DK150504C - Trijodisoftalsyrederivater til anvendelse som roentgenkontrastmidler samt radiologiske praeparater indeholdende disse - Google Patents

Trijodisoftalsyrederivater til anvendelse som roentgenkontrastmidler samt radiologiske praeparater indeholdende disse

Info

Publication number
DK150504C
DK150504C DK258477A DK258477A DK150504C DK 150504 C DK150504 C DK 150504C DK 258477 A DK258477 A DK 258477A DK 258477 A DK258477 A DK 258477A DK 150504 C DK150504 C DK 150504C
Authority
DK
Denmark
Prior art keywords
xentic
trijodisophylic
contractors
radiological
acid derivatives
Prior art date
Application number
DK258477A
Other languages
Danish (da)
English (en)
Other versions
DK150504B (da
DK258477A (da
Inventor
Vegard Nordal
Hugo Holtermann
Original Assignee
Nyegaard & Co As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nyegaard & Co As filed Critical Nyegaard & Co As
Publication of DK258477A publication Critical patent/DK258477A/da
Publication of DK150504B publication Critical patent/DK150504B/da
Application granted granted Critical
Publication of DK150504C publication Critical patent/DK150504C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK258477A 1976-06-11 1977-06-10 Trijodisoftalsyrederivater til anvendelse som roentgenkontrastmidler samt radiologiske praeparater indeholdende disse DK150504C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB24338/76A GB1548594A (en) 1976-06-11 1976-06-11 Triiodoisophthalic acid amides
GB2433876 1976-06-11

Publications (3)

Publication Number Publication Date
DK258477A DK258477A (da) 1977-12-12
DK150504B DK150504B (da) 1987-03-16
DK150504C true DK150504C (da) 1988-01-11

Family

ID=10210154

Family Applications (1)

Application Number Title Priority Date Filing Date
DK258477A DK150504C (da) 1976-06-11 1977-06-10 Trijodisoftalsyrederivater til anvendelse som roentgenkontrastmidler samt radiologiske praeparater indeholdende disse

Country Status (11)

Country Link
US (1) US4250113A (xx)
JP (1) JPS5321137A (xx)
BE (1) BE855580A (xx)
CH (1) CH630064A5 (xx)
DE (1) DE2726196C2 (xx)
DK (1) DK150504C (xx)
FR (1) FR2354316A1 (xx)
GB (1) GB1548594A (xx)
HK (1) HK56683A (xx)
NL (1) NL175814C (xx)
SE (1) SE441181B (xx)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4278654A (en) * 1978-07-04 1981-07-14 Nyegaard & Co. A/S Process for the preparation of a sterile injectable physiologically acceptable solution of an X-ray contrast agent and solutions of the X-ray contrast agent and a buffer
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
US4256729A (en) * 1979-03-23 1981-03-17 Mallinckrodt, Inc. N,N'-Bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-keto-L-gulonamido)isophthalamide and radiological compositions containing same
DE2928417A1 (de) * 1979-07-12 1981-01-29 Schering Ag Trijodierte basen
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3001292A1 (de) * 1980-01-11 1981-07-16 Schering Ag Berlin Und Bergkamen, 1000 Berlin Nichtionische 5-c-substituierte 2,4,6-trijod-isophthalsaeure-derivate
DE3038853A1 (de) 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
JPS58102200A (ja) * 1981-12-14 1983-06-17 日本原子力事業株式会社 沈降分離槽
DE3150916A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
DK162045C (da) * 1982-10-01 1992-02-10 Nyegaard & Co As Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser
US5204086A (en) * 1982-10-01 1993-04-20 Nycomed Imaging As X-ray contrast agent
NO161368C (no) * 1982-11-08 1989-08-09 Nyegaard & Co As Roentgenkontrastmidler samt radiologiske preparater derav.
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
US5191119A (en) * 1983-10-20 1993-03-02 Cook Imaging Corp. Process for producing non-ionic radiographic contrast media utilizing N-allylation
JPS6091807U (ja) * 1983-11-30 1985-06-22 松下電器産業株式会社 テ−ブル
JPS634809Y2 (xx) * 1984-10-04 1988-02-08
US4954348A (en) * 1985-08-09 1990-09-04 Cook Imaging Corporation Non-ionic polyol contrast media from ionic contrast media
US5035877A (en) * 1985-08-09 1991-07-30 Cook Imaging Corporation Non-ionic contrast media from ionic contrast media
EP0233249B1 (en) * 1985-08-09 1993-11-24 Cook Imaging Corporation Non-ionic polyol contrast media from ionic contrast media
JPH0637447B2 (ja) * 1987-10-31 1994-05-18 東洋紡績株式会社 新規アミド化合物
US5698739A (en) * 1989-07-05 1997-12-16 Schering Aktiengesellschaft Carboxamide non-ionic contrast media
GB8919929D0 (en) 1989-09-04 1989-10-18 Nycomed As Compositions
DE3937118A1 (de) * 1989-11-03 1991-05-08 Schering Ag Nichtionische roentgenkontrastmittel mit hohem jodgehalt
US5232685A (en) * 1989-11-03 1993-08-03 Schering Aktiengesellschaft Nonionic x-ray contrast medium with high iodine content
CA2029830A1 (en) * 1989-11-29 1991-05-30 Ramachandran S. Ranganathan Nonionic radiographic contrast agents
US5869024A (en) * 1989-11-29 1999-02-09 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
US5191120A (en) * 1989-12-13 1993-03-02 Mallinckrodt Medical, Inc. Process for preparing nonionic X-ray contrast agents
US4997983A (en) * 1990-01-31 1991-03-05 Mallinckrodt, Inc. Process for production of ioversol
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5356613A (en) * 1991-03-18 1994-10-18 Mallinckrodt Medical, Inc. X-ray contrast agents, compositions and methods
DE4109169A1 (de) * 1991-03-20 1992-09-24 Koehler Chemie Dr Franz Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung
US5169864A (en) * 1991-11-15 1992-12-08 Baxter International Inc. Unbuffered premixed ranitidine formulation
EP0619744A4 (en) * 1991-12-03 1995-02-08 Mallinckrodt Medical Inc NON-IONIC RADIOGRAPHIC CONTRAST METHODS, COMPOSITIONS AND AGENTS.
US5278311A (en) * 1992-06-05 1994-01-11 E. R. Squibb & Sons, Inc. Nonionic radiographic contrast agents
WO1994005337A1 (en) * 1992-09-02 1994-03-17 Mallinckrodt Medical, Inc. Nonionic x-ray contrast agents, compositions and methods
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol
US5665331A (en) * 1995-01-10 1997-09-09 Nanosystems L.L.C. Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers
US5716642A (en) * 1995-01-10 1998-02-10 Nano Systems L.L.C. Microprecipitation of nanoparticulate pharmaceutical agents using surface active material derived from similar pharmaceutical agents
US5560932A (en) * 1995-01-10 1996-10-01 Nano Systems L.L.C. Microprecipitation of nanoparticulate pharmaceutical agents
US5662883A (en) * 1995-01-10 1997-09-02 Nanosystems L.L.C. Microprecipitation of micro-nanoparticulate pharmaceutical agents
US5543133A (en) * 1995-02-14 1996-08-06 Nanosystems L.L.C. Process of preparing x-ray contrast compositions containing nanoparticles
DE19510864A1 (de) * 1995-03-16 1996-09-19 Schering Ag Röntgenkontrastmittel für die Computertomographie und Urographie
IT1275429B (it) * 1995-05-18 1997-08-07 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di composti organici
CN1078201C (zh) * 1995-11-20 2002-01-23 江苏省原子医学研究所 一种碘海醇的制备方法
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US5840967A (en) * 1996-08-29 1998-11-24 Nycomed Imaging As Process for the preparation of contrast agents
GB9618055D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US5705692A (en) * 1996-09-27 1998-01-06 Abbott Laboratories Process for the preparation of iohexol
PT101919B (pt) * 1996-09-30 2000-01-31 Hovione Sociedade Quimica Sa Um processo para a purificacao de tohexol
US5861138A (en) * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Ligands for MRI contrast agent
US5861140A (en) * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Tripodal paramagnetic contrast agents for MR imaging
US5824821A (en) * 1997-02-07 1998-10-20 Nycomed Imaging As Process for the preparation of iodinated contrast agents and intermediates therefor
US5847212A (en) * 1997-04-21 1998-12-08 Abbott Laboratories Process for the preparation of iohexol
GB9710726D0 (en) * 1997-05-23 1997-07-16 Nycomed Imaging As Compound
US6137006A (en) * 1997-05-23 2000-10-24 Nycomed Imaging As Preparation of tri-iodo benzene compounds
GB9710728D0 (en) * 1997-05-23 1997-07-16 Nycomed Imaging As Method
GB9710725D0 (en) 1997-05-23 1997-07-16 Nycomed Imaging As Process
IT1292037B1 (it) * 1997-05-30 1999-01-25 Bracco Spa Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
US5869026A (en) * 1997-08-21 1999-02-09 Hoechst Celanese Corp. Tripodal carboxamide ligands for MRI contrast agents
US5820851A (en) * 1997-08-21 1998-10-13 Hoechst Celanese Corporation Tripodal pyridine ligands as MRI contrast agents
US5824288A (en) * 1997-08-21 1998-10-20 Hoechst Celanese Corporation Thio-substituted pyridines as MRI ligand precursors
US5858329A (en) * 1997-08-21 1999-01-12 Hoechst Celanese Corporation MRI diagnostic procedures using tripodal pyridinyl metal complexes
US5869025A (en) * 1997-08-21 1999-02-09 Hoechst Celanese Corporation Tripodal aromatic heterocycle carboxamide MRI contrast agents
GB9720969D0 (en) 1997-10-02 1997-12-03 Nycomed Imaging As Process
GB9725010D0 (en) * 1997-11-26 1998-01-28 Nycomed Imaging As Process
US20040170561A1 (en) * 1998-09-08 2004-09-02 Jesse Salb Functional radiographic imaging methods and agents
US6226352B1 (en) 1998-09-08 2001-05-01 Veritas Pharmaceuticals, Inc. System and method for radiographic imaging of tissue
US6723746B2 (en) * 1998-09-08 2004-04-20 Veritas Pharmaceuticals, Inc. Functional radiographic imaging methods and agents
US6751290B2 (en) 1998-09-08 2004-06-15 Veritas Pharmaceuticals, Inc. Radiographic assessment of tissue after exposure to a compound
GB9825095D0 (en) * 1998-11-16 1999-01-13 Nycomed Imaging As Chemical process
DE60140658D1 (de) 2000-03-16 2010-01-14 Veritas Pharmaceuticals Radiographische bewertung von gewebereaktionen auf chemische verbindungen
US6660248B2 (en) 2000-11-10 2003-12-09 William Marsh Rice University Fullerene (C60)-based X-ray contrast agent for diagnostic imaging
IT1319670B1 (it) * 2000-12-01 2003-10-23 Bracco Spa Processo per la preparazione di 5-ammino-n,n'-bis(2-idrossi-1-(idrossimetil)etil))-1,3-benzendicarbossammide (i) e 5-ammino-n,n'-
ITMI20010773A1 (it) * 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
KR20030032185A (ko) * 2001-10-16 2003-04-26 동국제약 주식회사 Ｎ,ｎ'-비스[2,3-디히드록시프로필]-2,4,6-트리요오드-5-아세틸아미도 이소 프탈아미드의 결정화방법
SI1836239T1 (sl) 2005-01-13 2009-04-30 Cinv Ag Kompozitni materiali, ki vsebujejo ogljikove nanodelce
JP4801661B2 (ja) * 2005-03-18 2011-10-26 マナック株式会社 ５−アミノ−２，４，６−トリヨードイソフタル酸誘導体のアセチル化方法
PT103391B (pt) * 2005-11-24 2008-10-30 Hovione Farmaciencia S A Processo para fabrico de lohexol
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2385845A1 (en) 2009-01-09 2011-11-16 Ge Healthcare As Contrast media compositions
PL2451994T3 (pl) 2009-07-07 2014-04-30 Bracco Imaging Spa Proces wytwarzania środka jodującego
EP2277859A1 (en) * 2009-07-21 2011-01-26 GE Healthcare AS Acetylation using reduced concentration of acetic acid anhydride for synthesizing non-ionic X-ray contrast agents
EP2277851A1 (en) * 2009-07-21 2011-01-26 GE Healthcare AS Acetylation using reduced volume of acetic acid anhydride for synthesizing non-ionic X-ray contrast agents
US20110021821A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous acetylation process in synthesis of non-ionic x-ray contrast agents
US20130116554A1 (en) * 2010-07-12 2013-05-09 Ge Healthcare As X-ray imaging at low contrast agent concentrations and/or low dose radiation
CN102249948B (zh) * 2011-05-23 2014-01-29 苏州昊帆生物科技有限公司 5-乙酰氨基-n,n’-双-(2,3-二羟基丙基)-2,4,6-三碘间苯二甲酰胺的合成方法
EP2606912A1 (en) * 2011-12-23 2013-06-26 Central Medical Service Co., Ltd. Contrast medium composition with contrast enhancement effect by comprising highly concentrated agent
EP3077368B1 (en) * 2013-12-06 2018-07-11 GE Healthcare AS Alternative process for the purification of an intermediate in the synthesis of non-ionic x-ray contrast agents
WO2015082719A1 (en) * 2013-12-06 2015-06-11 Ge Healthcare As Alternative acetylation process in the synthesis of non-ionic xray contrast agents
EP3077367B1 (en) * 2013-12-06 2018-07-11 GE Healthcare AS Alternative process for the purification of an intermediate in the synthesis of non-ionic x-ray contrast agents
WO2015133651A1 (en) 2014-03-04 2015-09-11 Otsuka Pharmaceutical Co., Ltd. Iohexol powder and method of using the same
PT108524B (pt) * 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
CN107778191A (zh) * 2016-08-26 2018-03-09 正大天晴药业集团股份有限公司 一种碘普罗胺及其中间体的制备方法
RU2655619C1 (ru) * 2017-06-13 2018-05-29 Алексей Георгиевич Александров Способ получения фармацевтической субстанции на основе йогексола
CN107857714B (zh) * 2017-11-29 2020-11-13 上海司太立制药有限公司 一种碘海醇中间体杂质的制备方法和用途
CN108191690A (zh) * 2017-12-11 2018-06-22 天津河清化学工业有限公司 碘海醇节能环保的连续化制备方法
CN108191689A (zh) * 2017-12-11 2018-06-22 天津河清化学工业有限公司 一种新型碘海醇节能环保的连续化制备方法
EP4001261A1 (en) 2020-11-23 2022-05-25 Justesa Imagen S.A.U Procedure for obtaining high purity iohexol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1321591A (en) 1969-06-27 1973-06-27 Nyegaard & Co As Non-ionic iodinated x-ray contrast agents
US4021481A (en) * 1969-06-27 1977-05-03 Nyegaard & Co. A/S Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups
US3701771A (en) * 1969-06-27 1972-10-31 Nyegaard & Co As N-(2,4,6-triiodobenzoyl)-sugar amines
BE788054A (fr) * 1971-08-26 1973-02-26 Bracco Ind Chimica Spa Nouvel agent de contraste radiographique et procede pour le preparer
CH608189A5 (xx) * 1974-12-13 1978-12-29 Savac Ag

Also Published As

Publication number Publication date
SE7706792L (sv) 1977-12-12
CH630064A5 (de) 1982-05-28
US4250113A (en) 1981-02-10
DK150504B (da) 1987-03-16
DE2726196A1 (de) 1977-12-22
SE441181B (sv) 1985-09-16
NL175814C (nl) 1985-01-02
DE2726196C2 (de) 1983-12-29
FR2354316A1 (fr) 1978-01-06
HK56683A (en) 1983-11-25
JPS5654310B2 (xx) 1981-12-24
DK258477A (da) 1977-12-12
BE855580A (fr) 1977-12-12
FR2354316B1 (xx) 1982-11-12
GB1548594A (en) 1979-07-18
NL7706385A (nl) 1977-12-13
JPS5321137A (en) 1978-02-27

Similar Documents

Publication Publication Date Title
DK150504C (da) Trijodisoftalsyrederivater til anvendelse som roentgenkontrastmidler samt radiologiske praeparater indeholdende disse
NO145096C (no) Nye 5-hydroksypropionylamino-2,4,6-trijod-sioftalsyre-bis(dihydroksypropylamider) for anvendelse i roentgenkontrastmidler, fremgangsmaate for fremstilling av forbindelsene samt roentgenkontrastmidler inneholdende disse
DK20979A (da) 4-amino-5-alkylsulfonyl-0-anisamid-derivater samt fremgangsmaade til fremstilling deraf
DK148783C (da) Triiodbenzenderivater til anvendelse som roentgenkontrastmidler og roentgenkontrastmidler indeholdende saadanne forbindelser
NO142800C (no) Herbicide preparater inneholdende pyrazolderivater
SE7701181L (sv) Syreavkennare
DK472277A (da) Polymeraggregater fremgangsmaade til deres fremstilling samt belaegningskompositioner indeholdende disse polymeraggregater
NO820200L (no) Fremgangsmaate til fremstilling av fosforylforbindelser, i foerste rekke heksapyranoseforbindelser samt farmasoeytiske preparater inneholdende disse
DK116380A (da) Bradykninhaemmende tripeptidforbindelser fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
PL197552A1 (pl) Srodek chwastobojczy zawierajacy pochodne kwasu fenoksy-fenoksy-propionowego
DK258076A (da) Rifamycinforbindelser samt fremgangsmade til fremstilling heraf
DK150685C (da) Monoazopigmentblandinger samt fremgangsmaade til fremstilling deraf
DK150595C (da) Azolyl-carboxylsyre-derivater til anvendelse som fungicider, fungicide midler indeholdende disse samt anvendelse af azolyl-carboxylsyre-derivaterne
DK403577A (da) Piperazinylpyridiner til anvendelse som anoreziske midler og fremgangsmaade til fremstilling af disse forbindelser
DK231877A (da) Radioaktivt preparat samt fremgangsmade og middel til fremstilling deraf
IT7967486A0 (it) Cursore con dispositivo di bloccaggio per cerniere lampo
DK573275A (da) Substituerede propanol (2)-derivater og nikotinsyreestere deraf samt fremgangsmade til fremstilling af disse forbindelser
DK538677A (da) Isoxazolderivater fremgangsmaade til deres fremstilling og midler indeholdende disse forbindelser
DK443575A (da) 3-alkylisoxazolderivater og herbicider indeholdende disse
SE7708037L (sv) Peptidderivat, samt kompositioner innehallande dessa
DK69179A (da) Substituerede 2-phenylimino-imidazolidiner syreadditionssalte heraf samt fremgansmaade til fremstilling heraf
DK537677A (da) Propionsyrederivater samt fremgangsmaade til deres fremstilling
DK545077A (da) Thiooximcephalosporin- og penicillinderivater samt fremgangsmaader til fremstilling deraf
DK236777A (da) Benzodioxolderivater fremgangsmader til fremstilling af disse forbindelser samt herbicide midler indeholdende forbindelserne
DK495478A (da) Polysaccharid fremgangsmaade til fremstilling deraf samt hypocholesterolpraeparat indeholdende dette polysaccharid

Legal Events

Date Code Title Description
PUP Patent expired