DK1487431T3 - Forebyggelse og/eller behandling af cardiovaskulær sygdom og/eller dermed associeret hjertefejl - Google Patents
Forebyggelse og/eller behandling af cardiovaskulær sygdom og/eller dermed associeret hjertefejlInfo
- Publication number
- DK1487431T3 DK1487431T3 DK03744567.3T DK03744567T DK1487431T3 DK 1487431 T3 DK1487431 T3 DK 1487431T3 DK 03744567 T DK03744567 T DK 03744567T DK 1487431 T3 DK1487431 T3 DK 1487431T3
- Authority
- DK
- Denmark
- Prior art keywords
- patient
- prevention
- treatment
- heart failure
- cardiovascular disease
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 206010019280 Heart failures Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000017423 tissue regeneration Effects 0.000 abstract 2
- 230000002792 vascular Effects 0.000 abstract 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 210000004165 myocardium Anatomy 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/30—Copper compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Toxicology (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ51772102 | 2002-03-08 | ||
| NZ51772502 | 2002-03-11 | ||
| US36438202P | 2002-03-12 | 2002-03-12 | |
| PCT/NZ2003/000042 WO2003077901A1 (en) | 2002-03-08 | 2003-03-10 | Preventing and/or treating cardiovascular disease and/or associated heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1487431T3 true DK1487431T3 (da) | 2012-08-20 |
Family
ID=28046135
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03744567.3T DK1487431T3 (da) | 2002-03-08 | 2003-03-10 | Forebyggelse og/eller behandling af cardiovaskulær sygdom og/eller dermed associeret hjertefejl |
| DK11187394.9T DK2500018T3 (en) | 2002-03-08 | 2003-03-10 | Prevention and / or treatment of cardiovascular disease and / or associated heart failure |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11187394.9T DK2500018T3 (en) | 2002-03-08 | 2003-03-10 | Prevention and / or treatment of cardiovascular disease and / or associated heart failure |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US6951890B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP2500018B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP4860906B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN1649577A (cg-RX-API-DMAC10.html) |
| AT (1) | ATE555782T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2003225442B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2478997C (cg-RX-API-DMAC10.html) |
| DK (2) | DK1487431T3 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2386782T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2003077901A1 (cg-RX-API-DMAC10.html) |
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|---|---|---|---|---|
| WO2000018392A1 (en) | 1998-09-25 | 2000-04-06 | Glycox Corporation Limited | Fructosamine oxidase: antagonists and inhibitors |
| EP1471931A4 (en) * | 2001-08-24 | 2006-06-14 | Maine Medical Ct Res Inst | NON-TRADITIONAL EXPORT OF COPPER-DEPENDENT PRO-INFLAMMATORY CYTOKINES AND METHODS, COMPOSITIONS, AND KITS THEREOF |
| US20040038861A1 (en) * | 2001-11-26 | 2004-02-26 | Cooper Garth J. S. | Methods and compositions for normalizing lipid levels in mammalian tissues |
| EP2500018B1 (en) | 2002-03-08 | 2017-07-19 | PhilERA New Zealand Limited | Preventing and/or Treating Cardiovascular Disease and/or Associated Heart Failure |
| US6855340B2 (en) * | 2002-05-24 | 2005-02-15 | Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
| US20070248689A1 (en) * | 2002-05-24 | 2007-10-25 | Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
| US20040142393A1 (en) * | 2002-08-01 | 2004-07-22 | Cooper Garth James Smith | Methods of use of compounds with preptin function |
| US7977049B2 (en) | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| US20060100278A1 (en) * | 2002-08-20 | 2006-05-11 | Cooper Garth J S | Dosage forms and related therapies |
| US20050096256A1 (en) | 2003-07-01 | 2005-05-05 | President And Fellows Of Harvard College | Compositions for manipulating the lifespan and stress response of cells and organisms |
| CA2550505A1 (en) * | 2003-12-19 | 2005-06-30 | Protemix Corporation Limited | Copper antagonist compounds |
| US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| EP1708689A2 (en) | 2003-12-29 | 2006-10-11 | The President and Fellows of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
| US7563460B2 (en) * | 2004-02-26 | 2009-07-21 | Med Five, Inc. | Enteric coated oral pharmaceutical to erode kidney stones |
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| EP1778618B1 (en) | 2004-07-19 | 2013-12-25 | PhilERA New Zealand Limited | Synthesis of triethylenetetramines |
| HU227588B1 (hu) * | 2004-12-03 | 2011-09-28 | Sinnex Mueszaki Fejlesztoe Es Tanacsado Kft | Többszörösen telítetlen zsírsavak észtereit tartalmazó vírusellenes és immunstimuláns gyógyászati készítmény |
| WO2006104402A1 (en) * | 2005-03-26 | 2006-10-05 | Protemix Corporation Limited | Copper antagonist compositions |
| WO2006104398A1 (en) * | 2005-03-26 | 2006-10-05 | Protemix Corporation Limited | Copper antagonist compositions |
| EP1874285B1 (en) * | 2005-04-07 | 2009-10-07 | Astrum Therapeutics Pty, Ltd. | Complementary compositions to reduce blood glucose levels and treat diabetes |
| AU2006240568A1 (en) * | 2005-04-25 | 2006-11-02 | Philera New Zealand Limited | Copper regulation evaluation and therapy |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| EP1948160A4 (en) * | 2005-11-09 | 2013-07-10 | Protemix Corp Ltd | TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS |
| JP2009523175A (ja) * | 2006-01-10 | 2009-06-18 | パイペックス,インコーポレイテッド | 目標とされる安定な銅状態を達成及び維持して銅関連中枢神経系疾患を予防及び治療するための医薬組成物及び方法 |
| KR100821649B1 (ko) | 2006-01-24 | 2008-04-11 | 서울시립대학교 산학협력단 | 클리오퀴놀을 유효성분으로 포함하는 HIF-1α 활성제 |
| CN101437503A (zh) * | 2006-02-21 | 2009-05-20 | 阿斯特鲁姆医疗有限公司 | 用于降低血糖水平和治疗糖尿病的组合物 |
| WO2007116243A2 (en) * | 2006-04-10 | 2007-10-18 | Mintails Limited | Method for treating fibromyalgia and related conditions |
| US20090270420A1 (en) * | 2006-06-01 | 2009-10-29 | Sobel Burton E | Methods for inhibiting cardiac pai-1 |
| KR100816798B1 (ko) * | 2006-09-08 | 2008-03-25 | (주)팜스웰 | 의약용 트리에틸렌테트라민 이염산염의 제조방법 |
| CN101702884A (zh) * | 2007-03-09 | 2010-05-05 | 西姆科皮亚公司 | 用于治疗高血糖症及相关病症的脂肪酸氧化抑制剂 |
| US20100311092A1 (en) * | 2007-11-30 | 2010-12-09 | Kurland Irwin J | Metabolic fuel switching biomarker |
| WO2010020959A1 (en) * | 2008-08-21 | 2010-02-25 | University Of Cape Town | Resveratrol-containing composition for treating heart failure |
| US20100234906A1 (en) * | 2009-03-16 | 2010-09-16 | Pacesetter, Inc. | System and method for controlling rate-adaptive pacing based on a cardiac force-frequency relation detected by an implantable medical device |
| JP5896375B2 (ja) | 2011-09-09 | 2016-03-30 | 池田食研株式会社 | 改変型グルコース脱水素酵素遺伝子 |
| WO2014145705A2 (en) | 2013-03-15 | 2014-09-18 | Battelle Memorial Institute | Progression analytics system |
| WO2014152207A1 (en) | 2013-03-15 | 2014-09-25 | Mylan Laboratories, Inc. | Hot melt granulation formulations of poorly water-soluble active agents |
| CZ307108B6 (cs) * | 2013-09-06 | 2018-01-17 | Vysoké Učení Technické V Brně | Multifunkční poloprovozní jednotka pro snižování polutantů z odpadního plynu |
| EP2845640B1 (en) | 2013-09-06 | 2018-10-24 | Vysoké Ucení Technické V Brne | Multifunction operation unit for reducing pollutant concentration in a waste gas |
| JP2018505407A (ja) | 2015-01-07 | 2018-02-22 | ノッティンガム ユニバーシティ ホスピタルズ エヌエイチエス トラストNottingham University Hospitals Nhs Trust | 検査方法、原子種の使用方法、検査装置、及び、テストキット |
| WO2017049529A1 (en) * | 2015-09-24 | 2017-03-30 | Innolife Co., Ltd. | A pharmaceutical composition comprising a copper chelating tetramine and the use thereof |
| WO2018005990A2 (en) * | 2016-07-01 | 2018-01-04 | Marshall University Research Corporation | Compositions and methods for treating uremic cardiomyopathy |
| CN107811997A (zh) * | 2017-11-10 | 2018-03-20 | 大连医科大学附属第医院 | 蛋白酶体抑制剂白藜芦醇在预防和治疗心血管疾病中的应用 |
| TWI902661B (zh) | 2018-05-04 | 2025-11-01 | 法商奧法蘭股份公司 | 三伸乙基四胺四鹽酸鹽之結晶型及其醫藥用途 |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| EP3947433A4 (en) * | 2019-04-02 | 2022-11-23 | The Regents of The University of Michigan | USE OF SOLUBLE UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR LEVELS IN THE MANAGEMENT OF PATIENTS WITH CARDIOVASCULAR DISEASES |
| CN114867474A (zh) * | 2019-06-17 | 2022-08-05 | 菲勒拉新西兰有限责任公司 | 中枢神经系统病症的联合治疗 |
| CN112138024A (zh) | 2019-06-26 | 2020-12-29 | 里弗斯Pah有限责任公司 | 治疗严重形式的肺动脉高压的方法 |
| CN110464717B (zh) * | 2019-09-23 | 2022-02-18 | 张建国 | 一种2,4-二羟基苯甲酸在制备降低血糖的药物的应用 |
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| CN115998955B (zh) * | 2022-12-09 | 2024-12-20 | 首都医科大学附属北京安贞医院 | 一种静脉桥的醛铬复合交联方法 |
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-
2003
- 2003-03-10 EP EP11187394.9A patent/EP2500018B1/en not_active Expired - Lifetime
- 2003-03-10 DK DK03744567.3T patent/DK1487431T3/da active
- 2003-03-10 JP JP2003575954A patent/JP4860906B2/ja not_active Expired - Fee Related
- 2003-03-10 WO PCT/NZ2003/000042 patent/WO2003077901A1/en not_active Ceased
- 2003-03-10 AU AU2003225442A patent/AU2003225442B2/en not_active Ceased
- 2003-03-10 CA CA2478997A patent/CA2478997C/en not_active Expired - Fee Related
- 2003-03-10 ES ES03744567T patent/ES2386782T3/es not_active Expired - Lifetime
- 2003-03-10 CN CNA038101513A patent/CN1649577A/zh active Pending
- 2003-03-10 DK DK11187394.9T patent/DK2500018T3/en active
- 2003-03-10 EP EP03744567A patent/EP1487431B1/en not_active Expired - Lifetime
- 2003-03-10 AT AT03744567T patent/ATE555782T1/de active
- 2003-03-12 US US10/388,213 patent/US6951890B2/en not_active Expired - Lifetime
-
2005
- 2005-09-07 US US11/221,298 patent/US8034799B2/en not_active Expired - Fee Related
-
2011
- 2011-02-28 US US13/037,223 patent/US8563538B2/en not_active Expired - Fee Related
-
2013
- 2013-09-18 US US14/029,984 patent/US8987244B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003225442A1 (en) | 2003-09-29 |
| US20110212188A1 (en) | 2011-09-01 |
| US8563538B2 (en) | 2013-10-22 |
| JP2005533003A (ja) | 2005-11-04 |
| CA2478997C (en) | 2013-12-17 |
| CA2478997A1 (en) | 2003-09-25 |
| EP2500018A1 (en) | 2012-09-19 |
| US20060009534A1 (en) | 2006-01-12 |
| US20140113969A1 (en) | 2014-04-24 |
| AU2003225442B2 (en) | 2010-02-04 |
| US8987244B2 (en) | 2015-03-24 |
| WO2003077901A1 (en) | 2003-09-25 |
| US6951890B2 (en) | 2005-10-04 |
| US20030203973A1 (en) | 2003-10-30 |
| EP2500018B1 (en) | 2017-07-19 |
| DK2500018T3 (en) | 2017-10-02 |
| JP4860906B2 (ja) | 2012-01-25 |
| EP1487431A4 (en) | 2006-10-25 |
| HK1071313A1 (en) | 2005-07-15 |
| EP1487431B1 (en) | 2012-05-02 |
| CN1649577A (zh) | 2005-08-03 |
| US8034799B2 (en) | 2011-10-11 |
| ES2386782T3 (es) | 2012-08-30 |
| EP1487431A1 (en) | 2004-12-22 |
| ATE555782T1 (de) | 2012-05-15 |
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