DK153493C - Analogifremgangsmaade til fremstilling af androstadien-17-carboxylsyreestere samt androstadien-17-carboxylsyrer til anvendelse som mellemprodukt ved fremgangsmaaden - Google Patents

Analogifremgangsmaade til fremstilling af androstadien-17-carboxylsyreestere samt androstadien-17-carboxylsyrer til anvendelse som mellemprodukt ved fremgangsmaaden

Info

Publication number
DK153493C
DK153493C DK079077A DK79077A DK153493C DK 153493 C DK153493 C DK 153493C DK 079077 A DK079077 A DK 079077A DK 79077 A DK79077 A DK 79077A DK 153493 C DK153493 C DK 153493C
Authority
DK
Denmark
Prior art keywords
androstadia
carboxyly
analogy
acids
procedure
Prior art date
Application number
DK079077A
Other languages
Danish (da)
English (en)
Other versions
DK153493B (da
DK79077A (da
Inventor
Jaroslav Kalvoda
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK79077A publication Critical patent/DK79077A/da
Publication of DK153493B publication Critical patent/DK153493B/da
Application granted granted Critical
Publication of DK153493C publication Critical patent/DK153493C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK079077A 1976-02-24 1977-02-23 Analogifremgangsmaade til fremstilling af androstadien-17-carboxylsyreestere samt androstadien-17-carboxylsyrer til anvendelse som mellemprodukt ved fremgangsmaaden DK153493C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH225376 1976-02-24
CH225376A CH628355A5 (de) 1976-02-24 1976-02-24 Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.

Publications (3)

Publication Number Publication Date
DK79077A DK79077A (da) 1977-08-25
DK153493B DK153493B (da) 1988-07-18
DK153493C true DK153493C (da) 1988-11-28

Family

ID=4229445

Family Applications (1)

Application Number Title Priority Date Filing Date
DK079077A DK153493C (da) 1976-02-24 1977-02-23 Analogifremgangsmaade til fremstilling af androstadien-17-carboxylsyreestere samt androstadien-17-carboxylsyrer til anvendelse som mellemprodukt ved fremgangsmaaden

Country Status (26)

Country Link
US (1) US4285937A (ar)
JP (1) JPS52102264A (ar)
AT (1) AT361141B (ar)
AU (1) AU513559B2 (ar)
BE (1) BE851725A (ar)
CA (1) CA1084483A (ar)
CH (4) CH628355A5 (ar)
CY (1) CY1198A (ar)
DD (1) DD145918A5 (ar)
DE (1) DE2707336A1 (ar)
DK (1) DK153493C (ar)
ES (5) ES456134A1 (ar)
FR (2) FR2342302A1 (ar)
GB (1) GB1578243A (ar)
HK (1) HK57483A (ar)
HU (1) HU176762B (ar)
IE (1) IE45023B1 (ar)
IL (2) IL51519A (ar)
KE (1) KE3300A (ar)
MX (1) MX9203366A (ar)
MY (1) MY8500017A (ar)
NL (1) NL7701886A (ar)
NZ (1) NZ183418A (ar)
SE (1) SE436572B (ar)
SG (1) SG37383G (ar)
ZA (1) ZA771087B (ar)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
US4198403A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. 17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes
IT7967677A0 (it) * 1978-04-05 1979-03-30 Syntex Inc Erivati dell acido 4 alogeno etiani co ad azione antinfiammatoria e procedimento per la loro preparazione
DE3024008C2 (de) * 1980-06-24 1982-04-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 17α-Hydroxy-etiocarbonsäuren
US4607028A (en) * 1983-08-18 1986-08-19 Ciba-Geigy Corporation Novel carboxylic acid esters
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
AU5640390A (en) * 1989-06-16 1991-01-08 Upjohn Company, The Suramin type compounds and angiostatic steroids to inhibit angiogenesis
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US5646136A (en) * 1994-01-04 1997-07-08 Duke University Methods of inhibiting angiogenesis and tumor growth, and treating ophthalmologic conditions with angiostatic and therapeutic steroids
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
GB0015876D0 (en) * 2000-06-28 2000-08-23 Novartis Ag Organic compounds
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6777400B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
BRPI0113042B8 (pt) * 2000-08-05 2021-05-25 Glaxo Group Ltd composto da fórmula ou um seu solvato fisiologicamente aceitável, uso do mesmo, composição farmacêutica, formulação farmacêutica, método para o tratamento de um indivíduo humano ou animal com uma condição inflamatória e/ou alérgica, e, processo para preparar um composto ou um seu solvato
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6858593B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
UA77656C2 (en) * 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
BR0209271A (pt) * 2001-04-30 2004-06-15 Glaxo Group Ltd Composto, uso de um composto composição farmacêutica, formulação em aerossol farmacêutica, método para o tratamento de um paciente humano ou animal com uma condição inflamatória e/ou alérgica, e, processo para a preparação de um composto
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
JP4893305B2 (ja) * 2003-06-19 2012-03-07 ボーダー、ニコラス・エス 局所又は他の局部投与用のソフト抗炎症性ステロイドの活性及び／又は作用持続性の増強
US7419971B2 (en) * 2003-06-19 2008-09-02 Bodor Nicholas S Enhancement of activity and/or duration of action of selected anti-inflammatory steroids for topical or other local application
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
RU2008119322A (ru) * 2005-10-19 2009-11-27 Рэнбакси Лабораториз Лимитед (In) Композиции ингибиторов фосфодиэстеразы iv типа
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
US8227027B2 (en) 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
US8835410B2 (en) 2011-05-10 2014-09-16 Bodor Laboratories, Inc. Treatment of eyelid dermatitis
CN111100176A (zh) * 2019-12-20 2020-05-05 重庆华邦胜凯制药有限公司 一种化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636010A (en) * 1968-12-23 1972-01-18 Ciba Geigy Corp Esters of steroid-17-carboxylic acids
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
US4093721A (en) * 1974-08-30 1978-06-06 Glaxo Laboratories Limited Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates

Also Published As

Publication number Publication date
NL7701886A (nl) 1977-08-26
SG37383G (en) 1984-02-17
SE7701999L (sv) 1977-08-25
ES467430A1 (es) 1979-08-16
CH628641A5 (de) 1982-03-15
KE3300A (en) 1983-08-05
HK57483A (en) 1983-11-25
DE2707336C2 (ar) 1988-09-01
IE45023B1 (en) 1982-06-02
SE436572B (sv) 1985-01-07
IL51519A0 (en) 1977-04-29
HU176762B (en) 1981-05-28
DK153493B (da) 1988-07-18
NZ183418A (en) 1980-02-21
ZA771087B (en) 1978-01-25
AU2257277A (en) 1978-08-31
AT361141B (de) 1981-02-25
CH629824A5 (de) 1982-05-14
ES456134A1 (es) 1978-05-01
FR2369297A1 (fr) 1978-05-26
ES467433A1 (es) 1979-10-16
CA1084483A (en) 1980-08-26
FR2369297B1 (ar) 1981-03-06
DD145918A5 (de) 1981-01-14
IL61512A0 (en) 1980-12-31
FR2342302B1 (ar) 1981-01-09
IE45023L (en) 1977-08-24
ATA119477A (de) 1980-07-15
MX9203366A (es) 1992-09-01
IL51519A (en) 1983-03-31
JPS6139959B2 (ar) 1986-09-06
CH628355A5 (de) 1982-02-26
FR2342302A1 (fr) 1977-09-23
CH628356A5 (de) 1982-02-26
ES467432A1 (es) 1979-08-16
CY1198A (en) 1983-12-31
JPS52102264A (en) 1977-08-27
MY8500017A (en) 1985-12-31
DK79077A (da) 1977-08-25
DE2707336A1 (de) 1977-08-25
US4285937A (en) 1981-08-25
BE851725A (fr) 1977-08-23
AU513559B2 (en) 1980-12-11
ES467434A1 (es) 1979-08-16
GB1578243A (en) 1980-11-05

Similar Documents

Publication Publication Date Title
DK153493C (da) Analogifremgangsmaade til fremstilling af androstadien-17-carboxylsyreestere samt androstadien-17-carboxylsyrer til anvendelse som mellemprodukt ved fremgangsmaaden
MX149037A (es) Procedimiento mejorado para la preparacion de esteres alilicos de acidos n-alquil-omega(alquilenureido),amicos
DK59077A (da) Fremgangsmade til fremstilling af hidtil ukendte carboxyalkylacylaminosyrer
DK158346C (da) Analogifremgangsmaade til fremstilling af 4-amino-5-alkylsulfonyl-o-anisamid-derivater samt 2-methoxy-4-amino-5-alkylsulfonylbenzoesyrer til anvendelse som mellemprodukter ved fremgangsmaaden
DK189881A (da) Fremgangsmaade til fremstilling af aminocyklopentanalkensyrer eller estere deraf
DK147735C (da) Analogifremgangsmaade til fremstilling af 3-oxo-androst-4-en-17beta-thiocarboxylsyreestere
DK377777A (da) Fremgangsmaade til fremstilling af vinylsubstituerede cyclopropancarboxylsyreestere
DK149609C (da) Analogifremgangsmaade til fremstilling af hydroxyamino-alkan- eller -alkenphosphonsyrederivater eller estere eller salte deraf
DK149108C (da) Analogi-fremgangsmaade til fremstilling af 5-alkoxyimidazo(1,2-a)qoinolin-2-carboxylsyrer eller estere eller kationiske salte deraf
DK154291C (da) Analogifremgangsmaade til fremstilling af aroylpyrrolylcarboxylsyrer eller derivater deraf
DK322380A (da) Fr&mgangsmaade til fremstilling af monacolin k salte eller estere
DK151886C (da) Analogifremgangsmaade til fremstilling af (dl) eller (1) 5-benzoyl-1,2-dihydro-3h-pyrrolooe1,2-aaapyrrol-1-carboxylsyreestere
DK163580C (da) Analogifremgangsmaade til fremstilling af cyclohexancarboxylsyrederivater
NO813088L (no) Fremgangsmaate ved fremstilling av nye alkansyrer, samt estere derav
DK215079A (da) Fremgangsmaade til fremstilling af phenylaminothiothiopheneddikesyrer
DK156953C (da) Fremgangsmaade til fremstilling af phenylglyoxylsyreestere
DK146096C (da) Analogifremgangsmaade til fremstilling af 17beta-estere af testosteron
BE888336A (nl) Werkwijze ter bereinding van cyclopropaan-carbonzure esterderivaten,
DK159771C (da) Fremgangsmaade til fremstillingen af cyklopropancarboxylsyreestere
NO155663C (no) Analogifremgangsmaate ved fremstilling av nye estere av benzoxazo- og benzthiazo-2-carboxylsyre.
DK390277A (da) Fremgangsmaade til fremstilling af thiocarbaminsyreestere
DK300279A (da) Mellemprodukter til fremstilling af cyclopropancarboxylsyreestere
DK139584C (da) Fremgangsmaade til fremstilling af o,o-dialkyl-s-(n-methyl-carboxamidomethyl)-thiolphosphorsyreestere
DK300179A (da) Mellemprodukter til fremstilling af cyclopropancarboxylsyreestere
DK156954C (da) Fremgangsmaade til fremstilling af cyanoeddikesyreestere

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
AHB Application shelved due to non-payment
PUP Patent expired