DK1497290T3 - Fremgangsmåde til fremstilling af syresalte af gemifloxacin - Google Patents

Fremgangsmåde til fremstilling af syresalte af gemifloxacin

Info

Publication number
DK1497290T3
DK1497290T3 DK03715805T DK03715805T DK1497290T3 DK 1497290 T3 DK1497290 T3 DK 1497290T3 DK 03715805 T DK03715805 T DK 03715805T DK 03715805 T DK03715805 T DK 03715805T DK 1497290 T3 DK1497290 T3 DK 1497290T3
Authority
DK
Denmark
Prior art keywords
gemifloxacin
preparation
acid salts
salts
acid
Prior art date
Application number
DK03715805T
Other languages
Danish (da)
English (en)
Inventor
Sang-Chul Choi
Do-Hyun Nam
Bo-Seung Choi
Hoon Choi
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Application granted granted Critical
Publication of DK1497290T3 publication Critical patent/DK1497290T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
DK03715805T 2002-04-08 2003-04-04 Fremgangsmåde til fremstilling af syresalte af gemifloxacin DK1497290T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2002-0018847A KR100517638B1 (ko) 2002-04-08 2002-04-08 게미플록사신 산염의 새로운 제조방법
PCT/KR2003/000683 WO2003087100A1 (en) 2002-04-08 2003-04-04 Process for preparing acid salts of gemifloxacin

Publications (1)

Publication Number Publication Date
DK1497290T3 true DK1497290T3 (da) 2008-12-15

Family

ID=36241771

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03715805T DK1497290T3 (da) 2002-04-08 2003-04-04 Fremgangsmåde til fremstilling af syresalte af gemifloxacin

Country Status (32)

Country Link
US (1) US7361762B2 (sl)
EP (1) EP1497290B1 (sl)
JP (1) JP4315815B2 (sl)
KR (1) KR100517638B1 (sl)
CN (1) CN1291987C (sl)
AP (1) AP1786A (sl)
AT (1) ATE404559T1 (sl)
AU (1) AU2003219581B2 (sl)
BR (1) BRPI0309037B8 (sl)
CA (1) CA2481217C (sl)
CO (1) CO5611198A2 (sl)
CY (1) CY1108469T1 (sl)
DE (1) DE60322872D1 (sl)
DK (1) DK1497290T3 (sl)
EA (1) EA007222B1 (sl)
ES (1) ES2311694T3 (sl)
GE (1) GEP20074025B (sl)
HK (1) HK1074440A1 (sl)
HR (1) HRP20040929B1 (sl)
IL (1) IL164328A (sl)
IS (1) IS2731B (sl)
MA (1) MA26408A1 (sl)
MX (1) MXPA04009777A (sl)
NO (1) NO330042B1 (sl)
NZ (1) NZ536174A (sl)
OA (1) OA12801A (sl)
PL (1) PL372815A1 (sl)
PT (1) PT1497290E (sl)
SI (1) SI1497290T1 (sl)
UA (1) UA77070C2 (sl)
WO (1) WO2003087100A1 (sl)
ZA (1) ZA200408088B (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE410225T1 (de) * 2001-08-02 2008-10-15 Lg Life Sciences Ltd Verfahren zur herstellung von amino-geschützten 4-aminomethylene-pyrrolidin-3-on-derivaten, gemifloxacin und deren salze
WO2006134431A1 (en) * 2005-05-03 2006-12-21 Ranbaxy Laboratories Limited Formate salt of gemifloxacin
EP2161269A1 (en) * 2005-06-15 2010-03-10 Hetero Drugs Limited Process for the preparation of amorphous gemifloxacin
EP1993547B1 (en) * 2006-03-07 2012-08-22 Wockhardt Limited Prodrugs of benzoquinolizine-2-carboxylic acid
US20100076193A1 (en) * 2006-10-31 2010-03-25 Chandrasekaran Ramasubbu process for the preparation of gemifloxacin

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134482A (en) 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
IN162769B (sl) 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
JPH0356479A (ja) 1989-07-24 1991-03-12 Takeshi Yokota 水溶性キノロン誘導体のp‐トルエンスルホン酸塩
PL166381B1 (pl) 1989-08-16 1995-05-31 Pfizer Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
US5137892A (en) 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
US5276041A (en) 1991-11-08 1994-01-04 Kaken Pharmaceutical Co., Ltd. Oxime derivatives
JPH0673056A (ja) 1992-08-26 1994-03-15 Kaken Pharmaceut Co Ltd キノリンカルボン酸誘導体およびその塩
US5776944A (en) 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
EP0688772B1 (en) 1994-06-16 1999-05-06 LG Chemical Limited Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation
JP3449658B2 (ja) 1994-12-21 2003-09-22 杏林製薬株式会社 安定性に優れた8−アルコキシキノロンカルボン酸水和物並びにその製造方法
JP3145715B2 (ja) 1995-06-06 2001-03-12 ファイザー・インコーポレーテッド 無水7−([1α,5α,6α]−6−アミノ−3−アザビシクロ[3.1.0]ヘキサ−3−イル)−6−フルオロ−1−(2,4−ジフルオロフェニル)−1,4−ジヒドロ−4−オキソ−1,8−ナフチリディン−3−カルボン酸メタンスルホン酸塩の新規な結晶形態
TR199800208T1 (sl) 1995-08-11 1998-05-21 Pfizer Inc.
ES2198564T3 (es) 1996-03-29 2004-02-01 Smithkline Beecham Corporation Dihidrato de eprosartan y un procedimiento para su produccion y formulacion.
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
KR100286874B1 (ko) 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
DK1082300T3 (da) 1998-05-29 2003-12-15 Upjohn Co 3-[1'-N-Methylamino)ethyl-N-benzyl]pyrrolidin-monomethansulfonat
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
DK1223935T3 (da) 1999-06-29 2008-02-04 Lg Life Sciences Ltd Anvendelse af gemifloxacinforbindelser mod bakterier
EP1401440A4 (en) 1999-09-01 2006-07-05 Lg Life Sciences Ltd METHODS OF USING FLUOROQUINOLONE COMPOUNDS AGAINST BACTERIA
GB9920917D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
WO2001021176A1 (en) 1999-09-22 2001-03-29 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against bacteria
KR20010091379A (ko) 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
KR20020018560A (ko) 2000-09-01 2002-03-08 성재갑 3-아미노메틸-4-z-메톡시이미노피롤리딘의 신규 제조방법

Also Published As

Publication number Publication date
BRPI0309037B8 (pt) 2021-05-25
CA2481217C (en) 2010-06-01
HRP20040929A2 (en) 2005-02-28
DE60322872D1 (de) 2008-09-25
EP1497290A4 (en) 2006-05-10
MA26408A1 (fr) 2004-12-01
ATE404559T1 (de) 2008-08-15
AU2003219581B2 (en) 2006-08-24
WO2003087100A1 (en) 2003-10-23
BRPI0309037B1 (pt) 2018-07-31
EP1497290B1 (en) 2008-08-13
NO330042B1 (no) 2011-02-07
CN1291987C (zh) 2006-12-27
EP1497290A1 (en) 2005-01-19
AU2003219581A1 (en) 2003-10-27
UA77070C2 (uk) 2006-10-16
MXPA04009777A (es) 2004-12-13
CN1649868A (zh) 2005-08-03
HRP20040929B1 (hr) 2013-12-06
US7361762B2 (en) 2008-04-22
NZ536174A (en) 2006-09-29
EA200401328A1 (ru) 2005-06-30
BR0309037A (pt) 2005-02-01
PT1497290E (pt) 2008-11-14
JP4315815B2 (ja) 2009-08-19
IL164328A0 (en) 2005-12-18
HK1074440A1 (en) 2005-11-11
JP2005529112A (ja) 2005-09-29
KR20030080292A (ko) 2003-10-17
KR100517638B1 (ko) 2005-09-28
CA2481217A1 (en) 2003-10-23
IL164328A (en) 2009-08-03
US20050148622A1 (en) 2005-07-07
AP1786A (en) 2007-10-04
GEP20074025B (en) 2007-01-25
CO5611198A2 (es) 2006-02-28
CY1108469T1 (el) 2014-04-09
IS2731B (is) 2011-04-15
ZA200408088B (en) 2006-05-31
NO20044629L (no) 2004-10-27
IS7477A (is) 2004-09-30
OA12801A (en) 2006-07-11
PL372815A1 (en) 2005-08-08
ES2311694T3 (es) 2009-02-16
AP2004003148A0 (en) 2004-12-31
EA007222B1 (ru) 2006-08-25
SI1497290T1 (sl) 2008-12-31

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