DK149231C - Analogifremgangsmaade til fremstilling af enkephalin-analoge tetrapeptidamider eller syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af enkephalin-analoge tetrapeptidamider eller syreadditionssalte deraf

Info

Publication number
DK149231C
DK149231C DK434778A DK434778A DK149231C DK 149231 C DK149231 C DK 149231C DK 434778 A DK434778 A DK 434778A DK 434778 A DK434778 A DK 434778A DK 149231 C DK149231 C DK 149231C
Authority
DK
Denmark
Prior art keywords
analogue
tetrapeptidamides
preparation
acid addition
addition salts
Prior art date
Application number
DK434778A
Other languages
Danish (da)
English (en)
Other versions
DK434778A (da
DK149231B (da
Inventor
Jr Edward Lee Smithwick
Robert Curtis Art Frederickson
Robert Theodore Shuman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK434778A publication Critical patent/DK434778A/da
Publication of DK149231B publication Critical patent/DK149231B/da
Application granted granted Critical
Publication of DK149231C publication Critical patent/DK149231C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
DK434778A 1977-10-03 1978-10-02 Analogifremgangsmaade til fremstilling af enkephalin-analoge tetrapeptidamider eller syreadditionssalte deraf DK149231C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/838,516 US4264491A (en) 1977-10-03 1977-10-03 Analgesic compounds
US83851677 1977-10-03

Publications (3)

Publication Number Publication Date
DK434778A DK434778A (da) 1979-04-04
DK149231B DK149231B (da) 1986-03-24
DK149231C true DK149231C (da) 1986-08-18

Family

ID=25277291

Family Applications (1)

Application Number Title Priority Date Filing Date
DK434778A DK149231C (da) 1977-10-03 1978-10-02 Analogifremgangsmaade til fremstilling af enkephalin-analoge tetrapeptidamider eller syreadditionssalte deraf

Country Status (33)

Country Link
US (1) US4264491A (es)
EP (1) EP0001684B1 (es)
JP (1) JPS5459247A (es)
AR (1) AR224238A1 (es)
AT (1) AT367028B (es)
AU (1) AU520315B2 (es)
BE (1) BE870819A (es)
BG (1) BG31224A3 (es)
CA (1) CA1156219A (es)
CH (1) CH635571A5 (es)
CS (1) CS235072B2 (es)
DD (1) DD139710A5 (es)
DE (1) DE2861019D1 (es)
DK (1) DK149231C (es)
EG (1) EG13636A (es)
ES (1) ES473925A1 (es)
FI (1) FI66842C (es)
FR (1) FR2404629B1 (es)
GB (1) GB2005688B (es)
GR (1) GR71651B (es)
HU (1) HU182866B (es)
IE (1) IE47378B1 (es)
IL (1) IL55650A (es)
IT (1) IT1100839B (es)
LU (1) LU80316A1 (es)
NZ (1) NZ188521A (es)
PH (1) PH14660A (es)
PL (1) PL114271B1 (es)
PT (1) PT68598A (es)
RO (1) RO76176A (es)
SU (1) SU908246A3 (es)
YU (1) YU231578A (es)
ZA (1) ZA785564B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI770219A (es) 1976-02-02 1977-08-03 Sandoz Ag
US4331593A (en) * 1977-10-03 1982-05-25 Smithwick Jr Edward L Analgesic compounds
US4265808A (en) * 1979-12-17 1981-05-05 Eli Lilly And Company Pharmacologically active peptides
US4283330A (en) * 1979-12-17 1981-08-11 Eli Lilly And Company Pharmacologically active peptides
US4333873A (en) 1979-12-17 1982-06-08 Eli Lilly And Company Pharmacologically active peptides
JPS5692846A (en) * 1979-12-27 1981-07-27 Takeda Chem Ind Ltd Tetrapeptide derivative and its preparation
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
JPS5785349A (en) * 1980-11-14 1982-05-28 Earth Chem Corp Ltd Tripeptide alkylamide derivative
JPS5738756A (en) * 1980-08-18 1982-03-03 Earth Chem Corp Ltd Tripeptide alkylamide derivative
US4322340A (en) * 1980-10-20 1982-03-30 Eli Lilly And Company Pharmacologically active peptides
JPS5772950A (en) * 1980-10-24 1982-05-07 Takeda Chem Ind Ltd Tetrapeptide derivative, its preparation and analgesic agent
DE3267380D1 (en) * 1981-06-22 1985-12-19 Ici Plc Peptides and pseudopeptides in which the n terminus bears two substituents
US4448717A (en) * 1982-11-12 1984-05-15 Eli Lilly And Company Pharmacologically active peptides
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1042487A (en) * 1964-06-25 1966-09-14 Ici Ltd Polypeptide derivatives
DE2703109A1 (de) * 1976-01-26 1977-08-04 Wellcome Found Biologisch wirksame amide
FI770219A (es) * 1976-02-02 1977-08-03 Sandoz Ag
GB1532181A (en) * 1976-02-02 1978-11-15 Beckman Instruments Inc Pentapetides and a method of preparing them
US4028319A (en) * 1976-05-07 1977-06-07 G. D. Searle & Co. 2 and 3-substituted enkephalins
DK326477A (da) * 1976-07-27 1978-01-28 Reckitt & Colmann Prod Ltd Kemiske forbindelser og fremgangsmade til fremstilling af samme
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
US4259234A (en) * 1976-09-27 1981-03-31 Eli Lilly And Company Analgesic compounds

Also Published As

Publication number Publication date
GB2005688A (en) 1979-04-25
GR71651B (es) 1983-06-20
FR2404629B1 (fr) 1985-12-27
US4264491A (en) 1981-04-28
EP0001684A3 (en) 1979-06-27
CH635571A5 (fr) 1983-04-15
YU231578A (en) 1982-10-31
IT1100839B (it) 1985-09-28
PL114271B1 (en) 1981-01-31
IE781926L (en) 1979-04-03
BG31224A3 (en) 1981-11-16
FR2404629A1 (fr) 1979-04-27
PH14660A (en) 1981-10-20
EP0001684A2 (en) 1979-05-02
GB2005688B (en) 1982-02-24
FI66842C (fi) 1984-12-10
ES473925A1 (es) 1980-01-16
DK434778A (da) 1979-04-04
IT7828359A0 (it) 1978-10-02
FI66842B (fi) 1984-08-31
EP0001684B1 (en) 1981-09-02
RO76176A (ro) 1981-11-04
AT367028B (de) 1982-05-25
DK149231B (da) 1986-03-24
PT68598A (en) 1978-10-01
NZ188521A (en) 1981-07-13
IE47378B1 (en) 1984-03-07
IL55650A (en) 1982-02-28
CA1156219A (en) 1983-11-01
BE870819A (fr) 1979-03-28
SU908246A3 (ru) 1982-02-23
AU4024778A (en) 1980-04-03
AU520315B2 (en) 1982-01-28
DD139710A5 (de) 1980-01-16
DE2861019D1 (en) 1981-11-26
EG13636A (en) 1982-03-31
ATA708778A (de) 1981-10-15
JPS5459247A (en) 1979-05-12
CS235072B2 (en) 1985-04-16
ZA785564B (en) 1980-05-28
FI782971A (fi) 1979-04-04
PL210045A1 (pl) 1979-06-18
HU182866B (en) 1984-03-28
AR224238A1 (es) 1981-11-13
LU80316A1 (fr) 1979-03-16

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