BE823027A - Derives d'isoquinoleine et leur procede de preparation - Google Patents
Derives d'isoquinoleine et leur procede de preparationInfo
- Publication number
- BE823027A BE823027A BE151221A BE151221A BE823027A BE 823027 A BE823027 A BE 823027A BE 151221 A BE151221 A BE 151221A BE 151221 A BE151221 A BE 151221A BE 823027 A BE823027 A BE 823027A
- Authority
- BE
- Belgium
- Prior art keywords
- isoquinoleine
- derivatives
- preparation process
- preparation
- isoquinoleine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2361390A DE2361390A1 (de) | 1973-12-10 | 1973-12-10 | Isochinolinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE823027A true BE823027A (fr) | 1975-06-06 |
Family
ID=5900348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE151221A BE823027A (fr) | 1973-12-10 | 1974-12-06 | Derives d'isoquinoleine et leur procede de preparation |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3985881A (xx) |
| JP (1) | JPS5088077A (xx) |
| AT (1) | AT351026B (xx) |
| BE (1) | BE823027A (xx) |
| CA (1) | CA1053675A (xx) |
| CH (1) | CH605776A5 (xx) |
| CS (1) | CS188933B2 (xx) |
| DD (1) | DD115666A5 (xx) |
| DE (1) | DE2361390A1 (xx) |
| DK (1) | DK137007C (xx) |
| ES (1) | ES432716A1 (xx) |
| FR (1) | FR2253522B1 (xx) |
| GB (1) | GB1447611A (xx) |
| HU (1) | HU171483B (xx) |
| IL (1) | IL46160A0 (xx) |
| NL (1) | NL7416050A (xx) |
| SE (1) | SE7415247L (xx) |
| ZA (1) | ZA747820B (xx) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2504250A1 (de) * | 1975-02-01 | 1976-08-05 | Merck Patent Gmbh | Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung |
| US4232160A (en) * | 1978-10-18 | 1980-11-04 | Miles Laboratories, Inc. | Isoquinoline propionamides exhibiting analgesic properties |
| US4556712A (en) * | 1981-05-20 | 1985-12-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines |
| GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
| DE3713743A1 (de) * | 1987-04-24 | 1988-11-17 | Boehringer Ingelheim Kg | Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE68910999T2 (de) * | 1988-02-19 | 1994-03-24 | Smithkline Beecham Farma | 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten. |
| PT89780A (pt) * | 1988-02-23 | 1989-10-04 | Glaxo Group Ltd | Processo para a preparacao de derivados da tetrahidroisoquinolina |
| DE3827727A1 (de) * | 1988-08-16 | 1990-02-22 | Boehringer Ingelheim Kg | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
| GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
| US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
| GB0225884D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| US9604930B2 (en) * | 2012-12-21 | 2017-03-28 | Epizyme, Inc. | Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof |
| BR112018002881B1 (pt) * | 2015-09-01 | 2022-06-07 | Merck Patent Gmbh | Métodos para produção de praziquantel e de seus precursores |
| CA3001857A1 (en) * | 2015-10-14 | 2017-04-20 | Aquinnah Pharmaceuticals, Inc. | Compounds, compositions and methods of use against stress granules |
| CN111108105B (zh) | 2017-09-22 | 2023-03-31 | 朱比兰特埃皮帕德有限公司 | 作为pad抑制剂的杂环化合物 |
| PL3697785T3 (pl) | 2017-10-18 | 2023-08-07 | Jubilant Epipad LLC | Związki imidazopirydynowe jako inhibitory pad |
| JP7279057B6 (ja) | 2017-11-06 | 2024-02-15 | ジュビラント プローデル エルエルシー | Ｐｄ１／ｐｄ－ｌ１活性化の阻害剤としてのピリミジン誘導体 |
| LT3704120T (lt) | 2017-11-24 | 2024-06-25 | Jubilant Episcribe Llc | Heterocikliniai junginiai kaip prmt5 inhibitoriai |
| CN112105610B (zh) | 2018-03-13 | 2024-01-26 | 朱比连特普罗德尔有限责任公司 | 作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2612503A (en) * | 1949-04-19 | 1952-09-30 | Smith Kline French Lab | Basic ether-substituted isoquinolines |
| US2640829A (en) * | 1950-11-10 | 1953-06-02 | Smith Kline French Lab | Isoquinolyl heterocyclic ethers |
| US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
| US3483206A (en) * | 1967-12-15 | 1969-12-09 | Ciba Geigy Corp | N-isoquinolylalkanoyl-n-arylamines |
| US3600394A (en) * | 1968-05-17 | 1971-08-17 | Searle & Co | 2-aminoalkyl-3-arylisocarbostyrils |
-
1973
- 1973-12-10 DE DE2361390A patent/DE2361390A1/de active Pending
-
1974
- 1974-11-29 IL IL46160A patent/IL46160A0/xx unknown
- 1974-12-05 SE SE7415247A patent/SE7415247L/xx unknown
- 1974-12-06 FR FR7440041A patent/FR2253522B1/fr not_active Expired
- 1974-12-06 CS CS748365A patent/CS188933B2/cs unknown
- 1974-12-06 CA CA215,386A patent/CA1053675A/en not_active Expired
- 1974-12-06 BE BE151221A patent/BE823027A/xx unknown
- 1974-12-09 ZA ZA00747820A patent/ZA747820B/xx unknown
- 1974-12-09 DD DD182514A patent/DD115666A5/xx unknown
- 1974-12-09 DK DK639674A patent/DK137007C/da active
- 1974-12-09 JP JP49141945A patent/JPS5088077A/ja active Pending
- 1974-12-09 AT AT981974A patent/AT351026B/de not_active IP Right Cessation
- 1974-12-09 HU HU74ME00001812A patent/HU171483B/hu unknown
- 1974-12-09 CH CH1632774A patent/CH605776A5/xx not_active IP Right Cessation
- 1974-12-09 US US05/530,551 patent/US3985881A/en not_active Expired - Lifetime
- 1974-12-09 GB GB5319174A patent/GB1447611A/en not_active Expired
- 1974-12-09 ES ES432716A patent/ES432716A1/es not_active Expired
- 1974-12-10 NL NL7416050A patent/NL7416050A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2253522B1 (xx) | 1978-06-30 |
| AT351026B (de) | 1979-07-10 |
| AU7625774A (en) | 1976-06-10 |
| IL46160A0 (en) | 1975-02-10 |
| NL7416050A (nl) | 1975-06-12 |
| ATA981974A (de) | 1978-12-15 |
| CH605776A5 (xx) | 1978-10-13 |
| SE7415247L (xx) | 1975-06-11 |
| ES432716A1 (es) | 1977-03-01 |
| US3985881A (en) | 1976-10-12 |
| DK639674A (xx) | 1975-08-11 |
| GB1447611A (en) | 1976-08-25 |
| DD115666A5 (xx) | 1975-10-12 |
| FR2253522A1 (xx) | 1975-07-04 |
| DK137007B (da) | 1978-01-02 |
| HU171483B (hu) | 1978-01-28 |
| ZA747820B (en) | 1975-12-31 |
| PL93405B1 (xx) | 1977-05-30 |
| DK137007C (da) | 1978-06-05 |
| CS188933B2 (en) | 1979-03-30 |
| JPS5088077A (xx) | 1975-07-15 |
| CA1053675A (en) | 1979-05-01 |
| DE2361390A1 (de) | 1975-06-19 |
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