DK142321B - Analogifremgangsmåde til fremstilling af D-6-methyl-8-(2-methylsulfinylethyl)-ergolin og syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af D-6-methyl-8-(2-methylsulfinylethyl)-ergolin og syreadditionssalte deraf. Download PDF

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Publication number
DK142321B
DK142321B DK547575AA DK547575A DK142321B DK 142321 B DK142321 B DK 142321B DK 547575A A DK547575A A DK 547575AA DK 547575 A DK547575 A DK 547575A DK 142321 B DK142321 B DK 142321B
Authority
DK
Denmark
Prior art keywords
ergoline
methyl
acid
methylsulfinylethyl
prolactin
Prior art date
Application number
DK547575AA
Other languages
Danish (da)
English (en)
Other versions
DK142321C (sv
DK547575A (sv
Inventor
Edmund Carl Kornfeld
Nicholas James Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK547575A publication Critical patent/DK547575A/da
Publication of DK142321B publication Critical patent/DK142321B/da
Application granted granted Critical
Publication of DK142321C publication Critical patent/DK142321C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK547575AA 1974-12-06 1975-12-04 Analogifremgangsmåde til fremstilling af D-6-methyl-8-(2-methylsulfinylethyl)-ergolin og syreadditionssalte deraf. DK142321B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/530,318 US3985752A (en) 1974-12-06 1974-12-06 6-Methyl-8-(substituted) methylergolines
US53031874 1974-12-06

Publications (3)

Publication Number Publication Date
DK547575A DK547575A (sv) 1976-06-07
DK142321B true DK142321B (da) 1980-10-13
DK142321C DK142321C (sv) 1981-03-09

Family

ID=24113213

Family Applications (2)

Application Number Title Priority Date Filing Date
DK547575AA DK142321B (da) 1974-12-06 1975-12-04 Analogifremgangsmåde til fremstilling af D-6-methyl-8-(2-methylsulfinylethyl)-ergolin og syreadditionssalte deraf.
DK547675A DK547675A (da) 1974-12-06 1975-12-04 Fremgangsmade til fremstilling af 6-methyl-8beta-substituerede methylergoliner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK547675A DK547675A (da) 1974-12-06 1975-12-04 Fremgangsmade til fremstilling af 6-methyl-8beta-substituerede methylergoliner

Country Status (29)

Country Link
US (1) US3985752A (sv)
JP (2) JPS5946235B2 (sv)
AR (2) AR207664A1 (sv)
AT (2) AT348141B (sv)
AU (1) AU498226B2 (sv)
BE (1) BE836308A (sv)
BG (3) BG33435A3 (sv)
CA (2) CA1062252A (sv)
CH (2) CH617197A5 (sv)
CS (2) CS200483B2 (sv)
DD (2) DD123749A5 (sv)
DE (1) DE2554000A1 (sv)
DK (2) DK142321B (sv)
ES (3) ES443276A1 (sv)
FR (1) FR2293203A1 (sv)
GB (1) GB1526835A (sv)
GR (2) GR60025B (sv)
HU (3) HU173847B (sv)
IE (1) IE42372B1 (sv)
IL (1) IL48573A (sv)
MX (1) MX3113E (sv)
NL (1) NL7514058A (sv)
PH (1) PH12630A (sv)
PL (3) PL102195B1 (sv)
RO (2) RO64281A (sv)
SE (2) SE421423B (sv)
SU (3) SU685155A3 (sv)
YU (2) YU304875A (sv)
ZA (1) ZA757624B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
HU180467B (en) * 1979-07-12 1983-03-28 Gyogyszerkutato Intezet Process for producing new ergol-8-ene- and ergoline-sceleted compounds
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
JPH0541005Y2 (sv) * 1987-07-14 1993-10-18
JPH02174820A (ja) * 1988-12-27 1990-07-06 Sekisui Chem Co Ltd トイレット
WO2000054776A1 (en) * 1999-03-17 2000-09-21 Eugen Eigenmann Use of prolactin inhibitors for the treatment of fertility problems in animal species
US20070243240A9 (en) * 2000-08-24 2007-10-18 Fred Windt-Hanke Transdermal therapeutic system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL28388A (en) * 1966-07-29 1971-11-29 Farma Italia Soc History 1, 6 - Dimethyl - A 01 - Argolin
CH507248A (de) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure

Also Published As

Publication number Publication date
IE42372B1 (en) 1980-07-30
ZA757624B (en) 1977-07-27
SU724085A3 (ru) 1980-03-25
BE836308A (fr) 1976-06-08
ES443276A1 (es) 1977-08-16
IE42372L (en) 1976-06-06
US3985752A (en) 1976-10-12
AT347050B (de) 1978-12-11
AR207664A1 (es) 1976-10-22
DD123749A5 (sv) 1977-01-12
DK142321C (sv) 1981-03-09
HU173724B (hu) 1979-07-28
FR2293203B1 (sv) 1978-07-28
USB530318I5 (sv) 1976-01-13
SE421422B (sv) 1981-12-21
YU304775A (en) 1982-02-28
HU175228B (hu) 1980-06-28
DE2554000A1 (de) 1976-06-16
SE421423B (sv) 1981-12-21
GR60025B (en) 1978-03-31
CA1062253A (en) 1979-09-11
AT348141B (de) 1979-01-25
PH12630A (en) 1979-07-05
JPS5182300A (sv) 1976-07-19
SE7513640L (sv) 1976-06-08
NL7514058A (nl) 1976-06-09
ES443275A1 (es) 1977-09-16
HU173847B (hu) 1979-09-28
CS199609B2 (en) 1980-07-31
JPS59210085A (ja) 1984-11-28
SE7513641L (sv) 1976-06-08
YU304875A (en) 1982-02-28
BG33435A3 (en) 1983-02-15
CA1062252A (en) 1979-09-11
RO65456A (ro) 1980-01-15
IL48573A (en) 1979-03-12
BG33288A3 (en) 1983-01-14
AR208104A1 (es) 1976-11-30
BG33287A3 (en) 1983-01-14
PL102198B1 (pl) 1979-03-31
ES457709A1 (es) 1978-03-01
MX3113E (es) 1980-04-18
GR60026B (en) 1978-03-31
DK547675A (da) 1976-06-07
IL48573A0 (en) 1976-01-30
JPS6017795B2 (ja) 1985-05-07
JPS5946235B2 (ja) 1984-11-10
DK547575A (sv) 1976-06-07
CS200483B2 (en) 1980-09-15
FR2293203A1 (fr) 1976-07-02
RO64281A (fr) 1979-07-15
GB1526835A (en) 1978-10-04
CH619465A5 (sv) 1980-09-30
AU8718275A (en) 1977-06-09
AU498226B2 (en) 1979-02-22
PL102195B1 (pl) 1979-03-31
SU694075A3 (ru) 1979-10-25
CH617197A5 (sv) 1980-05-14
ATA927975A (de) 1978-04-15
DD123748A5 (sv) 1977-01-12
ATA927875A (de) 1978-06-15
PL106884B1 (pl) 1980-01-31
SU685155A3 (ru) 1979-09-05

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