ATE78397T1 - Verwendung von p-chlorophenoxyazetat von n,ndimethylbiguanidzur behandlung von neuropathien und nervendegeneration. - Google Patents
Verwendung von p-chlorophenoxyazetat von n,ndimethylbiguanidzur behandlung von neuropathien und nervendegeneration.Info
- Publication number
- ATE78397T1 ATE78397T1 AT86401717T AT86401717T ATE78397T1 AT E78397 T1 ATE78397 T1 AT E78397T1 AT 86401717 T AT86401717 T AT 86401717T AT 86401717 T AT86401717 T AT 86401717T AT E78397 T1 ATE78397 T1 AT E78397T1
- Authority
- AT
- Austria
- Prior art keywords
- ndimethylbiguanide
- chlorophenoxyacetate
- neuropathies
- treatment
- nerve degeneration
- Prior art date
Links
- SODPIMGUZLOIPE-UHFFFAOYSA-N (4-chlorophenoxy)acetic acid Chemical compound OC(=O)COC1=CC=C(Cl)C=C1 SODPIMGUZLOIPE-UHFFFAOYSA-N 0.000 title abstract 2
- 230000007823 neuropathy Effects 0.000 title abstract 2
- 206010056677 Nerve degeneration Diseases 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical class CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000004126 nerve fiber Anatomy 0.000 abstract 1
- 201000001119 neuropathy Diseases 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8511664A FR2585572B3 (fr) | 1985-07-31 | 1985-07-31 | Nouvelles compositions pharmaceutiques a base d'un sel de l'acide p. chlorophenoxyacetique destinees au traitement des neuropathies et assurant la regeneration nerveuse |
| EP86401717A EP0214017B1 (de) | 1985-07-31 | 1986-07-31 | Verwendung von P-Chlorophenoxyazetat von N,N-Dimethylbiguanid zur Behandlung von Neuropathien und Nervendegeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE78397T1 true ATE78397T1 (de) | 1992-08-15 |
Family
ID=9321794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86401717T ATE78397T1 (de) | 1985-07-31 | 1986-07-31 | Verwendung von p-chlorophenoxyazetat von n,ndimethylbiguanidzur behandlung von neuropathien und nervendegeneration. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4835184A (de) |
| EP (1) | EP0214017B1 (de) |
| JP (1) | JPH0725671B2 (de) |
| AT (1) | ATE78397T1 (de) |
| AU (1) | AU587054B2 (de) |
| DE (1) | DE3686108T2 (de) |
| FR (1) | FR2585572B3 (de) |
| IE (1) | IE58000B1 (de) |
| ZA (1) | ZA865735B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100919A (en) * | 1984-03-19 | 1992-03-31 | The Rockefeller University | Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein |
| FR2687316B3 (fr) * | 1992-02-13 | 1994-08-12 | Rolland Sa A | Nouvelle utilisation de compositions pharmaceutiques a base de derives phenoxyacetiques en vue de la restauration des fonctions nerveuses. |
| FR2809310B1 (fr) | 2000-05-26 | 2004-02-13 | Centre Nat Rech Scient | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
| US8216609B2 (en) | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
| US8268352B2 (en) | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
| EP1948150A4 (de) * | 2005-11-07 | 2010-04-14 | Elixir Pharmaceuticals Inc | Kombinationen aus metformin und meglitinid |
| EP2109447B1 (de) * | 2007-01-29 | 2015-06-10 | HanAll Biopharma Co., Ltd. | N,n-dimethyl-imidodicarbonimid-diamid-acetat, verfahren zu seiner herstellung und pharmazeutische zusammensetzungen damit |
| EP2203418B1 (de) * | 2007-09-21 | 2017-10-25 | HanAll Biopharma Co., Ltd. | N,n-dimethyl-imidodicarbonimid-diamid-dicarboxylat, verfahren zu seiner herstellung und pharmazeutische zusammensetzungen damit |
| KR101104912B1 (ko) | 2008-01-08 | 2012-01-12 | 한올바이오파마주식회사 | Ｎ,ｎ―디메틸 이미도디카르본이미딕 디아미드의 니코틴산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물 |
| HRP20140194T1 (hr) | 2008-06-26 | 2014-06-20 | Laboratorios Silanes, S.A. De C.V. | Nova sol metformin glicinat za kontrolu glukoze u krvi |
| US20110021634A1 (en) | 2009-06-18 | 2011-01-27 | Patel Pranav Dushyant | Processes for preparing metformin hydrochloride |
| WO2011049400A2 (ko) * | 2009-10-23 | 2011-04-28 | 한올바이오파마주식회사 | N,n-디메틸 이미도디카르본이미딕 디아미드의 산 부가염을 포함하는 항암용 약제학적 조성물 |
| US11510886B2 (en) | 2016-09-30 | 2022-11-29 | Laboratorios Silanes, S.A. De C.V. | Metformin amino acid compounds and methods of using the same |
| US11185516B2 (en) | 2016-09-30 | 2021-11-30 | Laboratorios Silanes S.A. De C.V. | Metformin glycinate, pharmaceutical compositions comprising the same, and methods of using the same |
| EP3676297B1 (de) | 2017-09-01 | 2023-05-17 | Denali Therapeutics Inc. | Verbindungen, zusammensetzungen und verfahren |
| EP3924341A4 (de) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Verbindungen, zusammensetzungen und verfahren |
| JP2025523444A (ja) * | 2022-06-23 | 2025-07-23 | デナリ セラピューティクス インコーポレイテッド | 真核生物型開始因子２ｂのモジュレーターの調製プロセス |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR7116M (de) * | 1968-01-08 | 1969-07-15 |
-
1985
- 1985-07-31 FR FR8511664A patent/FR2585572B3/fr not_active Expired
-
1986
- 1986-07-30 IE IE2028/86A patent/IE58000B1/en not_active IP Right Cessation
- 1986-07-31 JP JP61181195A patent/JPH0725671B2/ja not_active Expired - Lifetime
- 1986-07-31 DE DE8686401717T patent/DE3686108T2/de not_active Expired - Fee Related
- 1986-07-31 EP EP86401717A patent/EP0214017B1/de not_active Expired - Lifetime
- 1986-07-31 ZA ZA865735A patent/ZA865735B/xx unknown
- 1986-07-31 AU AU60768/86A patent/AU587054B2/en not_active Ceased
- 1986-07-31 AT AT86401717T patent/ATE78397T1/de not_active IP Right Cessation
- 1986-08-01 US US06/893,025 patent/US4835184A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IE58000B1 (en) | 1993-06-02 |
| EP0214017A3 (en) | 1989-07-26 |
| EP0214017B1 (de) | 1992-07-22 |
| DE3686108T2 (de) | 1993-03-04 |
| JPH0725671B2 (ja) | 1995-03-22 |
| IE862028L (en) | 1987-01-31 |
| ZA865735B (en) | 1987-11-25 |
| FR2585572A1 (fr) | 1987-02-06 |
| AU587054B2 (en) | 1989-08-03 |
| AU6076886A (en) | 1987-02-05 |
| DE3686108D1 (de) | 1992-08-27 |
| JPS62116510A (ja) | 1987-05-28 |
| EP0214017A2 (de) | 1987-03-11 |
| US4835184A (en) | 1989-05-30 |
| FR2585572B3 (fr) | 1987-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |