DK152428C - Analogifremgangsmaade til fremstilling af 2-(aminoalkylthio)-quinolinderivater - Google Patents

Analogifremgangsmaade til fremstilling af 2-(aminoalkylthio)-quinolinderivater

Info

Publication number
DK152428C
DK152428C DK257782A DK257782A DK152428C DK 152428 C DK152428 C DK 152428C DK 257782 A DK257782 A DK 257782A DK 257782 A DK257782 A DK 257782A DK 152428 C DK152428 C DK 152428C
Authority
DK
Denmark
Prior art keywords
aminoalkylthio
preparing
quinoline derivatives
analogy procedure
analogy
Prior art date
Application number
DK257782A
Other languages
Danish (da)
English (en)
Other versions
DK257782A (da
DK152428B (da
Inventor
Thomas Paul Blackburn
Barry Cox
Allen John Guildford
David James Le Count
Robert James Pearce
Craig Willard Thornber
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of DK257782A publication Critical patent/DK257782A/da
Publication of DK152428B publication Critical patent/DK152428B/da
Application granted granted Critical
Publication of DK152428C publication Critical patent/DK152428C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
DK257782A 1981-06-09 1982-06-09 Analogifremgangsmaade til fremstilling af 2-(aminoalkylthio)-quinolinderivater DK152428C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8117642 1981-06-09
GB8117642 1981-06-09

Publications (3)

Publication Number Publication Date
DK257782A DK257782A (da) 1982-12-10
DK152428B DK152428B (da) 1988-02-29
DK152428C true DK152428C (da) 1988-08-15

Family

ID=10522379

Family Applications (1)

Application Number Title Priority Date Filing Date
DK257782A DK152428C (da) 1981-06-09 1982-06-09 Analogifremgangsmaade til fremstilling af 2-(aminoalkylthio)-quinolinderivater

Country Status (25)

Country Link
US (1) US4435405A (enExample)
EP (1) EP0066993B1 (enExample)
JP (1) JPS58965A (enExample)
AR (1) AR230437A1 (enExample)
AT (1) ATE11534T1 (enExample)
AU (1) AU556719B2 (enExample)
CA (1) CA1189077A (enExample)
CS (1) CS238624B2 (enExample)
DE (1) DE3262122D1 (enExample)
DK (1) DK152428C (enExample)
ES (3) ES512960A0 (enExample)
FI (1) FI77451C (enExample)
GR (1) GR76452B (enExample)
HU (1) HU186523B (enExample)
IE (1) IE53064B1 (enExample)
IL (1) IL65852A (enExample)
IN (1) IN158970B (enExample)
NO (1) NO161066C (enExample)
NZ (1) NZ200878A (enExample)
PH (1) PH18503A (enExample)
PL (1) PL135871B1 (enExample)
PT (1) PT75024B (enExample)
SU (1) SU1192618A3 (enExample)
YU (2) YU43269B (enExample)
ZA (1) ZA823586B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE27152T1 (de) * 1982-04-07 1987-05-15 Ici Plc Chinolin-derivate.
EP0093521B1 (en) * 1982-05-04 1988-08-24 Imperial Chemical Industries Plc Quinoline derivatives
US4585866A (en) * 1982-06-09 1986-04-29 Merrell Dow Pharmaceuticals Inc. Treatment of migraine with substituted tropyl benzoate derivatives
GB8308601D0 (en) * 1983-03-29 1983-05-05 Ici Plc Heterocyclic compounds
JPS60166406A (ja) * 1984-02-09 1985-08-29 株式会社イナックス 乾式プレス装置の坏土充填方法
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
JP2733511B2 (ja) * 1988-10-22 1998-03-30 日本臓器製薬株式会社 新規アミノアルカン誘導体
JPH03147803A (ja) * 1989-11-06 1991-06-24 Tiger Mach Seisakusho:Kk 表面多色変化模様のあるコンクリートブロックの製造方法
US6566361B2 (en) 1999-06-30 2003-05-20 Laboratories, Upsa Azapirone pain treatment
FR2795645B1 (fr) 1999-06-30 2001-09-21 Union Pharma Scient Appl Nouvelle association pharmaceutique a activite analgesique
AU7446900A (en) 1999-09-28 2001-04-30 Nihon Nohyaku Co., Ltd. Thioalkylamine derivatives and process for the preparation thereof
FR2810664B1 (fr) * 2000-06-27 2004-12-24 Adir Nouveaux composes cyclopropaniques 1,1 et 1,2-dissubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
EP2129378B1 (en) * 2007-02-28 2011-06-01 Thromboserin Limited Therapeutic compositions comprising thromboserin or a salt thereof for use in the prevention or treatment of thrombosis in a patient at risk of bleeding
EP2236511A4 (en) 2007-12-21 2011-04-13 Alla Chem Llc LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1049379B (de) 1959-01-29 Farbenfabriken Bayer Aktiengesellschaft, Leverkusen-Bayerwerk Verfahren zur Herstellung von 4 - (tert.-Aminoalkylmercapto)chinolinverbindungen
DE430960C (de) 1924-07-11 1926-06-23 J G Farbenindustrie Akt Ges Verfahren zur Darstellung von basischen AEthern von Chinolinderivaten
US1572768A (en) 1925-06-26 1926-02-09 Winthrop Chem Co Inc Pharmaceutical product
US1860286A (en) 1929-05-16 1932-05-24 Soc Of Chemical Ind Basic ethers of aryl-quinolines
GB1511390A (en) * 1975-12-04 1978-05-17 Pfizer Ltd Imidazolylalkyl sulphide antifungal agents
US4343805A (en) 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds

Also Published As

Publication number Publication date
DK257782A (da) 1982-12-10
PH18503A (en) 1985-08-02
FI77451C (fi) 1989-03-10
IL65852A0 (en) 1982-08-31
CA1189077A (en) 1985-06-18
DE3262122D1 (en) 1985-03-14
US4435405A (en) 1984-03-06
EP0066993B1 (en) 1985-01-30
FI821965A0 (fi) 1982-06-02
NO821904L (no) 1982-12-10
NZ200878A (en) 1985-02-28
NO161066B (no) 1989-03-20
HU186523B (en) 1985-08-28
IL65852A (en) 1986-04-29
ES519006A0 (es) 1984-02-01
YU123282A (en) 1985-04-30
CS425382A2 (en) 1984-02-13
ES8401034A1 (es) 1983-12-01
ES512960A0 (es) 1983-12-01
JPS58965A (ja) 1983-01-06
IE821243L (en) 1982-12-09
AU556719B2 (en) 1986-11-13
EP0066993A1 (en) 1982-12-15
YU188284A (en) 1985-10-31
ES525298A0 (es) 1985-01-16
AU8386382A (en) 1982-12-16
ATE11534T1 (de) 1985-02-15
SU1192618A3 (ru) 1985-11-15
IE53064B1 (en) 1988-05-25
ES8402576A1 (es) 1984-02-01
PT75024B (en) 1984-05-08
DK152428B (da) 1988-02-29
ZA823586B (en) 1983-03-30
YU42905B (en) 1988-12-31
PL236836A1 (en) 1983-09-12
NO161066C (no) 1989-06-28
GR76452B (enExample) 1984-08-10
FI77451B (fi) 1988-11-30
YU43269B (en) 1989-06-30
PT75024A (en) 1982-07-01
IN158970B (enExample) 1987-02-28
AR230437A1 (es) 1984-04-30
JPH0424349B2 (enExample) 1992-04-24
CS238624B2 (en) 1985-12-16
ES8502688A1 (es) 1985-01-16
PL135871B1 (en) 1985-12-31

Similar Documents

Publication Publication Date Title
DK280083D0 (da) Fremgangsmade til fremstilling af 2-(4-puridyl)-thiazolderivater
DK466681A (da) Analogifremgangmaade til fremstilling af benzo-kondenserede heterocycliske forbindelser
DK164593C (da) Analogifremgangsmaade til fremstilling af 1-phenyl-2-piperidinopropanolderivater
DK491682A (da) Fremgangsmaade til fremstilling af substituerede benzimidazoler
DK128679A (da) Fremgangsmaade til fremstilling af carbostyrilderivater
DK188683A (da) Fremgangsmaade til fremstilling af heterocycliske forbindelser
DK157019C (da) Analogifremgangsmaade til fremstilling af 2-amino-4-hydroxyquinazolinderivater
DK159442C (da) Analogifremgangsmaade til fremstilling af 6,7-substitueret-4-ethyl-quinazoliner
DK157680C (da) Analogifremgangsmaade til fremstilling af indolderivater
DK164056C (da) Analogifremgangsmaade til fremstilling af thiazol-derivater
DK357081A (da) Fremgangsmaade til fremstilling af heterocycliske forbindelser
DK162991C (da) Analogifremgangsmaade til fremstilling af thiazolidinylalkylenpiperazinderivater
DK221182A (da) Fremgangsmaade til fremstilling af chirale 2-(2-benzyl-3-mercaptopropionyl)amino-1-alkanolderivater eller chirale 2-(2-benzyl-3-mercaptopropionyl)amino-4-methylthiosmoersyrer eller faraaaceutisk acceptable salte af syrerne
DK157995C (da) Analogifremgangsmaade til fremstilling af indolderivater
DK150070C (da) Analogifremgangsmaade til fremstilling af n-dihydrothiazolyl-3-quinolincarboxamidderivater
DK153788C (da) Analogifremgangsmaade til fremstilling af 2-substituerede benzofuranderivater
DK157849C (da) Analogifremgangsmaade til fremstilling af 2-(hydroxyphenyl)-indoler
ES525298A0 (es) Procedimiento para preparar derivados de quinolina
DK312082A (da) Fremgangsmaade til fremstilling af benzothiazolsulfonamidderivater
DK156722C (da) Analogifremgangsmaade til fremstilling af 2-piperazinopyrimidinderivater
DK164403C (da) Analogifremgangsmaade til fremstilling af benzothiazolinderivater
DK152363C (da) Analogifremgangsmaade til fremstilling af 3-(omega-piperazinylalkyl)-alkylendioxybenzenderivater
DK161310C (da) Analogifremgangsmaade til fremstilling af aminopropoxyphenylderivater
DK553582A (da) Fremgangsmaade til fremstilling af naphthoxyalkylaminer
DK163000C (da) Analogifremgangsmaade til fremstilling af vinylthioacetamido-1-dethia-1-oxa-cephalosporinderivater

Legal Events

Date Code Title Description
PUP Patent expired