SE8106733L - 2-substituerade bensofuran-derivat och forfarande for deras framstellning - Google Patents

2-substituerade bensofuran-derivat och forfarande for deras framstellning

Info

Publication number
SE8106733L
SE8106733L SE8106733A SE8106733A SE8106733L SE 8106733 L SE8106733 L SE 8106733L SE 8106733 A SE8106733 A SE 8106733A SE 8106733 A SE8106733 A SE 8106733A SE 8106733 L SE8106733 L SE 8106733L
Authority
SE
Sweden
Prior art keywords
group
alkyl
aryl
hydrogen atom
carbon atoms
Prior art date
Application number
SE8106733A
Other languages
English (en)
Other versions
SE451328B (sv
Inventor
V Pestellini
M Ghelardoni
C A Maggi
G Roncucci
A Meli
Original Assignee
Menarini Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Sas filed Critical Menarini Sas
Publication of SE8106733L publication Critical patent/SE8106733L/sv
Publication of SE451328B publication Critical patent/SE451328B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8106733A 1980-11-12 1981-11-12 2-substituerade bensofuranderivat, forfarande for deras framstellning samt farmaceutiska kompositioner innehallande nemnda derivat SE451328B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT09583/80A IT1154888B (it) 1980-11-12 1980-11-12 Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione

Publications (2)

Publication Number Publication Date
SE8106733L true SE8106733L (sv) 1982-05-13
SE451328B SE451328B (sv) 1987-09-28

Family

ID=11132470

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8106733A SE451328B (sv) 1980-11-12 1981-11-12 2-substituerade bensofuranderivat, forfarande for deras framstellning samt farmaceutiska kompositioner innehallande nemnda derivat

Country Status (14)

Country Link
US (2) US4485112A (sv)
JP (1) JPS57109774A (sv)
BE (1) BE891092A (sv)
CA (1) CA1182454A (sv)
CH (1) CH653679A5 (sv)
DE (1) DE3145004A1 (sv)
DK (1) DK153788C (sv)
ES (1) ES8307781A1 (sv)
FR (1) FR2493845B1 (sv)
GB (1) GB2091719B (sv)
GR (1) GR76933B (sv)
IT (1) IT1154888B (sv)
NL (1) NL8105121A (sv)
SE (1) SE451328B (sv)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2550091B1 (fr) * 1983-08-02 1986-05-23 Sanofi Sa Composition pharmaceutique ou veterinaire destinee a combattre des troubles ischemiques cardiaques contenant un derive du benzofuranne
US5087638A (en) * 1984-06-20 1992-02-11 Merck Frosst Canada, Inc. Benzofuran derivatives
CA1281325C (en) * 1984-06-20 1991-03-12 Patrice C. Belanger Benzofuran derivatives
IT1216256B (it) * 1986-08-13 1990-02-22 Menarini Sas (benzofuran-2-il) imidazoli, con attivita' farmacologica,loro sali e procedimenti di fabbricazione relativi.
US4956382A (en) * 1987-02-07 1990-09-11 Pfizer Inc. Sulfonamide anti-arrhythmic agents
US4851554A (en) * 1987-04-06 1989-07-25 University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4806663A (en) * 1987-04-06 1989-02-21 The University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4831156A (en) * 1987-09-30 1989-05-16 The University Of Tennessee Research Corp. 3-substituted 2-alkyl indole derivatives
AU2543388A (en) * 1987-09-30 1989-04-18 University Of Tennessee Research Corporation, The Certain 3-substituted 2-alkyl benzothiophene derivatives
US4975458A (en) * 1989-03-13 1990-12-04 Taro Pharmaceuticals Industries, Ltd. 2-alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
US5432195A (en) * 1991-07-09 1995-07-11 Nippon Shinyaku Company Limited Benzofuran derivative and pharmaceutical composition
FR2708609B1 (fr) * 1993-07-29 1995-10-20 Sanofi Elf Dérivés de méthylguanidine, leurs procédés de préparation ainsi que les compositions en contenant.
US6417199B1 (en) * 1995-03-10 2002-07-09 Eli Lilly And Company 3-benzyl-benzothiophenes
US6653328B1 (en) * 1995-03-10 2003-11-25 Eli Lilly And Company 3-benzyl-benzothiophenes
US6395755B1 (en) * 1995-03-10 2002-05-28 Eli Lilly And Company Benzothiophene pharmaceutical compounds
AU2003275056A1 (en) * 2002-09-17 2004-04-08 Arqule, Inc. Novel lapacho compounds and methods of use thereof
EP2447263A1 (en) * 2010-09-27 2012-05-02 Bioprojet Benzazole derivatives as histamine H4 receptor ligands
US20210130312A1 (en) * 2018-04-03 2021-05-06 Children's Hospital Medical Center Inhibitors of eya3-protein tyrosine phosphatase in dna damage repair signaling of pulmonary arterial hypertension

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3156688A (en) * 1962-11-05 1964-11-10 Abbott Lab Nu-alkyl and nu-aralkyl benzoxacycloalkanemethylamines
DE1492403A1 (de) * 1965-03-30 1969-12-04 Merck Ag E UV-Lichtschutzmittel fuer kosmetische Zwecke
GB1160925A (en) * 1967-02-08 1969-08-06 Menarini Sas 2-Substituted Benzofuran Derivatives
US3880891A (en) * 1973-09-21 1975-04-29 Smithkline Corp Substituted benzofurans
US4024273A (en) * 1974-06-20 1977-05-17 Smithkline Corporation Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity
US3983245A (en) * 1975-02-06 1976-09-28 Smithkline Corporation Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes

Also Published As

Publication number Publication date
DE3145004A1 (de) 1982-06-16
CA1182454A (en) 1985-02-12
DK153788B (da) 1988-09-05
CH653679A5 (it) 1986-01-15
JPH0245629B2 (sv) 1990-10-11
NL8105121A (nl) 1982-06-01
GB2091719B (en) 1985-06-05
BE891092A (fr) 1982-03-01
DK501181A (da) 1982-05-13
GR76933B (sv) 1984-09-04
FR2493845A1 (fr) 1982-05-14
GB2091719A (en) 1982-08-04
US4604392A (en) 1986-08-05
SE451328B (sv) 1987-09-28
IT1154888B (it) 1987-01-21
DK153788C (da) 1989-01-23
FR2493845B1 (fr) 1985-07-05
US4485112A (en) 1984-11-27
IT8009583A0 (it) 1980-11-12
ES507072A0 (es) 1983-08-16
ES8307781A1 (es) 1983-08-16
JPS57109774A (en) 1982-07-08

Similar Documents

Publication Publication Date Title
SE8106733L (sv) 2-substituerade bensofuran-derivat och forfarande for deras framstellning
DK164451C (da) 3-aminoquinolinderivat
SE7710873L (sv) Nya 1h-pyrazolo(3,4-b)pyridiner
ES466366A1 (es) Un procedimiento para preparar derivados de metasulfonamido-benzamida.
NO854677L (no) Fremgangsmaate for fremstilling av 5-alkyl-1-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
NO822948L (no) Analogifremgangsmaate for fremstilling av heterocykliske forbindelser.
ES8203867A1 (es) Procedimiento para la obtencion de derivados de benzotiazol
SE8006953L (sv) Heterocykliska foreningar
SE8302379D0 (sv) Ergolinderivat
ES8400743A1 (es) "procedimiento para la preparacion de compuestos de 1-fenilindazol-3-ona".
NZ218359A (en) Pyridine derivatives and pharmaceutical compositions
JPS5594365A (en) Novel 44aminopyridine compound
GB2004885A (en) Indolopyrones
ES8407479A1 (es) Un metodo para la preparacion de 5,6-dihidro-11h-dibenzo-(b,e)-azepin-6-onas.
SE7606497L (sv) Substituerade 4-fenylimidazoliner, deras syraadditinossalter och forfarande for framstellning derav
SE8405338A (sv) (1,3)oxazino (4,3-a) isokinolinderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande dem
DE3060217D1 (en) Penicillins, their salts, process for their preparation and therapeutic agents containing these compounds
ES500108A0 (es) Procedimiento para preparar nuevas benzotiopirano (2,3-c)pi-ridinas

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8106733-2

Effective date: 19910611

Format of ref document f/p: F