DK151273C - Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a. - Google Patents

Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a.

Info

Publication number
DK151273C
DK151273C DK145481A DK145481A DK151273C DK 151273 C DK151273 C DK 151273C DK 145481 A DK145481 A DK 145481A DK 145481 A DK145481 A DK 145481A DK 151273 C DK151273 C DK 151273C
Authority
DK
Denmark
Prior art keywords
biosynthese
cholesterol
inhibitor
procedure
preparation
Prior art date
Application number
DK145481A
Other languages
Danish (da)
English (en)
Other versions
DK145481A (da
DK151273B (da
Inventor
Aiya Sato
Akira Terahara
Yoshio Tsujita
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12604367&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK151273(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of DK145481A publication Critical patent/DK145481A/da
Priority to DK542085A priority Critical patent/DK159439C/da
Publication of DK151273B publication Critical patent/DK151273B/da
Application granted granted Critical
Publication of DK151273C publication Critical patent/DK151273C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK145481A 1980-03-31 1981-03-31 Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a. DK151273C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK542085A DK159439C (da) 1980-03-31 1985-11-22 Analogifremgangsmaade til fremstilling af cholesterolsynteseinhibitorer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55041292A JPH0692381B2 (ja) 1980-03-31 1980-03-31 Ｍｂ−５３０ａ誘導体
JP4129280 1980-03-31

Publications (3)

Publication Number Publication Date
DK145481A DK145481A (da) 1981-10-01
DK151273B DK151273B (da) 1987-11-16
DK151273C true DK151273C (da) 1988-07-04

Family

ID=12604367

Family Applications (3)

Application Number Title Priority Date Filing Date
DK145481A DK151273C (da) 1980-03-31 1981-03-31 Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a.
DK032190A DK167805B1 (da) 1980-03-31 1990-02-07 Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer
DK032290A DK32290D0 (da) 1980-03-31 1990-02-07 Anvendelse af 8'-acylerede derivater af mellemproduktforbindelsen mb-530a til fremstilling af et laegemiddel til behandling af hypercholesterolaemi

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK032190A DK167805B1 (da) 1980-03-31 1990-02-07 Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer
DK032290A DK32290D0 (da) 1980-03-31 1990-02-07 Anvendelse af 8'-acylerede derivater af mellemproduktforbindelsen mb-530a til fremstilling af et laegemiddel til behandling af hypercholesterolaemi

Country Status (15)

Country Link
JP (1) JPH0692381B2 (enrdf_load_html_response)
AT (1) ATA150781A (enrdf_load_html_response)
AU (1) AU6893281A (enrdf_load_html_response)
BE (1) BE888214A (enrdf_load_html_response)
CH (1) CH646966A5 (enrdf_load_html_response)
DE (2) DE3112566A1 (enrdf_load_html_response)
DK (3) DK151273C (enrdf_load_html_response)
FI (1) FI810991L (enrdf_load_html_response)
FR (1) FR2479222A1 (enrdf_load_html_response)
GB (1) GB2073193A (enrdf_load_html_response)
IE (1) IE52367B1 (enrdf_load_html_response)
IT (1) IT1144325B (enrdf_load_html_response)
MX (1) MX9203567A (enrdf_load_html_response)
NL (1) NL8101592A (enrdf_load_html_response)
SE (1) SE461590B (enrdf_load_html_response)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
EP0215665B1 (en) * 1985-09-13 1991-11-21 Sankyo Company Limited Hydroxy-ml-236b derivatives, their preparation and use
US4997848A (en) * 1987-10-27 1991-03-05 Sankyo Company, Limited Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
US5075327A (en) * 1988-08-10 1991-12-24 Hoffmann-La Roche Inc. Antipsoriatic agents
US5200549A (en) * 1988-11-14 1993-04-06 Hoffman-La Roche Inc. Antipsoriatic agents
US5021451A (en) * 1988-11-14 1991-06-04 Hoffman-La Roche Inc. Method for inhibiting hyperproliferative diseases
US5073568A (en) * 1988-11-14 1991-12-17 Hoffmann-La Roche Inc. Antipsoriatic agents
US5159104A (en) * 1991-05-01 1992-10-27 Merck & Co., Inc. Process to simvastatin ester
FR2937537A1 (fr) 2008-10-29 2010-04-30 Centre Nat Rech Scient Nanoparticules de statine
KR101820099B1 (ko) 2013-01-18 2018-01-18 에스프린팅솔루션 주식회사 저항 발열체, 이를 채용한 가열 부재, 및 정착 장치
CN111788196A (zh) * 2018-01-09 2020-10-16 配体药物公司 缩醛化合物及其治疗用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (enrdf_load_html_response) * 1974-06-07 1981-03-18
JPS5925599B2 (ja) * 1979-02-20 1984-06-19 三共株式会社 新生理活性物質モナコリンｋおよびその製造法
IL60219A (en) * 1979-06-15 1985-05-31 Merck & Co Inc Hypocholesteremic fermentation products of the hmg-coa reductase inhibitor type,their preparation and pharmaceutical compositions containing them
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
ZA81703B (en) * 1980-02-04 1982-09-29 Merck & Co Inc New antihypercholesterolemic compounds,intermediates and processes
US4282155A (en) * 1980-02-04 1981-08-04 Merck & Co., Inc. Antihypercholesterolemic compounds
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics

Also Published As

Publication number Publication date
DK145481A (da) 1981-10-01
JPH0692381B2 (ja) 1994-11-16
IE52367B1 (en) 1987-09-30
IE810698L (en) 1981-09-30
DE3112566A1 (de) 1982-03-11
FR2479222A1 (fr) 1981-10-02
JPS56138181A (en) 1981-10-28
MX9203567A (es) 1992-09-01
IT8167438A0 (it) 1981-03-30
DK32290A (da) 1990-02-07
DE3112566C2 (enrdf_load_html_response) 1990-04-05
SE461590B (sv) 1990-03-05
IT1144325B (it) 1986-10-29
AU6893281A (en) 1981-10-08
DK32190D0 (da) 1990-02-07
ATA150781A (de) 1983-03-15
DK167805B1 (da) 1993-12-20
BE888214A (fr) 1981-09-30
DE3153666C2 (de) 1993-11-11
DK32190A (da) 1990-02-07
GB2073193A (en) 1981-10-14
FI810991A7 (fi) 1981-10-01
CH646966A5 (de) 1984-12-28
NL8101592A (nl) 1981-10-16
FI810991L (fi) 1981-10-01
FR2479222B1 (enrdf_load_html_response) 1983-08-26
DK32290D0 (da) 1990-02-07
DK151273B (da) 1987-11-16
SE8102047L (sv) 1981-10-01

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PUP Patent expired