IT8009583A0 - Sostituiti e relativi metodi di derivati del benzofurano 2preparazione - Google Patents
Sostituiti e relativi metodi di derivati del benzofurano 2preparazioneInfo
- Publication number
- IT8009583A0 IT8009583A0 IT8009583A IT958380A IT8009583A0 IT 8009583 A0 IT8009583 A0 IT 8009583A0 IT 8009583 A IT8009583 A IT 8009583A IT 958380 A IT958380 A IT 958380A IT 8009583 A0 IT8009583 A0 IT 8009583A0
- Authority
- IT
- Italy
- Prior art keywords
- benzophuran
- substitutes
- derivatives
- preparation
- related methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT09583/80A IT1154888B (it) | 1980-11-12 | 1980-11-12 | Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione |
GB8107130A GB2091719B (en) | 1980-11-12 | 1981-03-06 | Benzofuran derivatives |
DE19813145004 DE3145004A1 (de) | 1980-11-12 | 1981-11-12 | 2-substituierte benzofuranderivate |
DK501181A DK153788C (da) | 1980-11-12 | 1981-11-12 | Analogifremgangsmaade til fremstilling af 2-substituerede benzofuranderivater |
FR8121192A FR2493845B1 (fr) | 1980-11-12 | 1981-11-12 | Derives de benzofuranne-2 substitues utiles comme medicaments et procedes de preparation |
NL8105121A NL8105121A (nl) | 1980-11-12 | 1981-11-12 | Op de plaats 2 gesubstitueerde benzofuranderivaten en werkwijzen ter bereiding daarvan. |
GR66504A GR76933B (it) | 1980-11-12 | 1981-11-12 | |
CA000389931A CA1182454A (en) | 1980-11-12 | 1981-11-12 | 2-substituted benzofuran derivatives and methods of preparation |
CH7276/81A CH653679A5 (it) | 1980-11-12 | 1981-11-12 | Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione. |
BE0/206522A BE891092A (fr) | 1980-11-12 | 1981-11-12 | Derives de benzofuranne-2 substitues utiles comme medicaments et procede de leur preparation |
SE8106733A SE451328B (sv) | 1980-11-12 | 1981-11-12 | 2-substituerade bensofuranderivat, forfarande for deras framstellning samt farmaceutiska kompositioner innehallande nemnda derivat |
JP56180430A JPS57109774A (en) | 1980-11-12 | 1981-11-12 | 2-substituted benzfuran derivative, manufacture and medicinal composition containing same |
ES507072A ES507072A0 (es) | 1980-11-12 | 1981-11-12 | Procedimiento para la preparacion de derivados de benzofura-no 2-sustituidos. |
US06/468,869 US4485112A (en) | 1980-11-12 | 1983-02-22 | N-[(Benzofuran-2-yl)(phenyl)methyl]-alkylene diamines useful in treating arrhythmic, histaminic and tussive conditions |
US06/641,606 US4604392A (en) | 1980-11-12 | 1984-08-17 | 2-substituted benzofuran derivatives useful in treating cardiac arrhythmic, histaminic and tussive conditions |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT09583/80A IT1154888B (it) | 1980-11-12 | 1980-11-12 | Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8009583A0 true IT8009583A0 (it) | 1980-11-12 |
IT1154888B IT1154888B (it) | 1987-01-21 |
Family
ID=11132470
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT09583/80A IT1154888B (it) | 1980-11-12 | 1980-11-12 | Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione |
Country Status (14)
Country | Link |
---|---|
US (2) | US4485112A (it) |
JP (1) | JPS57109774A (it) |
BE (1) | BE891092A (it) |
CA (1) | CA1182454A (it) |
CH (1) | CH653679A5 (it) |
DE (1) | DE3145004A1 (it) |
DK (1) | DK153788C (it) |
ES (1) | ES507072A0 (it) |
FR (1) | FR2493845B1 (it) |
GB (1) | GB2091719B (it) |
GR (1) | GR76933B (it) |
IT (1) | IT1154888B (it) |
NL (1) | NL8105121A (it) |
SE (1) | SE451328B (it) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2550091B1 (fr) * | 1983-08-02 | 1986-05-23 | Sanofi Sa | Composition pharmaceutique ou veterinaire destinee a combattre des troubles ischemiques cardiaques contenant un derive du benzofuranne |
CA1281325C (en) * | 1984-06-20 | 1991-03-12 | Patrice C. Belanger | Benzofuran derivatives |
US5087638A (en) * | 1984-06-20 | 1992-02-11 | Merck Frosst Canada, Inc. | Benzofuran derivatives |
IT1216256B (it) * | 1986-08-13 | 1990-02-22 | Menarini Sas | (benzofuran-2-il) imidazoli, con attivita' farmacologica,loro sali e procedimenti di fabbricazione relativi. |
US4956382A (en) * | 1987-02-07 | 1990-09-11 | Pfizer Inc. | Sulfonamide anti-arrhythmic agents |
US4851554A (en) * | 1987-04-06 | 1989-07-25 | University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
US4806663A (en) * | 1987-04-06 | 1989-02-21 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
US4831156A (en) * | 1987-09-30 | 1989-05-16 | The University Of Tennessee Research Corp. | 3-substituted 2-alkyl indole derivatives |
WO1989002893A1 (en) * | 1987-09-30 | 1989-04-06 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzothiophene derivatives |
US4975458A (en) * | 1989-03-13 | 1990-12-04 | Taro Pharmaceuticals Industries, Ltd. | 2-alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia |
AU2274292A (en) * | 1991-07-09 | 1993-02-11 | Nippon Shinyaku Co. Ltd. | Benzofuran derivative and pharmaceutical composition |
FR2708609B1 (fr) * | 1993-07-29 | 1995-10-20 | Sanofi Elf | Dérivés de méthylguanidine, leurs procédés de préparation ainsi que les compositions en contenant. |
US6395755B1 (en) * | 1995-03-10 | 2002-05-28 | Eli Lilly And Company | Benzothiophene pharmaceutical compounds |
US6653328B1 (en) * | 1995-03-10 | 2003-11-25 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
US6417199B1 (en) * | 1995-03-10 | 2002-07-09 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
US20060142271A1 (en) * | 2002-09-17 | 2006-06-29 | Klaus Muller | Novel lapacho compounds and methods of use thereof |
EP2447263A1 (en) * | 2010-09-27 | 2012-05-02 | Bioprojet | Benzazole derivatives as histamine H4 receptor ligands |
US20210130312A1 (en) * | 2018-04-03 | 2021-05-06 | Children's Hospital Medical Center | Inhibitors of eya3-protein tyrosine phosphatase in dna damage repair signaling of pulmonary arterial hypertension |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3156688A (en) * | 1962-11-05 | 1964-11-10 | Abbott Lab | Nu-alkyl and nu-aralkyl benzoxacycloalkanemethylamines |
DE1492403A1 (de) * | 1965-03-30 | 1969-12-04 | Merck Ag E | UV-Lichtschutzmittel fuer kosmetische Zwecke |
GB1160925A (en) * | 1967-02-08 | 1969-08-06 | Menarini Sas | 2-Substituted Benzofuran Derivatives |
US3880891A (en) * | 1973-09-21 | 1975-04-29 | Smithkline Corp | Substituted benzofurans |
US4024273A (en) * | 1974-06-20 | 1977-05-17 | Smithkline Corporation | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity |
US3983245A (en) * | 1975-02-06 | 1976-09-28 | Smithkline Corporation | Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes |
-
1980
- 1980-11-12 IT IT09583/80A patent/IT1154888B/it active
-
1981
- 1981-03-06 GB GB8107130A patent/GB2091719B/en not_active Expired
- 1981-11-12 CA CA000389931A patent/CA1182454A/en not_active Expired
- 1981-11-12 BE BE0/206522A patent/BE891092A/fr not_active IP Right Cessation
- 1981-11-12 NL NL8105121A patent/NL8105121A/nl not_active Application Discontinuation
- 1981-11-12 DE DE19813145004 patent/DE3145004A1/de not_active Withdrawn
- 1981-11-12 SE SE8106733A patent/SE451328B/sv not_active IP Right Cessation
- 1981-11-12 ES ES507072A patent/ES507072A0/es active Granted
- 1981-11-12 DK DK501181A patent/DK153788C/da active
- 1981-11-12 CH CH7276/81A patent/CH653679A5/it not_active IP Right Cessation
- 1981-11-12 GR GR66504A patent/GR76933B/el unknown
- 1981-11-12 JP JP56180430A patent/JPS57109774A/ja active Granted
- 1981-11-12 FR FR8121192A patent/FR2493845B1/fr not_active Expired
-
1983
- 1983-02-22 US US06/468,869 patent/US4485112A/en not_active Expired - Fee Related
-
1984
- 1984-08-17 US US06/641,606 patent/US4604392A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA1182454A (en) | 1985-02-12 |
GB2091719B (en) | 1985-06-05 |
DE3145004A1 (de) | 1982-06-16 |
GR76933B (it) | 1984-09-04 |
DK501181A (da) | 1982-05-13 |
SE451328B (sv) | 1987-09-28 |
NL8105121A (nl) | 1982-06-01 |
SE8106733L (sv) | 1982-05-13 |
JPS57109774A (en) | 1982-07-08 |
US4604392A (en) | 1986-08-05 |
FR2493845A1 (fr) | 1982-05-14 |
FR2493845B1 (fr) | 1985-07-05 |
BE891092A (fr) | 1982-03-01 |
ES8307781A1 (es) | 1983-08-16 |
US4485112A (en) | 1984-11-27 |
GB2091719A (en) | 1982-08-04 |
IT1154888B (it) | 1987-01-21 |
CH653679A5 (it) | 1986-01-15 |
DK153788C (da) | 1989-01-23 |
ES507072A0 (es) | 1983-08-16 |
DK153788B (da) | 1988-09-05 |
JPH0245629B2 (it) | 1990-10-11 |
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