CH619465A5 - - Google Patents

Download PDF

Info

Publication number
CH619465A5
CH619465A5 CH1580175A CH1580175A CH619465A5 CH 619465 A5 CH619465 A5 CH 619465A5 CH 1580175 A CH1580175 A CH 1580175A CH 1580175 A CH1580175 A CH 1580175A CH 619465 A5 CH619465 A5 CH 619465A5
Authority
CH
Switzerland
Prior art keywords
methyl
compound
formula
ergoline
prolactin
Prior art date
Application number
CH1580175A
Other languages
German (de)
English (en)
Inventor
Edmund Carl Kornfeld
Nicholas James Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CH619465A5 publication Critical patent/CH619465A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1580175A 1974-12-06 1975-12-04 CH619465A5 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/530,318 US3985752A (en) 1974-12-06 1974-12-06 6-Methyl-8-(substituted) methylergolines

Publications (1)

Publication Number Publication Date
CH619465A5 true CH619465A5 (sv) 1980-09-30

Family

ID=24113213

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1580275A CH617197A5 (sv) 1974-12-06 1975-12-04
CH1580175A CH619465A5 (sv) 1974-12-06 1975-12-04

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1580275A CH617197A5 (sv) 1974-12-06 1975-12-04

Country Status (29)

Country Link
US (1) US3985752A (sv)
JP (2) JPS5946235B2 (sv)
AR (2) AR207664A1 (sv)
AT (2) AT348141B (sv)
AU (1) AU498226B2 (sv)
BE (1) BE836308A (sv)
BG (3) BG33435A3 (sv)
CA (2) CA1062252A (sv)
CH (2) CH617197A5 (sv)
CS (2) CS200483B2 (sv)
DD (2) DD123749A5 (sv)
DE (1) DE2554000A1 (sv)
DK (2) DK142321B (sv)
ES (3) ES443276A1 (sv)
FR (1) FR2293203A1 (sv)
GB (1) GB1526835A (sv)
GR (2) GR60025B (sv)
HU (3) HU173847B (sv)
IE (1) IE42372B1 (sv)
IL (1) IL48573A (sv)
MX (1) MX3113E (sv)
NL (1) NL7514058A (sv)
PH (1) PH12630A (sv)
PL (3) PL102195B1 (sv)
RO (2) RO64281A (sv)
SE (2) SE421423B (sv)
SU (3) SU685155A3 (sv)
YU (2) YU304875A (sv)
ZA (1) ZA757624B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
HU180467B (en) * 1979-07-12 1983-03-28 Gyogyszerkutato Intezet Process for producing new ergol-8-ene- and ergoline-sceleted compounds
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
JPH0541005Y2 (sv) * 1987-07-14 1993-10-18
JPH02174820A (ja) * 1988-12-27 1990-07-06 Sekisui Chem Co Ltd トイレット
WO2000054776A1 (en) * 1999-03-17 2000-09-21 Eugen Eigenmann Use of prolactin inhibitors for the treatment of fertility problems in animal species
US20070243240A9 (en) * 2000-08-24 2007-10-18 Fred Windt-Hanke Transdermal therapeutic system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL28388A (en) * 1966-07-29 1971-11-29 Farma Italia Soc History 1, 6 - Dimethyl - A 01 - Argolin
CH507248A (de) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure

Also Published As

Publication number Publication date
IE42372B1 (en) 1980-07-30
ZA757624B (en) 1977-07-27
SU724085A3 (ru) 1980-03-25
BE836308A (fr) 1976-06-08
ES443276A1 (es) 1977-08-16
IE42372L (en) 1976-06-06
US3985752A (en) 1976-10-12
AT347050B (de) 1978-12-11
AR207664A1 (es) 1976-10-22
DD123749A5 (sv) 1977-01-12
DK142321C (sv) 1981-03-09
HU173724B (hu) 1979-07-28
FR2293203B1 (sv) 1978-07-28
USB530318I5 (sv) 1976-01-13
SE421422B (sv) 1981-12-21
YU304775A (en) 1982-02-28
HU175228B (hu) 1980-06-28
DE2554000A1 (de) 1976-06-16
SE421423B (sv) 1981-12-21
GR60025B (en) 1978-03-31
CA1062253A (en) 1979-09-11
AT348141B (de) 1979-01-25
PH12630A (en) 1979-07-05
JPS5182300A (sv) 1976-07-19
SE7513640L (sv) 1976-06-08
NL7514058A (nl) 1976-06-09
ES443275A1 (es) 1977-09-16
HU173847B (hu) 1979-09-28
CS199609B2 (en) 1980-07-31
JPS59210085A (ja) 1984-11-28
SE7513641L (sv) 1976-06-08
YU304875A (en) 1982-02-28
BG33435A3 (en) 1983-02-15
CA1062252A (en) 1979-09-11
RO65456A (ro) 1980-01-15
IL48573A (en) 1979-03-12
BG33288A3 (en) 1983-01-14
AR208104A1 (es) 1976-11-30
BG33287A3 (en) 1983-01-14
PL102198B1 (pl) 1979-03-31
ES457709A1 (es) 1978-03-01
MX3113E (es) 1980-04-18
GR60026B (en) 1978-03-31
DK547675A (da) 1976-06-07
IL48573A0 (en) 1976-01-30
JPS6017795B2 (ja) 1985-05-07
JPS5946235B2 (ja) 1984-11-10
DK547575A (sv) 1976-06-07
CS200483B2 (en) 1980-09-15
FR2293203A1 (fr) 1976-07-02
RO64281A (fr) 1979-07-15
GB1526835A (en) 1978-10-04
AU8718275A (en) 1977-06-09
AU498226B2 (en) 1979-02-22
PL102195B1 (pl) 1979-03-31
SU694075A3 (ru) 1979-10-25
CH617197A5 (sv) 1980-05-14
ATA927975A (de) 1978-04-15
DD123748A5 (sv) 1977-01-12
ATA927875A (de) 1978-06-15
PL106884B1 (pl) 1980-01-31
DK142321B (da) 1980-10-13
SU685155A3 (ru) 1979-09-05

Similar Documents

Publication Publication Date Title
DE1695556C3 (de) 3-Alkyl-1,2,3,4,4a,9-hexahydropyrazino[1,2-f]morphanthridinderivate
DD141928A5 (de) Verfahren zur herstellung neuer ergolinderivate
WO1980000152A1 (en) 3-aminopropoxy-aryl derivates,preparation and use thereof
DE3525564A1 (de) Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3200304A1 (de) 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE2300107C2 (de) Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen
EP0528922A1 (de) Neue sulfonylverbindungen
CH617196A5 (sv)
DE2407115B2 (de) 2,6-Dimethyl-l,4-dihydropyridin-3carbonsäureamino-alkylesterderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung
CH619465A5 (sv)
DE2928187A1 (de) Optisch aktive oder racemische brom- 14-oxo-e-homoeburnanderivate, verfahren zur herstellung derselben und von optisch aktiven oder racemischen 11-bromvincaminsaeureesterderivaten und optisch aktive oder racemische 11-bromvincaminsaeureesterderivate sowie erstere oder letztere enthaltende arzneimittel
DE2302866A1 (de) Neue 1-substituierte-1,4-dihydropyridinderivate
DE2554629A1 (de) 8,8-disubstituierte-6-methylergoline
EP0705830A1 (de) 2,3-Cyclisch kondensierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als selektive Kaliumkanalmodulatoren
DD239794A5 (de) Verfahren zur herstellung von 4-alkoxy-pyrido(2,3-d)-pyrimidin-derivaten
DE3118521A1 (de) Dibenzo(de,g)chinolin-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von erkaeltungskrankheiten und allergien
EP0665228A1 (de) Neue 3-Phenylsulfonyl-3,7-diazabicyclo(3,3,1)nonan-Verbindungen enthaltende Arzneimittel
EP0473963A1 (de) Neue Pyrrolobenzimidazole, Imidazobenzoxazinone und Imidazochinolone, Verfahren zu ihrer Herstellung und ihre Verwendung sowie die Verbindungen enthaltende Zubereitungen
DE2601473A1 (de) 2,3-dihydroergoline und verfahren zu ihrer herstellung
EP0665014B1 (de) 3-Benzoyl-3,7-diazabicyclo(3,3,1)nonan-Verbindungen mit anti-arrhythmischer Wirkung
DE2335750A1 (de) D-6-methyl-2,8-disubst.-ergoline
EP0045911B1 (de) Neue Aminopropanol-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0180833B1 (de) 4-Oxo-pyrido[2,3]pyrimidin-Derivate, Verfahren zur deren Herstellung und diese ethaltende Arzneimittel
DD154487A5 (de) Verfahren zur herstellung von 1-benzoxepin-5(2h)-on-derivaten
DD144671A5 (de) Verfahren zur herstellung von 2-azaergolinen und 2-aza-8(oder 9)ergolenen

Legal Events

Date Code Title Description
PL Patent ceased