NO951066L - Transkutan in vivo aktivering av fotosensitive midler i blod - Google Patents

Transkutan in vivo aktivering av fotosensitive midler i blod

Info

Publication number
NO951066L
NO951066L NO951066A NO951066A NO951066L NO 951066 L NO951066 L NO 951066L NO 951066 A NO951066 A NO 951066A NO 951066 A NO951066 A NO 951066A NO 951066 L NO951066 L NO 951066L
Authority
NO
Norway
Prior art keywords
target cells
cells
transcutaneous
blood
vivo activation
Prior art date
Application number
NO951066A
Other languages
English (en)
Other versions
NO951066D0 (no
Inventor
Anna M Richter
Original Assignee
Quadra Logic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadra Logic Tech Inc filed Critical Quadra Logic Tech Inc
Publication of NO951066D0 publication Critical patent/NO951066D0/no
Publication of NO951066L publication Critical patent/NO951066L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Det beskrives en fremgangsmåte hvor målceller som selektivt har akkumulert et fotosensibiliserende middel, ødelegges eller skades. Målcellene befinner seg i. blodstrømmen til et intakt dyr, hvor blodstrømmen og dyret også inneholder ikke-målceller. Bestråling påføres transkutant til i det minste en del av det intakte dyr med en intensitet som effektivt skader eller ødelegger målcellene selektivt og etterlater ikke-målceller relativt uskadet. Målceller inkluderer leukemiceller, virus-holdige celler, parasitt- holdige celler og mikroorganismer som bakterier, parasitter og frie virus.
NO951066A 1992-09-21 1995-03-20 Transkutan in vivo aktivering av fotosensitive midler i blod NO951066L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94811392A 1992-09-21 1992-09-21
PCT/CA1993/000382 WO1994006424A1 (en) 1992-09-21 1993-09-20 Transcutaneous in vivo activation of photosensitive agents in blood

Publications (2)

Publication Number Publication Date
NO951066D0 NO951066D0 (no) 1995-03-20
NO951066L true NO951066L (no) 1995-05-19

Family

ID=25487290

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951066A NO951066L (no) 1992-09-21 1995-03-20 Transkutan in vivo aktivering av fotosensitive midler i blod

Country Status (21)

Country Link
US (2) US5484803A (no)
EP (1) EP0660712B1 (no)
JP (2) JP3598306B2 (no)
AT (1) ATE201596T1 (no)
AU (1) AU681088B2 (no)
CA (1) CA2144327C (no)
DE (1) DE69330277T2 (no)
DK (1) DK0660712T3 (no)
ES (1) ES2160600T3 (no)
FI (1) FI951295A (no)
GR (1) GR3036479T3 (no)
HU (1) HU220251B (no)
IL (1) IL107035A (no)
NO (1) NO951066L (no)
NZ (1) NZ255302A (no)
PL (1) PL308116A1 (no)
PT (1) PT660712E (no)
SK (1) SK35295A3 (no)
TW (1) TW241204B (no)
WO (1) WO1994006424A1 (no)
ZA (1) ZA936968B (no)

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US5798238A (en) * 1990-04-16 1998-08-25 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants with quinolines as photosensitizer
US5587490A (en) * 1990-04-16 1996-12-24 Credit Managers Association Of California Method of inactivation of viral and bacterial blood contaminants
US20040110819A1 (en) * 1991-10-28 2004-06-10 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
PT680365E (pt) * 1992-11-20 2000-07-31 Univ British Columbia Activacao de agentes fotossensibilizadores
WO1996039188A1 (en) * 1995-06-05 1996-12-12 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US6008211A (en) * 1995-07-27 1999-12-28 Pdt Pharmaceuticals, Inc. Photoactivatable compounds comprising benzochlorin and furocoumarin
JP2000500137A (ja) * 1995-11-06 2000-01-11 ニューヨーク・ブラッド・センター・インコーポレイテッド フタロシアニン及び赤色光を用いた赤血球細胞のウイルス不活性化処理
US5895786A (en) * 1996-05-08 1999-04-20 New York Blood Center, Inc. Method for treating viral infections
US6159733A (en) * 1996-06-20 2000-12-12 New York Blood Center, Inc. Method for photoinactivating malignant cells
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US6010890A (en) * 1997-04-29 2000-01-04 New York Blood Center, Inc. Method for viral inactivation and compositions for use in same
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US6159178A (en) 1998-01-23 2000-12-12 Heartport, Inc. Methods and devices for occluding the ascending aorta and maintaining circulation of oxygenated blood in the patient when the patient's heart is arrested
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US6183773B1 (en) 1999-01-04 2001-02-06 The General Hospital Corporation Targeting of sebaceous follicles as a treatment of sebaceous gland disorders
ATE234114T1 (de) * 1999-01-15 2003-03-15 Light Sciences Corp Therapeutische zusammensetzungen fur knochenstoffwechselstörungen oder knochenmetastasen enthaltend einen photosensitizer und ein bisphosphonat
US6602274B1 (en) * 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
US6454789B1 (en) * 1999-01-15 2002-09-24 Light Science Corporation Patient portable device for photodynamic therapy
AU2412800A (en) * 1999-01-15 2000-08-01 Light Sciences Corporation Noninvasive vascular therapy
US6376483B1 (en) 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production
US20030114434A1 (en) * 1999-08-31 2003-06-19 James Chen Extended duration light activated cancer therapy
DE19960705A1 (de) * 1999-12-16 2001-06-21 Laser & Med Tech Gmbh Verfahren und Vorrichtung zur Herstellung eines autologen Immunisierungsimpfstoffes gegen Krebserkrankungen (Tumorvakzine)
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1267935A2 (en) * 2000-01-12 2003-01-02 Light Sciences Corporation Novel treatment for eye disease
KR100365151B1 (ko) * 2000-05-08 2003-02-11 김형락 어류 병원성 세균과 바이러스의 감염 예방 및 치료를 위한δ-아미노레불린산의 신규한 용도
DE10034673C1 (de) 2000-07-17 2002-04-25 Medac Klinische Spezialpraep Dermales Applikationssystem für Aminolävulinsäure und seine Verwendung
EP2248536A3 (en) 2000-12-14 2010-12-08 The General Hospital Corporation doing business as Massachusetts General Hospital Topical Aminolevulinic acid-photodynamic therapy for acne vulgaris
WO2002013788A1 (en) 2000-08-16 2002-02-21 The General Hospital Corporation D/B/A Massachusetts General Hospital Topical aminolevulinic acid-photodynamic therapy for acne vulgaris
CA2445898A1 (en) * 2001-05-01 2002-12-19 The General Hospital Corporation Photoimmunotherapies for cancer using photosensitizer immunoconjugates and combination therapies
US20030103995A1 (en) * 2001-06-04 2003-06-05 Hamblin Michael R. Detection and therapy of vulnerable plaque with photodynamic compounds
DE10162712A1 (de) * 2001-12-19 2003-07-17 Blutspendienst Der Landesverba Verfahren zur Inaktivierung von Bakterien und Leukozyten in Blut oder Blutprodukten
JP2005527493A (ja) * 2002-01-23 2005-09-15 ライト サイエンシーズ コーポレイション 光線力学療法のためのシステムおよび方法
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Also Published As

Publication number Publication date
NO951066D0 (no) 1995-03-20
HU220251B (hu) 2001-11-28
NZ255302A (en) 2001-04-27
PT660712E (pt) 2001-11-30
EP0660712B1 (en) 2001-05-30
IL107035A0 (en) 1993-12-28
HUT70966A (en) 1995-11-28
GR3036479T3 (en) 2001-11-30
CA2144327C (en) 2002-08-06
ZA936968B (en) 1994-04-12
IL107035A (en) 1998-12-27
FI951295A0 (fi) 1995-03-20
JP3598306B2 (ja) 2004-12-08
DE69330277T2 (de) 2002-04-18
US5484803A (en) 1996-01-16
ES2160600T3 (es) 2001-11-16
JP2001316288A (ja) 2001-11-13
AU4940593A (en) 1994-04-12
US5736563A (en) 1998-04-07
DE69330277D1 (de) 2001-07-05
SK35295A3 (en) 1996-05-08
CA2144327A1 (en) 1994-03-31
AU681088B2 (en) 1997-08-21
ATE201596T1 (de) 2001-06-15
FI951295A (fi) 1995-05-17
DK0660712T3 (da) 2001-08-27
JPH08501301A (ja) 1996-02-13
PL308116A1 (en) 1995-07-24
WO1994006424A1 (en) 1994-03-31
TW241204B (no) 1995-02-21
EP0660712A1 (en) 1995-07-05

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