NO951066L - Transkutan in vivo aktivering av fotosensitive midler i blod - Google Patents
Transkutan in vivo aktivering av fotosensitive midler i blodInfo
- Publication number
- NO951066L NO951066L NO951066A NO951066A NO951066L NO 951066 L NO951066 L NO 951066L NO 951066 A NO951066 A NO 951066A NO 951066 A NO951066 A NO 951066A NO 951066 L NO951066 L NO 951066L
- Authority
- NO
- Norway
- Prior art keywords
- target cells
- cells
- transcutaneous
- blood
- vivo activation
- Prior art date
Links
- 230000004913 activation Effects 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 2
- 244000045947 parasite Species 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000003504 photosensitizing agent Substances 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Det beskrives en fremgangsmåte hvor målceller som selektivt har akkumulert et fotosensibiliserende middel, ødelegges eller skades. Målcellene befinner seg i. blodstrømmen til et intakt dyr, hvor blodstrømmen og dyret også inneholder ikke-målceller. Bestråling påføres transkutant til i det minste en del av det intakte dyr med en intensitet som effektivt skader eller ødelegger målcellene selektivt og etterlater ikke-målceller relativt uskadet. Målceller inkluderer leukemiceller, virus-holdige celler, parasitt- holdige celler og mikroorganismer som bakterier, parasitter og frie virus.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94811392A | 1992-09-21 | 1992-09-21 | |
PCT/CA1993/000382 WO1994006424A1 (en) | 1992-09-21 | 1993-09-20 | Transcutaneous in vivo activation of photosensitive agents in blood |
Publications (2)
Publication Number | Publication Date |
---|---|
NO951066D0 NO951066D0 (no) | 1995-03-20 |
NO951066L true NO951066L (no) | 1995-05-19 |
Family
ID=25487290
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO951066A NO951066L (no) | 1992-09-21 | 1995-03-20 | Transkutan in vivo aktivering av fotosensitive midler i blod |
Country Status (21)
Country | Link |
---|---|
US (2) | US5484803A (no) |
EP (1) | EP0660712B1 (no) |
JP (2) | JP3598306B2 (no) |
AT (1) | ATE201596T1 (no) |
AU (1) | AU681088B2 (no) |
CA (1) | CA2144327C (no) |
DE (1) | DE69330277T2 (no) |
DK (1) | DK0660712T3 (no) |
ES (1) | ES2160600T3 (no) |
FI (1) | FI951295A (no) |
GR (1) | GR3036479T3 (no) |
HU (1) | HU220251B (no) |
IL (1) | IL107035A (no) |
NO (1) | NO951066L (no) |
NZ (1) | NZ255302A (no) |
PL (1) | PL308116A1 (no) |
PT (1) | PT660712E (no) |
SK (1) | SK35295A3 (no) |
TW (1) | TW241204B (no) |
WO (1) | WO1994006424A1 (no) |
ZA (1) | ZA936968B (no) |
Families Citing this family (51)
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---|---|---|---|---|
US6710066B2 (en) * | 1989-07-28 | 2004-03-23 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
US5955490A (en) * | 1989-07-28 | 1999-09-21 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
US20020058008A1 (en) * | 1989-07-28 | 2002-05-16 | Kennedy James C. | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
US5798238A (en) * | 1990-04-16 | 1998-08-25 | Baxter International Inc. | Method of inactivation of viral and bacterial blood contaminants with quinolines as photosensitizer |
US5587490A (en) * | 1990-04-16 | 1996-12-24 | Credit Managers Association Of California | Method of inactivation of viral and bacterial blood contaminants |
US20040110819A1 (en) * | 1991-10-28 | 2004-06-10 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
PT680365E (pt) * | 1992-11-20 | 2000-07-31 | Univ British Columbia | Activacao de agentes fotossensibilizadores |
WO1996039188A1 (en) * | 1995-06-05 | 1996-12-12 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
US6008211A (en) * | 1995-07-27 | 1999-12-28 | Pdt Pharmaceuticals, Inc. | Photoactivatable compounds comprising benzochlorin and furocoumarin |
JP2000500137A (ja) * | 1995-11-06 | 2000-01-11 | ニューヨーク・ブラッド・センター・インコーポレイテッド | フタロシアニン及び赤色光を用いた赤血球細胞のウイルス不活性化処理 |
US5895786A (en) * | 1996-05-08 | 1999-04-20 | New York Blood Center, Inc. | Method for treating viral infections |
US6159733A (en) * | 1996-06-20 | 2000-12-12 | New York Blood Center, Inc. | Method for photoinactivating malignant cells |
US5922278A (en) † | 1996-11-19 | 1999-07-13 | Baxter International Inc. | Method and apparatus for inactivating contaminants in biological fluid |
US5742380A (en) * | 1996-12-31 | 1998-04-21 | Ronn Avigdor M | Plasma assay spectrometer |
US6103706A (en) * | 1997-04-29 | 2000-08-15 | New York Blood Center, Inc. | Methods for treating viral infections |
US6010890A (en) * | 1997-04-29 | 2000-01-04 | New York Blood Center, Inc. | Method for viral inactivation and compositions for use in same |
US5856566A (en) | 1997-09-02 | 1999-01-05 | Dusa Pharmaceuticals, Inc. | Sterilized 5-aminolevulinic acid |
US6159178A (en) | 1998-01-23 | 2000-12-12 | Heartport, Inc. | Methods and devices for occluding the ascending aorta and maintaining circulation of oxygenated blood in the patient when the patient's heart is arrested |
US6096066A (en) * | 1998-09-11 | 2000-08-01 | Light Sciences Limited Partnership | Conformal patch for administering light therapy to subcutaneous tumors |
US6183773B1 (en) | 1999-01-04 | 2001-02-06 | The General Hospital Corporation | Targeting of sebaceous follicles as a treatment of sebaceous gland disorders |
ATE234114T1 (de) * | 1999-01-15 | 2003-03-15 | Light Sciences Corp | Therapeutische zusammensetzungen fur knochenstoffwechselstörungen oder knochenmetastasen enthaltend einen photosensitizer und ein bisphosphonat |
US6602274B1 (en) * | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
US6454789B1 (en) * | 1999-01-15 | 2002-09-24 | Light Science Corporation | Patient portable device for photodynamic therapy |
AU2412800A (en) * | 1999-01-15 | 2000-08-01 | Light Sciences Corporation | Noninvasive vascular therapy |
US6376483B1 (en) | 1999-05-27 | 2002-04-23 | Miravant Pharmaceuticals, Inc. | Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production |
US20030114434A1 (en) * | 1999-08-31 | 2003-06-19 | James Chen | Extended duration light activated cancer therapy |
DE19960705A1 (de) * | 1999-12-16 | 2001-06-21 | Laser & Med Tech Gmbh | Verfahren und Vorrichtung zur Herstellung eines autologen Immunisierungsimpfstoffes gegen Krebserkrankungen (Tumorvakzine) |
US7897140B2 (en) | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
EP1267935A2 (en) * | 2000-01-12 | 2003-01-02 | Light Sciences Corporation | Novel treatment for eye disease |
KR100365151B1 (ko) * | 2000-05-08 | 2003-02-11 | 김형락 | 어류 병원성 세균과 바이러스의 감염 예방 및 치료를 위한δ-아미노레불린산의 신규한 용도 |
DE10034673C1 (de) | 2000-07-17 | 2002-04-25 | Medac Klinische Spezialpraep | Dermales Applikationssystem für Aminolävulinsäure und seine Verwendung |
EP2248536A3 (en) | 2000-12-14 | 2010-12-08 | The General Hospital Corporation doing business as Massachusetts General Hospital | Topical Aminolevulinic acid-photodynamic therapy for acne vulgaris |
WO2002013788A1 (en) | 2000-08-16 | 2002-02-21 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Topical aminolevulinic acid-photodynamic therapy for acne vulgaris |
CA2445898A1 (en) * | 2001-05-01 | 2002-12-19 | The General Hospital Corporation | Photoimmunotherapies for cancer using photosensitizer immunoconjugates and combination therapies |
US20030103995A1 (en) * | 2001-06-04 | 2003-06-05 | Hamblin Michael R. | Detection and therapy of vulnerable plaque with photodynamic compounds |
DE10162712A1 (de) * | 2001-12-19 | 2003-07-17 | Blutspendienst Der Landesverba | Verfahren zur Inaktivierung von Bakterien und Leukozyten in Blut oder Blutprodukten |
JP2005527493A (ja) * | 2002-01-23 | 2005-09-15 | ライト サイエンシーズ コーポレイション | 光線力学療法のためのシステムおよび方法 |
EP1517684B1 (en) | 2002-06-27 | 2009-07-22 | Health Research, Inc. | Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy |
AU2003249742A1 (en) | 2002-07-02 | 2004-01-23 | Health Research, Inc. | Efficient synthesis of pyropheophorbide a and its derivatives |
US7220778B2 (en) * | 2003-04-15 | 2007-05-22 | The General Hospital Corporation | Methods and devices for epithelial protection during photodynamic therapy |
US7659301B2 (en) * | 2003-04-15 | 2010-02-09 | The General Hospital Corporation | Methods and devices for epithelial protection during photodynamic therapy |
WO2004099375A2 (en) * | 2003-04-30 | 2004-11-18 | The General Hospital Corporation | Indirectly linked photosensitizer immunoconjugates, processes for the production thereof and methods of use therof |
JP2007500227A (ja) * | 2003-05-29 | 2007-01-11 | ミトス・ファーマシューティカルズ・インコーポレーテッド | 光増感剤及び音増感剤と関連してのニトロキシドの使用方法 |
FR2857264A1 (fr) * | 2003-07-09 | 2005-01-14 | Maco Pharma Sa | Procede d'inactivation photodynamique des pathogenes au moyen d'ala |
GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
US8585707B2 (en) | 2006-06-07 | 2013-11-19 | Gary S. Rogers | Continuous low irradiance photodynamic therapy method |
US20080164224A1 (en) * | 2007-01-04 | 2008-07-10 | Whirlpool Corporation | System for connecting mechnically dissimilar consumer electronic devices to an adaptor or a host |
CA2724949A1 (en) | 2007-06-27 | 2008-12-31 | The General Hospital Corporation | Method and apparatus for optical inhibition of photodynamic therapy |
US20090062724A1 (en) * | 2007-08-31 | 2009-03-05 | Rixen Chen | System and apparatus for sonodynamic therapy |
US8835104B2 (en) * | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
WO2012139017A1 (en) | 2011-04-07 | 2012-10-11 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4649151A (en) * | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
US5095030A (en) * | 1987-01-20 | 1992-03-10 | University Of British Columbia | Wavelength-specific cytotoxic agents |
US4961920A (en) * | 1988-12-08 | 1990-10-09 | Luminis Pty, Ltd. | Phototherapeutic monovinyl and divinyl ether-linked dimers |
US4960408A (en) * | 1989-01-10 | 1990-10-02 | Klainer Albert S | Treatment methods and vaccines for stimulating an immunological response against retroviruses |
-
1993
- 1993-09-20 ES ES93918860T patent/ES2160600T3/es not_active Expired - Lifetime
- 1993-09-20 HU HU9500814A patent/HU220251B/hu not_active IP Right Cessation
- 1993-09-20 NZ NZ255302A patent/NZ255302A/en unknown
- 1993-09-20 WO PCT/CA1993/000382 patent/WO1994006424A1/en active IP Right Grant
- 1993-09-20 PL PL93308116A patent/PL308116A1/xx unknown
- 1993-09-20 AT AT93918860T patent/ATE201596T1/de not_active IP Right Cessation
- 1993-09-20 SK SK352-95A patent/SK35295A3/sk unknown
- 1993-09-20 IL IL10703593A patent/IL107035A/en not_active IP Right Cessation
- 1993-09-20 CA CA002144327A patent/CA2144327C/en not_active Expired - Fee Related
- 1993-09-20 AU AU49405/93A patent/AU681088B2/en not_active Ceased
- 1993-09-20 PT PT93918860T patent/PT660712E/pt unknown
- 1993-09-20 JP JP50762994A patent/JP3598306B2/ja not_active Expired - Fee Related
- 1993-09-20 EP EP93918860A patent/EP0660712B1/en not_active Expired - Lifetime
- 1993-09-20 DE DE69330277T patent/DE69330277T2/de not_active Expired - Fee Related
- 1993-09-20 DK DK93918860T patent/DK0660712T3/da active
- 1993-09-21 ZA ZA936968A patent/ZA936968B/xx unknown
- 1993-10-05 TW TW082108212A patent/TW241204B/zh active
-
1995
- 1995-02-02 US US08/384,440 patent/US5484803A/en not_active Expired - Lifetime
- 1995-03-20 NO NO951066A patent/NO951066L/no not_active Application Discontinuation
- 1995-03-20 FI FI951295A patent/FI951295A/fi unknown
- 1995-11-08 US US08/555,235 patent/US5736563A/en not_active Expired - Fee Related
-
2001
- 2001-04-04 JP JP2001105544A patent/JP2001316288A/ja active Pending
- 2001-08-30 GR GR20010401338T patent/GR3036479T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO951066D0 (no) | 1995-03-20 |
HU220251B (hu) | 2001-11-28 |
NZ255302A (en) | 2001-04-27 |
PT660712E (pt) | 2001-11-30 |
EP0660712B1 (en) | 2001-05-30 |
IL107035A0 (en) | 1993-12-28 |
HUT70966A (en) | 1995-11-28 |
GR3036479T3 (en) | 2001-11-30 |
CA2144327C (en) | 2002-08-06 |
ZA936968B (en) | 1994-04-12 |
IL107035A (en) | 1998-12-27 |
FI951295A0 (fi) | 1995-03-20 |
JP3598306B2 (ja) | 2004-12-08 |
DE69330277T2 (de) | 2002-04-18 |
US5484803A (en) | 1996-01-16 |
ES2160600T3 (es) | 2001-11-16 |
JP2001316288A (ja) | 2001-11-13 |
AU4940593A (en) | 1994-04-12 |
US5736563A (en) | 1998-04-07 |
DE69330277D1 (de) | 2001-07-05 |
SK35295A3 (en) | 1996-05-08 |
CA2144327A1 (en) | 1994-03-31 |
AU681088B2 (en) | 1997-08-21 |
ATE201596T1 (de) | 2001-06-15 |
FI951295A (fi) | 1995-05-17 |
DK0660712T3 (da) | 2001-08-27 |
JPH08501301A (ja) | 1996-02-13 |
PL308116A1 (en) | 1995-07-24 |
WO1994006424A1 (en) | 1994-03-31 |
TW241204B (no) | 1995-02-21 |
EP0660712A1 (en) | 1995-07-05 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |