DK155279C - Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater - Google Patents

Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater

Info

Publication number
DK155279C
DK155279C DK063078A DK63078A DK155279C DK 155279 C DK155279 C DK 155279C DK 063078 A DK063078 A DK 063078A DK 63078 A DK63078 A DK 63078A DK 155279 C DK155279 C DK 155279C
Authority
DK
Denmark
Prior art keywords
ingrediates
pyrrolide
oxo
hydroxy
preparing
Prior art date
Application number
DK063078A
Other languages
Danish (da)
English (en)
Other versions
DK63078A (da
DK155279B (da
Inventor
Riccardo Monguzzi
Giorgio Pifferi
Original Assignee
Isf Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa filed Critical Isf Spa
Publication of DK63078A publication Critical patent/DK63078A/da
Publication of DK155279B publication Critical patent/DK155279B/da
Application granted granted Critical
Publication of DK155279C publication Critical patent/DK155279C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK063078A 1977-02-11 1978-02-10 Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater DK155279C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2022677 1977-02-11
IT20226/77A IT1075564B (it) 1977-02-11 1977-02-11 Procedimento per la preparazione di derivati pirrolidinici

Publications (3)

Publication Number Publication Date
DK63078A DK63078A (da) 1978-08-12
DK155279B DK155279B (da) 1989-03-20
DK155279C true DK155279C (da) 1989-07-24

Family

ID=11164922

Family Applications (1)

Application Number Title Priority Date Filing Date
DK063078A DK155279C (da) 1977-02-11 1978-02-10 Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater

Country Status (23)

Country Link
US (1) US4124594A (no)
JP (1) JPS53101368A (no)
AR (1) AR219734A1 (no)
AT (1) AT362781B (no)
CA (1) CA1083585A (no)
CH (1) CH631703A5 (no)
CS (1) CS214767B2 (no)
DE (1) DE2759033C2 (no)
DK (1) DK155279C (no)
ES (1) ES466857A1 (no)
FI (1) FI66847C (no)
GB (1) GB1588074A (no)
HU (1) HU178588B (no)
IN (1) IN147764B (no)
IT (1) IT1075564B (no)
MX (1) MX4988E (no)
NL (1) NL187207C (no)
NO (1) NO147751C (no)
PL (1) PL108024B1 (no)
PT (1) PT67641B (no)
SE (1) SE428208B (no)
SU (1) SU984407A3 (no)
YU (1) YU40322B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2858573A (en) * 1958-11-04 Fibers
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1206699B (it) * 1984-02-27 1989-04-27 Isf Spa Procedimento per preparare derivati di pirrolidone.
IT1173768B (it) * 1984-04-02 1987-06-24 Isf Spa Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti
CH666483A5 (de) * 1985-01-16 1988-07-29 Lonza Ag Verfahren zur herstellung von thiotetronsaeure.
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
EP0223328B1 (en) * 1985-07-26 1992-01-29 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing oxiracetam
IL80071A0 (en) * 1985-09-24 1986-12-31 Lonza Ag Pyrrolidine acetamide derivatives
HU195773B (en) * 1985-09-24 1988-07-28 Lonza Ag Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid
CH668423A5 (de) * 1986-06-19 1988-12-30 Lonza Ag Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen.
CH668424A5 (de) * 1986-06-26 1988-12-30 Lonza Ag 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung.
CH668422A5 (de) * 1986-06-26 1988-12-30 Lonza Ag 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure.
CH667655A5 (de) * 1986-09-24 1988-10-31 Lonza Ag Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen.
CH670644A5 (no) * 1986-12-18 1989-06-30 Lonza Ag
DE58909320D1 (de) * 1988-09-06 1995-08-03 Lonza Ag Verfahren zur Herstellung von 5-Alkyltetramsäuren.
FI95034C (fi) * 1989-03-15 1995-12-11 Lonza Ag Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi
CH680293A5 (no) * 1990-06-26 1992-07-31 Lonza Ag
CN101704778B (zh) * 2009-09-30 2012-10-17 厦门市华兴化工有限公司 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法
ES2587978T3 (es) * 2010-05-21 2016-10-28 Chongqing Runze Pharmaceutical Co., Ltd. Forma cristalina de (s)-4-hidroxi-2-oxo-1-pirrolidina acetamida, método de preparación y uso de la misma
JP2019531314A (ja) 2016-10-24 2019-10-31 チョンキン ランゼ ファーマスーティカル カンパニー リミテッド 右旋性オキシラセタムの新しい結晶型、調製方法、用途
JP2019531323A (ja) * 2016-10-24 2019-10-31 チョンキン ランゼ ファーマスーティカル カンパニー リミテッド (r)−4−ヒドロキシ−2−オキソ−1−ピロリジンアセトアミドの結晶型、調製方法、用途
US10793521B2 (en) 2016-10-24 2020-10-06 Chongqing Ruzer Pharmaceutical Company Limited Crystalline form II of dextral oxiracetam, preparation method therefor and use thereof
CN108299267A (zh) * 2017-01-12 2018-07-20 重庆润泽医药有限公司 (r)-4-羟基-2-氧-1-吡咯烷乙酰胺的晶型及其制备方法和用途
CN108299268A (zh) * 2017-01-12 2018-07-20 重庆润泽医药有限公司 一种(r)-4-羟基-2-氧-1-吡咯烷乙酰胺晶型的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
AR211398Q (es) 1975-08-13 1977-12-15 Isf Spa Un procedimiento para preparar derivados de ( -pirrolin -2- on -1- il)-acilamida

Also Published As

Publication number Publication date
SU984407A3 (ru) 1982-12-23
NO147751C (no) 1983-06-08
FI66847C (fi) 1984-12-10
CA1083585A (en) 1980-08-12
FI780406A (fi) 1978-08-12
IT1075564B (it) 1985-04-22
CH631703A5 (de) 1982-08-31
PL204550A1 (pl) 1978-12-04
NO147751B (no) 1983-02-28
HU178588B (en) 1982-05-28
PT67641B (de) 1980-03-03
DE2759033A1 (de) 1978-08-17
AT362781B (de) 1981-06-10
US4124594A (en) 1978-11-07
DK63078A (da) 1978-08-12
ATA88778A (de) 1980-11-15
PT67641A (de) 1978-03-01
JPS53101368A (en) 1978-09-04
NL187207C (nl) 1991-07-01
FI66847B (fi) 1984-08-31
AR219734A1 (es) 1980-09-15
SE428208B (sv) 1983-06-13
SE7801537L (sv) 1978-08-12
DE2759033C2 (de) 1984-04-19
DK155279B (da) 1989-03-20
IN147764B (no) 1980-06-21
YU40322B (en) 1985-12-31
YU30378A (en) 1982-10-31
GB1588074A (en) 1981-04-15
NL7801501A (nl) 1978-08-15
CS214767B2 (en) 1982-05-28
NL187207B (nl) 1991-02-01
JPS6338349B2 (no) 1988-07-29
PL108024B1 (pl) 1980-03-31
NO780463L (no) 1978-08-14
ES466857A1 (es) 1978-10-01
MX4988E (es) 1983-01-31

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