ES432716A1 - Procedimiento para la obtencion de derivados de isoquinoli- na. - Google Patents
Procedimiento para la obtencion de derivados de isoquinoli- na.Info
- Publication number
- ES432716A1 ES432716A1 ES432716A ES432716A ES432716A1 ES 432716 A1 ES432716 A1 ES 432716A1 ES 432716 A ES432716 A ES 432716A ES 432716 A ES432716 A ES 432716A ES 432716 A1 ES432716 A1 ES 432716A1
- Authority
- ES
- Spain
- Prior art keywords
- bond
- methyl
- isoquinoline derivatives
- trimethoxybenzamido
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2361390A DE2361390A1 (de) | 1973-12-10 | 1973-12-10 | Isochinolinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES432716A1 true ES432716A1 (es) | 1977-03-01 |
Family
ID=5900348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES432716A Expired ES432716A1 (es) | 1973-12-10 | 1974-12-09 | Procedimiento para la obtencion de derivados de isoquinoli- na. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3985881A (es) |
| JP (1) | JPS5088077A (es) |
| AT (1) | AT351026B (es) |
| BE (1) | BE823027A (es) |
| CA (1) | CA1053675A (es) |
| CH (1) | CH605776A5 (es) |
| CS (1) | CS188933B2 (es) |
| DD (1) | DD115666A5 (es) |
| DE (1) | DE2361390A1 (es) |
| DK (1) | DK137007C (es) |
| ES (1) | ES432716A1 (es) |
| FR (1) | FR2253522B1 (es) |
| GB (1) | GB1447611A (es) |
| HU (1) | HU171483B (es) |
| IL (1) | IL46160A0 (es) |
| NL (1) | NL7416050A (es) |
| SE (1) | SE7415247L (es) |
| ZA (1) | ZA747820B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2504250A1 (de) * | 1975-02-01 | 1976-08-05 | Merck Patent Gmbh | Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung |
| US4232160A (en) * | 1978-10-18 | 1980-11-04 | Miles Laboratories, Inc. | Isoquinoline propionamides exhibiting analgesic properties |
| US4556712A (en) * | 1981-05-20 | 1985-12-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines |
| GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
| DE3713743A1 (de) * | 1987-04-24 | 1988-11-17 | Boehringer Ingelheim Kg | Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| EP0330360B1 (en) * | 1988-02-19 | 1993-12-01 | SmithKline Beecham Farmaceutici S.p.A. | 1,2,3,4-Tetrahydroisoquinolines, processes for their preparation, and their use as kappa-receptor agonists |
| KR890012970A (ko) * | 1988-02-23 | 1989-09-20 | 추후보충 | 테트라히드로 이소퀴놀린 유도체 |
| DE3827727A1 (de) * | 1988-08-16 | 1990-02-22 | Boehringer Ingelheim Kg | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
| GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
| US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
| GB0225884D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| HUE040323T2 (hu) | 2012-12-21 | 2019-02-28 | Epizyme Inc | PRMT5-inhibitorok és alkalmazásaik |
| WO2017036577A1 (en) * | 2015-09-01 | 2017-03-09 | Merck Patent Gmbh | Method for the production of praziquantel and precursors thereof |
| WO2017066705A1 (en) * | 2015-10-14 | 2017-04-20 | Aquinnah Pharmaceuticals, Inc. | Compounds, compositions and methods of use against stress granules |
| KR20200094734A (ko) | 2017-09-22 | 2020-08-07 | 주빌런트 에피파드 엘엘씨 | Pad 억제제로서의 헤테로사이클릭 화합물 |
| BR112020007607A2 (pt) | 2017-10-18 | 2020-09-29 | Jubilant Epipad LLC | compostos das fórmulas (i), (ii) e (iii); processos de preparação de compostos das fórmulas (i), (ii) e (iii); composição farmacêutica; compostos; método para a inibição de uma ou mais famílias de pad em uma célula; método de tratamento de uma afecção mediada por uma ou mais pad; composto da fórmula (i), fórmula (ii) e fórmula (iii); uso do composto; método para o tratamento e/ou prevenção de uma afecção; método para o tratamento de artrite reumatoide; e método de tratamento de câncer |
| KR20200085836A (ko) | 2017-11-06 | 2020-07-15 | 주빌런트 프로델 엘엘씨 | Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체 |
| PL3704120T3 (pl) | 2017-11-24 | 2024-09-16 | Jubilant Episcribe Llc | Związki heterocykliczne jako inhibitory prmt5 |
| BR112020018610A2 (pt) | 2018-03-13 | 2020-12-29 | Jubilant Prodel LLC | Compostos de fórmula i, fórmula ii, fórmula iii, fórmula iv, fórmula v, fórmula vi, ou seus polimorfos, estereoisômeros, tautômeros, profármacos, solvatos e sais farmaceuticamente aceitáveis dos mesmos e uso dos mesmos; processo de preparação; composição farmacêutica; e método para o tratamento e/ou prevenção de várias doenças, que incluem câncer e doenças infecciosas |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2612503A (en) * | 1949-04-19 | 1952-09-30 | Smith Kline French Lab | Basic ether-substituted isoquinolines |
| US2640829A (en) * | 1950-11-10 | 1953-06-02 | Smith Kline French Lab | Isoquinolyl heterocyclic ethers |
| US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
| US3483206A (en) * | 1967-12-15 | 1969-12-09 | Ciba Geigy Corp | N-isoquinolylalkanoyl-n-arylamines |
| US3600394A (en) * | 1968-05-17 | 1971-08-17 | Searle & Co | 2-aminoalkyl-3-arylisocarbostyrils |
-
1973
- 1973-12-10 DE DE2361390A patent/DE2361390A1/de active Pending
-
1974
- 1974-11-29 IL IL46160A patent/IL46160A0/xx unknown
- 1974-12-05 SE SE7415247A patent/SE7415247L/xx unknown
- 1974-12-06 CS CS748365A patent/CS188933B2/cs unknown
- 1974-12-06 BE BE151221A patent/BE823027A/xx unknown
- 1974-12-06 CA CA215,386A patent/CA1053675A/en not_active Expired
- 1974-12-06 FR FR7440041A patent/FR2253522B1/fr not_active Expired
- 1974-12-09 CH CH1632774A patent/CH605776A5/xx not_active IP Right Cessation
- 1974-12-09 DK DK639674A patent/DK137007C/da active
- 1974-12-09 ZA ZA00747820A patent/ZA747820B/xx unknown
- 1974-12-09 US US05/530,551 patent/US3985881A/en not_active Expired - Lifetime
- 1974-12-09 GB GB5319174A patent/GB1447611A/en not_active Expired
- 1974-12-09 JP JP49141945A patent/JPS5088077A/ja active Pending
- 1974-12-09 DD DD182514A patent/DD115666A5/xx unknown
- 1974-12-09 HU HU74ME00001812A patent/HU171483B/hu unknown
- 1974-12-09 ES ES432716A patent/ES432716A1/es not_active Expired
- 1974-12-09 AT AT981974A patent/AT351026B/de not_active IP Right Cessation
- 1974-12-10 NL NL7416050A patent/NL7416050A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7625774A (en) | 1976-06-10 |
| DE2361390A1 (de) | 1975-06-19 |
| DD115666A5 (es) | 1975-10-12 |
| US3985881A (en) | 1976-10-12 |
| ZA747820B (en) | 1975-12-31 |
| CA1053675A (en) | 1979-05-01 |
| FR2253522A1 (es) | 1975-07-04 |
| PL93405B1 (es) | 1977-05-30 |
| DK137007C (da) | 1978-06-05 |
| CS188933B2 (en) | 1979-03-30 |
| IL46160A0 (en) | 1975-02-10 |
| SE7415247L (es) | 1975-06-11 |
| AT351026B (de) | 1979-07-10 |
| BE823027A (fr) | 1975-06-06 |
| CH605776A5 (es) | 1978-10-13 |
| DK639674A (es) | 1975-08-11 |
| JPS5088077A (es) | 1975-07-15 |
| DK137007B (da) | 1978-01-02 |
| ATA981974A (de) | 1978-12-15 |
| GB1447611A (en) | 1976-08-25 |
| NL7416050A (nl) | 1975-06-12 |
| FR2253522B1 (es) | 1978-06-30 |
| HU171483B (hu) | 1978-01-28 |
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