DK1411053T3 - Fremgangsmåde til opnåelse af derivater af [[(pyridilsubstitueret)methyl]thio]benzimidazol - Google Patents
Fremgangsmåde til opnåelse af derivater af [[(pyridilsubstitueret)methyl]thio]benzimidazolInfo
- Publication number
- DK1411053T3 DK1411053T3 DK01919463T DK01919463T DK1411053T3 DK 1411053 T3 DK1411053 T3 DK 1411053T3 DK 01919463 T DK01919463 T DK 01919463T DK 01919463 T DK01919463 T DK 01919463T DK 1411053 T3 DK1411053 T3 DK 1411053T3
- Authority
- DK
- Denmark
- Prior art keywords
- methyl
- alkoxy
- substituted
- thio
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200000989A ES2171116B1 (es) | 2000-04-14 | 2000-04-14 | Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol. |
PCT/ES2001/000143 WO2001079194A1 (es) | 2000-04-14 | 2001-04-10 | Procedimiento para la obtención de derivados de [[(piridil sustituido)metil]tio]bencimidazol |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1411053T3 true DK1411053T3 (da) | 2007-09-24 |
Family
ID=8493207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01919463T DK1411053T3 (da) | 2000-04-14 | 2001-04-10 | Fremgangsmåde til opnåelse af derivater af [[(pyridilsubstitueret)methyl]thio]benzimidazol |
Country Status (18)
Country | Link |
---|---|
US (1) | US6723852B2 (ja) |
EP (1) | EP1411053B1 (ja) |
JP (1) | JP2003531144A (ja) |
KR (1) | KR100757346B1 (ja) |
CN (1) | CN1214027C (ja) |
AT (1) | ATE363479T1 (ja) |
AU (1) | AU780314B2 (ja) |
CA (1) | CA2405304C (ja) |
CY (1) | CY1106632T1 (ja) |
DE (1) | DE60128736T2 (ja) |
DK (1) | DK1411053T3 (ja) |
ES (2) | ES2171116B1 (ja) |
HU (1) | HUP0300583A2 (ja) |
MX (1) | MXPA02010039A (ja) |
NO (1) | NO323468B1 (ja) |
NZ (1) | NZ521930A (ja) |
PT (1) | PT1411053E (ja) |
WO (1) | WO2001079194A1 (ja) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2185459B1 (es) | 2000-10-02 | 2003-12-16 | Dinamite Dipharma Spa | Procedimiento para la obtencion de pantoprazol y compuestos intermedios para el mismo. |
WO2004056804A2 (en) * | 2002-12-19 | 2004-07-08 | Teva Pharmaceutical Industries Ltd. | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates |
WO2004080961A2 (en) * | 2003-03-12 | 2004-09-23 | Teva Pharmaceutical Industries Ltd. | Crystalline and amorphous solids of pantoprazole and processes for their preparation |
CA2528993A1 (en) * | 2003-06-10 | 2004-12-23 | Teva Pharmaceutical Industries Ltd. | Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole |
ITMI20031813A1 (it) * | 2003-09-23 | 2005-03-24 | Dinamite Dipharma S P A In Forma A Bbreviata Diph | Procedimento per la preparazione di pantoprazolo e suoi sali. |
KR100771659B1 (ko) * | 2005-03-23 | 2007-10-30 | 주식회사 카이로제닉스 | 판토프라졸 및 그 중간체의 제조방법 |
CA2607583A1 (en) * | 2005-05-06 | 2007-04-05 | Medichem, S.A. | Pantoprazole free acid form iii |
DK2003130T3 (da) * | 2006-03-10 | 2011-12-12 | Arigen Pharmaceuticals Inc | Nyt pyridinderivat med anti-helicobacter pylori-aktivitet |
WO2008001392A2 (en) * | 2006-06-30 | 2008-01-03 | Msn Laboratories Limited | An improved process for the preparation of pantoprazole and its pharmaceutically acceptable salts |
DK2103608T3 (da) * | 2006-12-18 | 2012-09-17 | Arigen Pharmaceuticals Inc | Helicobacter pylori eradikerende middel med inhiberende virkning på mavesyresekretion |
WO2009010937A1 (en) | 2007-07-17 | 2009-01-22 | Ranbaxy Laboratories Limited | Process for the preparation op pantoprazole sodium and pantoprazole sodium sesquihydrate |
US20090076089A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched pantoprazole |
CN102020637B (zh) * | 2010-12-13 | 2014-09-10 | 浙江华义医药有限公司 | 5-二氟甲氧基-2-[[(3,4-二甲氧基-2-吡啶基)甲基]硫基]-1h-苯并咪唑制备法 |
CN103242297A (zh) * | 2013-05-20 | 2013-08-14 | 湖北宜恒茶油产业科技有限责任公司 | 一种5-二氟甲氧基-2-[[(4-氯-3-甲氧基-2-吡啶基)甲基]硫代]-1h-苯并咪唑一水合物的制备方法 |
CN103664886A (zh) * | 2013-12-06 | 2014-03-26 | 威海迪素制药有限公司 | 2-[[[4-(3-甲氧基丙氧基)-3-甲基吡啶-2-基]甲基]硫代]-1h-苯并咪唑的制备方法 |
CN105399729B (zh) * | 2015-12-21 | 2018-04-17 | 山东金城医药化工有限公司 | 奥美拉唑的合成方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8204879D0 (sv) * | 1982-08-26 | 1982-08-26 | Haessle Ab | Novel chemical intermediates |
HU195220B (en) * | 1983-05-03 | 1988-04-28 | Byk Gulden Lomberg Chem Fqb | Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them |
ZA854287B (en) * | 1984-06-16 | 1986-02-26 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridines,process for their preparation,their use and medicaments containing them |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
FR2593178B1 (fr) * | 1986-01-20 | 1988-04-29 | Esteve Labor Dr | Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments. |
JPH0674272B2 (ja) * | 1986-11-13 | 1994-09-21 | エーザイ株式会社 | ピリジン誘導体及びそれを含有する潰瘍治療剤 |
ES2026761A6 (es) * | 1990-10-31 | 1992-05-01 | Genesis Para La Investigacion | Procedimiento de obtencion del omeprazol. |
ES2024357A6 (es) * | 1990-12-05 | 1992-02-16 | Genesis Para La Investigacion | Procedimiento de obtencion de halohidrato de 2-halometil-3,5-dimetil-4-metoxipiri-dina. |
ES2036948B1 (es) * | 1991-11-21 | 1994-09-01 | Genesis Para La Investigacion | Procedimiento de obtencion de compuestos derivados de piridina. |
CA2175235A1 (en) * | 1993-10-29 | 1995-05-04 | Takeshi Kawakita | Pyridine compound and medicinal use thereof |
JP3828648B2 (ja) * | 1996-11-14 | 2006-10-04 | 武田薬品工業株式会社 | 2−(2−ピリジルメチルスルフィニル)ベンズイミダゾール系化合物の結晶およびその製造法 |
ID18983A (id) * | 1996-12-04 | 1998-05-28 | Lilly Co Eli | Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia |
GB9921578D0 (en) * | 1999-09-13 | 1999-11-17 | Cipla Limited | Omeprazole synthesis |
-
2000
- 2000-04-14 ES ES200000989A patent/ES2171116B1/es not_active Expired - Fee Related
-
2001
- 2001-04-10 KR KR1020027013675A patent/KR100757346B1/ko not_active IP Right Cessation
- 2001-04-10 US US10/204,604 patent/US6723852B2/en not_active Expired - Fee Related
- 2001-04-10 PT PT01919463T patent/PT1411053E/pt unknown
- 2001-04-10 CA CA2405304A patent/CA2405304C/en not_active Expired - Fee Related
- 2001-04-10 AU AU46551/01A patent/AU780314B2/en not_active Ceased
- 2001-04-10 HU HU0300583A patent/HUP0300583A2/hu unknown
- 2001-04-10 AT AT01919463T patent/ATE363479T1/de not_active IP Right Cessation
- 2001-04-10 MX MXPA02010039A patent/MXPA02010039A/es active IP Right Grant
- 2001-04-10 DE DE60128736T patent/DE60128736T2/de not_active Expired - Lifetime
- 2001-04-10 CN CNB018088791A patent/CN1214027C/zh not_active Expired - Fee Related
- 2001-04-10 ES ES01919463T patent/ES2284629T3/es not_active Expired - Lifetime
- 2001-04-10 EP EP01919463A patent/EP1411053B1/en not_active Expired - Lifetime
- 2001-04-10 NZ NZ521930A patent/NZ521930A/en unknown
- 2001-04-10 JP JP2001576794A patent/JP2003531144A/ja active Pending
- 2001-04-10 DK DK01919463T patent/DK1411053T3/da active
- 2001-04-10 WO PCT/ES2001/000143 patent/WO2001079194A1/es active IP Right Grant
-
2002
- 2002-10-08 NO NO20024858A patent/NO323468B1/no not_active IP Right Cessation
-
2007
- 2007-05-31 CY CY20071100725T patent/CY1106632T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2171116B1 (es) | 2003-08-01 |
WO2001079194A1 (es) | 2001-10-25 |
CA2405304C (en) | 2011-01-18 |
PT1411053E (pt) | 2007-07-12 |
NZ521930A (en) | 2004-07-30 |
CN1214027C (zh) | 2005-08-10 |
KR100757346B1 (ko) | 2007-09-11 |
AU780314B2 (en) | 2005-03-17 |
ATE363479T1 (de) | 2007-06-15 |
CY1106632T1 (el) | 2012-01-25 |
DE60128736D1 (de) | 2007-07-12 |
US6723852B2 (en) | 2004-04-20 |
HUP0300583A2 (hu) | 2003-07-28 |
NO323468B1 (no) | 2007-05-21 |
KR20030030990A (ko) | 2003-04-18 |
CA2405304A1 (en) | 2002-10-07 |
ES2171116A1 (es) | 2002-08-16 |
MXPA02010039A (es) | 2004-08-19 |
DE60128736T2 (de) | 2008-02-07 |
EP1411053B1 (en) | 2007-05-30 |
EP1411053A1 (en) | 2004-04-21 |
CN1427836A (zh) | 2003-07-02 |
AU4655101A (en) | 2001-10-30 |
NO20024858L (no) | 2002-12-06 |
WO2001079194A9 (es) | 2003-05-08 |
NO20024858D0 (no) | 2002-10-08 |
ES2284629T3 (es) | 2007-11-16 |
JP2003531144A (ja) | 2003-10-21 |
US20030036656A1 (en) | 2003-02-20 |
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