NL7416050A - Werkwijze ter bereiding van isochinolinederi- vaten. - Google Patents

Werkwijze ter bereiding van isochinolinederi- vaten.

Info

Publication number
NL7416050A
NL7416050A NL7416050A NL7416050A NL7416050A NL 7416050 A NL7416050 A NL 7416050A NL 7416050 A NL7416050 A NL 7416050A NL 7416050 A NL7416050 A NL 7416050A NL 7416050 A NL7416050 A NL 7416050A
Authority
NL
Netherlands
Prior art keywords
isochinoline
deri
varies
preparing
preparing isochinoline
Prior art date
Application number
NL7416050A
Other languages
English (en)
Dutch (nl)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NL7416050A publication Critical patent/NL7416050A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NL7416050A 1973-12-10 1974-12-10 Werkwijze ter bereiding van isochinolinederi- vaten. NL7416050A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2361390A DE2361390A1 (de) 1973-12-10 1973-12-10 Isochinolinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
NL7416050A true NL7416050A (nl) 1975-06-12

Family

ID=5900348

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7416050A NL7416050A (nl) 1973-12-10 1974-12-10 Werkwijze ter bereiding van isochinolinederi- vaten.

Country Status (18)

Country Link
US (1) US3985881A (da)
JP (1) JPS5088077A (da)
AT (1) AT351026B (da)
BE (1) BE823027A (da)
CA (1) CA1053675A (da)
CH (1) CH605776A5 (da)
CS (1) CS188933B2 (da)
DD (1) DD115666A5 (da)
DE (1) DE2361390A1 (da)
DK (1) DK137007C (da)
ES (1) ES432716A1 (da)
FR (1) FR2253522B1 (da)
GB (1) GB1447611A (da)
HU (1) HU171483B (da)
IL (1) IL46160A0 (da)
NL (1) NL7416050A (da)
SE (1) SE7415247L (da)
ZA (1) ZA747820B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2504250A1 (de) * 1975-02-01 1976-08-05 Merck Patent Gmbh Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
US4556712A (en) * 1981-05-20 1985-12-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
DE3713743A1 (de) * 1987-04-24 1988-11-17 Boehringer Ingelheim Kg Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0330360B1 (en) * 1988-02-19 1993-12-01 SmithKline Beecham Farmaceutici S.p.A. 1,2,3,4-Tetrahydroisoquinolines, processes for their preparation, and their use as kappa-receptor agonists
KR890012970A (ko) * 1988-02-23 1989-09-20 추후보충 테트라히드로 이소퀴놀린 유도체
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
GB0225884D0 (en) * 2002-11-06 2002-12-11 Glaxo Group Ltd Novel compounds
HUE040323T2 (hu) 2012-12-21 2019-02-28 Epizyme Inc PRMT5-inhibitorok és alkalmazásaik
WO2017036577A1 (en) * 2015-09-01 2017-03-09 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
WO2017066705A1 (en) * 2015-10-14 2017-04-20 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules
KR20200094734A (ko) 2017-09-22 2020-08-07 주빌런트 에피파드 엘엘씨 Pad 억제제로서의 헤테로사이클릭 화합물
BR112020007607A2 (pt) 2017-10-18 2020-09-29 Jubilant Epipad LLC compostos das fórmulas (i), (ii) e (iii); processos de preparação de compostos das fórmulas (i), (ii) e (iii); composição farmacêutica; compostos; método para a inibição de uma ou mais famílias de pad em uma célula; método de tratamento de uma afecção mediada por uma ou mais pad; composto da fórmula (i), fórmula (ii) e fórmula (iii); uso do composto; método para o tratamento e/ou prevenção de uma afecção; método para o tratamento de artrite reumatoide; e método de tratamento de câncer
KR20200085836A (ko) 2017-11-06 2020-07-15 주빌런트 프로델 엘엘씨 Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체
PL3704120T3 (pl) 2017-11-24 2024-09-16 Jubilant Episcribe Llc Związki heterocykliczne jako inhibitory prmt5
BR112020018610A2 (pt) 2018-03-13 2020-12-29 Jubilant Prodel LLC Compostos de fórmula i, fórmula ii, fórmula iii, fórmula iv, fórmula v, fórmula vi, ou seus polimorfos, estereoisômeros, tautômeros, profármacos, solvatos e sais farmaceuticamente aceitáveis dos mesmos e uso dos mesmos; processo de preparação; composição farmacêutica; e método para o tratamento e/ou prevenção de várias doenças, que incluem câncer e doenças infecciosas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2612503A (en) * 1949-04-19 1952-09-30 Smith Kline French Lab Basic ether-substituted isoquinolines
US2640829A (en) * 1950-11-10 1953-06-02 Smith Kline French Lab Isoquinolyl heterocyclic ethers
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
US3483206A (en) * 1967-12-15 1969-12-09 Ciba Geigy Corp N-isoquinolylalkanoyl-n-arylamines
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils

Also Published As

Publication number Publication date
AU7625774A (en) 1976-06-10
DE2361390A1 (de) 1975-06-19
DD115666A5 (da) 1975-10-12
US3985881A (en) 1976-10-12
ZA747820B (en) 1975-12-31
CA1053675A (en) 1979-05-01
FR2253522A1 (da) 1975-07-04
ES432716A1 (es) 1977-03-01
PL93405B1 (da) 1977-05-30
DK137007C (da) 1978-06-05
CS188933B2 (en) 1979-03-30
IL46160A0 (en) 1975-02-10
SE7415247L (da) 1975-06-11
AT351026B (de) 1979-07-10
BE823027A (fr) 1975-06-06
CH605776A5 (da) 1978-10-13
DK639674A (da) 1975-08-11
JPS5088077A (da) 1975-07-15
DK137007B (da) 1978-01-02
ATA981974A (de) 1978-12-15
GB1447611A (en) 1976-08-25
FR2253522B1 (da) 1978-06-30
HU171483B (hu) 1978-01-28

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Legal Events

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BV The patent application has lapsed