DK137007C - Analogifremgangsmaade til fremstilling af isoquinolinderivater - Google Patents

Analogifremgangsmaade til fremstilling af isoquinolinderivater

Info

Publication number
DK137007C
DK137007C DK639674A DK639674A DK137007C DK 137007 C DK137007 C DK 137007C DK 639674 A DK639674 A DK 639674A DK 639674 A DK639674 A DK 639674A DK 137007 C DK137007 C DK 137007C
Authority
DK
Denmark
Prior art keywords
preparation
isoquinoline derivatives
analogical procedure
analogical
procedure
Prior art date
Application number
DK639674A
Other languages
English (en)
Other versions
DK639674A (da
DK137007B (da
Inventor
W Mehrhof
R Pohlke
K H Becker
H-J Schliep
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of DK639674A publication Critical patent/DK639674A/da
Publication of DK137007B publication Critical patent/DK137007B/da
Application granted granted Critical
Publication of DK137007C publication Critical patent/DK137007C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK639674A 1973-12-10 1974-12-09 Analogifremgangsmaade til fremstilling af isoquinolinderivater DK137007C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2361390A DE2361390A1 (de) 1973-12-10 1973-12-10 Isochinolinderivate und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
DK639674A DK639674A (da) 1975-08-11
DK137007B DK137007B (da) 1978-01-02
DK137007C true DK137007C (da) 1978-06-05

Family

ID=5900348

Family Applications (1)

Application Number Title Priority Date Filing Date
DK639674A DK137007C (da) 1973-12-10 1974-12-09 Analogifremgangsmaade til fremstilling af isoquinolinderivater

Country Status (18)

Country Link
US (1) US3985881A (da)
JP (1) JPS5088077A (da)
AT (1) AT351026B (da)
BE (1) BE823027A (da)
CA (1) CA1053675A (da)
CH (1) CH605776A5 (da)
CS (1) CS188933B2 (da)
DD (1) DD115666A5 (da)
DE (1) DE2361390A1 (da)
DK (1) DK137007C (da)
ES (1) ES432716A1 (da)
FR (1) FR2253522B1 (da)
GB (1) GB1447611A (da)
HU (1) HU171483B (da)
IL (1) IL46160A0 (da)
NL (1) NL7416050A (da)
SE (1) SE7415247L (da)
ZA (1) ZA747820B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2504250A1 (de) * 1975-02-01 1976-08-05 Merck Patent Gmbh Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
US4556712A (en) * 1981-05-20 1985-12-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
DE3713743A1 (de) * 1987-04-24 1988-11-17 Boehringer Ingelheim Kg Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE97893T1 (de) * 1988-02-19 1993-12-15 Smithkline Beecham Farma 1,2,3,4-tetrahydroisoquinoline, verfharen zu ihrer herstellung und ihre verwendung als kappa- rezeptor agonisten.
KR890012970A (ko) * 1988-02-23 1989-09-20 추후보충 테트라히드로 이소퀴놀린 유도체
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
GB0225884D0 (en) * 2002-11-06 2002-12-11 Glaxo Group Ltd Novel compounds
PT2935222T (pt) * 2012-12-21 2018-12-10 Epizyme Inc Inibidores de prmt5 e seus usos
CN108026047A (zh) * 2015-09-01 2018-05-11 默克专利股份公司 吡喹酮及其前体的生产方法
US20180305334A1 (en) * 2015-10-14 2018-10-25 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules
KR20200094734A (ko) 2017-09-22 2020-08-07 주빌런트 에피파드 엘엘씨 Pad 억제제로서의 헤테로사이클릭 화합물
DK3697785T3 (da) 2017-10-18 2023-04-03 Jubilant Epipad LLC Imidazo-pyridine forbindelser som pad-inhibitorer
AU2018362046B2 (en) 2017-11-06 2023-04-13 Jubilant Prodel LLC Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
CA3083374A1 (en) 2017-11-24 2019-05-31 Jubilant Episcribe Llc Heterocyclic compounds as prmt5 inhibitors
AU2019234185A1 (en) 2018-03-13 2020-10-01 Jubilant Prodel LLC. Bicyclic compounds as inhibitors of PD1/PD-L1 interaction/activation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2612503A (en) * 1949-04-19 1952-09-30 Smith Kline French Lab Basic ether-substituted isoquinolines
US2640829A (en) * 1950-11-10 1953-06-02 Smith Kline French Lab Isoquinolyl heterocyclic ethers
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
US3483206A (en) * 1967-12-15 1969-12-09 Ciba Geigy Corp N-isoquinolylalkanoyl-n-arylamines
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils

Also Published As

Publication number Publication date
AU7625774A (en) 1976-06-10
CH605776A5 (da) 1978-10-13
SE7415247L (da) 1975-06-11
AT351026B (de) 1979-07-10
ZA747820B (en) 1975-12-31
DK639674A (da) 1975-08-11
ES432716A1 (es) 1977-03-01
DK137007B (da) 1978-01-02
BE823027A (fr) 1975-06-06
FR2253522B1 (da) 1978-06-30
GB1447611A (en) 1976-08-25
CA1053675A (en) 1979-05-01
PL93405B1 (da) 1977-05-30
HU171483B (hu) 1978-01-28
NL7416050A (nl) 1975-06-12
IL46160A0 (en) 1975-02-10
CS188933B2 (en) 1979-03-30
FR2253522A1 (da) 1975-07-04
JPS5088077A (da) 1975-07-15
DE2361390A1 (de) 1975-06-19
DD115666A5 (da) 1975-10-12
ATA981974A (de) 1978-12-15
US3985881A (en) 1976-10-12

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