DK140878A - Fremgangsmaade til fremstilling af acetamidderivater - Google Patents

Fremgangsmaade til fremstilling af acetamidderivater

Info

Publication number
DK140878A
DK140878A DK140878A DK140878A DK140878A DK 140878 A DK140878 A DK 140878A DK 140878 A DK140878 A DK 140878A DK 140878 A DK140878 A DK 140878A DK 140878 A DK140878 A DK 140878A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
acetamide derivatives
acetamide
derivatives
Prior art date
Application number
DK140878A
Other languages
English (en)
Other versions
DK152207C (da
DK152207B (da
Inventor
L Lafon
Original Assignee
Lab L Lfon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab L Lfon filed Critical Lab L Lfon
Publication of DK140878A publication Critical patent/DK140878A/da
Publication of DK152207B publication Critical patent/DK152207B/da
Application granted granted Critical
Publication of DK152207C publication Critical patent/DK152207C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
DK140878A 1977-03-31 1978-03-30 Analogifremgangsmaade til fremstilling af sulfinylacetamid- eller malonamid-derivater eller syreadditionssalte deraf DK152207C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1357977 1977-03-31
GB13579/77A GB1584462A (en) 1977-03-31 1977-03-31 N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
DK140878A true DK140878A (da) 1978-10-01
DK152207B DK152207B (da) 1988-02-08
DK152207C DK152207C (da) 1988-07-11

Family

ID=10025527

Family Applications (1)

Application Number Title Priority Date Filing Date
DK140878A DK152207C (da) 1977-03-31 1978-03-30 Analogifremgangsmaade til fremstilling af sulfinylacetamid- eller malonamid-derivater eller syreadditionssalte deraf

Country Status (14)

Country Link
US (1) US4177290A (da)
JP (1) JPS53121724A (da)
BE (1) BE865468A (da)
CA (1) CA1091679A (da)
CH (1) CH628026A5 (da)
DE (2) DE2809625C2 (da)
DK (1) DK152207C (da)
ES (1) ES468378A1 (da)
FR (1) FR2385693A1 (da)
GB (1) GB1584462A (da)
IE (1) IE46566B1 (da)
IT (1) IT1094041B (da)
LU (2) LU79335A1 (da)
NL (2) NL188692C (da)

Families Citing this family (101)

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US4332967A (en) * 1980-06-19 1982-06-01 Petrolite Corporation Compounds containing sulfur and amino groups
US4539404A (en) * 1980-06-19 1985-09-03 Petrolite Corporation Pyrimidines containing sulfur and amino groups as corrosion inhibitors
US4684507A (en) * 1981-11-10 1987-08-04 Petrolite Corporation Process of corrosion inhibition using compounds containing sulfur and amino groups
US4450138A (en) * 1981-11-10 1984-05-22 Petrolite Corporation Processes for inhibiting corrosion using compounds containing sulfur and amino groups
US4450137A (en) * 1981-11-10 1984-05-22 Petrolite Corporation Processes for inhibiting corrosion using compounds containing sulfur and amino groups
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FR2528039A1 (fr) * 1982-06-04 1983-12-09 Lafon Labor Nouveaux derives de benzylsulfinylacetamide, utilisation en therapeutique et procede de preparation
FR2528038B2 (fr) * 1982-06-04 1985-08-09 Lafon Labor Derives de benzhydrylsulfinylacetamide et leur utilisation en therapeutique
FR2561646B1 (fr) * 1984-03-23 1987-10-09 Lafon Labor Derives d'acide (a-(alkylaminomethyl)-benzyl)-thioacetique, procede de preparation et utilisation en therapeutique
FR2584666B1 (fr) * 1985-07-10 1989-06-16 Champion Spark Plug Europ Bras moteur pour balai d'essuie-glace avec capuchon coulissant
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
FR2606015B1 (fr) * 1986-08-13 1989-05-19 Lafon Labor Derives du benzhydrylthiomethane, leurs procedes de preparation et leurs applications en therapeutique
FR2611709B1 (fr) * 1987-02-26 1989-06-09 Lafon Labor 2-(benzhydrylsulfonyl)acetamide, son procede de preparation et son application en therapeutique
FR2663225B1 (fr) 1990-06-14 1994-11-04 Lafon Labor Nouvelle utilisation du modafinil.
JPH0421903U (da) * 1990-06-18 1992-02-24
FR2684875B1 (fr) * 1991-12-13 1995-05-24 Lafon Labor Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique.
FR2697162B1 (fr) * 1992-10-23 1995-01-13 Lafon Labor Utilisation du modafinil pour la fabrication d'un médicament pour le traitement de l'incontinence urinaire et des troubles sphinctériens urétro vésicaux.
FR2706767B1 (da) * 1993-06-22 1995-09-08 Lafon Labor
FR2707637B1 (fr) * 1993-06-30 1995-10-06 Lafon Labor Nouveaux dérivés d'acétamide, leur procédé de préparation et leur utilisation en thérapeutique.
FR2708201B1 (fr) * 1993-06-30 1995-10-20 Lafon Labor Utilisation de dérivés d'acétamide pour la fabrication de médicaments.
US5618845A (en) * 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
FR2771004B1 (fr) * 1997-11-19 2000-02-18 Inst Curie Utilisation de derives de benzhydryl sulfinyle pour la fabrication de medicaments ayant un effet eveillant dans des situations de troubles de la vigilance d'origine medicamenteuse
US6346548B1 (en) 1999-08-16 2002-02-12 Cephalon, Inc. Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue
US6455588B1 (en) 1999-08-20 2002-09-24 Cephalon, Inc. Compositions including modafinil for treatment of eating disorders and for appetite stimulation
CN1249932A (zh) * 1999-09-29 2000-04-12 付俊昌 一种莫达芬尼及其光学对映体l及d异构体的新用途
FR2804322B1 (fr) 2000-01-31 2002-04-19 Lafon Labor Utilisation du modafinil pour la fabrication d'un medicament destine a corriger les troubles de la vigilance associes aux myopathies
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DE60219005T2 (de) * 2001-05-25 2007-12-13 Cephalon, Inc. Modafinil umfassende feste pharmazeutische Formulierungen
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
ITMI20020991A1 (it) * 2002-05-10 2003-11-10 Dinamite Dipharma S P A In For Procedimento per la sintesi del modafinil
US6875893B2 (en) * 2002-05-23 2005-04-05 Cephalon, Inc. Preparations of a sulfinyl acetamide
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US20040048931A1 (en) * 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US6992219B2 (en) * 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
TW200413296A (en) * 2002-08-09 2004-08-01 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
IL153098A0 (en) * 2002-11-26 2003-06-24 Chemagis Ltd Pharmaceutical compositions containing modafinil
FR2849029B1 (fr) * 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
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WO2004082630A2 (en) * 2003-03-17 2004-09-30 Neurohealing Pharmaceuticals, Inc. High potency dopaminergic treatment of neurological impairment associated with brain injury
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WO2005046854A2 (en) * 2003-09-12 2005-05-26 Sun Pharmaceutical Industries Limited A process for the preparation of diphenylmethylsulfinyl derivatives
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CN104672118A (zh) * 2014-12-12 2015-06-03 上海泓海荣通医药技术有限公司 一种莫达非尼多晶体的合成方法
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US11365195B2 (en) 2017-11-13 2022-06-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Atypical inhibitors of monoamine transporters; method of making; and use thereof
KR102126389B1 (ko) 2018-09-14 2020-06-25 셀라이온바이오메드 주식회사 벤즈히드릴티오 아세트아미드 화합물을 유효성분으로 포함하는 간 질환의 예방 또는 치료용 조성물
CN112789038A (zh) 2018-10-11 2021-05-11 诺华股份有限公司 H3r反向激动剂用于治疗与帕金森病(pd)相关的日间过度嗜睡的用途
KR102277739B1 (ko) 2019-12-11 2021-07-15 셀라이온바이오메드 주식회사 벤즈히드릴 티오 아세트아미드 화합물을 유효성분으로 포함하는 섬유화 질환의 치료용 조성물

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Also Published As

Publication number Publication date
DE2809625A1 (de) 1978-10-05
GB1584462A (en) 1981-02-11
CH628026A5 (fr) 1982-02-15
IE780433L (en) 1978-09-30
ES468378A1 (es) 1978-12-16
NL7803432A (nl) 1978-10-03
FR2385693B1 (da) 1980-04-11
IE46566B1 (en) 1983-07-27
BE865468A (fr) 1978-10-02
DK152207C (da) 1988-07-11
US4177290A (en) 1979-12-04
NL980003I2 (nl) 1998-05-06
JPS629103B2 (da) 1987-02-26
FR2385693A1 (fr) 1978-10-27
CA1091679A (en) 1980-12-16
LU79335A1 (fr) 1978-09-28
DE2809625C2 (de) 1985-05-09
NL188692C (nl) 1992-09-01
DK152207B (da) 1988-02-08
IT7821872A0 (it) 1978-03-31
LU90153I2 (fr) 1998-02-16
NL980003I1 (nl) 1998-03-02
IT1094041B (it) 1985-07-26
JPS53121724A (en) 1978-10-24
DE19875010I2 (de) 2001-06-13

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PBP Patent lapsed
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1997 00046, 971230

PUP Patent expired
CTFG Supplementary protection certificate (spc) issued

Free format text: CA 1997 00046, 971230, EXPIRES: 20030330