)acetic acid Chemical class CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=CC=C1 WVKPVCGHCFYVKZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES497136A ES8200092A1 (es) | 1980-11-11 | 1980-11-11 | Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico |
| US06/285,341 US4379793A (en) | 1980-11-11 | 1981-07-20 | Process for synthesis of esters of N-(4'-hydroxyphenyl)acetamide with derivatives of 5-benzoil-1-methyl pyrrole-2-acetic acids |
| EP81305251A EP0051981B1 (en) | 1980-11-11 | 1981-11-04 | Esters of n-(4'-hydroxyphenyl)acetamide with 5-benzoyl-1-methylpyrrole-2-acetic acids |
| AT81305251T ATE18208T1 (de) | 1980-11-11 | 1981-11-04 | N-(4-hydroxyphenyl)essigsaeureamid-estern aus 5benzoyl-1-methylpyrrol-2-essigsaeure. |
| DE8181305251T DE3173904D1 (en) | 1980-11-11 | 1981-11-04 | Esters of n-(4'-hydroxyphenyl)acetamide with 5-benzoyl-1-methylpyrrole-2-acetic acids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES497136A ES8200092A1 (es) | 1980-11-11 | 1980-11-11 | Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES497136A0 true ES497136A0 (es) | 1981-10-16 |
| ES8200092A1 ES8200092A1 (es) | 1981-10-16 |
Family
ID=8481439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497136A Expired ES8200092A1 (es) | 1980-11-11 | 1980-11-11 | Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4379793A (es) |
| EP (1) | EP0051981B1 (es) |
| AT (1) | ATE18208T1 (es) |
| DE (1) | DE3173904D1 (es) |
| ES (1) | ES8200092A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1210673B (it) * | 1982-02-26 | 1989-09-20 | Medosan Ind Biochimi | Antinfiammatoria amidi pirrolacetiche ad attivita' |
| IT1148117B (it) * | 1982-03-05 | 1986-11-26 | Medosan Ind Biochimi | Attivita'antiflogistica,analgesica,antipiretica,mucolitica e seda tiva della tosse dell'1 metil-5-p-tolilpirrol-2-acetato di 2'metossi-fenile |
| US4585784A (en) * | 1983-01-26 | 1986-04-29 | Mcneilab, Inc. | Pyrrole-2-acetylamino acid derivative compounds |
| IT1197688B (it) * | 1983-07-29 | 1988-12-06 | Medosan Ind Biochimi | Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
| US4187230A (en) * | 1975-05-27 | 1980-02-05 | Ethyl Corporation | Preparation of 5-aroyl-pyrrole compounds |
| US4233309A (en) * | 1977-12-06 | 1980-11-11 | Teijin Limited | Novel 1-substituted-3-acylpyrrole derivatives, platelet aggregation inhibitors containing them, as active ingredients, and processes for production of said derivatives |
-
1980
- 1980-11-11 ES ES497136A patent/ES8200092A1/es not_active Expired
-
1981
- 1981-07-20 US US06/285,341 patent/US4379793A/en not_active Expired - Fee Related
- 1981-11-04 EP EP81305251A patent/EP0051981B1/en not_active Expired
- 1981-11-04 AT AT81305251T patent/ATE18208T1/de not_active IP Right Cessation
- 1981-11-04 DE DE8181305251T patent/DE3173904D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3173904D1 (en) | 1986-04-03 |
| EP0051981A1 (en) | 1982-05-19 |
| ATE18208T1 (de) | 1986-03-15 |
| US4379793A (en) | 1983-04-12 |
| EP0051981B1 (en) | 1986-02-26 |
| ES8200092A1 (es) | 1981-10-16 |
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