DK153788C - Analogifremgangsmaade til fremstilling af 2-substituerede benzofuranderivater - Google Patents

Analogifremgangsmaade til fremstilling af 2-substituerede benzofuranderivater

Info

Publication number
DK153788C
DK153788C DK501181A DK501181A DK153788C DK 153788 C DK153788 C DK 153788C DK 501181 A DK501181 A DK 501181A DK 501181 A DK501181 A DK 501181A DK 153788 C DK153788 C DK 153788C
Authority
DK
Denmark
Prior art keywords
benzofurand
derivatives
substituted
preparation
analogy procedure
Prior art date
Application number
DK501181A
Other languages
English (en)
Other versions
DK153788B (da
DK501181A (da
Inventor
Vittorio Pestellini
Mario Ghelardoni
Carlo Alberto Maggi
Gabrio Roncucci
Alberto Meli
Original Assignee
Menarini Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Sas filed Critical Menarini Sas
Publication of DK501181A publication Critical patent/DK501181A/da
Publication of DK153788B publication Critical patent/DK153788B/da
Application granted granted Critical
Publication of DK153788C publication Critical patent/DK153788C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK501181A 1980-11-12 1981-11-12 Analogifremgangsmaade til fremstilling af 2-substituerede benzofuranderivater DK153788C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT09583/80A IT1154888B (it) 1980-11-12 1980-11-12 Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione
IT958380 1980-11-12

Publications (3)

Publication Number Publication Date
DK501181A DK501181A (da) 1982-05-13
DK153788B DK153788B (da) 1988-09-05
DK153788C true DK153788C (da) 1989-01-23

Family

ID=11132470

Family Applications (1)

Application Number Title Priority Date Filing Date
DK501181A DK153788C (da) 1980-11-12 1981-11-12 Analogifremgangsmaade til fremstilling af 2-substituerede benzofuranderivater

Country Status (14)

Country Link
US (2) US4485112A (da)
JP (1) JPS57109774A (da)
BE (1) BE891092A (da)
CA (1) CA1182454A (da)
CH (1) CH653679A5 (da)
DE (1) DE3145004A1 (da)
DK (1) DK153788C (da)
ES (1) ES8307781A1 (da)
FR (1) FR2493845B1 (da)
GB (1) GB2091719B (da)
GR (1) GR76933B (da)
IT (1) IT1154888B (da)
NL (1) NL8105121A (da)
SE (1) SE451328B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2550091B1 (fr) * 1983-08-02 1986-05-23 Sanofi Sa Composition pharmaceutique ou veterinaire destinee a combattre des troubles ischemiques cardiaques contenant un derive du benzofuranne
US5087638A (en) * 1984-06-20 1992-02-11 Merck Frosst Canada, Inc. Benzofuran derivatives
CA1281325C (en) * 1984-06-20 1991-03-12 Patrice C. Belanger Benzofuran derivatives
IT1216256B (it) * 1986-08-13 1990-02-22 Menarini Sas (benzofuran-2-il) imidazoli, con attivita' farmacologica,loro sali e procedimenti di fabbricazione relativi.
US4956382A (en) * 1987-02-07 1990-09-11 Pfizer Inc. Sulfonamide anti-arrhythmic agents
US4806663A (en) * 1987-04-06 1989-02-21 The University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4851554A (en) * 1987-04-06 1989-07-25 University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
AU2543388A (en) * 1987-09-30 1989-04-18 University Of Tennessee Research Corporation, The Certain 3-substituted 2-alkyl benzothiophene derivatives
US4831156A (en) * 1987-09-30 1989-05-16 The University Of Tennessee Research Corp. 3-substituted 2-alkyl indole derivatives
US4975458A (en) * 1989-03-13 1990-12-04 Taro Pharmaceuticals Industries, Ltd. 2-alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
EP0601181A4 (en) * 1991-07-09 1994-07-27 Nippon Shinyaku Co Ltd Benzofuran derivative and pharmaceutical composition.
FR2708609B1 (fr) * 1993-07-29 1995-10-20 Sanofi Elf Dérivés de méthylguanidine, leurs procédés de préparation ainsi que les compositions en contenant.
US6417199B1 (en) * 1995-03-10 2002-07-09 Eli Lilly And Company 3-benzyl-benzothiophenes
US6395755B1 (en) * 1995-03-10 2002-05-28 Eli Lilly And Company Benzothiophene pharmaceutical compounds
US6653328B1 (en) * 1995-03-10 2003-11-25 Eli Lilly And Company 3-benzyl-benzothiophenes
EP1551392A4 (en) * 2002-09-17 2006-09-20 Arqule Inc NOVEL LAPACHO COMPOUNDS AND METHODS OF USE THEREOF
EP2447263A1 (en) 2010-09-27 2012-05-02 Bioprojet Benzazole derivatives as histamine H4 receptor ligands
WO2019195118A1 (en) * 2018-04-03 2019-10-10 Children's Hospital Medical Center Inhibitors of eya3-protein tyrosine phosphatase in dna damage repair signaling of pulmonary arterial hypertension

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3156688A (en) * 1962-11-05 1964-11-10 Abbott Lab Nu-alkyl and nu-aralkyl benzoxacycloalkanemethylamines
DE1492403A1 (de) * 1965-03-30 1969-12-04 Merck Ag E UV-Lichtschutzmittel fuer kosmetische Zwecke
GB1160925A (en) * 1967-02-08 1969-08-06 Menarini Sas 2-Substituted Benzofuran Derivatives
US3880891A (en) * 1973-09-21 1975-04-29 Smithkline Corp Substituted benzofurans
US4024273A (en) * 1974-06-20 1977-05-17 Smithkline Corporation Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity
US3983245A (en) * 1975-02-06 1976-09-28 Smithkline Corporation Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes

Also Published As

Publication number Publication date
SE451328B (sv) 1987-09-28
SE8106733L (sv) 1982-05-13
DK153788B (da) 1988-09-05
ES507072A0 (es) 1983-08-16
GB2091719A (en) 1982-08-04
CH653679A5 (it) 1986-01-15
GB2091719B (en) 1985-06-05
JPH0245629B2 (da) 1990-10-11
ES8307781A1 (es) 1983-08-16
IT8009583A0 (it) 1980-11-12
BE891092A (fr) 1982-03-01
CA1182454A (en) 1985-02-12
JPS57109774A (en) 1982-07-08
FR2493845B1 (fr) 1985-07-05
US4604392A (en) 1986-08-05
FR2493845A1 (fr) 1982-05-14
IT1154888B (it) 1987-01-21
GR76933B (da) 1984-09-04
DE3145004A1 (de) 1982-06-16
US4485112A (en) 1984-11-27
NL8105121A (nl) 1982-06-01
DK501181A (da) 1982-05-13

Similar Documents

Publication Publication Date Title
DK157876C (da) Analogifremgangsmaade til fremstilling af imidazo-rifamycin-derivater
DK155282C (da) Analogifremgangsmaade til fremstilling af carbostyrilderivater
DK157680C (da) Analogifremgangsmaade til fremstilling af indolderivater
DK534481A (da) Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater
DK164056C (da) Analogifremgangsmaade til fremstilling af thiazol-derivater
DK2281A (da) Fremgangsmaade til fremstilling af tiazolinderivater
DK149949C (da) Analogifremgangsmaade til fremstilling af n-aryl-piperazinalkanamider
DK300981A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK162524C (da) Analogifremgangsmaade til fremstilling af 5-alkylthio-tetrazolderivater
DK161581A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK157920C (da) Analogifremgangsmaade til fremstilling af indolderivater
DK150903C (da) Analogifremgangsmaade til fremstilling af benzisoselenazoloner
DK153788C (da) Analogifremgangsmaade til fremstilling af 2-substituerede benzofuranderivater
DK157995C (da) Analogifremgangsmaade til fremstilling af indolderivater
DK100281A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK146962C (da) Analogifremgangsmaade til fremstilling af indolizinderivater
DK162167C (da) Analogifremgangsmaade til fremstilling af mitosanderivater
DK564781A (da) Fremgangsmaade til fremstilling af pyrazoloindazolderivater
DK152363C (da) Analogifremgangsmaade til fremstilling af 3-(omega-piperazinylalkyl)-alkylendioxybenzenderivater
DK151256C (da) Analogifremgangsmaade til fremstilling af alkylendioxybenzenderivater
DK172181A (da) Fremgangsmaade til fremstilling af 9-carbamoyl-9-aminoalkylfluoren-derivater
DK151956C (da) Analogifremgangsmaade til fremstilling af carbostyrilderivater
DK565281A (da) Fremgangsmaade til fremstilling af quinolon-derivater
DK424781A (da) Fremgangsmaade til fremstilling af quinolonderivater
DK85281A (da) Fremgangsmaade til fremstilling af phenoxyderivater